ORTHOLOGY: K05084 Help
Entry
Symbol
ERBB3, HER3
Name
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1 ]
Pathway
map01521 EGFR tyrosine kinase inhibitor resistance
Disease
H00408 Type 1 diabetes mellitus
H00865 Lethal congenital contractural syndrome
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
04012 ErbB signaling pathway
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
04020 Calcium signaling pathway
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
04151 PI3K-Akt signaling pathway
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
05205 Proteoglycans in cancer
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
Enzymes [BR:ko01000 ]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
Protein kinases [BR:ko01001 ]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
BRITE hierarchy
Genes
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Taxonomy UniProt
Reference
Authors
Kraus MH, Issing W, Miki T, Popescu NC, Aaronson SA
Title
Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors.
Journal
Sequence