KEGG   Homo sapiens (human): 84617Help
Entry
84617             CDS       T01001                                 

Gene name
TUBB6, FPVEPD, HsT1601, TUBB-5
Definition
(RefSeq) tubulin beta 6 class V
  KO
K07375  tubulin beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04540  Gap junction
hsa05130  Pathogenic Escherichia coli infection
Drug target
Batabulin (DG01412): D03059 D06560
Brentuximab vedotin: D09587
Cabazitaxel (DG00695): D09755 D10452
Colchicine: D00570
Docetaxel (DG00694): D02165 D07866
Eribulin: D08914
Estramustine (DG00724): D02398 D04066 D06397
Glembatumumab vedotin: D09912
Indibulin: D10013
Lexibulin: D10073
Maytansine: D04864
Paclitaxel: D00491
Paclitaxel poliglumex: D05333
Podophyllotoxin: D05529
Soblidotin: D01919
Taltobulin: D06001
Trastuzumab emtansine: D09980
Verubulin (DG01411): D10029 D10030
Vinblastine (DG00689): D01068 D08675
Vincristine (DG00690): D02197 D08679
Vindesine (DG00691): D01769 D06304
Vinepidine sulfate: D06305
Vinflunine: D09032
Vinglycinate sulfate: D06306
Vinleurosine sulfate: D06307
Vinorelbine (DG00692): D01935 D08680
Vinrosidine sulfate: D06308
Vintafolide: D10434
Vinzolidine sulfate: D06309
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    84617 (TUBB6)
  Cellular community - eukaryotes
   04540 Gap junction
    84617 (TUBB6)
 Human Diseases
  Infectious diseases
   05130 Pathogenic Escherichia coli infection
    84617 (TUBB6)
Chromosome [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Microtubules and associated factors
    Other tubulins
     84617 (TUBB6)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    84617 (TUBB6)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   84617 (TUBB6)
  Exosomal proteins of colorectal cancer cells
   84617 (TUBB6)
  Exosomal proteins of bladder cancer cells
   84617 (TUBB6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Tubulin Tubulin_C Misat_Tub_SegII Tubulin_3 Tubulin_2
Motif
Other DBs
NCBI-GeneID: 84617
NCBI-ProteinID: NP_001290453
OMIM: 615103
HGNC: 20776
Ensembl: ENSG00000176014
Vega: OTTHUMG00000131692
Pharos: Q9BUF5(Tclin)
UniProt: Q9BUF5
Position
18p11.21
AA seq 446 aa AA seqDB search
MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATANDGEEAFEDEEEEIDG
NT seq 1341 nt NT seq  +upstreamnt  +downstreamnt
atgagggagatcgtgcacatccaggcgggccagtgcgggaaccagatcggcaccaagttt
tgggaagtgatcagcgatgagcacggcatcgacccggccggaggctacgtgggagactcg
gcgctgcagctggagagaatcaacgtctactacaatgagtcatcgtctcagaaatatgtg
cccagggccgccctggtggacttagagccaggcaccatggacagcgtgcggtctgggcct
tttgggcagcttttccggcctgacaacttcatctttggccagacgggtgcagggaacaac
tgggcgaaagggcactacacggagggcgcggagctggtggacgcagtgctggacgtggtg
cggaaggagtgcgagcactgcgactgcctgcagggcttccagctcacgcactcgctgggc
ggcggcacgggctcaggcatgggcacgctgctcatcagcaagatccgtgaggagttcccg
gaccgcatcatgaacaccttcagcgtcatgccctcgcccaaggtgtcggacacggtggtg
gagccctacaatgccacactgtcggtgcaccagctggtggagaatacagacgagacctac
tgcatcgacaacgaggcgctctatgacatctgcttccgcactctgaagctgacaacgccc
acctacggggacctcaaccacctggtgtccgccaccatgagtggggtcaccacctcgctg
cgcttcccgggccagctcaatgctgacctgcgcaagctggcggtgaacatggtgcccttc
ccgcgcctgcacttcttcatgcctggcttcgcgccgctcaccagccgcggcagccagcag
taccgggccctgaccgtgcccgagctcacccagcagatgttcgacgccaggaacatgatg
gccgcctgcgatccgcgccatggccgctacctgaccgtggccaccgtgttccgcgggccc
atgtccatgaaggaggtggacgagcagatgctggccatccagagtaagaacagcagctac
ttcgtggagtggattcccaacaacgtgaaggtggccgtgtgcgacatcccgccccgcggc
ctgaagatggcctccaccttcatcggcaacagcacggccatccaggagctgttcaagcgc
atctccgagcagttctcagccatgttccggcgcaaggccttcctgcactggttcacgggt
gagggcatggatgaaatggagttcaccgaggcggagagcaacatgaacgacctggtatcc
gagtaccagcagtaccaggatgccaccgccaatgacggggaggaagcttttgaggatgag
gaagaggagatcgatggatag

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