| Entry |
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| Gene name |
CACNA1I, Cav3.3, ca(v)3.3
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| Definition |
calcium channel, voltage-dependent, T type, alpha 1I subunit
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| Orthology |
| voltage-dependent calcium channel T type alpha-1I |
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| Organism |
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| Pathway |
| MAPK signaling pathway | | Calcium signaling pathway | | Circadian entrainment |
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| Drug target |
Mibefradil: Bepridil: Prilocaine: Ethosuximide: Valproic acid: Zonisamide: Penfluridol: Flunarizine: Other: |
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| Class |
Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH: hsa04010]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH: hsa04020]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH: hsa04713]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Position |
22q13.1
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| AA seq |
2188 aa  
MAESASPPSSSAAAPAAEPGVTTEQPGPRSPPSSPPGLEEPLDGADPHVPHPDLAPIAFF
CLRQTTSPRNWCIKMVCNPWFECVSMLVILLNCVTLGMYQPCDDMDCLSDRCKILQVFDD
FIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTV
RVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCF
LEENFTIQGDVALPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKEQGRECCLSKDDV
YDFGAGRQDLNASGLCVNWNRYYNVCRTGSANPHKGAINFDNIGYAWIVIFQVITLEGWV
EIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHRLMLEQRQRYL
SSSTVASYAEPGDCYEEIFQYVCHILRKAKRRALGLYQALQSRRQALGPEAPAPAKPGPH
AKEPRHYQLCPQHSPLDATPHTLVQPIPATLASDPASCPCCQHEDGRRPSGLGSTDSGQE
GSGSGSSAGGEDEADGDGARSSEDGASSELGKEEEEEEQADGAVWLCGDVWRETRAKLRG
IVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEICNVVFTSMFALEMILKLAAFG
LFDYLRNPYNIFDSIIVIISIWEIVGQADGGLSVLRTFRLLRVLKLVRFMPALRRQLVVL
MKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVF
QILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSY
SDEDQSSSNIEEFDKLQEGLDSSGDPKLCPIPMTPNGHLDPSLPLGGHLGPAGAAGPAPR
LSLQPDPMLVALGSRKSSVMSLGRMSYDQRSLSSSRSSYYGPWGRSAAWASRRSSWNSLK
HKPPSAEHESLLSAERGGGARVCEVAADEGPPRAAPLHTPHAHHIHHGPHLAHRHRHHRR
TLSLDNRDSVDLAELVPAVGAHPRAAWRAAGPAPGHEDCNGRMPSIAKDVFTKMGDRGDR
GEDEEEIDYTLCFRVRKMIDVYKPDWCEVREDWSVYLFSPENRFRVLCQTIIAHKLFDYV
VLAFIFLNCITIALERPQIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAY
LRSSWNVLDGFLVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLV
VETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDTRNITNRSDCMAANYR
WVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNHNPWMLLYFISFL
LIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCH
TRLLIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAV
LKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARV
LKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGM
SRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCTHDERSCLSSLQFVSPLYFVSFVL
TAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAELELEMAHGLGPGPRLPTGSPGAPGRG
PGGAGGGGDTEGGLCRRCYSPAQENLWLDSVSLIIKDSLEGELTIIDNLSGSIFHHYSSP
AGCKKCHHDKQEVQLAETEAFSLNSDRSSSILLGDDLSLEDPTACPPGRKDSKGELDPPE
PMRVGDLGECFFPLSSTAVSPDPENFLCEMEEIPFNPVRSWLKHDSSQAPPSPFSPDASS
PLLPMPAEFFHPAVSASQKGPEKGTGTGTLPKIALQGSWASLRSPRVNCTLLRQATGSDT
SLDASPSSSAGSLQTTLEDSLTLSDSPRRALGPPAPAPGPRAGLSPAARRRLSLRGRGLF
SLRGLRAHQRSHSSGGSTSPGCTHHDSMDPSDEEGRGGAGGGGAGSEHSETLSSLSLTSL
FCPPPPPPAPGLTPARKFSSTSSLAAPGRPHAAALAHGLARSPSWAADRSKDPPGRAPLP
MGLGPLAPPPQPLPGELEPGDAASKRKR |
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| NT seq |
6567 nt  +upstreamnt +downstreamnt
atggctgagagcgcctccccgccctcctcatctgcagcagccccagccgctgagccagga
gtcaccacggagcagcccggaccccggagccccccatcctccccgccaggcctggaggag
cctctggatggagctgatcctcatgtcccacacccagacctggcgcctattgccttcttc
tgcctgcgacagaccaccagcccccggaactggtgcatcaagatggtgtgcaacccgtgg
tttgaatgtgtcagcatgctggtgatcctgctgaactgcgtgacacttggcatgtaccag
ccgtgcgacgacatggactgcctgtccgaccgctgcaagatcctgcaggtctttgatgac
ttcatctttatcttctttgccatggagatggtgctcaagatggtggccctggggattttt
ggcaagaagtgctacctcggggacacatggaaccgcctggatttcttcatcgtcatggca
gggatggtcgagtactccctggaccttcagaacatcaacctgtcagccatccgcaccgtg
cgcgtcctgaggcccctcaaagccatcaaccgcgtgcccagtatgcggatcctggtgaac
ctgctcctggacacactgcccatgctggggaatgtcctgctgctctgcttctttgtcttc
ttcatctttggcatcataggtgtgcagctctgggcgggcctgctgcgtaaccgctgcttc
ctggaggagaacttcaccatacaaggggatgtggccttgcccccatactaccagccggag
gaggatgatgagatgcccttcatctgctccctgtcgggcgacaatgggataatgggctgc
catgagatccccccgctcaaggagcagggccgtgagtgctgcctgtccaaggacgacgtc
tacgactttggggcggggcgccaggacctcaatgccagcggcctctgtgtcaactggaac
cgttactacaatgtgtgccgcacgggcagcgccaacccccacaagggtgccatcaacttt
gacaacatcggttatgcttggattgtcatcttccaggtgatcactctggaaggctgggtg
gagatcatgtactacgtgatggatgctcactccttctacaacttcatctacttcatcctg
cttatcatagtgggctccttcttcatgatcaacctgtgcctcgttgtcatagcgacccag
ttctcggagaccaagcaacgggagcaccggctgatgctggagcagcggcagcgctacctg
tcctccagcacggtggccagctacgccgagcctggcgactgctacgaggagatcttccag
tatgtctgccacatcctgcgcaaggccaagcgccgcgccctgggcctctaccaggccctg
cagagccggcgccaggccctgggcccggaggccccggcccccgccaaacctgggccccac
gccaaggagccccggcactaccagctgtgcccgcaacatagccccctggatgcgacgccc
cacaccctggtgcagcccatccccgccacgctggcttccgatcccgccagctgcccttgc
tgccagcatgaggacggccggcggccctcgggcctgggcagcaccgactcgggccaggag
ggctcgggctccgggagctccgctggtggcgaggacgaggcggatggggacggggcccgg
agcagcgaggacggagcctcctcagaactggggaaggaggaggaggaggaggagcaggcg
gatggggcggtctggctgtgcggggatgtgtggcgggagacgcgagccaagctgcgcggc
atcgtggacagcaagtacttcaaccggggcatcatgatggccatcctggtcaacaccgtc
agcatgggcatcgagcaccacgagcagccggaggagctgaccaacatcctggagatctgc
aatgtggtcttcaccagcatgtttgccctggagatgatcctgaagctggctgcatttggg
ctcttcgactacctgcgtaacccctacaacatcttcgacagcatcattgtcatcatcagc
atctgggagattgtggggcaggcggacggtgggctgtcggtgctgcggaccttccggctg
ctgcgcgtgctgaaactggtgcgcttcatgcctgccctgcggcgccagctcgtggtgctc
atgaagaccatggacaacgtggccaccttctgcatgctgctcatgctcttcatcttcatc
ttcagcatccttgggatgcatatttttggctgcaagttcagcctccgcacggacactgga
gacacggtgcccgacaggaagaacttcgactccctgctgtgggccatcgtcactgtgttc
cagatcctcacccaggaggactggaacgtcgttctctacaatggcatggcctccacttct
ccctgggcctccctctactttgtcgccctcatgaccttcggcaactatgtgctcttcaac
ctgctggtggccatcctggtggagggcttccaggcggagggtgacgccaatcgctcctac
tcggacgaggaccagagctcatccaacatagaagagtttgataagctccaggaaggcctg
gacagcagcggagatcccaagctctgcccaatccccatgacccccaatgggcacctggac
cccagtctcccactgggtgggcacctaggtcctgctggggctgcgggacctgccccccga
ctctcactgcagccggaccccatgctggtggccctgggctcccgaaagagcagtgtcatg
tctctagggaggatgagctatgaccagcgctccctgtccagctcccggagctcctactac
gggccatggggccgcagcgcggcctgggccagccgtcgctccagctggaacagcctcaag
cacaagccgccgtcggcggagcatgagtccctgctctctgcggagcgcggcggcggcgcc
cgggtctgcgaggttgccgcggacgaggggccgccgcgggccgcacccctgcacacccca
cacgcccaccacattcatcacgggccccatctggcgcaccgccaccgccaccaccgccgg
acgctgtccctcgacaacagggactcggtggacctggccgagctggtgcccgcggtgggc
gcccacccccgggccgcctggagggcggcaggcccggcccccgggcatgaggactgcaat
ggcaggatgcccagcatcgccaaagacgtcttcaccaagatgggcgaccgcggggatcgc
ggggaggatgaggaggaaatcgactacaccctgtgcttccgcgtccgcaagatgatcgac
gtctataagcccgactggtgcgaggtccgcgaagactggtctgtctacctcttctctccc
gagaacaggttccgggtcctgtgtcagaccattattgcccacaaactcttcgactacgtc
gtcctggccttcatctttctcaactgcatcaccatcgccctggagcggcctcagatcgag
gccggcagcaccgaacgcatctttctcaccgtgtccaactacatcttcacggccatcttc
gtgggcgagatgacattgaaggtagtctcgctgggcctgtacttcggcgagcaggcgtac
ctacgcagcagctggaacgtgctggatggctttcttgtcttcgtgtccatcatcgacatc
gtggtgtccctggcctcagccgggggagccaagatcttgggggtcctccgagtcttgcgg
ctcctgcgcaccctacgccccctgcgtgtcatcagccgggcgccgggcctgaagctggtg
gtggagacactcatctcctccctcaagcccatcggcaacatcgtgctcatctgctgtgcc
ttcttcatcatctttggcatcctgggagtgcagctcttcaagggcaagttctaccactgt
ctgggcgtggacacccgcaacatcaccaaccgctcggactgcatggccgccaactaccgc
tgggtccatcacaaatacaacttcgacaacctgggccaggctctgatgtccctctttgtc
ctggcatccaaggatggttgggtgaacatcatgtacaatggactggatgctgttgctgtg
gaccagcagcctgtgaccaaccacaacccctggatgctgctgtacttcatctccttcctg
ctcatcgtcagcttctttgtgctcaacatgtttgtgggtgtcgtggtggagaacttccac
aagtgccggcagcaccaggaggctgaagaggcacggcggcgtgaggagaagcggctgcgg
cgcctggagaagaagcgccggaaggcccagcggctgccctactatgccacctattgtcac
acccggctgctcatccactccatgtgcaccagccactacctggacatcttcatcaccttc
atcatctgcctcaacgtggtcaccatgtccctggagcactacaatcagcccacgtccctg
gagacagccctcaagtactgcaactatatgttcaccactgtctttgtgctggaggctgtg
ctgaagctggtggcatttggtctgaggcgcttcttcaaggaccgatggaaccagctggac
ctggccattgtgctactgtcagtcatgggcatcaccctggaggagatcgagatcaatgcg
gccctgcccatcaatcccaccatcatccgcatcatgagggttctgcgcattgcccgagtg
ctgaagctgttgaagatggccacaggaatgcgggccctgctggacacggtggtgcaagct
ttgccccaggtgggcaacctgggcctcctcttcatgctgctcttcttcatctatgctgct
ctcggggtggagctctttgggaagctggtctgcaacgacgagaacccgtgcgagggcatg
agccggcatgccaccttcgagaacttcggcatggccttcctcacactcttccaggtctcc
acgggtgacaactggaacgggatcatgaaggacacgctgcgggactgcacccacgacgag
cgcagctgcctgagcagcctgcagtttgtgtcgccgctgtacttcgtgagcttcgtgctc
accgcgcagttcgtgctcatcaacgtggtggtggctgtgctcatgaagcacctggacgac
agcaacaaggaggcgcaggaggacgccgagatggatgccgagctcgagctggagatggcc
catggcctgggccctggcccgaggctgcctaccggctccccgggcgcccctggccgaggg
ccgggaggggcgggcggcgggggcgacaccgagggcggcttgtgccggcgctgctactcg
cctgcccaggagaacctgtggctggacagcgtctctttaatcatcaaggactccttggag
ggggagctgaccatcatcgacaacctgtcgggctccatcttccaccactactcctcgcct
gccggctgcaagaagtgtcaccacgacaagcaagaggtgcagctggctgagacggaggcc
ttctccctgaactcagacaggtcctcgtccatcctgctgggtgacgacctgagtctcgag
gaccccacagcctgcccacctggccgcaaagacagcaagggtgagctggacccacctgag
cccatgcgtgtgggagacctgggcgaatgcttcttccccttgtcctctacggccgtctcg
ccggatccagagaacttcctgtgtgagatggaggagatcccattcaaccctgtccggtcc
tggctgaaacatgacagcagtcaagcacccccaagtcccttctccccggatgcctccagc
cctctcctgcccatgccagccgagttcttccaccctgcagtgtctgccagccagaaaggc
ccagaaaagggcactggcactggaaccctccccaagattgcgctgcagggctcctgggca
tctctgcggtcaccaagggtcaactgtaccctcctccggcaggccaccgggagcgacacg
tcgctggacgccagccccagcagctccgcgggcagcctgcagaccacgctcgaggacagc
ctgaccctgagcgacagcccccggcgtgccctggggccgcccgcgcctgctccaggaccc
cgggccggcctgtcccccgccgctcgccgccgcctgagcctgcgcggccggggcctcttc
agcctgcgggggctgcgggcgcatcagcgcagccacagcagcgggggctccaccagcccg
ggctgcacccaccacgactccatggacccctcggacgaggagggccgcggtggcgcgggc
ggcgggggcgcgggcagcgagcactcggagaccctcagcagcctctcgctcacctccctc
ttctgcccgccgcccccgccgccagcccccggcctcacgcccgccaggaagttcagcagc
accagcagcctggccgcccccggccgcccccacgccgccgccctggcccacggcctggcc
cggagcccctcgtgggccgcggaccgcagcaaggacccccccggccgggcaccgctgccc
atgggcctgggccccttggcgcccccgccgcaaccgctccccggagagctggagccggga
gacgccgccagcaagaggaagagatga |
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