KEGG   Homo sapiens (human): 6328Help
Entry
6328              CDS       T01001                                 

Gene name
SCN3A, NAC3, Nav1.3
Definition
(RefSeq) sodium voltage-gated channel alpha subunit 3
  KO
K04836  
voltage-gated sodium channel type III alpha
Organism
hsa  Homo sapiens (human)
Pathway
Taste transduction
Drug target
Ajmaline: 
Ambroxol (DG01073): 
Aminobenzoic acid (DG00379): 
Aprindine (DG00199): 
Benzocaine: 
Bunaftine: 
Bupivacaine (DG00801): 
Carbamazepine: 
Chloroprocaine (DG00800): 
Cibenzoline (DG00209): 
Cinchocaine (DG00297): 
Cocaine (DG00808): 
Disopyramide (DG00194): 
Dyclonine (DG00809): 
Encainide (DG00203): 
Eslicarbazepine (DG00848): 
Flecainide (DG00201): 
Fosphenytoin (DG00847): 
Hydroquinidine (DG01791): 
Lamotrigine: 
Levobupivacaine (DG00807): 
Lidocaine (DG00196): 
Mephenytoin: 
Mepivacaine (DG00802): 
Mexiletine (DG00197): 
Moracizine (DG00208): 
Oxcarbazepine: 
Phenytoin (DG00846): 
Pilsicainide (DG01257): 
Pirmenol (DG01381): 
Prilocaine (DG00803): 
Procainamide (DG00193): 
Procaine (DG00298): 
Propafenone (DG00200): 
Proxymetacaine (DG01145): 
Quinidine (DG00192): 
Ropivacaine (DG00806): 
Tetracaine (DG00296): 
Tocainide (DG00198): 
Topiramate: 
Zonisamide: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Organismal Systems
  Sensory system
   04742 Taste transduction
    6328 (SCN3A)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Na+ channel, SCN alpha, NaV1.x
   6328 (SCN3A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
2q24
AA seq 2000 aa AA seqDB search
MAQALLVPPGPESFRLFTRESLAAIEKRAAEEKAKKPKKEQDNDDENKPKPNSDLEAGKN
LPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVMNKGKAIFRFSATSALYILTPLNPVRKI
AIKILVHSLFSMLIMCTILTNCVFMTLSNPPDWTKNVEYTFTGIYTFESLIKILARGFCL
EDFTFLRDPWNWLDFSVIVMAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGAL
IQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPSDSAFETNTTSYFNGTMD
SNGTFVNVTMSTFNWKDYIGDDSHFYVLDGQKDPLLCGNGSDAGQCPEGYICVKAGRNPN
YGYTSFDTFSWAFLSLFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLVNLIL
AVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEEAQAVAAASAASRDFSGIGGLGE
LLESSSEASKLSSKSAKEWRNRRKKRRQREHLEGNNKGERDSFPKSESEDSVKRSSFLFS
MDGNRLTSDKKFCSPHQSLLSIRGSLFSPRRNSKTSIFSFRGRAKDVGSENDFADDEHST
FEDSESRRDSLFVPHRHGERRNSNVSQASMSSRMVPGLPANGKMHSTVDCNGVVSLVGGP
SALTSPTGQLPPEGTTTETEVRKRRLSSYQISMEMLEDSSGRQRAVSIASILTNTMEELE
ESRQKCPPCWYRFANVFLIWDCCDAWLKVKHLVNLIVMDPFVDLAITICIVLNTLFMAME
HYPMTEQFSSVLTVGNLVFTGIFTAEMVLKIIAMDPYYYFQEGWNIFDGIIVSLSLMELG
LSNVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVG
MQLFGKSYKECVCKINDDCTLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMC
LIVFMLVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDYVKN
KMRECFQKAFFRKPKVIEIHEGNKIDSCMSNNTGIEISKELNYLRDGNGTTSGVGTGSSV
EKYVIDENDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESELEESKEKLNATSSSE
GSTVDVVLPREGEQAETEPEEDLKPEACFTEGCIKKFPFCQVSTEEGKGKIWWNLRKTCY
SIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWV
AYGFQTYFTNAWCWLDFLIVDVSLVSLVANALGYSELGAIKSLRTLRALRPLRALSRFEG
MRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCVNMTTGNMFDISDVNN
LSDCQALGKQARWKNVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRDVKLQPVYEE
NLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLG
SKKPQKPIPRPANKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQGKYMTLVLSR
INLVFIVLFTGEFVLKLVSLRHYYFTIGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLF
RVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYV
KKEAGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSAPPDCDPDTIHPGSSVKGD
CGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKF
DPDATQFIEFSKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRV
LGESGEMDALRIQMEDRFMASNPSKVSYEPITTTLKRKQEEVSAAIIQRNFRCYLLKQRL
KNISSNYNKEAIKGRIDLPIKQDMIIDKLNGNSTPEKTDGSSSTTSPPSYDSVTKPDKEK
FEKDKPEKESKGKEVRENQK
NT seq 6003 nt NT seq  +upstreamnt  +downstreamnt
atggcacaggcactgttggtacccccaggacctgaaagcttccgcctttttactagagaa
tctcttgctgctatcgaaaaacgtgctgcagaagagaaagccaagaagcccaaaaaggaa
caagataatgatgatgagaacaaaccaaagccaaatagtgacttggaagctggaaagaac
cttccatttatttatggagacattcctccagagatggtgtcagagcccctggaggacctg
gatccctactatatcaataagaaaacttttatagtaatgaataaaggaaaggcaattttc
cgattcagtgccacctctgccttgtatattttaactccactaaaccctgttaggaaaatt
gctatcaagattttggtacattctttattcagcatgcttatcatgtgcactattttgacc
aactgtgtatttatgaccttgagcaaccctcctgactggacaaagaatgtagagtacaca
ttcactggaatctatacctttgagtcacttataaaaatcttggcaagagggttttgctta
gaagattttacgtttcttcgtgatccatggaactggctggatttcagtgtcattgtgatg
gcatatgtgacagagtttgtggacctgggcaatgtctcagcgttgagaacattcagagtt
ctccgagcactgaaaacaatttcagtcattccaggtttaaagaccattgtgggggccctg
atccagtcggtaaagaagctttctgatgtgatgatcctgactgtgttctgtctgagcgtg
tttgctctcattgggctgcagctgttcatgggcaatctgaggaataaatgtttgcagtgg
cccccaagcgattctgcttttgaaaccaacaccacttcctactttaatggcacaatggat
tcaaatgggacatttgttaatgtaacaatgagcacatttaactggaaggattacattgga
gatgacagtcacttttatgttttggatgggcaaaaagaccctttactctgtggaaatggc
tcagatgcaggccagtgtccagaaggatacatctgtgtgaaggctggtcgaaaccccaac
tatggctacacaagctttgacacctttagctgggctttcctgtctctatttcgactcatg
actcaagactactgggaaaatctttaccagttgacattacgtgctgctgggaaaacatac
atgatattttttgtcctggtcattttcttgggctcattttatttggtgaatttgatcctg
gctgtggtggccatggcctatgaggagcagaatcaggccaccttggaagaagcagaacaa
aaagaggccgaatttcagcagatgctcgaacagcttaaaaagcaacaggaagaagctcag
gcagttgcggcagcatcagctgcttcaagagatttcagtggaataggtgggttaggagag
ctgttggaaagttcttcagaagcatcaaagttgagttccaaaagtgctaaagaatggagg
aaccgaaggaagaaaagaagacagagagagcaccttgaaggaaacaacaaaggagagaga
gacagctttcccaaatccgaatctgaagacagcgtcaaaagaagcagcttccttttctcc
atggatggaaacagactgaccagtgacaaaaaattctgctcccctcatcagtctctcttg
agtatccgtggctccctgttttccccaagacgcaatagcaaaacaagcattttcagtttc
agaggtcgggcaaaggatgttggatctgaaaatgactttgctgatgatgaacacagcaca
tttgaagacagcgaaagcaggagagactcactgtttgtgccgcacagacatggagagcga
cgcaacagtaacgttagtcaggccagtatgtcatccaggatggtgccagggcttccagca
aatgggaagatgcacagcactgtggattgcaatggtgtggtttccttggtgggtggacct
tcagctctaacgtcacctactggacaacttcccccagagggcaccaccacagaaacggaa
gtcagaaagagaaggttaagctcttaccagatttcaatggagatgctggaggattcctct
ggaaggcaaagagccgtgagcatagccagcattctgaccaacacaatggaagaacttgaa
gaatctagacagaaatgtccgccatgctggtatagatttgccaatgtgttcttgatctgg
gactgctgtgatgcatggttaaaagtaaaacatcttgtgaatttaattgttatggatcca
tttgttgatcttgccatcactatttgcattgtcttaaataccctctttatggccatggag
cactaccccatgactgagcaattcagtagtgtgttgactgtaggaaacctggtctttact
gggattttcacagcagaaatggttctcaagatcattgccatggatccttattactatttc
caagaaggctggaatatctttgatggaattattgtcagcctcagtttaatggagcttggt
ctgtcaaatgtggagggattgtctgtactgcgatcattcagactgcttagagttttcaag
ttggcaaaatcctggcccacactaaatatgctaattaagatcattggcaattctgtgggg
gctctaggaaacctcaccttggtgttggccatcatcgtcttcatttttgctgtggtcggc
atgcagctctttggtaagagctacaaagaatgtgtctgcaagatcaatgatgactgtacg
ctcccacggtggcacatgaacgacttcttccactccttcctgattgtgttccgcgtgctg
tgtggagagtggatagagaccatgtgggactgtatggaggtcgctggccaaaccatgtgc
cttattgttttcatgttggtcatggtcattggaaaccttgtggttctgaacctctttctg
gccttattgttgagttcatttagctcagacaaccttgctgctactgatgatgacaatgaa
atgaataatctgcagattgcagtaggaagaatgcaaaagggaattgattatgtgaaaaat
aagatgcgggagtgtttccaaaaagccttttttagaaagccaaaagttatagaaatccat
gaaggcaataagatagacagctgcatgtccaataatactggaattgaaataagcaaagag
cttaattatcttagagatgggaatggaaccaccagtggtgtaggtactggaagcagtgtt
gaaaaatacgtaatcgatgaaaatgattatatgtcattcataaacaaccccagcctcacc
gtcacagtgccaattgctgttggagagtctgactttgaaaacttaaatactgaagagttc
agcagtgagtcagaactagaagaaagcaaagagaaattaaatgcaaccagctcatctgaa
ggaagcacagttgatgttgttctaccccgagaaggtgaacaagctgaaactgaacccgaa
gaagaccttaaaccggaagcttgttttactgaaggatgtattaaaaagtttccattctgt
caagtaagtacagaagaaggcaaagggaagatctggtggaatcttcgaaaaacctgctac
agtattgttgagcacaactggtttgagactttcattgtgttcatgatccttctcagtagt
ggtgcattggcctttgaagatatatacattgaacagcgaaagactatcaaaaccatgcta
gaatatgctgacaaagtctttacctatatattcattctggaaatgcttctcaaatgggtt
gcttatggatttcaaacatatttcactaatgcctggtgctggctagatttcttgatcgtt
gatgtttctttggttagcctggtagccaatgctcttggctactcagaactcggtgccatc
aaatcattacggacattaagagctttaagacctctaagagccttatcccggtttgaaggc
atgagggtggttgtgaatgctcttgttggagcaattccctctatcatgaatgtgctgttg
gtctgtctcatcttctggttgatctttagcatcatgggtgtgaatttgtttgctggcaag
ttctaccactgtgttaacatgacaacgggtaacatgtttgacattagtgatgttaacaat
ttgagtgactgtcaggctcttggcaagcaagctcggtggaaaaacgtgaaagtaaacttt
gataatgttggcgctggctatcttgcactgcttcaagtggccacatttaaaggctggatg
gatattatgtatgcagctgttgattcacgagatgttaaacttcagcctgtatatgaagaa
aatctgtacatgtatttatactttgtcatctttatcatctttgggtcattcttcactctg
aatctattcattggtgtcatcatagataacttcaaccagcagaaaaagaagtttggaggt
caagacatctttatgacagaggaacagaaaaaatattacaatgcaatgaagaaacttgga
tccaagaaacctcagaaacccatacctcgcccagcaaacaaattccaaggaatggtcttt
gattttgtaaccagacaagtctttgatatcagcatcatgatcctcatctgcctcaacatg
gtcaccatgatggtggaaacggatgaccagggcaaatacatgaccctagttttgtcccgg
atcaacctagtgttcattgttctgttcactggagaatttgtgctgaagctcgtctccctc
agacactactacttcactataggctggaacatctttgactttgtggtggtgattctctcc
attgtaggtatgtttctggctgagatgatagaaaagtattttgtgtcccctaccttgttc
cgagtgatccgtcttgccaggattggccgaatcctacgtctgatcaaaggagcaaagggg
atccgcacgctgctctttgctttgatgatgtcccttcctgcgttgtttaacatcggcctc
ctgctcttcctggtcatgtttatctatgccatctttgggatgtccaactttgcctatgtt
aaaaaggaagctggaattgatgacatgttcaactttgagacctttggcaacagcatgatc
tgcttgttccaaattacaacctctgctggctgggatggattgctagcacctattcttaat
agtgcaccacccgactgtgaccctgacacaattcaccctggcagctcagttaagggagac
tgtgggaacccatctgttgggattttcttttttgtcagttacatcatcatatccttcctg
gttgtggtgaacatgtacatcgcggtcatcctggagaacttcagtgttgctactgaagaa
agtgcagagcccctgagtgaggatgactttgagatgttctatgaggtttgggaaaagttt
gatcccgatgcgacccagtttatagagttctctaaactctctgattttgcagctgccctg
gatcctcctcttctcatagcaaaacccaacaaagtccagcttattgccatggatctgccc
atggtcagtggtgaccggatccactgtcttgatattttatttgcctttacaaagcgtgtt
ttgggtgagagtggagagatggatgcccttcgaatacagatggaagacaggtttatggca
tcaaacccctccaaagtctcttatgagcctattacaaccactttgaaacgtaaacaagag
gaggtgtctgccgctatcattcagcgtaatttcagatgttatcttttaaagcaaaggtta
aaaaatatatcaagtaactataacaaagaggcaattaaagggaggattgacttacctata
aaacaagacatgattattgacaaactaaatgggaactccactccagaaaaaacagatggg
agttcctctaccacctctcctccttcctatgatagtgtaacaaaaccagacaaggaaaag
tttgagaaagacaaaccagaaaaagaaagcaaaggaaaagaggtcagagaaaatcaaaag
taa

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