KEGG   Homo sapiens (human): 6737
Entry
6737              CDS       T01001                                 
Symbol
TRIM21, RNF81, RO52, Ro/SSA, SSA, SSA1
Name
(RefSeq) tripartite motif containing 21
  KO
K10651  tripartite motif-containing protein 21 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    6737 (TRIM21)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    6737 (TRIM21)
   04131 Membrane trafficking [BR:hsa04131]
    6737 (TRIM21)
   04121 Ubiquitin system [BR:hsa04121]
    6737 (TRIM21)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     6737 (TRIM21)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     6737 (TRIM21)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Other autophagy associated proteins
   TRIM-directed selective autophagy
    6737 (TRIM21)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRIM/RBCC proteins
    6737 (TRIM21)
SSDB
Motif
Pfam: SPRY PRY zf-C3HC4 zf-RING_UBOX zf-C3HC4_4 zf-C3HC4_2 zf-B_box zf-RING_2 zf-C3HC4_3 zf-RING_6 zf-RING_5 zf-Nse zf-RING_4 Sina_RING zf-rbx1 zf-RING_10 U-box zf-UDP At2g31720-like zf-ANAPC11 DZR_2
Other DBs
NCBI-GeneID: 6737
NCBI-ProteinID: NP_003132
OMIM: 109092
HGNC: 11312
Ensembl: ENSG00000132109
UniProt: P19474
Structure
Position
11:complement(4384897..4393702)
AA seq 475 aa
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLL
KNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKH
RDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHA
EFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSA
LELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWL
ILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCR
DSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSF
YNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
NT seq 1428 nt   +upstreamnt  +downstreamnt
atggcttcagcagcacgcttgacaatgatgtgggaggaggtcacatgccctatctgcctg
gaccccttcgtggagcctgtgagcatcgagtgtggccacagcttctgccaggaatgcatc
tctcaggttgggaaaggtgggggcagcgtctgtcctgtgtgccggcagcgctttctgctc
aagaatctccggcccaatcgacagctagccaacatggtgaacaaccttaaagaaatcagc
caggaggccagagagggcacacagggggaacggtgtgcagtgcatggagagagacttcac
ctgttctgtgagaaagatgggaaggccctttgctgggtatgtgcccagtctcggaaacac
cgtgaccacgccatggtccctcttgaggaggctgcacaggagtaccaggagaagctccag
gtggcattaggggaactgagaagaaagcaggagttggctgagaagttggaagtggaaatt
gcaataaagagagcagactggaagaaaacagtggaaacacagaaatctaggattcacgca
gagtttgtgcagcaaaaaaacttcctggttgaagaagaacagaggcagctgcaggagctg
gagaaggatgagagggagcagctgagaatcctgggggagaaagaggccaagctggcccag
cagagccaggccctacaggagctcatctcagagctagatcgaaggtgccacagctcagca
ctggaactgctgcaggaggtgataattgtcctggaaaggagtgagtcctggaacctgaag
gacctggatattacctctccagaactcaggagtgtgtgccatgtgccagggctgaagaag
atgctgaggacatgtgcagtccacatcactctggatccagacacagccaatccgtggctg
atactttcagaagatcggagacaagtgaggcttggagacacccagcagagcatacctgga
aatgaagagagatttgatagttatcctatggtcctgggtgcccagcactttcactctgga
aaacattactgggaggtagatgtgacaggaaaggaggcctgggacctgggtgtctgcaga
gactctgtgcgcaggaaggggcactttttgcttagttccaagagtggcttctggacaatt
tggttgtggaacaaacaaaaatatgaggctggcacctacccccagactcccctccacctt
caggtgcctccatgccaagttgggattttcctggactatgaggctggcatggtctccttc
tacaacatcactgaccatggctccctcatctactccttctctgaatgtgcctttacagga
cctctgcggcccttcttcagtcctggtttcaatgatggaggaaaaaacacagcccctcta
accctctgtccactgaatattggatcacaaggatccactgactattga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (7)   
   PDB (7)   
Protein domain (21)   
   Pfam (21)   
All databases (75)   

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