KEGG   Homo sapiens (human): 4143
Entry
4143              CDS       T01001                                 
Symbol
MAT1A, MAT, MATA1, SAMS, SAMS1
Name
(RefSeq) methionine adenosyltransferase 1A
  KO
K00789  S-adenosylmethionine synthetase [EC:2.5.1.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00270  Cysteine and methionine metabolism
hsa01100  Metabolic pathways
hsa01230  Biosynthesis of amino acids
hsa01240  Biosynthesis of cofactors
Module
hsa_M00034  Methionine salvage pathway
hsa_M00035  Methionine degradation
Network
nt06030  Methionine metabolism
  Element
N01607  Methionine degradation
Disease
H00184  Hypermethioninemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    4143 (MAT1A)
Enzymes [BR:hsa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.6  methionine adenosyltransferase
     4143 (MAT1A)
SSDB
Motif
Pfam: S-AdoMet_synt_C S-AdoMet_synt_M S-AdoMet_synt_N AdoMet_Synthase
Other DBs
NCBI-GeneID: 4143
NCBI-ProteinID: NP_000420
OMIM: 610550
HGNC: 6903
Ensembl: ENSG00000151224
UniProt: Q00266
Structure
Position
10:complement(80271820..80289658)
AA seq 395 aa
MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC
KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC
VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
NT seq 1188 nt   +upstreamnt  +downstreamnt
atgaatggaccggtggatggcttgtgtgaccactctctaagtgaaggagtcttcatgttc
acatcggagtctgtgggagagggacacccggataagatctgtgaccagatcagtgatgca
gtgctggatgcccatctcaagcaagaccccaatgccaaggtggcctgtgagacagtgtgc
aagaccggcatggtgctgctgtgtggtgagatcacctcaatggccatggtggactaccag
cgggtggtgagggacaccatcaagcacatcggctacgatgactcagccaagggctttgac
ttcaagacttgcaacgtgctggtggctttggagcagcaatccccagatattgcccagtgc
gtccatctggacagaaatgaggaggatgtgggggcaggagatcagggtttgatgttcggc
tatgctaccgacgagacagaggagtgcatgcccctcaccatcatccttgctcacaagctc
aacgcccggatggcagacctcaggcgctccggcctcctcccctggctgcggcctgactct
aagactcaggtgacagttcagtacatgcaggacaatggcgcagtcatccctgtgcgcatc
cacaccatcgtcatctctgtgcagcacaacgaagacatcacgctggaggagatgcgcagg
gccctgaaggagcaagtcatcagggccgtggtgccggccaagtacctggacgaagacacc
gtctaccacctgcagcccagtgggcggtttgtcatcggaggtccccagggggatgcgggt
gtcactggccgtaagattattgtggacacctatggcggctggggggctcatggtggtggg
gccttctctgggaaggactacaccaaggtagaccgctcagctgcatatgctgcccgctgg
gtggccaagtctctggtgaaagcagggctctgccggagagtgcttgtccaggtttcctat
gccattggtgtggccgagccgctgtccatttccatcttcacctacggaacctctcagaag
acagagcgagagctgctggatgtggtgcataagaacttcgacctccggccgggcgtcatt
gtcagggatttggacttgaagaagcccatctaccagaagacagcatgctacggccatttc
ggaagaagcgagttcccatgggaggttcccaggaagcttgtattttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (4)   
   KEGG MODULE (5)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
3D Structure (4)   
   PDB (4)   
Protein domain (4)   
   Pfam (4)   
All databases (72)   

Download RDF
DBGET integrated database retrieval system