KEGG T01001: 933

Homo sapiens (human): 933

Entry

933 CDS T01001

Gene name

CD22, SIGLEC-2, SIGLEC2

Definition

CD22 molecule

Orthology

K06467

CD22 antigen

Organism

hsa Homo sapiens (human)

Pathway

hsa04514	Cell adhesion molecules (CAMs)
hsa04640	Hematopoietic cell lineage
hsa04662	B cell receptor signaling pathway

Drug target

Other:

D03066 D04036 D06348 D06349 D08933 D09932

Class

Environmental Information Processing; Signaling molecules and interaction; Cell adhesion molecules (CAMs) [PATH:hsa04514]
Organismal Systems; Immune system; Hematopoietic cell lineage [PATH:hsa04640]
Organismal Systems; Immune system; B cell receptor signaling pathway [PATH:hsa04662]

SSDB

Motif

Pfam:

Ig_2 I-set Ig_3 ig C2-set_2 V-set C1-set ICAM_N Cu2_monoox_C DUF11 A2M_N_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

P20273 F5GYU4 Q0EAF5 Q32M46

Position

19q13.1

AA seq 759 aa
MHLLGPWLLLLVLEYLAFSDSSKWVFEHPETLYAWEGACVWIPCTYRALDGDLESFILFH
NPEYNKNTSKFDGTRLYESTKDGKVPSEQKRVQFLGDKNKNCTLSIHPVHLNDSGQLGLR
MESKTEKWMERIHLNVSERPFPPHIQLPPEIQESQEVTLTCLLNFSCYGYPIQLQWLLEG
VPMRQAAVTSTSLTIKSVFTRSELKFSPQWSHHGKIVTCQLQDADGKFLSNDTVQLNVKH
TPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQNTFTLNLREVT
KDQSGKYCCQVSNDVGPGRSEEVFLQVQYPPKKVTTVIQNPMPIREGDTVTLSCNYNSSN
PSVTRYEWKPHGAWEEPSLGVLKIQNVGWDNTTIACAACNSWCSWASPVALNVQYAPRDV
RVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQFFWEKNGRLLGKESQLNFDSISPEDAGS
YSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEGKSATLTCESDANPPVSHYT
WFDWNNQSLPYHSQKLRLEPVKVQHSGAYWCQGTNSVGKGRSPLSTLTVYYSPETIGRRV
AVGLGSCLAILILAICGLKLQRRWKRTQSQQGLQENSSGQSFFVRNKKVRRAPLSEGPHS
LGCYNPMMEDGISYTTLRFPEMNIPRTGDAESSEMQRPPPDCDDTVTYSALHKRQVGDYE
NVIPDFPEDEGIHYSELIQFGVGERPQAQENVDYVILKH

NT seq 2280 nt +upstreamnt +downstreamnt
atgcatctcctcggcccctggctcctgctcctggttctagaatacttggctttctctgac
tcaagtaaatgggtttttgagcaccctgaaaccctctacgcctgggagggggcctgcgtc
tggatcccctgcacctacagagccctagatggtgacctggaaagcttcatcctgttccac
aatcctgagtataacaagaacacctcgaagtttgatgggacaagactctatgaaagcaca
aaggatgggaaggttccttctgagcagaaaagggtgcaattcctgggagacaagaataag
aactgcacactgagtatccacccggtgcacctcaatgacagtggtcagctggggctgagg
atggagtccaagactgagaaatggatggaacgaatacacctcaatgtctctgaaaggcct
tttccacctcatatccagctccctccagaaattcaagagtcccaggaagtcactctgacc
tgcttgctgaatttctcctgctatgggtatccgatccaattgcagtggctcctagagggg
gttccaatgaggcaggctgctgtcacctcgacctccttgaccatcaagtctgtcttcacc
cggagcgagctcaagttctccccacagtggagtcaccatgggaagattgtgacctgccag
cttcaggatgcagatgggaagttcctctccaatgacacggtgcagctgaacgtgaagcac
accccgaagttggagatcaaggtcactcccagtgatgccatagtgagggagggggactct
gtgaccatgacctgcgaggtcagcagcagcaacccggagtacacgacggtatcctggctc
aaggatgggacctcgctgaagaagcagaatacattcacgctaaacctgcgcgaagtgacc
aaggaccagagtgggaagtactgctgtcaggtctccaatgacgtgggcccgggaaggtcg
gaagaagtgttcctgcaagtgcagtatcctcccaagaaggtgaccacagtgattcaaaac
cccatgccgattcgagaaggagacacagtgaccctttcctgtaactacaattccagtaac
cccagtgttacccggtatgaatggaaaccccatggcgcctgggaggagccatcgcttggg
gtgctgaagatccaaaacgttggctgggacaacacaaccatcgcctgcgcagcttgtaat
agttggtgctcgtgggcctcccctgtcgccctgaatgtccagtatgccccccgagacgtg
agggtccggaaaatcaagcccctttccgagattcactctggaaactcggtcagcctccaa
tgtgacttctcaagcagccaccccaaagaagtccagttcttctgggagaaaaatggcagg
cttctggggaaagaaagccagctgaattttgactccatctccccagaagatgctgggagt
tacagctgctgggtgaacaactccataggacagacagcgtccaaggcctggacacttgaa
gtgctgtatgcacccaggaggctgcgtgtgtccatgagcccgggggaccaagtgatggag
gggaagagtgcaaccctgacctgtgagagcgacgccaaccctcccgtctcccactacacc
tggtttgactggaataaccaaagcctcccctaccacagccagaagctgagattggagccg
gtgaaggtccagcactcgggtgcctactggtgccaggggaccaacagtgtgggcaagggc
cgttcgcctctcagcaccctcaccgtctactatagcccggagaccatcggcaggcgagtg
gctgtgggactcgggtcctgcctcgccatcctcatcctggcaatctgtgggctcaagctc
cagcgacgttggaagaggacacagagccagcaggggcttcaggagaattccagcggccag
agcttctttgtgaggaataaaaaggttagaagggcccccctctctgaaggcccccactcc
ctgggatgctacaatccaatgatggaagatggcattagctacaccaccctgcgctttccc
gagatgaacataccacgaactggagatgcagagtcctcagagatgcagagacctcccccg
gactgcgatgacacggtcacttattcagcattgcacaagcgccaagtgggcgactatgag
aacgtcattccagattttccagaagatgaggggattcattactcagagctgatccagttt
ggggtcggggagcggcctcaggcacaagaaaatgtggactatgtgatcctcaaacattga

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Drug (6)   
   KEGG DRUG (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (4)   
   RefSeq(pep) (4)   
DNA sequence (27)   
   RefSeq(nuc) (5)   
   GenBank (11)   
   EMBL (11)   
Protein domain (11)   
   Pfam (11)   
All databases (74)   

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