KEGG   Homo sapiens (human): 9641Help
Entry
9641              CDS       T01001                                 

Gene name
IKBKE, IKK-E, IKK-i, IKKE, IKKI
Definition
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (EC:2.7.11.10)
Orthology
K07211  
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
Organism
hsa  Homo sapiens (human)
Pathway
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
Hepatitis C
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    9641 (IKBKE)
   04622 RIG-I-like receptor signaling pathway
    9641 (IKBKE)
   04623 Cytosolic DNA-sensing pathway
    9641 (IKBKE)
 Human Diseases
  Infectious diseases
   05162 Measles
    9641 (IKBKE)
   05164 Influenza A
    9641 (IKBKE)
   05161 Hepatitis B
    9641 (IKBKE)
   05160 Hepatitis C
    9641 (IKBKE)
   05168 Herpes simplex infection
    9641 (IKBKE)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     9641 (IKBKE)
Protein kinases [BR:hsa01001]
 Serine/threonine protein kinases: Other group
  IKK family [OT]
   9641 (IKBKE)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
1q32.1
AA seq 631 aa AA seqDB search
MEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLV
GEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYLHPDMYERAVLRKPQQKAFGVTVDLW
SIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTEKPAGAIAGAQRRENGPLEWSYTLPI
TCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFAETSDILQRVVVHVFSLSQAVLHHIY
IHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCVLEPSVSAQHIAHTTASSPLTLFSTA
IPKGLAFRDPALDVPKFVPKVDLQADYNTAKGVLGAGYQALRLARALLDGQELMFRGLHW
VMEVLQATCRRTLEVARTSLLYLSSSLGTERFSSVAGTPEIQELKAAAELRSRLRTLAEV
LSRCSQNITETQESLSSLNRELVKSRDQVHEDRSIQQIQCCLDKMNFIYKQFKKSRMRPG
LGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQKYQASLVTHGKRMRVVHETRNHLRLVG
CSVAACNTEAQGVQESLSKLLEELSHQLLQDRAKGAQASPPPIAPYPSPTRKDLLLHMQE
LCEGMKLLASDLLDNNRIIERLNRVPAPPDV
NT seq 1896 nt NT seq  +upstreamnt  +downstreamnt
atggagtactgctccagtgggagcctgctgagtgtgctggagagccctgagaatgccttt
gggctgcctgaggatgagttcctggtggtgctgcgctgtgtggtggccggcatgaaccac
ctgcgggagaacggcattgtgcatcgcgacatcaagccggggaacatcatgcgcctcgta
ggggaggaggggcagagcatctacaagctgacagacttcggcgctgcccgggagctggat
gatgatgagaagttcgtctcggtctatgggactgaggagtacctgcatcccgacatgtat
gagcgggcggtgcttcgaaagccccagcaaaaagcgttcggggtgactgtggatctctgg
agcattggagtgaccttgtaccatgcagccactggcagcctgcccttcatcccctttggt
gggccacggcggaacaaggagatcatgtaccggatcaccacggagaagccggctggggcc
attgcaggtgcccagaggcgggagaacgggcccctggagtggagctacaccctccccatc
acctgccagctgtcactggggctgcagagccagctggtgcccatcctggccaacatcctg
gaggtggagcaggccaagtgctggggcttcgaccagttctttgcggagaccagtgacatc
ctgcagcgagttgtcgtccatgtcttctccctgtcccaggcagtcctgcaccacatctat
atccatgcccacaacacgatagccattttccaggaggccgtgcacaagcagaccagtgtg
gccccccgacaccaggagtacctctttgagggtcacctctgtgtcctcgagcccagcgtc
tcagcacagcacatcgcccacacgacggcaagcagccccctgaccctcttcagcacagcc
atccctaaggggctggccttcagggaccctgctctggacgtccccaagttcgtccccaaa
gtggacctgcaggcggattacaacactgccaagggcgtgttgggcgccggctaccaggcc
ctgcggctggcacgggccctgctggatgggcaggagctaatgtttcgggggctgcactgg
gtcatggaggtgctccaggccacatgcagacggactctggaagtggcaaggacatccctc
ctctacctcagcagcagcctgggaactgagaggttcagcagcgtggctggaacgcctgag
atccaggaactgaaggcggctgcagaactgaggtccaggctgcggactctagcggaggtc
ctctccagatgctcccaaaatatcacggagacccaggagagcctgagcagcctgaaccgg
gagctggtgaagagccgggatcaggtacatgaggacagaagcatccagcagattcagtgc
tgtttggacaagatgaacttcatctacaaacagttcaagaagtctaggatgaggccaggg
cttggctacaacgaggagcagattcacaagctggataaggtgaatttcagtcatttagcc
aaaagactcctgcaggtgttccaggaggagtgcgtgcagaagtatcaagcgtccttagtc
acacacggcaagaggatgagggtggtgcacgagaccaggaaccacctgcgcctggttggc
tgttctgtggctgcctgtaacacagaagcccagggggtccaggagagtctcagcaagctc
ctggaagagctatctcaccagctccttcaggaccgagcaaagggggctcaggcctcgccg
cctcccatagctccttaccccagccctacacgaaaggacctgcttctccacatgcaagag
ctctgcgaggggatgaagctgctggcatctgacctcctggacaacaaccgcatcatcgaa
cggctaaatagagtcccagcacctcctgatgtctga

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