KEGG   Homo sapiens (human): 26007
Entry
26007             CDS       T01001                                 
Symbol
TKFC, DAK, NET45, TKFCD
Name
(RefSeq) triokinase and FMN cyclase
  KO
K00863  triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00051  Fructose and mannose metabolism
hsa00561  Glycerolipid metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa04622  RIG-I-like receptor signaling pathway
Disease
H02727  Triokinase and FMN cyclase deficiency syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    26007 (TKFC)
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    26007 (TKFC)
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    26007 (TKFC)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.28  triokinase
     26007 (TKFC)
    2.7.1.29  glycerone kinase
     26007 (TKFC)
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.15  FAD-AMP lyase (cyclizing)
     26007 (TKFC)
SSDB
Motif
Pfam: Dak1 Dak2
Other DBs
NCBI-GeneID: 26007
NCBI-ProteinID: NP_056348
OMIM: 615844
HGNC: 24552
Ensembl: ENSG00000149476
UniProt: Q3LXA3 A0A140VJH7
Position
11:61333228..61353426
AA seq 575 aa
MTSKKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDSLKGRVALLSGGGSGHE
PAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVAQAGTVGTLLIVKNYTGDRLNFGL
AREQARAEGIPVEMVVIGDDSAFTVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEEIAKQ
VNVVAKAMGTLGVSLSSCSVPGSKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKL
MLDHMTNTTNASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALV
GTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEA
PDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLK
EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLPAWSAAMDAGLE
AMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAG
AGRASYISSARLEQPDPGAVAAAAILRAILEVLQS
NT seq 1728 nt   +upstreamnt  +downstreamnt
atgacctccaagaagctggtgaactcggtggctggctgtgctgatgacgctcttgctggc
ctggtggcctgcaaccccaacctgcagctcctgcagggccaccgcgtggccctccgttct
gacctggacagcctcaagggccgggtggcactgctgtcgggtgggggctctggccatgag
cctgcccatgctggtttcatagggaaggggatgctgactggggtcatcgcgggagctgtg
ttcacctccccggcagtgggcagcatcctggcagccatcagggccgtggcccaggccggc
acagtggggacgctccttatcgtgaagaactacactggggatcggctcaacttcggcctg
gcccgggagcaggcccgggctgaaggcatcccggtggagatggtggtgattggggacgac
agcgccttcactgtcctgaagaaggcaggccggcgggggctgtgcggcacggtgcttata
cacaaggtggcaggtgctctggctgaggctggtgtggggctggaggagatcgcaaagcag
gtgaacgtggtcgccaaggccatgggtaccctgggggtgagcttatcctcctgcagcgtc
cctggttccaaacccaccttcgagctctcagccgacgaggtggagctgggcctggggatc
cacggggaagctggtgtgcgccggataaagatggcaaccgccgatgagattgtgaaactc
atgctcgaccacatgacaaacaccaccaacgcgtcccatgtgcctgtgcagcccggctcc
tcagttgtgatgatggtcaacaacctgggtggcctgtcattcctggaactgggcatcata
gccgacgctaccgtccgctccctggagggccgcggggtgaagattgcccgtgccctggtg
ggcaccttcatgtcagcactggagatgcctggcatttctctcaccctcctgctggtggat
gagcctctcctgaaactgatagatgctgaaaccactgcagcagcctggcctaacgtggct
gcagtctccattactgggcggaagcggagccgggtagcccctgccgagccccaggaggcc
cctgattccactgctgcaggaggctcagcctcgaagcggatggcgctggtgctggaacgg
gtgtgcagcactctcctgggcctggaggaacacctgaatgccctggaccgggctgctggt
gacggcgactgtggcaccacccacagccgtgcggccagagcaatccaggagtggctgaag
gagggcccaccccctgccagccctgcccagctgctctccaagttgtctgtcctgctcctg
gagaagatgggaggctcatctggggcgctctatggcctgttcctgactgcggctgcacag
cccctgaaggccaagaccagcctcccagcctggtctgctgccatggatgccggcctggaa
gccatgcagaagtatggcaaggctgctccaggggacaggactatgctggattctctgtgg
gcagcggggcaggagctccaagcctggaagagcccaggagctgatctgttacaagtcctg
accaaagcagtcaagagtgccgaagctgcagccgaggccaccaagaatatggaagctgga
gccggaagagccagttatatcagctcagcacggctggagcagccagaccccggggcggtg
gcagctgctgccatcctccgggccatcttggaggtcttgcagagctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (5)   
   KEGG ENZYME (3)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (39)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (36)   
DNA sequence (62)   
   RefSeq(nuc) (36)   
   GenBank (13)   
   EMBL (13)   
Protein domain (2)   
   Pfam (2)   
All databases (136)   

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