KEGG   Homo sapiens (human): 64895
Entry
64895             CDS       T01001                                 
Symbol
PAPOLG
Name
(RefSeq) poly(A) polymerase gamma
  KO
K14376  poly(A) polymerase [EC:2.7.7.19]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    64895 (PAPOLG)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    64895 (PAPOLG)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.19  polynucleotide adenylyltransferase
     64895 (PAPOLG)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Poly(A) addition factors
     64895 (PAPOLG)
SSDB
Motif
Pfam: PAP_NTPase PAP_central PAP_RNA-bind NTP_transf_2 Nrap_D2 DUF4269
Other DBs
NCBI-GeneID: 64895
NCBI-ProteinID: NP_075045
OMIM: 616865
HGNC: 14982
Ensembl: ENSG00000115421
UniProt: Q9BWT3
Structure
Position
2:60756268..60802086
AA seq 736 aa
MKEMSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHR
LVVLGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAP
RHVERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDN
LDLRDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNML
GFLGGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWD
PRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKL
LEPPNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSF
PGNKEHHKDNNYVSMWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEGM
KIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNRSSGGLQSKRLSLDSSCLDSSRDTDNG
TPFNSPASKSDSPSVGETERNSAEPAAVIVEKPLSVPPAQGLSIPVIGAKVDSTVKTVSP
PTVCTIPTVVGRNVIPRITTPHNPAQGQPHLNGMSNITKTVTPKRSHSPSIDGTPKRLKD
VEKFIRLESTFKDPRTAEERKRKSVDAIGGESMPIPTIDTSRKKRLPSKELPDSSSPVPA
NNIRVIKNSIRLTLNR
NT seq 2211 nt   +upstreamnt  +downstreamnt
atgaaagagatgtctgcaaacaccgtgctggacagccagcgtcaacaaaagcattatgga
attacctccccaattagtttggcatctcctaaagaaattgatcatatttacacacagaaa
ttaattgacgccatgaaaccatttggagtgtttgaagatgaggaagaattgaaccacagg
ctggtggttcttggtaaattgaacaatttagtaaaagaatggatttctgatgtcagcgag
agtaagaacctcccaccttctgttgtggctactgttggtggtaaaattttcacatttgga
tcctataggcttggagtacacaccaaaggagctgacattgatgcactttgtgtagctcca
agacatgtggaaagatctgatttttttcagtctttttttgaaaaattgaaacatcaagat
ggcattagaaacttaagagctgtagaagatgcctttgtacctgttataaaatttgaattt
gatggtattgaaattgatctagtctttgcaagactggcaatacaaaccatatcagataat
ttagatctaagagacgactctcgcctgagaagccttgatataaggtgtattcgcagctta
aatggttgtagagttactgatgaaattttgcatttagtgccaaataaagaaacttttaga
ctcaccctaagagctgtcaaattatgggcaaaacgacgtggtatttattccaacatgcta
ggattccttggtggtgtctcctgggcaatgctagttgcaagaacttgccaattgtatcca
aatgcagcagcatctactttagttcataagttctttttagttttttccaagtgggaatgg
ccaaatcctgtgctgctgaagcaaccagaagaaagcaatttgaatttgcctgtctgggat
cctcgggtaaatccatcagataggtatcatctcatgcccataatcacccctgcctaccca
caacagaattctacgtataatgtgtccacatcaactcgaacagtaatggtagaagaattt
aaacaaggtcttgcagtcacagatgaaattcttcaaggaaagtcagattggtccaaacta
cttgagccaccgaatttctttcaaaagtatagacattatatagtattgactgccagcgca
tcaacagaagaaaaccatctagagtgggttggattagtagaatctaaaatccgtgtactt
gttggaaacttggaacggaatgaatttattactcttgcccatgtgaatccccagtcattc
ccagggaataaggaacatcataaagacaacaattacgtatcaatgtggttccttgggata
atttttcggagagtagaaaatgcagaaagtgtcaacatagacttgacatatgatatacag
tcatttactgatacagtgtacagacaggcaaacaatataaatatgctaaaggagggaatg
aaaattgaagcaactcatgtaaagaaaaaacaacttcaccactaccttcctgcagaaatt
cttcaaaagaagaaaaagcaaagtctctctgatgtcaatcgaagctcgggcggacttcaa
tccaaaagattgtctctggatagcagttgtctggatagctccagagacactgataatgga
acaccttttaattctccagcgtccaagtctgatagcccttctgtaggagaaacagaaagg
aatagtgctgagcctgctgctgtaattgtggagaagccactgagtgtaccaccagcccaa
ggactttccattccagtgattggcgcaaaagttgactctacagtaaaaactgtatcaccc
cccactgtgtgtaccattcctaccgtagtaggacgaaatgtcattcctagaatcacaaca
cctcacaaccctgcccagggacaaccgcatctgaatggaatgtcaaatataactaagact
gttacacctaagagatcccattccccatccatagatgggactcctaagaggttgaaagac
gtagaaaagtttattcgacttgaatcaacatttaaggacccccgcactgctgaagaaaga
aaaagaaaatcagtggatgccattggaggagaatctatgcctattccaactattgataca
tcacgcaaaaagagactacccagtaaagaactaccagattcatcatctccagttccagca
aacaacatccgtgtcatcaaaaattccattcgactgacccttaatcggtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (45)   
   RefSeq(nuc) (7)   
   GenBank (19)   
   EMBL (19)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (6)   
All databases (81)   

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