KEGG T01001: 883

Homo sapiens (human): 883

Entry

883 CDS T01001

Gene name

CCBL1, GTK, KAT1, KATI

Definition

cysteine conjugate-beta lyase, cytoplasmic (EC:2.6.1.64 2.6.1.7 4.4.1.13)

Orthology

K00816

kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]

Organism

hsa Homo sapiens (human)

Pathway

hsa00380	Tryptophan metabolism
hsa00450	Selenocompound metabolism
hsa01100	Metabolic pathways
hsa05204	Chemical carcinogenesis

Class

Metabolism; Amino acid metabolism; Tryptophan metabolism [PATH:hsa00380]
Metabolism; Metabolism of other amino acids; Selenocompound metabolism [PATH:hsa00450]
Human Diseases; Cancers; Chemical carcinogenesis [PATH:hsa05204]

SSDB

Motif

Pfam:

Aminotran_1_2 Cys_Met_Meta_PP DegT_DnrJ_EryC1 Beta_elim_lyase Aminotran_5

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3FVS 3FVX 3FVU 1W7L 1W7M 1W7N

Position

9q34.11

AA seq 422 aa
MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML
NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII
IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL
NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL
TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR
QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE
PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV
EL

NT seq 1269 nt +upstreamnt +downstreamnt
atggccaaacagctgcaggcccgaaggctagacgggatcgactacaacccctgggtggag
tttgtgaaactggccagtgagcatgacgtcgtgaacttgggccagggcttcccggatttc
ccaccaccagactttgccgtggaagcctttcagcacgctgtcagtggagacttcatgctt
aaccagtacaccaagacatttggttacccaccactgacgaagatcctggcaagtttcttt
ggggagctgctgggtcaggagatagacccgctcaggaatgtgctggtgactgttggtggc
tatggggccctgttcacagccttccaggccctggtggacgaaggagacgaggtcatcatc
atcgaacccttttttgactgctacgagcccatgacaatgatggcagggggtcgtcctgtg
tttgtgtccctgaagccgggtcccatccagaatggagaactgggttccagcagcaactgg
cagctggaccccatggagctggccggcaaattcacatcacgcaccaaagccctggtcctc
aacacccccaacaaccccctgggcaaggtgttctccagggaagagctggagctggtggcc
agcctttgccagcagcatgacgtggtgtgtatcactgatgaagtctaccagtggatggtc
tacgacgggcaccagcacatcagcattgccagcctccctggcatgtgggaacggaccctg
accatcggcagcgccggcaagaccttcagcgccactggctggaaggtgggctgggtcctg
ggtccagatcacatcatgaagcacctgcggaccgtgcaccagaactccgtcttccactgc
cccacgcagagccaggctgcagtagccgagagctttgaacgggagcagctgctcttccgc
caacccagcagctactttgtgcagttcccgcaggccatgcagcgctgccgtgaccacatg
atacgtagcctacagtcagtgggcctgaagcccatcatccctcagggcagctacttcctc
atcacagacatctcagacttcaagaggaagatgcctgacttgcctggagctgtggatgag
ccctatgacagacgcttcgtcaagtggatgatcaagaacaagggcttggtggccatccct
gtctccatcttctatagtgtgccacatcagaagcactttgaccactatatccgcttctgt
tttgtgaaggatgaagccacgctccaggccatggacgagaagctgcggaagtggaaggtg
gaactctag

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (2)   
   RefSeq(pep) (3)   
DNA sequence (33)   
   RefSeq(nuc) (3)   
   GenBank (15)   
   EMBL (15)   
3D Structure (6)   
   PDB (6)   
Protein domain (5)   
   Pfam (5)   
All databases (87)   

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