KEGG   Homo sapiens (human): 8449
Entry
8449              CDS       T01001                                 
Symbol
DHX16, DBP2, DDX16, NMOAS, PRO2014, PRP8, PRPF2, Prp2
Name
(RefSeq) DEAH-box helicase 16
  KO
K12813  pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:5.6.2.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    8449 (DHX16)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    8449 (DHX16)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.6  RNA 3'-5' helicase
     8449 (DHX16)
Spliceosome [BR:hsa03041]
 Complex B
  U4/U6.U5 tri-snRNP components
   U4/U6.U5 tri-snRNP related factors
    8449 (DHX16)
 Complex C
   U4/U6.U5 tri-SnRNP related factors
    8449 (DHX16)
SSDB
Motif
Pfam: OB_NTP_bind Helicase_C HA2_C DEAD HA2_N AAA_22 AAA_19 AAA_30 SecA_DEAD nSTAND3 SRP54 Flavi_DEAD
Other DBs
NCBI-GeneID: 8449
NCBI-ProteinID: NP_003578
OMIM: 603405
HGNC: 2739
Ensembl: ENSG00000204560
UniProt: O60231 Q5SQH4
Structure
Position
6:complement(30653127..30673006)
AA seq 1041 aa
MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPAR
DFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQK
KRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDA
FAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKRER
EKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHM
PKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE
ETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLII
EGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYS
IRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVA
RFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVL
QIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIF
QPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASAN
QRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDF
LDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEI
LTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYE
NFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYR
TVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKE
LEDPHAKKMPKKIGKTREELG
NT seq 3126 nt   +upstreamnt  +downstreamnt
atggcgacgccggcgggtctggagcgctgggttcaggacgagctgcactcggtgttgggg
ctgagcgagcggcacgtcgcccagtttctgatcggtaccgcacagcgctgcacctctgcc
gaggagttcgtgcagcgcctacgagacactgataccttggatctcagtgggccggcccgg
gacttcgccctgagactctggaacaaggtaccacgaaaggcagtggtagaaaagccagct
cgggcagcagagcgagaggcccgggccctgctggagaagaaccgatcttataggttactg
gaagacagtgaagagagcagtgaggagactgtgagtagggctggaagcagcctccagaag
aaacgtaaaaagcggaaacacctcaggaagaagcgtgaggaagaagaggaggaagaggct
tctgagaaagggaagaagaaaacaggggggagtaaacagcagacagagaagccagagtcg
gaagatgagtgggaacggacagagcgtgaacgccttcaggacctggaggagcgtgatgcc
tttgctgagcgggttcgacagcgggacaaggatcggactcgaaatgtcctggaacggtca
gacaagaaggcttatgaagaggctcagaagcgcctcaagatggccgaggaagaccggaag
gccatggtccctgagctgcggaagaaatctcgccgagagtacctggctaagcgggagcga
gagaagcttgaggacctggaggcggagctggctgatgaggagttcctttttggggacgtg
gagctgagccggcacgagcggcaggagctcaaatataagcggcgagtgcgggatctcgcc
cgggagtaccgggcagctggggagcaggagaagctggaggccaccaatcgctaccacatg
cccaaggaaacccgaggacagccagcccgagctgtggatctagtggaggaggaatcagga
gcccctggggaggagcagcggcgctgggaggaggcgcggcttggggcagcgtccctgaag
tttggggcccgagatgctgcctctcaggagcccaagtatcaactggtgctggaggaggag
gagaccattgagtttgtccgggccactcagctccagggtgatgaggagccgtcagctcca
cccacttcaactcaggcccagcagaaagagtccatccaggccgtccgccgcagcctcccg
gtgttcccatttcgagaggagctcctggctgctattgcaaatcaccaagtcctcatcatt
gaaggcgagacaggctcagggaagaccacccagatcccgcagtatctctttgaggagggt
tatacaaacaagggtatgaagattgcctgcacccaaccccggagagtggctgccatgagt
gtggccgcccgagtggcccgggagatgggtgtgaagcttgggaatgaggttggctacagc
atccgctttgaggactgcacatcagagcgaactgtcctccgctacatgacagatgggatg
cttctccgggagttcctctctgagcctgacctggcgagttacagcgtggtgatggtggat
gaggcacacgaaaggaccctacacacagacattctctttggattgatcaaggatgttgct
cgcttccgacctgagctcaaggtcctggtggcttcagccacaatggacactgcccgtttt
tccaccttctttgatgacgcccctgtgtttcgaatccccggacgcaggtttcctgtggac
atcttctacaccaaggctccagaggctgactacttggaagcttgtgtagtatctgtgttg
cagatccatgtgacccagccccctggggatatcctggtgttcctgacaggacaggaggag
attgaggctgcctgtgagatgctccaggatcgctgccgccgcctgggctccaaaatccgg
gagctcctggtgctgcccatttatgccaatctgccctctgacatgcaggcccgtatcttc
cagcccacaccacctggggcacgaaaggtggttgtggcaacgaacattgctgagacatca
ctcaccattgagggcatcatttatgtgctggatccagggttctgtaagcagaagagctac
aacccccgcacaggcatggaatcgctcactgtcacaccctgcagcaaggcctcagccaat
cagcgagctggcagggcaggtcgggtggctgcagggaagtgcttccgcctgtataccgcc
tgggcctatcagcacgagcttgaggaaaccacagtgcctgagatccagaggaccagcttg
ggcaatgtcgtgttgctgctcaagagcttagggatccatgacctaatgcactttgatttc
ctggaccctccaccatatgagacactgctgctggctttggagcagctgtatgctctggga
gccctcaaccaccttggggagctcaccacgtctggtcgaaagatggcagagctgccggtg
gaccccatgctgtccaaaatgatcttagcctctgagaagtacagctgttcagaggagatc
ctgacagtggctgccatgctctctgtcaacaactccatcttctaccgaccaaaggacaag
gtcgtccatgctgacaatgcccgtgtcaacttctttctccctggcggtgaccacctggtt
ctgctaaatgtttacacacagtgggctgagagtggttactcttcccagtggtgctatgag
aactttgtacagttcagatcgatgcgccgagcccgggatgtgcgggaacagctggaaggg
ctcttggaacgtgtggaagttggtctcagttcctgccagggggactatatccgtgtacgc
aaggccatcactgctggttacttttaccacacggcacggttgactcggagtggctaccgc
acagtgaaacagcagcagacagtcttcattcatcccaactcctccctctttgagcaacag
ccacgctggctgctctaccacgaacttgtcttgaccaccaaagagttcatgagacaggta
ctggagattgagagcagttggcttctggaggtggctccccattattataaggccaaggag
ctagaagatccccatgctaagaaaatgcccaaaaaaataggcaaaacacgagaagagcta
gggtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (2)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (30)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (27)   
DNA sequence (45)   
   RefSeq(nuc) (27)   
   GenBank (9)   
   EMBL (9)   
3D Structure (7)   
   PDB (7)   
Protein domain (12)   
   Pfam (12)   
All databases (121)   

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