KEGG   Homo sapiens (human): 79154
Entry
79154             CDS       T01001                                 
Symbol
DHRS11, ARPG836, SDR24C1, spDHRS11
Name
(RefSeq) dehydrogenase/reductase 11
  KO
K22970  17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00140  Steroid hormone biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    79154 (DHRS11)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     79154 (DHRS11)
    1.1.1.270  3beta-hydroxysteroid 3-dehydrogenase
     79154 (DHRS11)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR Epimerase GDP_Man_Dehyd NAD_binding_10 NmrA F420_oxidored RmlD_sub_bind Shikimate_DH Sacchrp_dh_NADP Guanylin DUF4454 NYAP_N
Other DBs
NCBI-GeneID: 79154
NCBI-ProteinID: NP_077284
OMIM: 616159
HGNC: 28639
Ensembl: ENSG00000278535
UniProt: Q6UWP2
Structure
Position
17:36591879..36600804
AA seq 260 aa
MARPGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGY
PGTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNV
NVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGL
RQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVL
STPAHIQIGDIQMRPTEQVT
NT seq 783 nt   +upstreamnt  +downstreamnt
atggccaggcccggcatggagcggtggcgcgaccggctggcgctggtgacgggggcctcg
gggggcatcggcgcggccgtggcccgggccctggtccagcagggactgaaggtggtgggc
tgcgcccgcactgtgggcaacatcgaggagctggctgctgaatgtaagagtgcaggctac
cccgggactttgatcccctacagatgtgacctatcaaatgaagaggacatcctctccatg
ttctcagctatccgttctcagcacagcggtgtagacatctgcatcaacaatgctggcttg
gcccggcctgacaccctgctctcaggcagcaccagtggttggaaggacatgttcaatgtg
aacgtgctggccctcagcatctgcacacgggaagcctaccagtccatgaaggagcggaat
gtggacgatgggcacatcattaacatcaatagcatgtctggccaccgagtgttacccctg
tctgtgacccacttctatagtgccaccaagtatgccgtcactgcgctgacagagggactg
aggcaagagcttcgggaggcccagacccacatccgagccacgtgcatctctccaggtgtg
gtggagacacaattcgccttcaaactccacgacaaggaccctgagaaggcagctgccacc
tatgagcaaatgaagtgtctcaaacccgaggatgtggccgaggctgttatctacgtcctc
agcacccccgcacacatccagattggagacatccagatgaggcccacggagcaggtgacc
tag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (28)   
   RefSeq(nuc) (10)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (14)   
   Pfam (14)   
All databases (81)   

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