KEGG T01001: 6667

Homo sapiens (human): 6667

Entry

6667 CDS T01001

Gene name

SP1

Definition

Sp1 transcription factor

Orthology

K04684

transcription factor Sp1

Organism

hsa Homo sapiens (human)

Pathway

hsa04350	TGF-beta signaling pathway
hsa04915	Estrogen signaling pathway
hsa05016	Huntington's disease
hsa05202	Transcriptional misregulation in cancer

Drug target

Other:

D09014

Class

Environmental Information Processing; Signal transduction; TGF-beta signaling pathway [PATH:hsa04350]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:hsa04915]
Human Diseases; Cancers; Transcriptional misregulation in cancers [PATH:hsa05202]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:hsa05016]

SSDB

Motif

Pfam:

zf-H2C2_2 zf-C2H2 zf-C2H2_4 zf-Di19 RRN7 zf-C2H2_6

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

1VA1 1VA2 1VA3 1SP1 1SP2

Position

12q13.1

AA seq 737 aa
MSDQDHSMDEMTAVVKIEKGVGGNNGGNGNGGGAFSQARSSSTGSSSSTGGGGQGANGWQ
IISSSSGATPTSKEQSGSSTNGSNGSESSKNRTVSGGQYVVAAAPNLQNQQVLTGLPGVM
PNIQYQVIPQFQTVDGQQLQFAATGAQVQQDGSGQIQIIPGANQQIITNRGSGGNIIAAM
PNLLQQAVPLQGLANNVLSGQTQYVTNVPVALNGNITLLPVNSVSAATLTPSSQAVTISS
SGSQESGSQPVTSGTTISSASLVSSQASSSSFFTNANSYSTTTTTSNMGIMNFTTSGSSG
TNSQGQTPQRVSGLQGSDALNIQQNQTSGGSLQAGQQKEGEQNQQTQQQQILIQPQLVQG
GQALQALQAAPLSGQTFTTQAISQETLQNLQLQAVPNSGPIIIRTPTVGPNGQVSWQTLQ
LQNLQVQNPQAQTITLAPMQGVSLGQTSSSNTTLTPIASAASIPAGTVTVNAAQLSSMPG
LQTINLSALGTSGIQVHPIQGLPLAIANAPGDHGAQLGLHGAGGDGIHDDTAGGEEGENS
PDAQPQAGRRTRREACTCPYCKDSEGRGSGDPGKKKQHICHIQGCGKVYGKTSHLRAHLR
WHTGERPFMCTWSYCGKRFTRSDELQRHKRTHTGEKKFACPECPKRFMRSDHLSKHIKTH
QNKKGGPGVALSVGTLPLDSGAGSEGSGTATPSALITTNMVAMEAICPEGIARLANSGIN
VMQVADLQSINISGNGF

NT seq 2214 nt +upstreamnt +downstreamnt
atgagcgaccaagatcactccatggatgaaatgacagctgtggtgaaaattgaaaaagga
gttggtggcaataatgggggcaatggtaatggtggtggtgccttttcacaggctcgaagt
agcagcacaggcagtagcagcagcactggaggaggagggcagggtgccaatggctggcag
atcatctcttcctcctctggggctacccctacctcaaaggaacagagtggcagcagtacc
aatggcagcaatggcagtgagtcttccaagaatcgcacagtctctggtgggcagtatgtt
gtggctgccgctcccaacttacagaaccagcaagttctgacaggactacctggagtgatg
cctaatattcagtatcaagtaatcccacagttccagaccgttgatgggcaacagctgcag
tttgctgccactggggcccaagtgcagcaggatggttctggtcaaatacagatcatacca
ggtgcaaaccaacagattatcacaaatcgaggaagtggaggcaacatcattgctgctatg
ccaaacctactccagcaggctgtccccctccaaggcctggctaataatgtactctcagga
cagactcagtatgtgaccaatgtaccagtggccctgaatgggaacatcaccttgctacct
gtcaacagcgtttctgcagctaccttgactcccagctctcaggcagtcacgatcagcagc
tctgggtcccaggagagtggctcacagcctgtcacctcagggactaccatcagttctgcc
agcttggtatcatcacaagccagttccagctcctttttcaccaatgccaatagctactca
actactactaccaccagcaacatgggaattatgaactttactaccagtggatcatcaggg
accaactctcaaggccagacaccccagagggtcagtgggctacaggggtctgatgctctg
aacatccagcaaaaccagacatctggaggctcattgcaagcaggccagcaaaaagaagga
gagcaaaaccagcagacacagcagcaacaaattcttatccagcctcagctagttcaaggg
ggacaggccctccaggccctccaagcagcaccattgtcagggcagacctttacaactcaa
gccatctcccaggaaaccctccagaacctccagcttcaggctgttccaaactctggtccc
atcatcatccggacaccaacagtggggcccaatggacaggtcagttggcagactctacag
ctgcagaacctccaagttcagaacccacaagcccaaacaatcaccttagccccaatgcag
ggtgtttccttggggcagaccagcagcagcaacaccactctcacacccattgcctcagct
gcttccattcctgctggcacagtcactgtgaatgctgctcaactctcctccatgccaggc
ctccagaccattaacctcagtgcattgggtacttcaggaatccaggtgcacccaattcaa
ggcctgccgttggctatagcaaatgccccaggtgatcatggagctcagcttggtctccat
ggggctggtggtgatggaatacatgatgacacagcaggtggagaggaaggagaaaacagc
ccagatgcccaaccccaagccggtcggaggacccggcgggaagcatgcacctgcccctac
tgtaaagacagtgaaggaaggggctcgggggatcctggcaaaaagaaacagcatatttgc
cacatccaaggctgtgggaaagtgtatggcaagacctctcacctgcgggcacacttgcgc
tggcatacaggcgagaggccatttatgtgtacctggtcatactgtgggaaacgcttcaca
cgttcggatgagctacagaggcacaaacgtacacacacaggtgagaagaaatttgcctgc
cctgagtgtcctaagcgcttcatgaggagtgaccacctgtcaaaacatatcaagacccac
cagaataagaagggaggcccaggtgtagctctgagtgtgggcactttgcccctggacagt
ggggcaggttcagaaggcagtggcactgccactccttcagcccttattaccaccaatatg
gtagccatggaggccatctgtccagagggcattgcccgtcttgccaacagtggcatcaac
gtcatgcaggtggcagatctgcagtccattaatatcagtggcaatggcttctga

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (47)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (11)   
   UniGene (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   PRONIT (27)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (3)   
   RefSeq(pep) (3)   
DNA sequence (51)   
   RefSeq(nuc) (3)   
   GenBank (24)   
   EMBL (24)   
3D Structure (5)   
   PDB (5)   
Protein domain (6)   
   Pfam (6)   
All databases (122)   

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