KEGG ORTHOLOGY: K05732

ORTHOLOGY: K05732

Entry

K05732                      KO

Symbol

ARHGAP35, GRLF1

Name

glucocorticoid receptor DNA-binding factor 1

Pathway

map04510

Focal adhesion

map04611

Platelet activation

map04670

Leukocyte transendothelial migration

map04810

Regulation of actin cytoskeleton

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05732  ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05732  ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K05732  ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
   04670 Leukocyte transendothelial migration
    K05732  ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05732  ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
Membrane trafficking [BR:ko04131]
Others
  Rho GTPase associated proteins
   Rho GTPase-activating proteins
    K05732  ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1

Other DBs

GO:

0005096

Genes

HSA:	2909(ARHGAP35)

PTR:	456157(ARHGAP35)

PPS:	100975102(ARHGAP35)

GGO:	101153846(ARHGAP35)

PON:	100450933(ARHGAP35)

NLE:	100587473(ARHGAP35)

HMH:	116478299(ARHGAP35)

MCC:	716936(ARHGAP35)

MCF:	102114959(ARHGAP35)

MTHB:

126943404

MNI:	105478593(ARHGAP35)

CSAB:

103234927(ARHGAP35)

CATY:

105595194(ARHGAP35)

PANU:

101020203(ARHGAP35)

TGE:	112612165(ARHGAP35)

MLEU:

105531723(ARHGAP35)

RRO:	104673397(ARHGAP35)

RBB:

108531061

TFN:	117091457(ARHGAP35)

PTEH:

111519926(ARHGAP35)

CANG:

105526847(ARHGAP35)

CJC:	100385925(ARHGAP35)

SBQ:	101032805(ARHGAP35)

CIMI:

108283832(ARHGAP35)

CSYR:

103266429(ARHGAP35)

MMUR:

105869577(ARHGAP35)

LCAT:

123623910(ARHGAP35)

PCOQ:

105817661(ARHGAP35)

OGA:	100943600(ARHGAP35)

MMU:	232906(Arhgap35)

MCAL:

110297432(Arhgap35)

MPAH:

110336309(Arhgap35)

RNO:	306400(Arhgap35)

MCOC:

116101687(Arhgap35)

ANU:	117700415(Arhgap35)

MUN:	110561313(Arhgap35)

CGE:	100752481(Arhgap35)

MAUA:

101825449(Arhgap35)

PROB:

127238347(Arhgap35)

PLEU:

114681429(Arhgap35)

MORG:

121450220(Arhgap35)

MFOT:

126493318

AAMP:

119820528(Arhgap35)

NGI:	103724803(Arhgap35)

HGL:	101719355(Arhgap35)

CPOC:

100718086(Arhgap35)

CCAN:

109691158(Arhgap35)

DORD:

105998119(Arhgap35)

DSP:	122125742(Arhgap35)

PLOP:

125338763(Arhgap35)

NCAR:

124966409

MMMA:

107151321(Arhgap35)

OCU:

100356673

OPI:	101535885(ARHGAP35)

TUP:	102497739(ARHGAP35)

GVR:	103592989(ARHGAP35)

CFA:	403543(ARHGAP35)

CLUD:

112645253(ARHGAP35)

VVP:	112931297(ARHGAP35)

VLG:	121485731(ARHGAP35)

NPO:	129499957(ARHGAP35)

AML:	100470620(ARHGAP35)

UMR:	103657074(ARHGAP35)

UAH:	113243384(ARHGAP35)

UAR:	123776341(ARHGAP35)

ELK:

111160649

LLV:

125088515

MPUF:

101671594(ARHGAP35)

MNP:	132005749(ARHGAP35)

MLK:	131818622(ARHGAP35)

NVS:	122911908(ARHGAP35)

ORO:	101369017(ARHGAP35)

EJU:	114197082(ARHGAP35)

ZCA:	113935486(ARHGAP35)

MLX:	117998186(ARHGAP35)

NSU:	110572924(ARHGAP35)

LWW:	102736111(ARHGAP35)

FCA:	101089912(ARHGAP35)

PYU:	121018669(ARHGAP35)

PCOO:

112850754(ARHGAP35)

PBG:	122494910(ARHGAP35)

PVIV:

125152865(ARHGAP35)

LRUF:

124510988

PTG:	102961807(ARHGAP35)

PPAD:

109253182(ARHGAP35)

PUC:

125915320

AJU:

106973631

HHV:	120241560(ARHGAP35)

BTA:	540310(ARHGAP35)

BOM:	102280880(ARHGAP35)

BIU:	109572253(ARHGAP35)

BBUB:

102403710(ARHGAP35)

BBIS:

104997731(ARHGAP35)

CHX:	102177274(ARHGAP35)

OAS:	101117354(ARHGAP35)

BTAX:

128064183(ARHGAP35)

ODA:	120872238(ARHGAP35)

CCAD:

122421710(ARHGAP35)

MBEZ:

129546625(ARHGAP35)

SSC:	100514580(ARHGAP35)

CFR:	102513779(ARHGAP35)

CBAI:

105062555(ARHGAP35)

CDK:	105104034(ARHGAP35)

VPC:	102531634(ARHGAP35)

BACU:

102999122(ARHGAP35)

BMUS:

118884788(ARHGAP35)

LVE:	103089007(ARHGAP35)

OOR:	101277261(ARHGAP35)

DLE:	111180700(ARHGAP35)

PCAD:

102991062(ARHGAP35)

PSIU:

116743624(ARHGAP35)

NASI:

112415395(ARHGAP35)

ECB:	100065944(ARHGAP35)

EPZ:	103560716(ARHGAP35)

EAI:	106845164(ARHGAP35)

MYB:	102245860(ARHGAP35)

MYD:	102774025(ARHGAP35)

MMYO:

118652839(ARHGAP35)

MLF:	102427607(ARHGAP35)

PKL:	118706748(ARHGAP35)

EFUS:

103297688(ARHGAP35)

MNA:	107540055(ARHGAP35)

DRO:	112312950(ARHGAP35)

SHON:

118996042(ARHGAP35)

AJM:	119056620(ARHGAP35)

PDIC:

114511248(ARHGAP35)

PHAS:

123822897(ARHGAP35)

MMF:	118638452(ARHGAP35)

PPAM:

129082880(ARHGAP35)

HAI:	109372218(ARHGAP35)

RFQ:	117035645(ARHGAP35)

PALE:

102898992(ARHGAP35)

PGIG:

120617895(ARHGAP35)

PVP:	105297317(ARHGAP35)

RAY:	107516007(ARHGAP35)

MJV:	108398868(ARHGAP35) 118969433

TOD:	119249479(ARHGAP35)

SARA:

101554838(ARHGAP35)

SETR:

126028192(ARHGAP35)

LAV:	100667574(ARHGAP35)

TMU:

101340735

ETF:	101639130(ARHGAP35)

DNM:	101419952(ARHGAP35)

MDO:	100016706(ARHGAP35)

GAS:	123239989(ARHGAP35)

SHR:	100935037(ARHGAP35)

AFZ:

127556261

PCW:	110202375(ARHGAP35)

OAA:	100079765(ARHGAP35)

GGA:	425730(ARHGAP35)

PCOC:

116241216(ARHGAP35)

MGP:	104916818(ARHGAP35)

CJO:	107307186(ARHGAP35)

LMUT:

125687530(ARHGAP35)

NMEL:

110391622(ARHGAP35)

ACYG:

106029337(ARHGAP35)

CATA:

118261626(ARHGAP35)

AFUL:

116501544(ARHGAP35)

TGU:	115490567(ARHGAP35)

LSR:	110481240(ARHGAP35)

SCAN:

103825048(ARHGAP35)

PMOA:

120511771(ARHGAP35)

OTC:	121342278(ARHGAP35)

PRUF:

121365350(ARHGAP35)

GFR:	102031981(ARHGAP35)

FAB:	101819462(ARHGAP35)

OMA:	130263351(ARHGAP35)

PHI:	102114087(ARHGAP35)

PMAJ:

107199356(ARHGAP35)

ETL:	114071940(ARHGAP35)

SVG:	106864385(ARHGAP35)

MMEA:

130586711(ARHGAP35)

FPG:	101924201(ARHGAP35)

FCH:	102055583(ARHGAP35)

CLV:	102089656(ARHGAP35)

EGZ:	104124255(ARHGAP35)

NNI:	104012641(ARHGAP35)

PCRI:

104032963(ARHGAP35)

PLET:

104627151(ARHGAP35)

EHS:	104506769(ARHGAP35)

PCAO:

104042594(ARHGAP35)

ACUN:

113490701(ARHGAP35)

TALA:

104359506(ARHGAP35)

PADL:

103922246(ARHGAP35)

AFOR:

103900928(ARHGAP35)

ACHC:

115338290 115338291

HALD:

104314025(ARHGAP35)

HLE:	104831524(ARHGAP35)

AGEN:

126037085

CCRI:

104165580(ARHGAP35)

CSTI:

104556313(ARHGAP35)

CMAC:

104484802(ARHGAP35)

MUI:	104538256(ARHGAP35)

BREG:

104632441(ARHGAP35)

FGA:	104083245(ARHGAP35)

GSTE:

104255548(ARHGAP35)

LDI:	104351657(ARHGAP35)

MNB:	103775302(ARHGAP35)

OHA:	104332218(ARHGAP35)

NNT:	104409272(ARHGAP35)

SHAB:

115603244(ARHGAP35)

DPUB:

104306277(ARHGAP35)

PGUU:

104461028(ARHGAP35)

ACAR:

104519859(ARHGAP35)

CPEA:

104394979(ARHGAP35)

CVF:	104282173(ARHGAP35)

RTD:	128901620(ARHGAP35)

CUCA:

104066129(ARHGAP35)

TEO:	104382930(ARHGAP35)

AAM:	106488006(ARHGAP35)

AROW:

112963741(ARHGAP35)

DNE:	112982420(ARHGAP35)

SCAM:

104147544(ARHGAP35)

ASN:	102373593(ARHGAP35)

AMJ:	102564417(ARHGAP35)

PSS:	102456198(ARHGAP35)

CMY:	102940259(ARHGAP35)

CCAY:

125628026(ARHGAP35)

DCC:	119847135(ARHGAP35)

CPIC:

101934187(ARHGAP35)

TST:	117889132(ARHGAP35)

CABI:

116828343(ARHGAP35)

MRV:	120388613(ARHGAP35)

ACS:	100562182(arhgap35)

ASAO:

132781683(ARHGAP35)

PVT:	110075631(ARHGAP35)

SUND:

121916042(ARHGAP35)

PBI:	103053947(ARHGAP35)

PMUR:

107291936(ARHGAP35)

CTIG:

120299806(ARHGAP35)

TSR:	106557251(ARHGAP35)

PGUT:

117677755(ARHGAP35)

APRI:

131204307(ARHGAP35)

PTEX:

113446052(ARHGAP35)

NSS:	113428073(ARHGAP35)

VKO:	123026124(ARHGAP35)

PMUA:

114603283(ARHGAP35)

PRAF:

128420280(ARHGAP35)

ZVI:	118087797(ARHGAP35)

HCG:	128332715(ARHGAP35)

GJA:	107121227(ARHGAP35)

STOW:

125434711(ARHGAP35)

EMC:	129343128(ARHGAP35)

XLA:	108700189(arhgap35.S) 414634(arhgap35.L)

XTR:	100498460(arhgap35)

NPR:	108803391(ARHGAP35)

RTEM:

120914390(ARHGAP35)

BBUF:

121009291(ARHGAP35)

BGAR:

122923868(ARHGAP35)

MUO:	115480997(ARHGAP35)

GSH:	117364529(ARHGAP35)

DRE:	100004299 564565(arhgap35)

SRX:	107724951 107726507 107734134 107746386

SANH:

107661244 107663410 107670284 107699836

SGH:	107574404 107592666 107596120 107599225

CCAR:

109047035 109047037 109085194

CAUA:

113058590 113076896 113115283

CGIB:

127957933 127972810 128004066 128028756

PTET:

122345429(arhgap35b) 122359443(arhgap35a)

LROH:

127164967(arhgap35b) 127177429(arhgap35a)

OMC:	131520746(arhgap35a) 131540741(arhgap35b)

PPRM:

120469844(arhgap35b) 120478739(arhgap35a)

RKG:	130072657(arhgap35b) 130095737(arhgap35a)

MAMB:

125248474(arhgap35a) 125266347(arhgap35b)

CIDE:

127495016 127512525

MASI:

127421882 127427807 127429541 127435089

TROS:

130564409(arhgap35a) 130571013(arhgap35b)

TDW:	130419088(arhgap35b) 130428102(arhgap35a)

MANU:

129437711(arhgap35a) 129440421(arhgap35b)

IPU:	108260288(arhgap35b) 108277872(arhgap35a)

IFU:	128603193(arhgap35b) 128620974(arhgap35a)

PHYP:

113531162 113539222(arhgap35)

SMEO:

124379217(arhgap35b) 124394446(arhgap35a)

TFD:	113643591(arhgap35a) 113662913(arhgap35b)

TVC:	132840740(arhgap35b) 132857647(arhgap35a)

AMEX:

103022018(arhgap35) 103022019

CMAO:

118803164(arhgap35a) 118814482(arhgap35b)

EEE:	113578658 113589130

CHAR:

105901059(arhgap35b) 105901528(arhgap35a)

TRU:	101068709 101070980(arhgap35)

TFS:	130535576(arhgap35a) 130537270(arhgap35b)

TNG:	GSTEN00014827G001 GSTEN00022182G001

LCO:	104919724 109140718(arhgap35)

NCC:	104954445 104956820(arhgap35)

TBEN:

117468868(arhgap35b) 117470507(arhgap35a)

CGOB:

115017573(arhgap35) 115018668

PGEO:

117457348(arhgap35a) 117458387(arhgap35b)

GACU:

117538458(arhgap35b) 117552195(arhgap35a)

EMAC:

134871749(arhgap35b) 134880144(arhgap35a)

ELY:	117259866(arhgap35a) 117267374(arhgap35b)

EFO:	125888218(arhgap35a) 125897762

PLEP:

121943717(arhgap35a) 121952439(arhgap35b)

SLUC:

116047734(arhgap35a) 116064724(arhgap35b)

ECRA:

117942163(arhgap35a) 117955033(arhgap35b)

ESP:	116678507(arhgap35) 116700588

PFLV:

114553094(arhgap35) 114567288

GAT:	120817405(arhgap35a) 120822789(arhgap35b)

PPUG:

119207156(arhgap35a) 119215046(arhgap35b)

AFB:	129101825(arhgap35a) 129113583(arhgap35b)

CLUM:

117741271(arhgap35a) 117743170(arhgap35b)

PSWI:

130209694(arhgap35b) 130210282(arhgap35a)

MSAM:

119882678(arhgap35a) 119895241(arhgap35b)

SCHU:

122879627(arhgap35a) 122888800(arhgap35b)

CUD:	121516502(arhgap35a) 121518692(arhgap35b)

ALAT:

119030780(arhgap35b) 119032475(arhgap35a)

MZE:	101470472(arhgap35) 101485265

ONL:	100690580(arhgap35) 100710886

OAU:	116314726(arhgap35a) 116330313(arhgap35b)

OLA:	101164082(arhgap35) 101169478

OML:	112142439(arhgap35b) 112149146(arhgap35a)

CSAI:

133441762(arhgap35a) 133459714(arhgap35b)

XMA:	102225731 102229863(arhgap35)

XCO:	114153331 114161369(arhgap35)

XHE:	116728375 116737340(arhgap35)

PRET:

103474623(arhgap35) 103475743

PFOR:

103133990 103136269(arhgap35)

PLAI:

106936925 106957919(arhgap35)

PMEI:

106919088 106934151(arhgap35)

GAF:	122833242(arhgap35a) 122844629(arhgap35b)

PPRL:

129359458(arhgap35a) 129368427(arhgap35b)

CVG:	107094177(arhgap35) 107101005

CTUL:

119790934(arhgap35b) 119792106(arhgap35a)

GMU:	124876380(arhgap35b) 124883753(arhgap35a)

NFU:	107380300(arhgap35) 107386538

KMR:	108243519(arhgap35a) 108247599(arhgap35b)

ALIM:

106516396 106532361

NWH:	119410619(arhgap35a) 119420669(arhgap35b)

AOCE:

111578690(arhgap35) 111579850

MCEP:

125012989(arhgap35a) 125020729(arhgap35b)

CSEM:

103378091(arhgap35) 103395548

POV:	109628568 109630196(arhgap35)

SSEN:

122773142(arhgap35a) 122779482(arhgap35b)

HHIP:

117773015(arhgap35a) 117773977(arhgap35b)

HSP:	118105733(arhgap35a) 118121742(arhgap35b)

SMAU:

118298963(arhgap35a) 118300369(arhgap35b)

LCF:	108893569(arhgap35b) 108900812(arhgap35a)

SDU:	111234595 111238883(arhgap35)

SLAL:

111653956 111656009(arhgap35)

XGL:	120791668(arhgap35a) 120802637(arhgap35b)

HCQ:	109512524 109526341(arhgap35)

SSCV:

125972421 125981714

SBIA:

133491869(arhgap35b) 133504429(arhgap35a)

PEE:	133404938(arhgap35a) 133416209(arhgap35b)

PTAO:

133466916(arhgap35b) 133482638(arhgap35a)

BPEC:

110154088(arhgap35) 110168102

MALB:

109959463 109973527(arhgap35)

BSPL:

114867703(arhgap35a) 114869106(arhgap35b)

SJO:	128360848(arhgap35a) 128370840(arhgap35b)

SASA:

106567838 106603369 106612372

STRU:

115149012 115154473 115162991 115205951

OTW:	112242721 112257727 112265084 112266677

OMY:	110503497 110507431(arhgap35a) 110533776 110537346

OGO:	123993060(arhgap35a) 123999906 124005921 124009357

ONE:	115105672 115135788 115137078 115141448

OKI:	109884589 109891781 109905426(arhgap35)

OKE:	118385905 118390210 118391799 118397137

SALP:

111949633 111950539 111960610 111980814

SNH:	120018400(arhgap35a) 120029004 120045116 120056546

CCLU:

121560279 121567386 121573672 121579982

ELS:	105012147(arhgap35) 105026008

SFM:	108932394(arhgap35) 108934386

PKI:	111844867(arhgap35)

AANG:

118208896(arhgap35a)

LOC:	102689375(arhgap35)

PSPA:

121304876 121308036

ARUT:

117396267 117415622

PSEX:

120538662(arhgap35a)

LCM:	102359039(ARHGAP35)

CMK:	103190406(arhgap35a)

RTP:

109936791

CPLA:

122542814(arhgap35a)

HOC:	132836577(arhgap35a)

LERI:

129714158(arhgap35a)

BFO:

118432802

BBEL:

109462328

SPU:

588152

DME:	Dmel_CG32555(RhoGAPp190)

DER:

6550194

DSE:

6618102

DSI:	Dsimw501_GD17349(Dsim_GD17349)

DYA:	Dyak_GE15581

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DMO:	Dmoj_GI21536

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:	101895418 131800820

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ009693

CPII:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

AROA:

TCA:

DPA:

SOY:	115875407 115886328

AGRG:

ATD:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105382670 105392864

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM293220

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

DPX:	DAPPUDRAFT_309374

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

XEN:

AQU:

Reference

PMID:18829532

Authors

Shen CH, Chen HY, Lin MS, Li FY, Chang CC, Kuo ML, Settleman J, Chen RH

Title

Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion.

Journal

Cancer Res 68:7779-87 (2008)
DOI:10.1158/0008-5472.CAN-08-0997

Sequence

[hsa:2909]

Reference

PMID:1894621

Authors

LeClerc S, Palaniswami R, Xie BX, Govindan MV

Title

Molecular cloning and characterization of a factor that binds the human glucocorticoid receptor gene and represses its expression.

Journal

J Biol Chem 266:17333-40 (1991)

Sequence

[hsa:2909]

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Gene (1886)   
   KEGG GENES (703)   
   KEGG MGENES (649)   
   RefGene (531)   
   OC (3)   
Literature (2)   
   PubMed (2)   
All databases (1899)   

Download RDF

DBGET integrated database retrieval system