KEGG   Homo sapiens (human): 972Help
Entry
972               CDS       T01001                                 

Gene name
CD74, DHLAG, HLADG, II, Ia-GAMMA
Definition
(RefSeq) CD74 molecule
  KO
K06505  CD74 antigen
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa05152  Tuberculosis
hsa05168  Herpes simplex infection
Drug target
Milatuzumab: D08944
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Organismal Systems
  Immune system
   04612 Antigen processing and presentation
    972 (CD74)
 Human Diseases
  Infectious diseases
   05152 Tuberculosis
    972 (CD74)
   05168 Herpes simplex infection
    972 (CD74)
CD molecules [BR:hsa04090]
 Proteins
  972 (CD74)
Proteoglycans [BR:hsa00535]
 Cell surface proteoglycans
  Others
   972 (CD74)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MHC2-interact MHCassoc_trimer Thyroglobulin_1
Motif
Other DBs
NCBI-GeneID: 972
NCBI-ProteinID: NP_001020330
OMIM: 142790
HGNC: 1697
Ensembl: ENSG00000019582
Vega: OTTHUMG00000163559
Pharos: P04233(Tchem)
UniProt: P04233
Structure
PDB: 

Jmol
Position
5q33.1
AA seq 296 aa AA seqDB search
MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL
LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM
GALPQGPMQNATKYGNMTEDHVMHLLQNADPLKVYPPLKGSFPENLRHLKNTMETIDWKV
FESWMHHWLLFEMSRHSLEQKPTDAPPKVLTKCQEEVSHIPAVHPGSFRPKCDENGNYLP
LQCYGSIGYCWCVFPNGTEVPNTRSRGHHNCSESLELEDPSSGLGVTKQDLGPVPM
NT seq 891 nt NT seq  +upstreamnt  +downstreamnt
atgcacaggaggagaagcaggagctgtcgggaagatcagaagccagtcatggatgaccag
cgcgaccttatctccaacaatgagcaactgcccatgctgggccggcgccctggggccccg
gagagcaagtgcagccgcggagccctgtacacaggcttttccatcctggtgactctgctc
ctcgctggccaggccaccaccgcctacttcctgtaccagcagcagggccggctggacaaa
ctgacagtcacctcccagaacctgcagctggagaacctgcgcatgaagcttcccaagcct
cccaagcctgtgagcaagatgcgcatggccaccccgctgctgatgcaggcgctgcccatg
ggagccctgccccaggggcccatgcagaatgccaccaagtatggcaacatgacagaggac
catgtgatgcacctgctccagaatgctgaccccctgaaggtgtacccgccactgaagggg
agcttcccggagaacctgagacaccttaagaacaccatggagaccatagactggaaggtc
tttgagagctggatgcaccattggctcctgtttgaaatgagcaggcactccttggagcaa
aagcccactgacgctccaccgaaagtactgaccaagtgccaggaagaggtcagccacatc
cctgctgtccacccgggttcattcaggcccaagtgcgacgagaacggcaactatctgcca
ctccagtgctatgggagcatcggctactgctggtgtgtcttccccaacggcacggaggtc
cccaacaccagaagccgcgggcaccataactgcagtgagtcactggaactggaggacccg
tcttctgggctgggtgtgaccaagcaggatctgggcccagtccccatgtga

DBGET integrated database retrieval system