KEGG   Homo sapiens (human): 8886
Entry
8886              CDS       T01001                                 
Symbol
DDX18, Has1, MrDb
Name
(RefSeq) DEAD-box helicase 18
  KO
K13179  ATP-dependent RNA helicase DDX18/HAS1 [EC:5.6.2.7]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    8886 (DDX18)
   03009 Ribosome biogenesis [BR:hsa03009]
    8886 (DDX18)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.7  DEAD-box RNA helicase
     8886 (DDX18)
Spliceosome [BR:hsa03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   RNA helicase-like proteins
    8886 (DDX18)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  90S particles
   Helicases
    8886 (DDX18)
  Pre-60S particles
    8886 (DDX18)
SSDB
Motif
Pfam: DEAD Helicase_C DUF4217 ResIII
Other DBs
NCBI-GeneID: 8886
NCBI-ProteinID: NP_006764
OMIM: 606355
HGNC: 2741
Ensembl: ENSG00000088205
UniProt: Q9NVP1 Q8N254
Structure
Position
2:117814691..117832377
AA seq 670 aa
MSHLPMKLLRKKIEKRNLKLRQRNLKFQGASNLTLSETQNGDVSEETMGSRKVKKSKQKP
MNVGLSETQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSNSESKKKKKKKRKMVND
AEPDTKKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFA
SLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVEL
IVKLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGN
GINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQT
MLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFL
KKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLL
CTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRY
LKQSKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLKQIFN
VNNLNLPQVALSFGFKVPPFVDLNVNSNEGKQKKRGGGGGFGYQKTKKVEKSKIFKHISK
KSSDSRQFSH
NT seq 2013 nt   +upstreamnt  +downstreamnt
atgtcacacctgccgatgaaactcctgcgtaagaagatcgagaagcggaacctcaaattg
cggcagcggaacctaaagtttcagggggcctcaaatctgaccctatcggaaactcaaaat
ggagatgtatctgaagaaacaatgggaagtagaaaggttaaaaaatcaaaacaaaagccc
atgaatgtgggcttatcagaaactcaaaatggaggcatgtctcaagaagcagtgggaaat
ataaaagttacaaagtctccccagaaatccactgtattaaccaatggagaagcagcaatg
cagtcttccaattcagaatcaaaaaagaaaaagaagaaaaagagaaaaatggtgaatgat
gctgagcctgatacgaaaaaagcaaaaactgaaaacaaagggaaatctgaagaagaaagt
gccgagactactaaagaaacagaaaataatgtggagaagccagataatgatgaagatgag
agtgaggtgcccagtctgcccctgggactgacaggagcttttgaggatacttcgtttgct
tctctatgtaatcttgtcaatgaaaacactctgaaggcaataaaagaaatgggttttaca
aacatgactgaaattcagcataaaagtatcagaccacttctggaaggcagggatcttcta
gcagctgcaaaaacaggcagtggtaaaaccctggcttttctcatccctgcagttgaactc
attgttaagttaaggttcatgcccaggaatggaacaggagtccttattctctcacctact
agagaactagccatgcaaacctttggtgttcttaaggagctgatgactcaccacgtgcat
acctatggcttgataatgggtggcagtaacagatctgctgaagcacagaaacttggtaat
gggatcaacatcattgtggccacaccaggccgtctgctggaccatatgcagaatacccca
ggatttatgtataaaaacctgcagtgtctggttattgatgaagctgatcgtatcttggat
gtggggtttgaagaggaattaaagcaaattattaaacttttgccaacacgtagacagact
atgctcttttctgccacccaaactcgaaaagttgaagacctggcaaggatttctctgaaa
aaggagccattgtatgttggcgttgatgatgataaagcgaatgcaacagtggatggtctt
gaacagggatatgttgtttgtccttctgaaaagagattccttctgctctttacattcctt
aagaagaaccgaaagaagaagcttatggtcttcttttcatcttgtatgtctgtgaaatac
cactatgagttgctgaactacattgatttgcccgtcttggccattcatggaaagcaaaag
caaaataagcgtacaaccacattcttccagttctgcaatgcagattcgggaacactattg
tgtacggatgtggcagcgagaggactagacattcctgaagtcgactggattgttcagtat
gaccctccggatgaccctaaggaatatattcatcgtgtgggtagaacagccagaggccta
aatgggagagggcatgccttgctcattttgcgcccagaagaattgggttttcttcgctac
ttgaaacaatccaaggttccattaagtgaatttgacttttcctggtctaaaatttctgac
attcagtctcagcttgagaaattgattgaaaagaattactttcttcataagtcagcccag
gaagcatataagtcatacatacgagcctatgattcccattctctgaaacagatctttaat
gttaataacctaaatttgcctcaggttgctctgtcatttggtttcaaggtgcctcccttc
gttgatctgaacgtcaacagtaatgaaggcaagcagaaaaagcgaggaggtggtggtgga
tttggctaccagaaaaccaagaaagttgagaaatccaaaatctttaaacacattagcaag
aaatcatctgacagcaggcagttctctcactga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
3D Structure (11)   
   PDB (11)   
Protein domain (4)   
   Pfam (4)   
All databases (80)   

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