KEGG   Homo sapiens (human): 4121
Entry
4121              CDS       T01001                                 
Symbol
MAN1A1, HUMM3, HUMM9, MAN9
Name
(RefSeq) mannosidase alpha class 1A member 1
  KO
K01230  mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00510  N-Glycan biosynthesis
hsa00513  Various types of N-glycan biosynthesis
hsa01100  Metabolic pathways
hsa04141  Protein processing in endoplasmic reticulum
Module
hsa_M00073  N-glycan precursor trimming
Network
nt06015  N-Glycan biosynthesis
  Element
N00820  N-Glycan biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    4121 (MAN1A1)
   00513 Various types of N-glycan biosynthesis
    4121 (MAN1A1)
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    4121 (MAN1A1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    4121 (MAN1A1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.113  mannosyl-oligosaccharide 1,2-alpha-mannosidase
     4121 (MAN1A1)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    4121 (MAN1A1)
SSDB
Motif
Pfam: Glyco_hydro_47 AIM5 DnaB_bind
Other DBs
NCBI-GeneID: 4121
NCBI-ProteinID: NP_005898
OMIM: 604344
HGNC: 6821
Ensembl: ENSG00000111885
UniProt: P33908
Position
6:complement(119177205..119350605)
AA seq 653 aa
MPVGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIF
FLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPEAALEDN
LARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPI
GVESREPADAAIREKRAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGAT
IVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEI
FRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHL
SHLSGNPIFAEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLL
KAWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGG
MFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEK
YYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDD
VQQSFFLAETLKYLYLIFSDDDLLPLEHWIFNSEAHLLPILPKDKKEVEIREE
NT seq 1962 nt   +upstreamnt  +downstreamnt
atgcccgtggggggcctgttgccgctcttcagcagccccgcgggcggcgtcctgggcggg
gggctcggcggcggcggtggcaggaaggggtcgggccccgccgccctccgcctgacggag
aagttcgtgctgctgctggtattcagcgccttcatcacgctctgcttcggggcgatcttc
ttcctgccagactcctccaagctgctcagcggggtcctgttccactccagccccgccttg
cagccggccgccgaccacaagcccgggcccggggcgcgcgccgaggacgcggccgagggg
cgagcccggcgccgcgaggagggggcacccggggacccggaggccgccctggaggacaac
ttggccaggatccgcgaaaaccacgagcgggctctcagggaagccaaggagaccctgcag
aagctgcccgaggagatccaaagagacatcctactggagaagaagaaggtggcccaggac
cagctgcgtgacaaggcgccgttcagaggcctgcccccggtggacttcgtgcccccaatc
ggggtggagagccgggagcccgccgacgccgccatccgcgagaaaagggcaaagatcaaa
gagatgatgaaacatgcttggaataattataaaggttatgcctggggattaaatgaactc
aaacctatatcaaaaggaggccattcaagcagtttgtttggtaacatcaaaggagcaact
atagtagatgccctggatacactttttattatggaaatgaaacatgaatttgaagaagca
aaatcatgggttgaagaaaatttagattttaatgtgaatgctgaaatttctgtctttgaa
gtaaatatacgctttgttggtggactactctcagcctactatctgtctggagaagagatt
tttcgaaagaaagcagtggaacttggggtaaaattgctacctgcatttcatactccctct
ggaataccttgggcattgctgaatatgaaaagtggtattggaaggaactggccctgggcc
tctggaggcagcagtattctggcagaatttggaaccctgcatttggagtttatgcacttg
agccacttatcaggaaaccccatctttgctgaaaaggtaatgaatattcgaacagtactg
aacaaactggaaaaaccacaaggcctttatcctaactatctgaatcccagtagtggacag
tggggtcaacatcatgtatcagttggaggacttggagacagcttctatgagtatttgctg
aaggcctggttaatgtctgacaagacagatctggaagctaagaagatgtattttgatgct
gttcaggctatcgagactcatttgatccgcaagtctagcagcggactaacttatatcgca
gagtggaaagggggcctcctggagcacaagatgggccacctgacctgcttcgcggggggc
atgttcgcactcggggctgatgcagctcccgaaggcatggcccaacactaccttgaactc
ggggctgaaattgcccgtacttgtcatgaatcatataatcgaacatttatgaaactggga
ccagaagctttcagatttgatggtggtgttgaagccatcgctacaagacaaaatgaaaaa
tactacatcttacggccagaagttatggagacttacatgtatatgtggagactgactcat
gatccaaagtacaggaaatgggcctgggaagccgtagaggccttggaaaaccattgcaga
gtgaatggaggctattcaggcctaagggatgtttaccttcttcatgagagttatgatgat
gtgcagcagagtttcttcctggcagagacattgaaatatttgtacctaatattttctgac
gacgatcttcttccactggagcattggatcttcaatagcgaggcacatcttctccctatc
ctccctaaagataaaaaggaagttgaaatcagagaggaataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (19)   
   RefSeq(nuc) (7)   
   GenBank (6)   
   EMBL (6)   
Protein domain (3)   
   Pfam (3)   
All databases (66)   

Download RDF
DBGET integrated database retrieval system