KEGG T01001: 6092

Homo sapiens (human): 6092

Entry

6092 CDS T01001

Gene name

ROBO2, SAX3

Definition

roundabout, axon guidance receptor, homolog 2 (Drosophila)

Orthology

K06754

roundabout, axon guidance receptor 2

Organism

hsa Homo sapiens (human)

Pathway

hsa04360

Axon guidance

Disease

H01037

Vesicoureteral reflux

Class

Organismal Systems; Development; Axon guidance [PATH:hsa04360]

SSDB

Motif

Pfam:

I-set Ig_2 Ig_3 ig V-set fn3 C2-set_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2EDJ 1UJT 1UEM

Position

3p12.3

AA seq 1394 aa
MARRHERVTRRMWTWAPGLLMMTVVFWGHQGNGQGQGSRLRQEDFPPRIVEHPSDVIVSK
GEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPD
EGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPT
IYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFER
PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTM
STDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPA
VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKA
QLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPR
ATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGP
PSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRG
LRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNP
VVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKK
GVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPP
PDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGV
KSEPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRR
KKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNE
IGNFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILH
SNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKN
NGSTWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEE
DDDRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQT
WHIQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSS
MDNLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPH
RREGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIG
YMGSNSQGQFTGEL

NT seq 4185 nt +upstreamnt +downstreamnt
atggccagaagacatgaacgtgtcactagaaggatgtggacatgggctccgggactgttg
atgatgactgtggtgttttggggtcatcaggggaatggacaaggccaaggatcgcgtctt
cgccaggaggactttcccccgcggattgtggagcatccttccgatgtcatcgtctctaag
ggcgagcccacgactctgaactgcaaggcggagggccggccaacgcccaccattgagtgg
tacaaagatggggagcgagtggagactgacaaggacgatccccggtcccacaggatgctt
ctgcccagcggatccttattcttcttgcgcatcgtgcacgggcgcaggagtaaacctgat
gaaggaagctacgtttgtgttgcgaggaactatcttggtgaagcagtgagtcgaaatgcg
tctctggaagtggcattgttacgagatgacttccgacaaaaccccacagatgttgtagtg
gcagctggagagcctgcaatcctggagtgccagcctccccggggacacccagaacccacc
atctactggaaaaaagacaaagttcgaattgatgacaaggaagaaagaataagtatccgt
ggtggaaaactgatgatctccaataccaggaaaagtgatgcagggatgtatacttgtgtt
ggtaccaatatggtgggagaaagggacagtgacccagcagagctgactgtctttgaacga
cccacatttctcaggaggccaattaaccaggtggtactggaggaagaagctgtagaattt
cgttgtcaagtccaaggagatcctcaaccaactgtgaggtggaaaaaggatgatgcagac
ttgccaagaggaaggtatgacatcaaagacgattacacactaagaattaaaaagaccatg
agtacagatgaaggcacctatatgtgtattgctgagaatcgggttggaaaaatggaagcc
tctgctacactcaccgtccgagctcccccacagtttgtggttcggccaagagatcagatt
gttgctcaaggtcgaacagtgacatttccctgtgaaactaaaggaaacccacagccagct
gttttttggcagaaagaaggcagccagaacctacttttcccaaaccaaccccagcagccc
aacagtagatgctcagtgtcaccaactggagacctcacaatcaccaacattcaacgttcc
gacgcgggttactacatctgccaggctttaactgtggcaggaagcattttagcaaaagct
caactggaggttactgatgttttgacagatagacctccacctataattctacaaggccca
gccaaccaaacgctggcagtggatggtacagcgttactgaaatgtaaagccactggtgat
cctcttcctgtaattagctggttaaaggagggatttacttttccgggtagagatccaaga
gcaacaattcaagagcaaggcacactgcagattaagaatttacggatttctgatactggc
acttatacttgtgtggctacaagttcaagtggagagacttcctggagtgcagtgctggat
gtgacagagtctggagcaacaatcagtaaaaactatgatttaagtgacctgccagggcca
ccatccaaaccgcaggtcactgatgttactaagaacagtgtcaccttgtcctggcagcca
ggtacccctggaacccttccagcaagtgcatatatcattgaggctttcagccaatcagtg
agcaacagctggcagaccgtggcaaaccatgtaaagaccaccctctatactgtaagagga
ctgcggcccaatacaatctacttattcatggtcagagcgatcaacccccaaggtctcagt
gacccaagtcccatgtcagatcctgtgcgcacacaagatatcagcccaccagcacaagga
gtggaccacaggcaagtgcagaaagagctaggagatgtccttgtccgtcttcataatcca
gttgtgctgactcccaccacggttcaggtcacatggacggttgatcgccaaccccagttt
atccaaggctaccgagtgatgtatcgtcagacttcaggtctgcaggcgacatcttcgtgg
cagaatttagatgccaaagtcccgactgaacgaagtgctgtcttagtcaacctgaaaaag
ggggtgacttatgaaattaaagtacggccatattttaatgagttccaaggaatggatagt
gaatctaaaacggttcgtactactgaagaagccccaagtgccccaccacagtctgtcact
gtactgacagttggaagctacaatagcacaagtattagtgtttcctgggatcctcctcct
ccagatcaccagaatggaattatccaagaatacaagatctggtgtctaggaaatgaaacg
cgattccatatcaacaaaactgtggatgcagccattcggtccgtaataattggtggatta
ttcccaggtattcaataccgggtagaggttgcagctagtaccagtgcaggggttggagta
aagagtgagccacagccaataataatcgggagacgcaatgaagttgtcattactgaaaac
aataacagcataactgagcaaatcactgatgtggtgaagcaaccagcctttatagctggt
attggtggtgcctgctgggtaattctgatgggttttagcatatggttgtattggcgaaga
aagaagaggaagggactcagtaattatgctgttacgtttcaaagaggagatggaggacta
atgagcaatggaagccgtccaggtcttctcaatgctggtgatcccagctatccatggctt
gctgattcttggccagccacgagcttgccagtaaataatagcaacagtggcccaaatgag
attggaaattttggccgtggagatgtgctgccaccagttccaggccaaggggataaaaca
gcaacgatgctctcagatggagccatttatagtagcattgacttcactaccaaaaccagt
tacaacagttccagccaaataacacaggctaccccatatgccacgacacagatcttgcat
tccaacagcatacatgaattggctgtcgatctgcctgatccacaatggaaaagctcaatt
cagcaaaaaacagatctgatgggatttggttattctctacctgatcagaacaaaggtaac
aatggtgggaaaggtggaaaaaagaagaaaaataaaaactcttctaaaccacagaaaaac
aatggatccacttgggccaatgtccctctacctccccccccagtccagccccttcctggc
acggagctggaacactatgcagtggaacaacaagaaaatggctatgacagtgatagctgg
tgcccaccattgccagtacaaacttacttacaccaaggtctggaagatgaactggaagaa
gatgatgatagggtcccaacacctcctgttcgaggcgtggcttcttctcctgctatctcc
tttggacagcagtccactgcaactcttactccatccccacgggaagagatgcaacccatg
ctgcaggctcacctggatgagttgacaagagcctatcagtttgatatagcaaaacaaaca
tggcacattcaaagcaataatcaacctccacagcctccagttccaccgttaggttatgtg
tctggagccttgatttctgatttggaaacggatgttgcagatgatgatgccgacgacgaa
gaggaagctttagaaatccccaggcccctgagagcactggaccagactcctggatccagc
atggacaatctagacagctctgtgacaggaaaagcctttacctcctctcaaagacctcga
cctaccagcccattttctactgacagtaacaccagtgcagccctgagtcaaagtcagagg
cctcggcccactaaaaaacacaagggagggcggatggaccaacaaccagcattgcctcat
cgaagggaaggaatgacagatgaggaggccttggtgccctatagcaagcccagtttccca
tctccaggtggccacagctcatcaggaacagcttcttctaagggatccactggacctagg
aaaaccgaggtgttgagagcaggccaccagcgcaatgccagcgaccttcttgacatagga
tatatgggctccaacagtcaaggacagtttacaggtgaattatag

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (1)   
   HGNC (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (26)   
   RefSeq(nuc) (2)   
   GenBank (12)   
   EMBL (12)   
3D Structure (3)   
   PDB (3)   
Protein domain (7)   
   Pfam (7)   
All databases (61)   

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