KEGG   Homo sapiens (human): 10715
Entry
10715             CDS       T01001                                 
Symbol
CERS1, EPM8, GDF-1, GDF1, LAG1, LASS1, UOG1
Name
(RefSeq) ceramide synthase 1
  KO
K04710  sphingoid base N-stearoyltransferase [EC:2.3.1.299]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00600  Sphingolipid metabolism
hsa01100  Metabolic pathways
hsa04071  Sphingolipid signaling pathway
Module
hsa_M00094  Ceramide biosynthesis
hsa_M00099  Sphingosine biosynthesis
Disease
H00810  Progressive myoclonic epilepsy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    10715 (CERS1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    10715 (CERS1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.299  sphingoid base N-stearoyltransferase
     10715 (CERS1)
SSDB
Motif
Pfam: TRAM_LAG1_CLN8
Other DBs
NCBI-GeneID: 10715
NCBI-ProteinID: NP_067090
OMIM: 606919
HGNC: 14253
Ensembl: ENSG00000223802
UniProt: P27544
Position
19:complement(18868545..18896982)
AA seq 350 aa
MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPEL
LLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYLL
FGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVML
LHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAA
DLGCLSFGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFL
YIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAEKPLRNGLVKDKRF
NT seq 1053 nt   +upstreamnt  +downstreamnt
atggcggcggcggggcccgcggcggggccgacggggcccgagcccatgccgagctacgcg
cagctagtgcagcgcggctggggcagcgcgctggcggcggcgcggggctgcacggactgc
ggctgggggctggcgcgtcgcggcctggctgagcacgcgcacctggcgccgcccgagctg
ctgctgctggcgctcggcgcgctgggctggaccgccctgcgctccgcggccactgcgcgc
ctctttcggcccctggcgaagcggtgctgcctccagcccagagatgccgccaagatgccc
gagagcgcttggaagtttctcttctacctgggcagctggagctacagtgcctacctgctg
tttggcaccgactaccccttcttccatgacccaccatctgtcttctacgactggacgccg
ggcatggcagtgccacgggacattgcagccgcctacctgctccagggaagcttctatggc
cactccatctacgctacgctatacatggacacctggcgcaaggactcggtggtcatgctg
ctccaccacgtggtcactctcatcctcatcgtctcctcctacgccttccggtaccacaat
gtgggcatccttgtgctcttcctgcacgatatcagtgacgtgcagcttgagttcaccaag
ctcaacatttacttcaagtcccgcggcggctcctaccatcggctgcatgccttggcagca
gacttgggctgcctcagcttcggcttcagctggttctggttccgcctctactggttcccg
ctcaaggtcctgtatgccaccagtcactgcagtctgcgcacggtgcctgacatccccttc
tacttcttcttcaatgcgctcctgctgctgctcacccttatgaacctctactggttcctg
tacatcgtggcgtttgcagccaaggtgttgacaggccaggtgcacgagctgaaggacctg
cgggagtatgacacagccgaggcccagagcctgaagcccagcaaagccgagaagccactg
aggaacggcctggtgaaggacaagcgcttctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (28)   
   RefSeq(nuc) (10)   
   GenBank (9)   
   EMBL (9)   
Protein domain (1)   
   Pfam (1)   
All databases (84)   

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