KEGG   Homo sapiens (human): 7365
Entry
7365              CDS       T01001                                 
Symbol
UGT2B10, UDPGT2B10
Name
(RefSeq) UDP glucuronosyltransferase family 2 member B10
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00040  Pentose and glucuronate interconversions
hsa00053  Ascorbate and aldarate metabolism
hsa00140  Steroid hormone biosynthesis
hsa00830  Retinol metabolism
hsa00860  Porphyrin metabolism
hsa00980  Metabolism of xenobiotics by cytochrome P450
hsa00982  Drug metabolism - cytochrome P450
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa01240  Biosynthesis of cofactors
hsa04976  Bile secretion
hsa05204  Chemical carcinogenesis - DNA adducts
hsa05207  Chemical carcinogenesis - receptor activation
Module
hsa_M00014  Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    7365 (UGT2B10)
   00053 Ascorbate and aldarate metabolism
    7365 (UGT2B10)
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    7365 (UGT2B10)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    7365 (UGT2B10)
   00860 Porphyrin metabolism
    7365 (UGT2B10)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    7365 (UGT2B10)
   00982 Drug metabolism - cytochrome P450
    7365 (UGT2B10)
   00983 Drug metabolism - other enzymes
    7365 (UGT2B10)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    7365 (UGT2B10)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    7365 (UGT2B10)
   05207 Chemical carcinogenesis - receptor activation
    7365 (UGT2B10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    7365 (UGT2B10)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     7365 (UGT2B10)
Glycosyltransferases [BR:hsa01003]
 Others
  Hydrophobic molecule
   7365 (UGT2B10)
SSDB
Motif
Pfam: UDPGT EryCIII-like_C Glyco_tran_28_C Glyco_transf_4 SKA2
Other DBs
NCBI-GeneID: 7365
NCBI-ProteinID: NP_001066
OMIM: 600070
HGNC: 12544
Ensembl: ENSG00000109181
UniProt: P36537
Structure
Position
4:68815994..68832023
AA seq 528 aa
MALKWTTVLLIQLSFYFSSGSCGKVLVWAAEYSLWMNMKTILKELVQRGHEVTVLASSAS
ILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLSEIQKDTFWLPFSQEQEILWAIND
IIRNFCKDVVSNKKLMKKLQESRFDIVFADAYLPCGELLAELFNIPFVYSHSFSPGYSFE
RHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLYFDFWFQIFNMKKWDQFYSEVLG
RPTTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGE
NGVVVFSLGSMVSNMTEERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQND
LLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRVDFNTMS
STDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAH
NLTWFQYHSLDVIGFLLACVATVLFIITKCCLFCFWKFARKGKKGKRD
NT seq 1587 nt   +upstreamnt  +downstreamnt
atggctctgaaatggactacagttctgctgatacaactcagtttttactttagctctggg
agttgtggaaaggtgctggtatgggccgcagaatacagcctttggatgaatatgaagaca
atcctgaaagaacttgttcagagaggtcatgaggtgactgtactggcatcttcagcttcc
attctttttgatcccaacgactcatccactcttaaacttgaagtttatcctacatcttta
actaaaactgaatttgagaatatcatcatgcaattggttaagagattgtcagaaattcaa
aaagatacattttggttacctttttcacaagaacaagaaatcctgtgggcaattaatgac
ataattagaaacttctgtaaagatgtagtttcaaataagaaacttatgaaaaaactacaa
gagtcaagatttgacatcgtttttgcagatgcttatttaccctgtggtgagctgctggct
gagctatttaacataccctttgtgtacagtcacagcttcagtcctggctactcatttgaa
aggcacagtggaggatttattttccctccttcctacgtacctgttgttatgtcaaaatta
agtgatcaaatgactttcatggagagggtaaaaaatatgctctatgtgctttattttgac
ttttggttccaaatatttaatatgaagaagtgggatcagttttacagtgaagttttagga
agacccactacattatctgagacaatgaggaaagctgacatatggcttatgcgaaactcc
tggaattttaaatttcctcatccattcttaccaaatgttgattttgttggaggactccac
tgcaaacctgccaaacccctacctaaggaaatggaggagtttgtacagagctctggagaa
aatggtgttgtggtgttttctctggggtcaatggtcagtaacatgacagaagaaagggcc
aacgtaattgcaacagcccttgccaagatcccacaaaaggttctttggagatttgatggg
aataaaccagatgccttaggtctcaatactcgactgtacaagtggataccccagaatgac
cttctaggtcatccaaaaaccagagcttttataactcatggtggagccaatggcatctat
gaggcaatctaccatgggatccctatggtgggcattccattgttttttgatcaacctgat
aatattgctcacatgaaggccaagggagcagctgttagagtggacttcaacacaatgtcg
agtacagacctgctgaatgcactgaagacagtaattaatgatccttcatataaagagaat
attatgaaattatcaagaattcaacatgatcaaccagtgaagcccctggatcgagcagtc
ttctggattgaatttgtcatgcgccacaaaggagccaaacatcttcgagttgcagcccac
aacctcacctggttccagtaccactctttggatgtgattgggttcctgctggcttgtgtg
gcaaccgtgctatttatcatcacaaagtgttgtctgttttgtttctggaagtttgctaga
aaaggaaagaagggaaaaagggattag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (15)   
   KEGG PATHWAY (13)   
   KEGG MODULE (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (40)   
   KEGG COMPOUND (40)   
Chemical reaction (21)   
   KEGG ENZYME (1)   
   KEGG REACTION (20)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (19)   
   RefSeq(nuc) (7)   
   GenBank (6)   
   EMBL (6)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (131)   

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