KEGG   Homo sapiens (human): 84447
Entry
84447             CDS       T01001                                 
Symbol
SYVN1, DER3, HRD1
Name
(RefSeq) synoviolin 1
  KO
K10601  E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04120  Ubiquitin mediated proteolysis
hsa04141  Protein processing in endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    84447 (SYVN1)
   04120 Ubiquitin mediated proteolysis
    84447 (SYVN1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    84447 (SYVN1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     84447 (SYVN1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    84447 (SYVN1)
SSDB
Motif
Pfam: zf-RING_2 zf-C3HC4 zf-rbx1 zf-C3HC4_2 zf-RING_UBOX zf-C3HC4_3 zf-RING_16 zf-RING_11 zf-RING_5 zf-RING-like zf-ANAPC11 zf-HC5HC2H zf-C3H2C3 zf-Nse Endonuclease_7 Prok-RING_4
Other DBs
NCBI-GeneID: 84447
NCBI-ProteinID: NP_757385
OMIM: 608046
HGNC: 20738
Ensembl: ENSG00000162298
UniProt: Q86TM6
Structure
Position
11:complement(65127279..65134519)
AA seq 617 aa
MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI
LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGA
ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG
FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV
NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA
AELRRRRLQKLESPVAH
NT seq 1854 nt   +upstreamnt  +downstreamnt
atgttccgcacggcagtgatgatggcggccagcctggcgctgaccggggctgtggtggct
cacgcctactacctcaaacaccagttctaccccactgtggtgtacctgaccaagtccagc
cccagcatggcagtcctgtacatccaggcctttgtccttgtcttccttctgggcaaggtg
atgggcaaggtgttctttgggcaactgagggcagcagagatggagcaccttctggaacgt
tcctggtacgccgtcacagagacttgtctggccttcaccgtttttcgggatgacttcagc
ccccgctttgttgcactcttcactcttcttctcttcctcaaatgtttccactggctggct
gaggaccgtgtggactttatggaacgcagccccaacatctcctggctctttcactgccgc
attgtctctcttatgttcctcctgggcatcctggacttcctcttcgtcagccacgcctat
cacagcatcctgacccgtggggcctctgtgcagctggtgtttggctttgagtatgccatc
ctgatgacgatggtgctcaccatcttcatcaagtatgtgctgcactccgtggacctccag
agtgagaacccctgggacaacaaggctgtgtacatgctctacacagagctgtttacaggc
ttcatcaaggttctgctgtacatggccttcatgaccatcatgatcaaggtgcacaccttc
ccactctttgccatccggcccatgtacctggccatgagacagttcaagaaagctgtgaca
gatgccatcatgtctcgccgagccatccgcaacatgaacaccctgtatccagatgccacc
ccagaggagctccaggcaatggacaatgtctgcatcatctgccgagaagagatggtgact
ggtgccaagagactgccctgcaaccacattttccataccagctgcctgcgctcctggttc
cagcggcagcagacctgccccacctgccgtatggatgtccttcgtgcatcgctgccagcg
cagtcaccaccacccccggagcctgcggatcaggggccaccccctgccccccacccccca
ccactcttgcctcagccccccaacttcccccagggcctcctgcctccttttcctccaggc
atgttcccactgtggccccccatgggcccctttccacctgtcccgcctccccccagctca
ggagaggctgtggctcctccatccaccagtgcagcagccctttctcggcccagtggagca
gctacaaccacagctgctggcaccagtgctactgctgcttctgccacagcatctggccca
ggctctggctctgccccagaggctggccctgcccctggtttccccttccctcctccctgg
atgggtatgcccctgcctccaccctttgccttccccccaatgcctgtgccccctgcgggc
tttgctgggctgaccccagaggagctacgagctctggagggccatgagcggcagcacctg
gaggcccggctgcagagcctgcgtaacatccacacactgctggacgccgccatgctgcag
atcaaccagtacctcaccgtgctggcctccttggggcccccccggcctgccacttcagtc
aactccactgaggagactgccactacagttgttgctgctgcctcctccaccagcatccct
agctcagaggccacgaccccaaccccaggagcctccccaccagcccctgaaatggaaagg
cctccagctcctgagtcagtgggcacagaggagatgcctgaggatggagagcccgatgca
gcagagctccgccggcgccgcctgcagaagctggagtctcctgttgcccactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (41)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (32)   
   RefSeq(nuc) (10)   
   GenBank (11)   
   EMBL (11)   
3D Structure (1)   
   PDB (1)   
Protein domain (16)   
   Pfam (16)   
All databases (110)   

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