KEGG   Homo sapiens (human): 2762
Entry
2762              CDS       T01001                                 
Symbol
GMDS, GMD, SDR3E1
Name
(RefSeq) GDP-mannose 4,6-dehydratase
  KO
K01711  GDPmannose 4,6-dehydratase [EC:4.2.1.47]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00051  Fructose and mannose metabolism
hsa00520  Amino sugar and nucleotide sugar metabolism
hsa01100  Metabolic pathways
hsa01250  Biosynthesis of nucleotide sugars
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    2762 (GMDS)
   00520 Amino sugar and nucleotide sugar metabolism
    2762 (GMDS)
Enzymes [BR:hsa01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.47  GDP-mannose 4,6-dehydratase
     2762 (GMDS)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase RmlD_sub_bind Polysacc_synt_2 NmrA
Other DBs
NCBI-GeneID: 2762
NCBI-ProteinID: NP_001491
OMIM: 602884
HGNC: 4369
Ensembl: ENSG00000112699
UniProt: O60547
Structure
Position
6:complement(1623806..2245605)
AA seq 372 aa
MAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSF
NTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDL
AEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYG
AAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSL
GNLDAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWEG
KNENEVGRCKETGKVHVTVDLKYYRPTEVDFLQGDCTKAKQKLNWKPRVAFDELVREMVH
ADVELMRTNPNA
NT seq 1119 nt   +upstreamnt  +downstreamnt
atggcacacgcaccggcacgctgccccagcgcccggggctccggggacggcgagatgggc
aagcccaggaacgtggcgctcatcaccggtatcacaggccaggatggttcctacctggct
gagttcctgctggagaaaggctatgaggtccatggaattgtacggcggtccagttcattt
aatacgggtcgaattgagcatctgtataagaatccccaggctcacattgaaggaaacatg
aagttgcactatggcgatctcactgacagtacctgccttgtgaagatcattaatgaagta
aagcccacagagatctacaaccttggagcccagagccacgtcaaaatttcctttgacctc
gctgagtacactgcggacgttgacggagttggcactctacgacttctagatgcagttaag
acttgtggccttatcaactctgtgaagttctaccaagcctcaacaagtgaactttatggg
aaagtgcaggaaataccccagaaggagaccacccctttctatccccggtcaccctatggg
gcagcaaaactctatgcctattggattgtggtgaacttccgtgaggcgtataatctcttt
gcagtgaacggcattctcttcaatcatgagagtcccagaagaggagctaatttcgttact
cgaaaaattagccggtcagtagctaagatttaccttggacaactggaatgtttcagtttg
ggaaatctggatgccaaacgagattggggccatgccaaggactatgtggaggctatgtgg
ttgatgttgcagaatgatgagccggaggacttcgttatagctactggggaggtccatagt
gtccgggaatttgtcgagaaatcattcttgcacattggaaaaaccattgtgtgggaagga
aagaatgaaaatgaagtgggcagatgtaaagagaccggcaaagttcacgtgactgtggat
ctcaagtactaccggccaactgaagtggactttctgcagggcgactgcaccaaagcgaaa
cagaagctgaactggaagccccgggtcgctttcgatgagctggtgagggagatggtgcac
gccgacgtggagctcatgaggacaaaccccaatgcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (21)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (19)   
DNA sequence (45)   
   RefSeq(nuc) (21)   
   GenBank (12)   
   EMBL (12)   
3D Structure (7)   
   PDB (7)   
Protein domain (5)   
   Pfam (5)   
All databases (104)   

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