| Entry |
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| Symbol |
MAP1LC3A, ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3
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| Name |
(RefSeq) microtubule associated protein 1 light chain 3 alpha
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| KO |
| K10435 | microtubule-associated protein 1 light chain |
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| Organism |
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| Pathway |
| hsa04621 | NOD-like receptor signaling pathway |
| hsa05022 | Pathways of neurodegeneration - multiple diseases |
| hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
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| Network |
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| Element |
| N00156 | Autophagy-vesicle nucleation/elongation/maturation, LC3-II formation |
| N01137 | PINK-Parkin-mediated autophagosome formation |
| N01139 | Mutation-inactivated p62 to PINK-Parkin-mediated autophagosome formation |
| N01140 | TBK1-mediated autophagosome formation |
| N01141 | Mutation-inactivated TBK1 to TBK1-mediated autophagosome formation |
| N01716 | Autophagy-vesicle nucleation/elongation/maturation, sequestosome-1-like receptor |
| N01721 | Autophagosome and lysosome fusion, tethering factor |
| N01722 | Autophagosome and lysosome fusion, tethering factor, GRASP55 |
| N01756 | PINK-Parkin-independent ubiquitin-mediated mitophagy |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
84557 (MAP1LC3A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
84557 (MAP1LC3A)
04137 Mitophagy - animal
84557 (MAP1LC3A)
09143 Cell growth and death
04216 Ferroptosis
84557 (MAP1LC3A)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
84557 (MAP1LC3A)
09160 Human Diseases
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
84557 (MAP1LC3A)
09171 Infectious disease: bacterial
05131 Shigellosis
84557 (MAP1LC3A)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
84557 (MAP1LC3A)
05022 Pathways of neurodegeneration - multiple diseases
84557 (MAP1LC3A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
84557 (MAP1LC3A)
03029 Mitochondrial biogenesis [BR:hsa03029]
84557 (MAP1LC3A)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:hsa04812]
84557 (MAP1LC3A)
Membrane trafficking [BR:hsa04131]
Autophagy
Mitophagy
Other mitophagy associated proteins
84557 (MAP1LC3A)
Mitochondrial biogenesis [BR:hsa03029]
Mitochondrial quality control factors
Mitophagy factors
Other mitophagy factors
84557 (MAP1LC3A)
Cytoskeleton proteins [BR:hsa04812]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
Microtubule-associated proteins (MAPs)
84557 (MAP1LC3A)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
20:34546844..34560345
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| AA seq |
121 aa
MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
SELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFG
F |
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| NT seq |
366 nt +upstreamnt +downstreamnt
atgccctcagaccggcctttcaagcagcggcggagcttcgccgaccgctgtaaggaggta
cagcagatccgcgaccagcaccccagcaaaatcccggtgatcatcgagcgctacaagggt
gagaagcagctgcccgtcctggacaagaccaagtttttggtcccggaccatgtcaacatg
agcgagttggtcaagatcatccggcgccgcctgcagctgaaccccacgcaggccttcttc
ctgctggtgaaccagcacagcatggtgagtgtgtccacgcccatcgcggacatctacgag
caggagaaagacgaggacggcttcctctatatggtctacgcctcccaggaaaccttcggc
ttctga |
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