KEGG   Homo sapiens (human): 8945Help
Entry
8945              CDS       T01001                                 

Gene name
BTRC, BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCP
Definition
(RefSeq) beta-transducin repeat containing E3 ubiquitin protein ligase
  KO
K03362  
F-box and WD-40 domain protein 1/11
Organism
hsa  Homo sapiens (human)
Pathway
Oocyte meiosis
Ubiquitin mediated proteolysis
Wnt signaling pathway
Hedgehog signaling pathway
Hippo signaling pathway
Circadian rhythm
Shigellosis
Module
SCF-BTRC complex
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    8945 (BTRC)
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    8945 (BTRC)
   04340 Hedgehog signaling pathway
    8945 (BTRC)
   04390 Hippo signaling pathway
    8945 (BTRC)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    8945 (BTRC)
 Organismal Systems
  Environmental adaptation
   04710 Circadian rhythm
    8945 (BTRC)
 Human Diseases
  Infectious diseases
   05131 Shigellosis
    8945 (BTRC)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   SCF complex
    Target recognizing subunit (F-box)
     8945 (BTRC)
Chromosome [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Regulators of centriole replication
     8945 (BTRC)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
10q24.32
AA seq 605 aa AA seqDB search
MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
TYISR
NT seq 1818 nt NT seq  +upstreamnt  +downstreamnt
atggacccggccgaggcggtgctgcaagagaaggcactcaagtttatgtgctctatgccc
aggtctctgtggctgggctgctccagcctggcggacagcatgccttcgctgcgatgcctg
tataacccagggactggcgcactcacagctttccagaattcctcagagagagaagactgt
aataatggcgaaccccctaggaagataataccagagaagaattcacttagacagacatac
aacagctgtgccagactctgcttaaaccaagaaacagtatgtttagcaagcactgctatg
aagactgagaattgtgtggccaaaacaaaacttgccaatggcacttccagtatgattgtg
cccaagcaacggaaactctcagcaagctatgaaaaggaaaaggaactgtgtgtcaaatac
tttgagcagtggtcagagtcagatcaagtggaatttgtggaacatcttatatcccaaatg
tgtcattaccaacatgggcacataaactcgtatcttaaacctatgttgcagagagatttc
ataactgctctgccagctcggggattggatcatattgctgagaacattctgtcatacctg
gatgccaaatcactatgtgctgctgaacttgtgtgcaaggaatggtaccgagtgacctct
gatggcatgctgtggaagaagcttatcgagagaatggtcaggacagattctctgtggaga
ggcctggcagaacgaagaggatggggacagtatttattcaaaaacaaacctcctgacggg
aatgctcctcccaactctttttatagagcactttatcctaaaattatacaagacattgag
acaatagaatctaattggagatgtggaagacatagtttacagagaattcactgccgaagt
gaaacaagcaaaggagtttactgtttacagtatgatgatcagaaaatagtaagcggcctt
cgagacaacacaatcaagatctgggataaaaacacattggaatgcaagcgaattctcaca
ggccatacaggttcagtcctctgtctccagtatgatgagagagtgatcataacaggatca
tcggattccacggtcagagtgtgggatgtaaatacaggtgaaatgctaaacacgttgatt
caccattgtgaagcagttctgcacttgcgtttcaataatggcatgatggtgacctgctcc
aaagatcgttccattgctgtatgggatatggcctccccaactgacattaccctccggagg
gtgctggtcggacaccgagctgctgtcaatgttgtagactttgatgacaagtacattgtt
tctgcatctggggatagaactataaaggtatggaacacaagtacttgtgaatttgtaagg
accttaaatggacacaaacgaggcattgcctgtttgcagtacagggacaggctggtagtg
agtggctcatctgacaacactatcagattatgggacatagaatgtggtgcatgtttacga
gtgttagaaggccatgaggaattggtgcgttgtattcgatttgataacaagaggatagtc
agtggggcctatgatggaaaaattaaagtgtgggatcttgtggctgctttggacccccgt
gctcctgcagggacactctgtctacggacccttgtggagcattccggaagagtttttcga
ctacagtttgatgaattccagattgtcagtagttcacatgatgacacaatcctcatctgg
gacttcctaaatgatccagctgcccaagctgaacccccccgttccccttctcgaacatac
acctacatctccagataa

DBGET integrated database retrieval system