KEGG T01001: 9564

Homo sapiens (human): 9564

Entry

9564 CDS T01001

Gene name

BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas

Definition

breast cancer anti-estrogen resistance 1

Orthology

K05726

breast cancer anti-estrogen resistance 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04062	Chemokine signaling pathway
hsa04510	Focal adhesion
hsa04670	Leukocyte transendothelial migration
hsa04810	Regulation of actin cytoskeleton
hsa05100	Bacterial invasion of epithelial cells

Class

Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:hsa04810]
Cellular Processes; Cell communication; Focal adhesion [PATH:hsa04510]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:hsa04670]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:hsa04062]
Human Diseases; Infectious diseases; Bacterial invasion of epithelial cells [PATH:hsa05100]

SSDB

Motif

Pfam:

DUF3513 Serine_rich SH3_1 SH3_9 SH3_2 Vinculin

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

P56945 B2RBL9 B3KWD7 B3KWE2 B4DEV4 E9PCL5 E9PCV2 F5GXA2 F5H7Z0

Structure

PDB:

1WYX 3T6G

Position

16q23.1

AA seq 916 aa
MPAKPFLSSVLLSWKVLDFSGPGPQGTGQPCSCGHWAEGQGGPPEPAGGPNVLAKALYDN
VAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAGP
GPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPS
PQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQV
PPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPV
RGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSK
DVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDV
PPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGS
TRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPS
EPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQT
LVAHGQALDAGRGGSGATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPG
PEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVHLQGKEE
FEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTG
GLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVF
IGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVKELG
HSTQQFRRVLGQLAAA

NT seq 2751 nt +upstreamnt +downstreamnt
atgcctgccaagcccttcctctcttctgttctgctctcctggaaagttctggacttctct
ggcccagggcctcaggggactggccagccctgctcctgtgggcactgggcagagggacaa
ggcggaccacctgagcctgctggagggccgaacgtgctggccaaagcgctctatgacaat
gtggccgagtccccggatgagctctccttccgcaagggtgacatcatgacggtgctggag
caggacacgcagggcctggacggctggtggctctgctcgctgcatgggcgccagggcatc
gtgcctgggaaccgcctcaagatcttggtgggcatgtatgataagaagccagcagggcct
ggccccggccctcccgccaccccggcccagcctcagcctggcctccatgccccagcgcct
ccggcctcccagtacacgcccatgctccccaacacctaccagccccagccagacagcgtc
tacctggtgcccactcccagcaaggctcagcaaggcctctaccaagtcccgggtcccagc
cctcagttccagtctcccccagccaagcagacatccaccttctcgaagcagacaccccat
cacccgtttcccagcccggccacagacctgtaccaggtgcccccagggcctggaggccct
gcccaggatatttaccaggtgccaccttctgccgggatggggcatgacatctaccaggtc
cccccgtccatggacacacgcagctgggagggcacgaagcccccggcaaaggtggtggtg
cccacccgcgtggggcagggctatgtatacgaggccgcccagccggagcaggacgagtac
gacatcccgcgacacctgctggccccggggccacaggacatctatgatgtgcccccggtt
cgggggctgcttcccagccagtatggccaggaggtgtatgacacaccccccatggctgtc
aagggtcccaatggccgagacccgttgctggaggtgtatgacgtgccccccagtgtggag
aagggcctgccaccgtccaaccaccacgcagtctacgacgttcctccatcggtgagcaag
gatgtgcccgatggcccactgctgcgtgaggagacctacgatgtgccccccgccttcgcc
aaggccaagccctttgacccggcccgcaccccactggtactggctgcgccccctccagac
tccccgccggccgaggacgtgtatgacgtgccgcccccggctcctgacctctacgacgtg
ccccctggcttgcggcggcctggcccgggcaccctgtacgatgtgccccgtgaacgggtg
cttcctcctgaggtggctgatggtggcgtggtcgacagtggtgtgtatgcggtgcctccc
ccagctgaacgtgaagccccggcagagggcaagcgcctgtcggcctccagcaccggcagc
acacgcagcagccagtctgcgtcctccttggaggtggcagggccgggccgggaacccctg
gagctggaagttgctgtggaggccctggcacggctgcagcagggtgtgagcgccaccgtt
gcccaccttctggacctggcaggcagcgccggtgcgactgggagctggcgtagcccctct
gagccacaggagccgctggtgcaggacctgcaggctgctgtggccgctgtccagagtgcc
gtccacgagctgttggagtttgcccgcagcgcggtgggcaatgctgcccacacatctgac
cgtgccctgcatgccaagcttagccggcagctgcagaagatggaggacgtgcaccagacg
ctggtggcacatggtcaggccctcgacgctggccggggaggctctggagccacccttgag
gacctggaccggctggtggcctgctcgcgggctgtgcccgaggacgccaagcagctggcc
tccttcctgcacggcaatgcctcactgctcttcagacggaccaaggccactgccccgggg
cctgaggggggtggcaccctgcaccccaaccccactgacaagaccagcagcatccagtca
cgacccctgccctcaccccctaagttcacctcccaggactcgccagatgggcagtacgag
aacagcgaggggggctggatggaggactatgactacgtccacctacaggggaaggaggag
tttgagaagacccagaaggagctgctggaaaagggcagcatcacgcggcagggcaagagc
cagctggagttgcagcagctgaagcagtttgaacgactggaacaggaggtgtcacggccc
atagaccacgacctggccaactggacgccagcccaacccctggccccggggcgaacaggc
ggcctggggccctcggaccggcagctgctgctcttctacctggagcagtgtgaggccaac
ctgaccacactgaccaacgccgtggacgccttctttaccgccgtggccaccaaccagccg
cccaagatctttgtggcgcacagcaagttcgtcatcctcagcgcccacaagctggtgttc
atcggggacacactgtcacggcaggccaaggctgctgacgtgcgcagccaggtgacccac
tacagcaacctgctgtgcgacctcctgcgcggcatcgtggccaccaccaaggccgctgcc
ttgcagtacccatcgccttccgcggcccaggacatggtggagagggtcaaggagctgggc
cacagcacccagcagttccgccgcgtcctaggccagctggcagccgcctga

All links

Pathway (5)   
   KEGG PATHWAY (5)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (20)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (18)   
   UniProt (9)   
   RefSeq(pep) (9)   
DNA sequence (59)   
   RefSeq(nuc) (9)   
   GenBank (25)   
   EMBL (25)   
3D Structure (2)   
   PDB (2)   
Protein domain (6)   
   Pfam (6)   
All databases (120)   

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