KEGG T01001: 8704

Homo sapiens (human): 8704

Entry

8704              CDS       T01001

Symbol

B4GALT2, B4Gal-T2, B4Gal-T3, beta4Gal-T2

Name

(RefSeq) beta-1,4-galactosyltransferase 2

K07967

beta-1,4-galactosyltransferase 2 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]

Organism

hsa Homo sapiens (human)

Pathway

hsa00052

Galactose metabolism

hsa00510

N-Glycan biosynthesis

hsa00513

Various types of N-glycan biosynthesis

hsa00514

Other types of O-glycan biosynthesis

hsa00515

Mannose type O-glycan biosynthesis

hsa00533

Glycosaminoglycan biosynthesis - keratan sulfate

hsa00601

Glycosphingolipid biosynthesis - lacto and neolacto series

hsa01100

Metabolic pathways

Module

hsa_M00071

Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer

hsa_M00075

N-glycan biosynthesis, complex type

Network

nt06015 N-Glycan biosynthesis
nt06035 Blood group carbohydrate antigen biosynthesis

Element

N00820

N-Glycan biosynthesis

N01666

Blood group H (O) antigen type 2 biosynthesis

Brite

KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00052 Galactose metabolism
    8704 (B4GALT2)
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    8704 (B4GALT2)
   00513 Various types of N-glycan biosynthesis
    8704 (B4GALT2)
   00515 Mannose type O-glycan biosynthesis
    8704 (B4GALT2)
   00514 Other types of O-glycan biosynthesis
    8704 (B4GALT2)
   00533 Glycosaminoglycan biosynthesis - keratan sulfate
    8704 (B4GALT2)
   00601 Glycosphingolipid biosynthesis - lacto and neolacto series
    8704 (B4GALT2)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    8704 (B4GALT2)
Enzymes [BR:hsa01000]
2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.22  lactose synthase
     8704 (B4GALT2)
    2.4.1.38  beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
     8704 (B4GALT2)
    2.4.1.90  N-acetyllactosamine synthase
     8704 (B4GALT2)
Glycosyltransferases [BR:hsa01003]
Glycan extension
  Type 2 chain/Poly-N-acetyllactosamine
   8704 (B4GALT2)

SSDB

Motif

Pfam:

Glyco_transf_7N Glyco_transf_7C Glyco_tranf_2_2

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Position

1:43979210..43991171

AA seq 372 aa
MSRLLGGTLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSRFSARGPAHALHPAASS
SSSSSNCSRPNATASSSGLPEVPSALPGPTAPTLPPCPDSPPGLVGRLLIEFTSPMPLER
VQRENPGVLMGGRYTPPDCTPAQTVAVIIPFRHREHHLRYWLHYLHPILRRQRLRYGVYV
INQHGEDTFNRAKLLNVGFLEALKEDAAYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIA
MDKFGFRLPYAGYFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRISLTGMKISRPD
IRIGRYRMIKHDRDKHNEPNPQRFTKIQNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITV
DIGRPPSWPPRG

NT seq 1119 nt +upstreamnt +downstreamnt
atgagcagactgctgggggggacgctggagcgcgtctgcaaggctgtgctccttctctgc
ctgctgcacttcctcgtggccgtcatcctctactttgacgtctacgcccagcacctggcc
ttcttcagccgcttcagtgcccgaggccctgcccatgccctccacccagctgctagcagc
agcagcagcagcagcaactgctcccggcccaacgccaccgcctctagctccgggctccct
gaggtccccagtgccctgcccggtcccacggctcccacgctgccaccctgtcctgactcg
ccacctggtcttgtgggcagactgctgatcgagttcacctcacccatgcccctggagcgg
gtgcagagggagaacccaggcgtgctcatgggcggccgatacacaccgcccgactgcacc
ccagcccagacggtggcggtcatcatcccctttagacaccgggaacaccacctgcgctac
tggctccactatctacaccccatcttgaggcggcagcggctgcgctacggcgtctatgtc
atcaaccagcatggtgaggacaccttcaaccgggccaagctgcttaacgtgggcttccta
gaggcgctgaaggaggatgccgcctatgactgcttcatcttcagcgatgtggacctggtc
cccatggatgaccgcaacctataccgctgcggcgaccaaccccgccactttgccattgcc
atggacaagtttggcttccggcttccctatgctggctactttggaggtgtgtcaggcctg
agtaaggctcagtttctgagaatcaatggcttccccaatgagtactggggctggggtggc
gaggatgatgacatcttcaaccggatctccctgactgggatgaagatctcacgcccagac
atccgaatcggccgctaccgcatgatcaagcacgaccgcgacaagcataacgaacctaac
cctcagaggtttaccaagattcaaaacacgaagctgaccatgaagcgggacggcattggg
tcagtgcggtaccaggtcttggaggtgtctcggcaaccactcttcaccaatatcacagtg
gacattgggcggcctccgtcgtggccccctcggggctga

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