KEGG T01001: 8398

Homo sapiens (human): 8398

Entry

8398 CDS T01001

Gene name

PLA2G6, CaI-PLA2, GVI, INAD1, IPLA2-VIA, NBIA2, NBIA2A, NBIA2B, PARK14, PLA2, PNPLA9, iPLA2, iPLA2beta

Definition

phospholipase A2, group VI (cytosolic, calcium-independent) (EC:3.1.1.4)

Orthology

K16343

calcium-independent phospholipase A2 [EC:3.1.1.4]

Organism

hsa Homo sapiens (human)

Pathway

hsa00564	Glycerophospholipid metabolism
hsa00565	Ether lipid metabolism
hsa00590	Arachidonic acid metabolism
hsa00591	Linoleic acid metabolism
hsa00592	alpha-Linolenic acid metabolism
hsa01100	Metabolic pathways
hsa04270	Vascular smooth muscle contraction
hsa04666	Fc gamma R-mediated phagocytosis

Disease

H00057	Parkinson's disease (PD)
H00833	Neurodegeneration with brain iron accumulation (NBIA)

Class

Metabolism; Lipid metabolism; Glycerophospholipid metabolism [PATH:hsa00564]
Metabolism; Lipid metabolism; Ether lipid metabolism [PATH:hsa00565]
Metabolism; Lipid metabolism; Arachidonic acid metabolism [PATH:hsa00590]
Metabolism; Lipid metabolism; Linoleic acid metabolism [PATH:hsa00591]
Metabolism; Lipid metabolism; alpha-Linolenic acid metabolism [PATH:hsa00592]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:hsa04666]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:hsa04270]

SSDB

Motif

Pfam:

Ank_2 Ank Ank_4 Ank_5 Ank_3 Patatin

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

22q13.1

AA seq 752 aa
MQFFGRLVNTFSGVTNLFSNPFRVKEVAVADYTSSDRVREEGQLILFQNTPNRTWDCVLV
NPRNSQSGFRLFQLELEADALVNFHQYSSQLLPFYESSPQVLHTEVLQHLTDLIRNHPSW
SVAHLAVELGIRECFHHSRIISCANCAENEEGCTPLHLACRKGDGEILVELVQYCHTQMD
VTDYKGETVFHYAVQGDNSQVLQLLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLL
LCNARCNIMGPNGYPIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAKNAEMA
RMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSK
DNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGRQLQDLMHISRARKPAFILGSMRDEK
RTHDHLLCLDGGGVKGLIIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSM
AYMRGMYFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVRKPKVMLTGTLSDRQPA
ELHLFRNYDAPETVREPRFNQNVNLRPPAQPSDQLVWRAARSSGAAPTYFRPNGRFLDGG
LLANNPTLDAMTEIHEYNQDLIRKGQANKVKKLSIVVSLGTGRSPQVPVTCVDVFRPSNP
WELAKTVFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGTDIMLDEVS
DTVLVNALWETEVYIYEHREEFQKLIQLLLSP

NT seq 2259 nt +upstreamnt +downstreamnt
atgcagttctttggccgcctggtcaataccttcagtggcgtcaccaacttgttctctaac
ccattccgggtgaaggaggtggctgtggccgactacacctcgagtgaccgagttcgggag
gaagggcagctgattctgttccagaacactcccaaccgcacctgggactgcgtcctggtc
aaccccaggaactcacagagtggattccgactcttccagctggagttggaggctgacgcc
ctagtgaatttccatcagtattcttcccagctgctacccttctatgagagctcccctcag
gtcctgcacactgaggtcctgcagcacctgaccgacctcatccgtaaccaccccagctgg
tcagtggcccacctggctgtggagctagggatccgcgagtgcttccatcacagccgtatc
atcagctgtgccaattgcgcggagaacgaggagggctgcacacccctgcacctggcctgc
cgcaagggtgatggggagatcctggtggagctggtgcagtactgccacactcagatggat
gtcaccgactacaagggagagaccgtcttccattatgctgtccagggtgacaattctcag
gtgctgcagctccttggaaggaacgcagtggctggcctgaaccaggtgaataaccaaggg
ctgaccccgctgcacctggcctgccagctggggaagcaggagatggtccgcgtgctgctg
ctgtgcaatgctcggtgcaacatcatgggccccaacggctaccccatccactcggccatg
aagttctctcagaaggggtgtgcggagatgatcatcagcatggacagcagccagatccac
agcaaagacccccgttacggagccagccccctccactgggccaagaacgcagagatggcc
cgcatgctgctgaaacggggctgcaacgtgaacagcaccagctccgcggggaacacggcc
ctgcacgtggcggtgatgcgcaaccgcttcgactgtgccatagtgctgctgacccacggg
gccaacgcggatgcccgcggagagcacggcaacaccccgctgcacctggccatgtcgaaa
gacaacgtggagatgatcaaggccctcatcgtgttcggagcagaagtggacaccccgaat
gactttggggagactcctacattcctagcctccaaaatcggcagacaactacaggatctc
atgcacatctcacgggcccggaagccagcgttcatcctgggctccatgagggacgagaag
cggacccacgaccacctgctgtgcctggatggaggaggagtgaaaggcctcatcatcatc
cagctcctcatcgccatcgagaaggcctcgggtgtggccaccaaggacctgtttgactgg
gtggcgggcaccagcactggaggcatcctggccctggccattctgcacagtaagtccatg
gcctacatgcgcggcatgtactttcgcatgaaggatgaggtgttccggggctccaggccc
tacgagtcggggcccctggaggagttcctgaagcgggagtttggggagcacaccaagatg
acggacgtcaggaaacccaaggtgatgctgacagggacactgtctgaccggcagccggct
gaactccacctcttccggaactacgatgctccagaaactgtccgggagcctcgtttcaac
cagaacgttaacctcaggcctccagctcagccctcagaccagctggtgtggcgggcggcc
cgaagcagcggggcagctcctacttacttccgacccaatgggcgcttcctggacggtggg
ctgctggccaacaaccccacgctggatgccatgaccgagatccatgagtacaatcaggac
ctgatccgcaagggtcaggccaacaaggtgaagaaactctccatcgttgtctccctgggg
acagggaggtccccacaagtgcctgtgacctgtgtggatgtcttccgtcccagcaacccc
tgggagctggccaagactgtttttggggccaaggaactgggcaagatggtggtggactgt
tgcacggatccagacgggcgggctgtggaccgggcacgggcctggtgcgagatggtcggc
atccagtacttcagattgaacccccagctggggacggacatcatgctggatgaggtcagt
gacacagtgctggtcaacgccctctgggagaccgaggtctacatctatgagcaccgcgag
gagttccagaagctcatccagctgctgctctcaccctga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Disease (6)   
   KEGG DISEASE (2)   
   OMIM (4)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (14)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (2)   
   RefSeq(pep) (3)   
DNA sequence (37)   
   RefSeq(nuc) (3)   
   GenBank (17)   
   EMBL (17)   
Protein domain (6)   
   Pfam (6)   
All databases (108)   

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