KEGG   PATHWAY: ko00190Help
Entry
ko00190                     Pathway                                

Name
Oxidative phosphorylation
Class
Metabolism; Energy metabolism
BRITE hierarchy
Pathway map
Oxidative phosphorylation
ko00190

All organismsOrtholog table
Module
M00142  
NADH:ubiquinone oxidoreductase, mitochondria [PATH:ko00190]
M00143  
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:ko00190]
M00144  
NADH:quinone oxidoreductase, prokaryotes [PATH:ko00190]
M00145  
NAD(P)H:quinone oxidoreductase, chloroplasts and cyanobacteria [PATH:ko00190]
M00146  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:ko00190]
M00147  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:ko00190]
M00148  
Succinate dehydrogenase (ubiquinone) [PATH:ko00190]
M00149  
Succinate dehydrogenase, prokaryotes [PATH:ko00190]
M00150  
Fumarate reductase, prokaryotes [PATH:ko00190]
M00151  
Cytochrome bc1 complex respiratory unit [PATH:ko00190]
M00152  
Cytochrome bc1 complex [PATH:ko00190]
M00153  
Cytochrome d ubiquinol oxidase [PATH:ko00190]
M00154  
Cytochrome c oxidase [PATH:ko00190]
M00155  
Cytochrome c oxidase, prokaryotes [PATH:ko00190]
M00156  
Cytochrome c oxidase, cbb3-type [PATH:ko00190]
M00157  
F-type ATPase, prokaryotes and chloroplasts [PATH:ko00190]
M00158  
F-type ATPase, eukaryotes [PATH:ko00190]
M00159  
V/A-type ATPase, prokaryotes [PATH:ko00190]
M00160  
V-type ATPase, eukaryotes [PATH:ko00190]
M00416  
Cytochrome aa3-600 menaquinol oxidase [PATH:ko00190]
M00417  
Cytochrome o ubiquinol oxidase [PATH:ko00190]
Disease
H00068  
Leber optic atrophy
H00473  
Mitochondrial respiratory chain deficiencies (MRCD)
H00920  
Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis
H01177  
Infantile bilateral striatal necrosis (IBSN)
H01200  
Fatal infantile cardioencephalomyopathy
H01222  
Cowden-like syndrome
H01347  
MELAS Syndrome
H01354  
Leigh syndrome
H01355  
Kearns-Sayre Syndrome
H01356  
Myoclonic Epilepsy and Ragged-Red Fiber Disease
H01363  
NARP syndrome
H01365  
Leber hereditary optic neuropathy and dystonia (LDYT)
H01368  
Cytochrome c oxidase (COX) deficiency
H01369  
ATP synthase deficiency
Orthology
K00329  
NADH dehydrogenase [EC:1.6.5.3]
K00330  
NADH-quinone oxidoreductase subunit A [EC:1.6.5.3]
K00331  
NADH-quinone oxidoreductase subunit B [EC:1.6.5.3]
K00332  
NADH-quinone oxidoreductase subunit C [EC:1.6.5.3]
K00333  
NADH-quinone oxidoreductase subunit D [EC:1.6.5.3]
K13378  
NADH-quinone oxidoreductase subunit C/D [EC:1.6.5.3]
K13380  
NADH-quinone oxidoreductase subunit B/C/D [EC:1.6.5.3]
K00334  
NADH-quinone oxidoreductase subunit E [EC:1.6.5.3]
K00335  
NADH-quinone oxidoreductase subunit F [EC:1.6.5.3]
K00336  
NADH-quinone oxidoreductase subunit G [EC:1.6.5.3]
K00337  
NADH-quinone oxidoreductase subunit H [EC:1.6.5.3]
K00338  
NADH-quinone oxidoreductase subunit I [EC:1.6.5.3]
K00339  
NADH-quinone oxidoreductase subunit J [EC:1.6.5.3]
K00340  
NADH-quinone oxidoreductase subunit K [EC:1.6.5.3]
K00341  
NADH-quinone oxidoreductase subunit L [EC:1.6.5.3]
K00342  
NADH-quinone oxidoreductase subunit M [EC:1.6.5.3]
K15863  
NADH-quinone oxidoreductase subunit L/M [EC:1.6.5.3]
K00343  
NADH-quinone oxidoreductase subunit N [EC:1.6.5.3]
K05572  
NAD(P)H-quinone oxidoreductase subunit 1 [EC:1.6.5.3]
K05573  
NAD(P)H-quinone oxidoreductase subunit 2 [EC:1.6.5.3]
K05574  
NAD(P)H-quinone oxidoreductase subunit 3 [EC:1.6.5.3]
K05575  
NAD(P)H-quinone oxidoreductase subunit 4 [EC:1.6.5.3]
K05576  
NAD(P)H-quinone oxidoreductase subunit 4L [EC:1.6.5.3]
K05577  
NAD(P)H-quinone oxidoreductase subunit 5 [EC:1.6.5.3]
K05578  
NAD(P)H-quinone oxidoreductase subunit 6 [EC:1.6.5.3]
K05579  
NAD(P)H-quinone oxidoreductase subunit H [EC:1.6.5.3]
K05580  
NAD(P)H-quinone oxidoreductase subunit I [EC:1.6.5.3]
K05581  
NAD(P)H-quinone oxidoreductase subunit J [EC:1.6.5.3]
K05582  
NAD(P)H-quinone oxidoreductase subunit K [EC:1.6.5.3]
K05583  
NAD(P)H-quinone oxidoreductase subunit L [EC:1.6.5.3]
K05584  
NAD(P)H-quinone oxidoreductase subunit M [EC:1.6.5.3]
K05585  
NAD(P)H-quinone oxidoreductase subunit N [EC:1.6.5.3]
K05586  
bidirectional [NiFe] hydrogenase diaphorase subunit [EC:1.6.5.3]
K05587  
bidirectional [NiFe] hydrogenase diaphorase subunit [EC:1.6.5.3]
K05588  
bidirectional [NiFe] hydrogenase diaphorase subunit [EC:1.6.5.3]
K03878  
NADH-ubiquinone oxidoreductase chain 1 [EC:1.6.5.3]
K03879  
NADH-ubiquinone oxidoreductase chain 2 [EC:1.6.5.3]
K03880  
NADH-ubiquinone oxidoreductase chain 3 [EC:1.6.5.3]
K03881  
NADH-ubiquinone oxidoreductase chain 4 [EC:1.6.5.3]
K03882  
NADH-ubiquinone oxidoreductase chain 4L [EC:1.6.5.3]
K03883  
NADH-ubiquinone oxidoreductase chain 5 [EC:1.6.5.3]
K03884  
NADH-ubiquinone oxidoreductase chain 6 [EC:1.6.5.3]
K03934  
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.99.3 1.6.5.3]
K03935  
NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.99.3 1.6.5.3]
K03936  
NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.99.3 1.6.5.3]
K03937  
NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938  
NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939  
NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940  
NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.99.3 1.6.5.3]
K03941  
NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.99.3 1.6.5.3]
K03942  
NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.99.3 1.6.5.3]
K03943  
NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.99.3 1.6.5.3]
K03944  
NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955  
NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1
K03956  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353  
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351  
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03967  
NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968  
NADH dehydrogenase (ubiquinone) 1 subunit C2
K00356  
NADH dehydrogenase [EC:1.6.99.3]
K03885  
NADH dehydrogenase [EC:1.6.99.3]
K05903  
NADH dehydrogenase (quinone) [EC:1.6.99.5]
K00234  
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235  
succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236  
succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237  
succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00239  
succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00240  
succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00241  
succinate dehydrogenase cytochrome b556 subunit
K00242  
succinate dehydrogenase membrane anchor subunit
K00244  
fumarate reductase flavoprotein subunit [EC:1.3.5.4]
K00245  
fumarate reductase iron-sulfur subunit [EC:1.3.5.4]
K00246  
fumarate reductase subunit C
K00247  
fumarate reductase subunit D
K00411  
ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
K00412  
ubiquinol-cytochrome c reductase cytochrome b subunit
K00413  
ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00410  
ubiquinol-cytochrome c reductase cytochrome b/c1 subunit
K00414  
ubiquinol-cytochrome c reductase core subunit 1
K00415  
ubiquinol-cytochrome c reductase core subunit 2
K00416  
ubiquinol-cytochrome c reductase subunit 6
K00417  
ubiquinol-cytochrome c reductase subunit 7
K00418  
ubiquinol-cytochrome c reductase subunit 8
K00419  
ubiquinol-cytochrome c reductase subunit 9
K00420  
ubiquinol-cytochrome c reductase subunit 10
K03886  
menaquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.-]
K03887  
menaquinol-cytochrome c reductase cytochrome b subunit
K03888  
menaquinol-cytochrome c reductase cytochrome b/c subunit
K03889  
ubiquinol-cytochrome c reductase cytochrome c subunit
K03890  
ubiquinol-cytochrome c reductase iron-sulfur subunit
K03891  
ubiquinol-cytochrome c reductase cytochrome b subunit
K02301  
protoheme IX farnesyltransferase [EC:2.5.1.-]
K02257  
protoheme IX farnesyltransferase [EC:2.5.1.-]
K02300  
cytochrome o ubiquinol oxidase operon protein cyoD
K02277  
cytochrome c oxidase subunit IV [EC:1.9.3.1]
K02276  
cytochrome c oxidase subunit III [EC:1.9.3.1]
K02274  
cytochrome c oxidase subunit I [EC:1.9.3.1]
K15408  
cytochrome c oxidase subunit I+III [EC:1.9.3.1]
K02275  
cytochrome c oxidase subunit II [EC:1.9.3.1]
K02262  
cytochrome c oxidase subunit 3
K02256  
cytochrome c oxidase subunit 1 [EC:1.9.3.1]
K02261  
cytochrome c oxidase subunit 2
K02263  
cytochrome c oxidase subunit 4
K02264  
cytochrome c oxidase subunit 5a
K02265  
cytochrome c oxidase subunit 5b
K02266  
cytochrome c oxidase subunit 6a
K02267  
cytochrome c oxidase subunit 6b
K02268  
cytochrome c oxidase subunit 6c
K02269  
cytochrome c oxidase subunit 7
K02270  
cytochrome c oxidase subunit 7a
K02271  
cytochrome c oxidase subunit 7b
K02272  
cytochrome c oxidase subunit 7c
K02273  
cytochrome c oxidase subunit 8
K02258  
cytochrome c oxidase assembly protein subunit 11
K02259  
cytochrome c oxidase assembly protein subunit 15
K02260  
cytochrome c oxidase assembly protein subunit 17
K00404  
cytochrome c oxidase cbb3-type subunit I [EC:1.9.3.1]
K00405  
cytochrome c oxidase cbb3-type subunit II
K15862  
cytochrome c oxidase cbb3-type subunit I/II [EC:1.9.3.1]
K00407  
cytochrome c oxidase cbb3-type subunit IV
K00406  
cytochrome c oxidase cbb3-type subunit III
K02829  
cytochrome aa3-600 menaquinol oxidase subunit IV [EC:1.10.3.12]
K02828  
cytochrome aa3-600 menaquinol oxidase subunit III [EC:1.10.3.12]
K02827  
cytochrome aa3-600 menaquinol oxidase subunit I [EC:1.10.3.12]
K02826  
cytochrome aa3-600 menaquinol oxidase subunit II [EC:1.10.3.12]
K02299  
cytochrome o ubiquinol oxidase subunit III [EC:1.10.3.-]
K02298  
cytochrome o ubiquinol oxidase subunit I [EC:1.10.3.-]
K02297  
cytochrome o ubiquinol oxidase subunit II [EC:1.10.3.-]
K00425  
cytochrome d ubiquinol oxidase subunit I [EC:1.10.3.-]
K00426  
cytochrome d ubiquinol oxidase subunit II [EC:1.10.3.-]
K02111  
F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14]
K02112  
F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]
K02115  
F-type H+-transporting ATPase subunit gamma
K02113  
F-type H+-transporting ATPase subunit delta
K02114  
F-type H+-transporting ATPase subunit epsilon
K02108  
F-type H+-transporting ATPase subunit a
K02109  
F-type H+-transporting ATPase subunit b
K02110  
F-type H+-transporting ATPase subunit c
K02132  
F-type H+-transporting ATPase subunit alpha
K02133  
F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]
K02136  
F-type H+-transporting ATPase subunit gamma
K02134  
F-type H+-transporting ATPase subunit delta
K02135  
F-type H+-transporting ATPase subunit epsilon
K02137  
F-type H+-transporting ATPase subunit O
K02126  
F-type H+-transporting ATPase subunit a
K02127  
F-type H+-transporting ATPase subunit b
K02128  
F-type H+-transporting ATPase subunit c
K02138  
F-type H+-transporting ATPase subunit d
K02129  
F-type H+-transporting ATPase subunit e
K01549  
F-type H+-transporting ATP synthase subunit e
K02130  
F-type H+-transporting ATPase subunit f
K02139  
F-type H+-transporting ATPase subunit f
K02140  
F-type H+-transporting ATPase subunit g
K02131  
F-type H+-transporting ATPase subunit 6
K02141  
F-type H+-transporting ATPase subunit h
K02142  
F-type H+-transporting ATPase subunit j
K02143  
F-type H+-transporting ATPase subunit k
K02125  
F-type H+-transporting ATPase subunit 8
K02117  
V/A-type H+-transporting ATPase subunit A [EC:3.6.3.14]
K02118  
V/A-type H+-transporting ATPase subunit B
K02119  
V/A-type H+-transporting ATPase subunit C
K02120  
V/A-type H+-transporting ATPase subunit D
K02121  
V/A-type H+-transporting ATPase subunit E
K02122  
V/A-type H+-transporting ATPase subunit F
K02107  
V/A-type H+-transporting ATPase subunit G/H
K02123  
V/A-type H+-transporting ATPase subunit I
K02124  
V/A-type H+-transporting ATPase subunit K
K02145  
V-type H+-transporting ATPase subunit A [EC:3.6.3.14]
K02147  
V-type H+-transporting ATPase subunit B
K02148  
V-type H+-transporting ATPase subunit C
K02149  
V-type H+-transporting ATPase subunit D
K02150  
V-type H+-transporting ATPase subunit E
K02151  
V-type H+-transporting ATPase subunit F
K02152  
V-type H+-transporting ATPase subunit G
K02144  
V-type H+-transporting ATPase subunit H
K02154  
V-type H+-transporting ATPase subunit a
K02155  
V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661  
V-type H+-transporting ATPase 21kDa proteolipid subunit
K02146  
V-type H+-transporting ATPase subunit d
K02153  
V-type H+-transporting ATPase subunit e
K03662  
V-type H+-transporting ATPase S1 subunit
K01535  
H+-transporting ATPase [EC:3.6.3.6]
K01541  
H+/K+-exchanging ATPase [EC:3.6.3.10]
K01542  
H+/K+-exchanging ATPase alpha polypeptide [EC:3.6.3.10]
K01543  
H+/K+-exchanging ATPase beta polypeptide [EC:3.6.3.10]
K01544  
non-gastric H+/K+-exchanging ATPase [EC:3.6.3.10]
K01507  
inorganic pyrophosphatase [EC:3.6.1.1]
K15986  
manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1]
K06019  
pyrophosphatase PpaX [EC:3.6.1.1]
K15987  
K(+)-stimulated pyrophosphate-energized sodium pump [EC:3.6.1.1]
K11725  
phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.1.3.- 3.6.1.1]
K11726  
nucleosome-remodeling factor 38 kDa subunit [EC:3.6.1.1]
K00937  
polyphosphate kinase [EC:2.7.4.1]
Compound
C00001  
H2O
C00002  
ATP
C00003  
NAD+
C00004  
NADH
C00007  
Oxygen
C00008  
ADP
C00009  
Orthophosphate
C00013  
Diphosphate
C00042  
Succinate
C00061  
FMN
C00080  
H+
C00122  
Fumarate
C00390  
Ubiquinol
C00399  
Ubiquinone
C00524  
Cytochrome c
C00536  
Triphosphate
Reference
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
Reference
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)

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