KEGG   Homo sapiens (human): 6502Help
Entry
6502              CDS       T01001                                 

Gene name
SKP2, FBL1, FBXL1, FLB1, p45
Definition
(RefSeq) S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
  KO
K03875  
F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
Organism
hsa  Homo sapiens (human)
Pathway
FoxO signaling pathway
Cell cycle
Ubiquitin mediated proteolysis
mTOR signaling pathway
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Small cell lung cancer
Module
SCF-SKP2 complex
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    6502 (SKP2)
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    6502 (SKP2)
   04150 mTOR signaling pathway
    6502 (SKP2)
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    6502 (SKP2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    6502 (SKP2)
   05203 Viral carcinogenesis
    6502 (SKP2)
   05222 Small cell lung cancer
    6502 (SKP2)
  Infectious diseases
   05168 Herpes simplex infection
    6502 (SKP2)
   05169 Epstein-Barr virus infection
    6502 (SKP2)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   SCF complex
    Target recognizing subunit (F-box)
     6502 (SKP2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
5p13
AA seq 424 aa AA seqDB search
MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
PSCL
NT seq 1275 nt NT seq  +upstreamnt  +downstreamnt
atgcacaggaagcacctccaggagattccagacctgagtagcaacgttgccaccagcttc
acgtggggatgggattccagcaagacttctgaactgctgtcaggcatgggggtctccgcc
ctggagaaagaggagcccgacagtgagaacatcccccaggaactgctctcaaacctgggc
cacccggagagccccccacggaaacggctgaagagcaaagggagtgacaaagactttgtg
attgtccgcaggcctaagctaaatcgagagaactttccaggtgtttcatgggactccctt
ccggatgagctgctcttgggaatcttttcctgtctgtgcctccctgagctgctaaaggtc
tctggtgtttgtaagaggtggtatcgcctagcgtctgatgagtctctatggcagacctta
gacctcacaggtaaaaatctgcacccggatgtgactggtcggttgctgtctcaaggggtg
attgccttccgctgcccacgatcatttatggaccaaccattggctgaacatttcagccct
tttcgtgtacagcacatggacctatcgaactcagttatagaagtgtccaccctccacggc
atactgtctcagtgttccaagttgcagaatctaagcctggaaggcctgcggctttcggat
cccattgtcaatactctcgcaaaaaactcaaatttagtgcgacttaacctttctgggtgt
tctggattctctgaatttgccctgcagactttgctaagcagctgttccagactggatgag
ctgaacctctcctggtgttttgatttcactgaaaagcatgtacaggtggctgttgcgcat
gtgtcagagaccatcacccagctgaatcttagcggctacagaaagaatctccagaaatca
gatctctctactttagttagaagatgccccaatcttgtccatctagacttaagtgatagt
gtcatgctaaagaatgactgctttcaggaatttttccagctcaactacctccaacaccta
tcactcagtcggtgctatgatataatacctgaaactttacttgaacttggagaaattccc
acactaaaaacactacaagtttttggaatcgtgccagatggtacccttcaactgttaaag
gaagcccttcctcatctacagattaattgctcccatttcaccaccattgccaggccaact
attggcaacaaaaagaaccaggagatatggggcatcaaatgccgactgacactgcaaaag
cccagttgtctatga

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