KEGG T01001: 6720

Homo sapiens (human): 6720

Entry

6720 CDS T01001

Gene name

SREBF1, SREBP-1c, SREBP1, bHLHd1

Definition

sterol regulatory element binding transcription factor 1

Orthology

K07197

sterol regulatory element-binding transcription factor 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04910

Insulin signaling pathway

Class

Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:hsa04910]

SSDB

Motif

Pfam:

HLH DUF904 DUF1646

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

1AM9

Position

17p11.2

AA seq 1177 aa
MDEPPFSEAALEQALGEPCDLDAALLTDIEGEVGAGRGRANGLDAPRAGADRGAMDCTFE
DMLQLINNQDSDFPGLFDPPYAGSGAGGTDPASPDTSSPGSLSPPPATLSSSLEAFLSGP
QAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSFP
APAPPQFSSTPVLGYPSPPGGFSTGSPPGNTQQPLPGLPLASPPGVPPVSLHTQVQSVVP
QQLLTVTAAPTAAPVTTTVTSQIQQVPVLLQPHFIKADSLLLTAMKTDGATVKAAGLSPL
VSGTTVQTGPLPTLVSGGTILATVPLVVDAEKLPINRLAAGSKAPASAQSRGEKRTAHNA
IEKRYRSSINDKIIELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLSLRTA
VHKSKSLKDLVSACGSGGNTDVLMEGVKTEVEDTLTPPPSDAGSPFQSSPLSLGSRGSGS
GGSGSDSEPDSPVFEDSKAKPEQRPSLHSRGMLDRSRLALCTLVFLCLSCNPLASLLGAR
GLPSPSDTTSVYHSPGRNVLGTESRDGPGWAQWLLPPVVWLLNGLLVLVSLVLLFVYGEP
VTRPHSGPAVYFWRHRKQADLDLARGDFAQAAQQLWLALRALGRPLPTSHLDLACSLLWN
LIRHLLQRLWVGRWLAGRAGGLQQDCALRVDASASARDAALVYHKLHQLHTMGKHTGGHL
TATNLALSALNLAECAGDAVSVATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACL
AQSGSVPPAMQWLCHPVGHRFFVDGDWSVLSTPWESLYSLAGNPVDPLAQVTQLFREHLL
ERALNCVTQPNPSPGSADGDKEFSDALGYLQLLNSCSDAAGAPAYSFSISSSMATTTGVD
PVAKWWASLTAVVIHWLRRDEEAAERLCPLVEHLPRVLQESERPLPRAALHSFKAARALL
GCAKAESGPASLTICEKASGYLQDSLATTPASSSIDKAVQLFLCDLLLVVRTSLWRQQQP
PAPAPAAQGTSSRPQASALELRGFQRDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASP
TRTHQLLDRSLRRRAGPGGKGGAVAELEPRPTRREHAEALLLASCYLPPGFLSAPGQRVG
MLAEAARTLEKLGDRRLLHDCQQMLMRLGGGTTVTSS

NT seq 3534 nt +upstreamnt +downstreamnt
atggacgagccacccttcagcgaggcggctttggagcaggcgctgggcgagccgtgcgat
ctggacgcggcgctgctgaccgacatcgaaggtgaagtcggcgcggggaggggtagggcc
aacggcctggacgccccaagggcgggcgcagatcgcggagccatggattgcactttcgaa
gacatgcttcagcttatcaacaaccaagacagtgacttccctggcctatttgacccaccc
tatgctgggagtggggcagggggcacagaccctgccagccccgataccagctccccaggc
agcttgtctccacctcctgccacattgagctcctctcttgaagccttcctgagcgggccg
caggcagcgccctcacccctgtcccctccccagcctgcacccactccattgaagatgtac
ccgtccatgcccgctttctcccctgggcctggtatcaaggaagagtcagtgccactgagc
atcctgcagacccccaccccacagcccctgccaggggccctcctgccacagagcttccca
gccccagccccaccgcagttcagctccacccctgtgttaggctaccccagccctccggga
ggcttctctacaggaagccctcccgggaacacccagcagccgctgcctggcctgccactg
gcttccccgccaggggtcccgcccgtctccttgcacacccaggtccagagtgtggtcccc
cagcagctactgacagtcacagctgcccccacggcagcccctgtaacgaccactgtgacc
tcgcagatccagcaggtcccggtcctgctgcagccccacttcatcaaggcagactcgctg
cttctgacagccatgaagacagacggagccactgtgaaggcggcaggtctcagtcccctg
gtctctggcaccactgtgcagacagggcctttgccgaccctggtgagtggcggaaccatc
ttggcaacagtcccactggtcgtagatgcggagaagctgcctatcaaccggctcgcagct
ggcagcaaggccccggcctctgcccagagccgtggagagaagcgcacagcccacaacgcc
attgagaagcgctaccgctcctccatcaatgacaaaatcattgagctcaaggatctggtg
gtgggcactgaggcaaagctgaataaatctgctgtcttgcgcaaggccatcgactacatt
cgctttctgcaacacagcaaccagaaactcaagcaggagaacctaagtctgcgcactgct
gtccacaaaagcaaatctctgaaggatctggtgtcggcctgtggcagtggagggaacaca
gacgtgctcatggagggcgtgaagactgaggtggaggacacactgaccccacccccctcg
gatgctggctcacctttccagagcagccccttgtcccttggcagcaggggcagtggcagc
ggtggcagtggcagtgactcggagcctgacagcccagtctttgaggacagcaaggcaaag
ccagagcagcggccgtctctgcacagccggggcatgctggaccgctcccgcctggccctg
tgcacgctcgtcttcctctgcctgtcctgcaaccccttggcctccttgctgggggcccgg
gggcttcccagcccctcagataccaccagcgtctaccatagccctgggcgcaacgtgctg
ggcaccgagagcagagatggccctggctgggcccagtggctgctgcccccagtggtctgg
ctgctcaatgggctgttggtgctcgtctccttggtgcttctctttgtctacggtgagcca
gtcacacggccccactcaggccccgccgtgtacttctggaggcatcgcaagcaggctgac
ctggacctggcccggggagactttgcccaggctgcccagcagctgtggctggccctgcgg
gcactgggccggcccctgcccacctcccacctggacctggcttgtagcctcctctggaac
ctcatccgtcacctgctgcagcgtctctgggtgggccgctggctggcaggccgggcaggg
ggcctgcagcaggactgtgctctgcgagtggatgctagcgccagcgcccgagacgcagcc
ctggtctaccataagctgcaccagctgcacaccatggggaagcacacaggcgggcacctc
actgccaccaacctggcgctgagtgccctgaacctggcagagtgtgcaggggatgccgtg
tctgtggcgacgctggccgagatctatgtggcggctgcattgagagtgaagaccagtctc
ccacgggccttgcattttctgacacgcttcttcctgagcagtgcccgccaggcctgcctg
gcacagagtggctcagtgcctcctgccatgcagtggctctgccaccccgtgggccaccgt
ttcttcgtggatggggactggtccgtgctcagtaccccatgggagagcctgtacagcttg
gccgggaacccagtggaccccctggcccaggtgactcagctattccgggaacatctctta
gagcgagcactgaactgtgtgacccagcccaaccccagccctgggtcagctgatggggac
aaggaattctcggatgccctcgggtacctgcagctgctgaacagctgttctgatgctgcg
ggggctcctgcctacagcttctccatcagttccagcatggccaccaccaccggcgtagac
ccggtggccaagtggtgggcctctctgacagctgtggtgatccactggctgcggcgggat
gaggaggcggctgagcggctgtgcccgctggtggagcacctgccccgggtgctgcaggag
tctgagagacccctgcccagggcagctctgcactccttcaaggctgcccgggccctgctg
ggctgtgccaaggcagagtctggtccagccagcctgaccatctgtgagaaggccagtggg
tacctgcaggacagcctggctaccacaccagccagcagctccattgacaaggccgtgcag
ctgttcctgtgtgacctgcttcttgtggtgcgcaccagcctgtggcggcagcagcagccc
ccggccccggccccagcagcccagggcaccagcagcaggccccaggcttccgcccttgag
ctgcgtggcttccaacgggacctgagcagcctgaggcggctggcacagagcttccggccc
gccatgcggagggtgttcctacatgaggccacggcccggctgatggcgggggccagcccc
acacggacacaccagctcctcgaccgcagtctgaggcggcgggcaggccccggtggcaaa
ggaggcgcggtggcggagctggagccgcggcccacgcggcgggagcacgcggaggccttg
ctgctggcctcctgctacctgccccccggcttcctgtcggcgcccgggcagcgcgtgggc
atgctggctgaggcggcgcgcacactcgagaagcttggcgatcgccggctgctgcacgac
tgtcagcagatgctcatgcgcctgggcggtgggaccactgtcacttccagctag

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (17)   
   UniGene (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (40)   
   RefSeq(nuc) (2)   
   GenBank (19)   
   EMBL (19)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (76)   

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