KEGG ORTHOLOGY: K05868

ORTHOLOGY: K05868

Entry

K05868                      KO

Symbol

CCNB1

Name

G2/mitotic-specific cyclin-B1

Pathway

map04068

FoxO signaling pathway

map04110

Cell cycle

map04114

Oocyte meiosis

map04115

p53 signaling pathway

map04218

Cellular senescence

map04914

Progesterone-mediated oocyte maturation

map05170

Human immunodeficiency virus 1 infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K05868  CCNB1; G2/mitotic-specific cyclin-B1
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K05868  CCNB1; G2/mitotic-specific cyclin-B1
   04114 Oocyte meiosis
    K05868  CCNB1; G2/mitotic-specific cyclin-B1
   04115 p53 signaling pathway
    K05868  CCNB1; G2/mitotic-specific cyclin-B1
   04218 Cellular senescence
    K05868  CCNB1; G2/mitotic-specific cyclin-B1
09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K05868  CCNB1; G2/mitotic-specific cyclin-B1
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05868  CCNB1; G2/mitotic-specific cyclin-B1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins
    K05868  CCNB1; G2/mitotic-specific cyclin-B1
   03036 Chromosome and associated proteins
    K05868  CCNB1; G2/mitotic-specific cyclin-B1
DNA replication proteins [BR:ko03032]
Eukaryotic type
  DNA Replication Termination Factors
   Prevention of re-replication factors
    K05868  CCNB1; G2/mitotic-specific cyclin-B1
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Centrosome formation proteins
   Cyclins
    K05868  CCNB1; G2/mitotic-specific cyclin-B1

Other DBs

TC:

1.I.1.1

Genes

HSA:	891(CCNB1)

PTR:	461835(CCNB1)

PPS:	100992692(CCNB1)

GGO:	101123850(CCNB1)

PON:	100448656(CCNB1)

NLE:	100607012(CCNB1)

HMH:	116462484(CCNB1)

MCC:	699504(CCNB1)

MCF:	102122330(CCNB1)

MTHB:

126956539

MNI:	105475199(CCNB1)

CSAB:

103222804(CCNB1)

CATY:

105599256(CCNB1)

PANU:

101007909(CCNB1)

TGE:	112625921(CCNB1)

MLEU:

105543385(CCNB1)

RRO:	104675626(CCNB1)

RBB:	108541164(CCNB1)

TFN:	117065209(CCNB1)

PTEH:

111539895(CCNB1)

CANG:

105524206(CCNB1) 105526619

CJC:	100388085 100391291(CCNB1)

SBQ:	101049539 101052973(CCNB1)

CIMI:

108303636(CCNB1) 108304329

CSYR:

103252110

MMUR:

105881287(CCNB1)

LCAT:

123648319(CCNB1)

PCOQ:

105826606(CCNB1)

OGA:	100944047 100946063(CCNB1) 100953192 100966515

MMU:	268697(Ccnb1) 434175(Ccnb1-ps)

MCAL:

110307934(Ccnb1)

MPAH:

110328828(Ccnb1)

RNO:	25203(Ccnb1)

MCOC:

116083582(Ccnb1)

ANU:	117717125 117723665(Ccnb1)

MUN:	110566170(Ccnb1)

CGE:	100770842(Ccnb1)

MAUA:

101830316 101836169(Ccnb1)

PROB:

127220973(Ccnb1)

PLEU:

114703855(Ccnb1)

MORG:

121455799(Ccnb1)

MFOT:

126492506 126512615

AAMP:

119805267 119810462(Ccnb1)

NGI:	103738717(Ccnb1)

HGL:	101700598 101719153(Ccnb1)

CPOC:

100720222 100730790(Ccnb1)

CCAN:

109685702(Ccnb1)

DORD:

105998647

DSP:	122106167 122117245(Ccnb1)

PLOP:

125367827(Ccnb1)

NCAR:

124987022

MMMA:

107139435(Ccnb1)

OCU:

100338989

OPI:	101518790(CCNB1)

TUP:	102481989(CCNB1) 102498982

GVR:	103602744(CCNB1)

CFA:	487020 608420(CCNB1)

CLUD:

112660631(CCNB1) 125753218

VVP:	112921925 112935841(CCNB1)

VLG:	121474853 121496637(CCNB1)

NPO:	129495258 129497456 129509383 129510308 129514214(CCNB1)

AML:	100484338(CCNB1)

UMR:	103663615(CCNB1)

UAH:	113255260(CCNB1)

UAR:	123800258(CCNB1)

ELK:	111139031 111142448 111155277

LLV:	125100785 125100986 125107793

MPUF:

101683116(CCNB1) 101691234

MNP:	132027981 132028696(CCNB1)

MLK:	131832262 131832312(CCNB1)

NVS:	122890497 122918883(CCNB1)

ORO:	101375762(CCNB1)

EJU:	114198232(CCNB1)

ZCA:	113929111(CCNB1) 118356724

MLX:	118002147 118016867(CCNB1)

NSU:	110589801(CCNB1) 110590615

LWW:	102738490(CCNB1)

FCA:	101086284(CCNB1) 102900567

PYU:	121014916(CCNB1)

PCOO:

112861113(CCNB1)

PBG:	122468704 122485605(CCNB1)

PVIV:

125167452 125177162(CCNB1)

LRUF:

124502384

PTG:	102952704(CCNB1)

PPAD:

109275051(CCNB1)

PUC:	125911501 125935703

AJU:

106977069

HHV:	120247955(CCNB1)

BTA:	132345077 327679(CCNB1)

BOM:	102264536(CCNB1)

BIU:	109575025(CCNB1)

BBUB:

102413044(CCNB1)

BBIS:

104998440(CCNB1)

CHX:	102187875 102188170(CCNB1)

OAS:	101120694(CCNB1) 114117819

BTAX:

128066149(CCNB1) 128066902

ODA:	120879607(CCNB1)

CCAD:

122434837 122454476(CCNB1)

MBEZ:

129551652 129553034(CCNB1) 129553550

SSC:	397662(CCNB1)

CFR:	102522147(CCNB1)

CBAI:

105064414(CCNB1)

CDK:	105084760(CCNB1)

VPC:	102533213(CCNB1)

BACU:

103006271(CCNB1)

BMUS:

118891743(CCNB1) 118894457

LVE:	103069657(CCNB1)

OOR:	101286536(CCNB1)

DLE:	111163020(CCNB1)

PCAD:

102980273(CCNB1) 102995973 112064309

PSIU:

116750525 116752171(CCNB1) 116752899

NASI:

112407039(CCNB1)

ECB:	100050093(CCNB1)

EPZ:	103567186(CCNB1)

EAI:	106840139(CCNB1)

MYB:	102243790(CCNB1)

MYD:	102753675(CCNB1)

MMYO:

118656280(CCNB1)

MLF:	102426745(CCNB1)

PKL:	118702653(CCNB1)

EFUS:

103305163(CCNB1)

MNA:	107537801(CCNB1)

DRO:	112321071(CCNB1)

SHON:

118998590(CCNB1)

AJM:	119039990(CCNB1)

PDIC:

114507558(CCNB1)

PHAS:

123824694(CCNB1)

MMF:	118641687(CCNB1)

PPAM:

129074428(CCNB1)

HAI:	109375671(CCNB1)

RFQ:	117022183 117024444(CCNB1)

PALE:

102880158(CCNB1)

PGIG:

120608250(CCNB1)

PVP:	105309333(CCNB1)

RAY:	107498727(CCNB1)

MJV:	108406891(CCNB1)

TOD:	119260871(CCNB1) 119260933

SARA:

101558427(CCNB1)

SETR:

126001860(CCNB1)

LAV:	100654684(CCNB1)

TMU:	101347242 101354738

ETF:	101654399(CCNB1) 101659025

DNM:	101437315(CCNB1)

MDO:	100019387(CCNB1)

GAS:	123251651(CCNB1)

SHR:	100925753(CCNB1)

AFZ:

127558326

PCW:	110216613(CCNB1)

OAA:	100083344(CCNB1)

NMEL:

110389467(CCNB1)

ACYG:

106042079(CCNB1)

CATA:

118251456(CCNB1)

ACHL:

103808424

MMEA:

130572228

FPG:	101918655(CCNB1)

FCH:	102046409(CCNB1)

CLV:	102098298(CCNB1)

EGZ:	104124904(CCNB1)

NNI:	104009114(CCNB1)

PCRI:

104024662(CCNB1)

PLET:

104620335(CCNB1)

EHS:

104503403

PCAO:

104040022(CCNB1)

ACUN:

113489650(CCNB1)

TALA:

104363127(CCNB1)

PADL:

103919772(CCNB1)

AFOR:

103893417(CCNB1)

ACHC:

115336844(CCNB1)

HALD:

104310543(CCNB1)

HLE:	104839958(CCNB1)

AGEN:

126035998

CCRI:

104154952(CCNB1)

CMAC:

104476100

BREG:

104630409(CCNB1)

FGA:	104070020(CCNB1)

GSTE:

104250765(CCNB1)

LDI:

104351726

MNB:

103776965

OHA:	104331020(CCNB1)

NNT:

104400161

SHAB:

115619504(CCNB1)

PGUU:

104471056(CCNB1)

ACAR:

104531211(CCNB1)

CPEA:

104395685(CCNB1)

AVIT:

104278166

CVF:	104285783(CCNB1)

RTD:	128902420(CCNB1)

BRHI:

104496087(CCNB1)

AAM:

106484407

AROW:

112969927(CCNB1)

NPD:	112944417(CCNB1)

TGT:	104573176(CCNB1)

DNE:	112987113(CCNB1)

SCAM:

104152998(CCNB1)

ASN:	102381467(CCNB1)

AMJ:	102573326(CCNB1)

CPOO:

109307983(CCNB1)

GGN:	109297749(CCNB1)

PSS:	102448879(CCNB1)

CMY:	102946403(CCNB1)

CCAY:

125637181(CCNB1)

DCC:	119855475(CCNB1)

CPIC:

101931319(CCNB1)

TST:	117879312(CCNB1)

CABI:

116816065(CCNB1)

MRV:	120407688(CCNB1)

ACS:	100557278(ccnb1)

ASAO:

132767036(CCNB1)

PVT:	110073972(CCNB1)

SUND:

121921691(CCNB1)

PBI:	103056367(CCNB1)

PMUR:

107300638(CCNB1)

CTIG:

120303845(CCNB1)

TSR:	106551525(CCNB1)

PGUT:

117679257(CCNB1)

APRI:

131191349(CCNB1)

PTEX:

113445318(CCNB1)

NSS:	113413884(CCNB1)

VKO:	123031416(CCNB1)

PMUA:

114606547(CCNB1)

PRAF:

128423088(CCNB1)

ZVI:	118076807(CCNB1)

HCG:	128341741(CCNB1)

GJA:	107115487(CCNB1)

STOW:

125437215(CCNB1)

EMC:	129334612(CCNB1)

XLA:	108718066(ccnb1.L) 379888(ccnb1.2.L) 397742(ccnb1.2.S) 398163(ccnb1.S)

XTR:	100101736(ccnb1) 394726(ccnb1.2)

NPR:	108797587(CCNB1) 108802626

RTEM:

120928805(CCNB1) 120946138

BBUF:

120978746 120990719(CCNB1)

BGAR:

122922830 122922833 122929520(CCNB1)

MUO:	115463037(CCNB1)

GSH:	117353651(CCNB1)

DRE:	447870(ccnb1l) 58025(ccnb1)

SRX:	107730350 107738921 107740354

SANH:

107683704 107684352 107692469

SGH:	107572396 107595993 107596009 107600589

CCAR:

109054643 109080386 109097874

CAUA:

113049851 113083615 113118744

CGIB:

127958878 127977012 127993383

PTET:

122335717 122345540(ccnb1) 122362742 122362954

LROH:

127164692(ccnb1) 127180416

OMC:	131524382 131540050(ccnb1)

PPRM:

120472201 120477937

RKG:	130099675(ccnb1)

MAMB:

125254637 125267878(ccnb1)

CIDE:

127499394 127512710

MASI:

127419208 127434015 127455838

TROS:

130546854(ccnb1) 130562951

TDW:	130419371(ccnb1) 130435592

MANU:

129418870 129441168(ccnb1)

IPU:

108259996

IFU:	128603412(ccnb1)

PHYP:

113531034(ccnb1)

SMEO:

124379101(ccnb1)

TFD:	113641127(ccnb1)

TVC:	132840725(ccnb1)

AMEX:

103046107(ccnb1)

CMAO:

118814570(ccnb1)

EEE:	113588240(ccnb1)

CHAR:

105889007 105889018 105896340

TRU:	101074701(ccnb1) 115250234

TFS:	130517528(ccnb1)

TNG:	GSTEN00009252G001

LCO:	104922889(ccnb1)

TBEN:

117478734 117478736 117478900

CGOB:

115017178

PGEO:

117456102 117456242 117456246

GACU:

117558798 117558809

EMAC:

134868168(ccnb1)

ELY:	117269293(ccnb1)

EFO:	125905887(ccnb1)

PLEP:

121960227(ccnb1)

SLUC:

116034788(ccnb1)

ECRA:

117959794(ccnb1)

ESP:	116704379(ccnb1)

PFLV:

114570712(ccnb1)

GAT:	120832028(ccnb1)

PPUG:

119227097(ccnb1)

AFB:	129102142(ccnb1)

CLUM:

117740880(ccnb1)

PSWI:

130204995(ccnb1)

MSAM:

119914274(ccnb1)

SCHU:

122865794(ccnb1)

CUD:	121525620(ccnb1)

ALAT:

119030467(ccnb1)

MZE:	101483226(ccnb1)

ONL:	100708411(ccnb1)

OAU:	116324922(ccnb1)

OLA:	100049212(ccnb1)

OML:	112163494(ccnb1)

CSAI:

133455441

XMA:	102225497(ccnb1)

XCO:	114149794(ccnb1)

XHE:	116724562(ccnb1)

PRET:

103473942(ccnb1)

PFOR:

103154521(ccnb1)

PLAI:

106957659(ccnb1)

PMEI:

106920582(ccnb1)

GAF:	122847020(ccnb1)

PPRL:

129366441 129379660

CVG:	107083729(ccnb1)

CTUL:

119785172(ccnb1)

GMU:	124872201(ccnb1)

NFU:	107375104(ccnb1)

KMR:	108249280(ccnb1)

ALIM:

106534518(ccnb1)

NWH:	119424775(ccnb1)

AOCE:

111581445(ccnb1)

MCEP:

124997146(ccnb1)

CSEM:

103389033(ccnb1)

POV:	109640910(ccnb1)

SSEN:

122787055(ccnb1)

HHIP:

117771671(ccnb1)

HSP:	118098128(ccnb1)

SMAU:

118284987(ccnb1)

LCF:

108889030

SDU:	111221148(ccnb1)

SLAL:

111650108(ccnb1)

XGL:	120806840(ccnb1)

HCQ:	109527096(ccnb1)

SSCV:

125979790

SBIA:

133491096(ccnb1)

PEE:	133413645(ccnb1)

PTAO:

133465156(ccnb1)

BPEC:

110153549(ccnb1)

MALB:

109968695(ccnb1)

BSPL:

114867066(ccnb1)

SJO:	128380492(ccnb1)

SASA:

106562137 106563318(ccnb1) 106566708(CCNB1) 106587173

STRU:

115159595 115203015 115204043

OTW:	112220405 112230962(ccnb1) 112264049

OMY:	100136690 110506456 110523559

OGO:	124007134 124035070 124047880

ONE:	115101145(ccnb1) 115112810 115122380

OKI:	109867955 109874313 109895006

OKE:	118371683 118385328 118387510

SALP:

111961639 111963995 111969305

SNH:	120021267(ccnb1) 120025032 120026371

CCLU:

121541159(ccnb1) 121582280 121582538 121583457

ELS:	105015046(ccnb1)

SFM:	108929890(ccnb1)

PKI:	111835495(ccnb1)

AANG:

118212233(ccnb1)

LOC:	102696430(ccnb1)

PSPA:

121300671 121300682 121317063 121317073 121326955

ARUT:

117404009 117404010 117404013 117963921 117963946 117966120

PSEX:

120532555 120532556

LCM:	102359547(CCNB1) 102360112

CMK:	103177778 103177779

RTP:

109935081

CPLA:

122558191(ccnb1) 122565379

HOC:	132821397 132822355(ccnb1)

LERI:

129695062 129695077(ccnb1)

APLC:

SKO:

AALI:

ALAB:

ADR:

AFLR:

BBIF:

BVK:

BVAN:

BAFF:

BPYO:

BPAS:

FVI:

MGEN:

CGIG:

LHT:

LBD:

AGIF:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

SOY:

CSET:

AGB:

LDC:	111505018 111505027 111506183 111514192 111514907 111514908 111515408 111516618

OTU:

MJU:

ACOO:

DVT:

DCI:

HHAL:

FOC:

CSEC:

PJA:

PMOO:

HAME:

PTRU:

ESN:

MNZ:

LSM:

TCF:	131892342 131892343

PPOI:

119094426

SDM:

118179455

CEL:	CELE_H31G24.4(cyb-2.2) CELE_Y43E12A.1(cyb-2.1) CELE_ZC168.4(cyb-1)

CBR:	CBG_17647(Cbr-cyb-1)

CRQ:	GCK72_014901

LOA:	LOAG_17422

HRF:	124150100 124152832

HRJ:

CRG:

CANU:

OED:

PMAX:

MMER:

DPOL:

HSY:

TAD:	TRIADDRAFT_22525

AQU:

105313864

TET:	TTHERM_00293270

PTM:	GSPATT00026721001 GSPATT00036385001

» show all

Reference

PMID:2570636

Authors

Pines J, Hunter T

Title

Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2.

Journal

Cell 58:833-46 (1989)
DOI:10.1016/0092-8674(89)90936-7

Sequence

[hsa:891]

Reference

PMID:17592253

Authors

Miyazaki T, Arai S

Title

Two distinct controls of mitotic cdk1/cyclin B1 activity requisite for cell growth prior to cell division.

Journal

Cell Cycle 6:1419-25 (2007)
DOI:10.4161/cc.6.12.4409

All links

Ontology (4)   
   KEGG BRITE (3)   
   TC (1)   
Pathway (14)   
   KEGG PATHWAY (14)   
Gene (1979)   
   KEGG GENES (570)   
   KEGG MGENES (66)   
   RefGene (1334)   
   OC (9)   
Literature (2)   
   PubMed (2)   
All databases (1999)   

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