KEGG T01001: 6999

Homo sapiens (human): 6999

Entry

6999 CDS T01001

Gene name

TDO2, TDO, TO, TPH2, TRPO

Definition

tryptophan 2,3-dioxygenase (EC:1.13.11.11)

Orthology

K00453

tryptophan 2,3-dioxygenase [EC:1.13.11.11]

Organism

hsa Homo sapiens (human)

Pathway

hsa00380	Tryptophan metabolism
hsa01100	Metabolic pathways

Class

Metabolism; Amino acid metabolism; Tryptophan metabolism [PATH:hsa00380]

SSDB

Motif

Pfam:

Trp_dioxygenase

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

4q31-q32

AA seq 406 aa
MSGCPFLGNNFGYTFKKLPVEGSEEDKSQTGVNRASKGGLIYGNYLHLEKVLNAQELQSE
TKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVVSRMHRVSV
ILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQNMRVPYNRRHY
RDNFKGEENELLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEKNITRGLEEEFIR
IQAKEESEEKEEQVAEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYRE
EPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGSKAGTGGSSGYHYLRSTVSDRYK
VFVDLFNLSTYLIPRHWIPKMNPTIHKFLYTAEYCDSSYFSSDESD

NT seq 1221 nt +upstreamnt +downstreamnt
atgagtgggtgcccatttttaggaaacaactttggatatacttttaaaaaactccccgta
gaaggcagcgaagaagacaaatcacaaactggtgtgaatagagccagcaaaggaggtctt
atctatgggaactacctgcatttggaaaaagttttgaatgcacaagaactgcaaagtgaa
acaaaaggaaataaaatccatgatgaacatctttttatcataactcatcaagcttatgaa
ctctggtttaagcaaatcctctgggagttggattctgttcgagagatctttcagaatggc
catgtcagagatgaaaggaacatgcttaaggttgtttctcggatgcaccgagtgtcagtg
atcctgaaactgctggtgcagcagttttccattctggagacgatgacagccttggacttc
aatgacttcagagagtacttatctccagcatcaggcttccagagtttgcaattccgacta
ttagaaaacaagataggtgttcttcagaacatgagagtcccttataacagaagacattat
cgtgataacttcaaaggagaagaaaatgaactgctacttaaatctgagcaggaaaagaca
cttctggaattagtggaggcatggctggaaagaactccaggtttagagccacatggattt
aacttctggggaaagcttgaaaaaaatatcaccagaggcctggaagaggaattcataagg
attcaggctaaagaagagtctgaagaaaaagaggaacaggtggctgaatttcagaagcaa
aaagaggtgctactgtccttatttgatgagaaacgtcatgaacatctccttagtaaaggt
gaaagacggctgtcatacagagcacttcagggagcattgatgatatatttttacagggaa
gagcctaggttccaggtgccttttcagttgctgacttctcttatggacatagattcactg
atgaccaaatggagatataaccatgtgtgcatggtgcacagaatgctgggcagcaaagct
ggcaccggtggttcctcaggctatcactacctgcgatcaactgtgagtgataggtacaag
gtatttgtagatttatttaatctttcaacatacctgattccccgacactggataccgaag
atgaacccaaccattcacaaatttctatatacagcagaatactgtgatagctcctacttc
agcagtgatgaatcagattaa

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UniGene (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (1)   
   Pfam (1)   
All databases (49)   

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