KEGG   PATHWAY: ko00190Help
ko00190                     Pathway                                

Oxidative phosphorylation
Metabolism; Energy metabolism
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Pathway map
ko00190  Oxidative phosphorylation

Ortholog table
M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:ko00190]
M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:ko00190]
M00144  NADH:quinone oxidoreductase, prokaryotes [PATH:ko00190]
M00145  NAD(P)H:quinone oxidoreductase, chloroplasts and cyanobacteria [PATH:ko00190]
M00146  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:ko00190]
M00147  NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:ko00190]
M00148  Succinate dehydrogenase (ubiquinone) [PATH:ko00190]
M00149  Succinate dehydrogenase, prokaryotes [PATH:ko00190]
M00150  Fumarate reductase, prokaryotes [PATH:ko00190]
M00151  Cytochrome bc1 complex respiratory unit [PATH:ko00190]
M00152  Cytochrome bc1 complex [PATH:ko00190]
M00153  Cytochrome bd ubiquinol oxidase [PATH:ko00190]
M00154  Cytochrome c oxidase [PATH:ko00190]
M00155  Cytochrome c oxidase, prokaryotes [PATH:ko00190]
M00156  Cytochrome c oxidase, cbb3-type [PATH:ko00190]
M00157  F-type ATPase, prokaryotes and chloroplasts [PATH:ko00190]
M00158  F-type ATPase, eukaryotes [PATH:ko00190]
M00159  V/A-type ATPase, prokaryotes [PATH:ko00190]
M00160  V-type ATPase, eukaryotes [PATH:ko00190]
M00416  Cytochrome aa3-600 menaquinol oxidase [PATH:ko00190]
M00417  Cytochrome o ubiquinol oxidase [PATH:ko00190]
H00068  Leber hereditary optic atrophy (LHON)
H00473  Mitochondrial complex I deficiency
H00920  Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis
H01177  Infantile bilateral striatal necrosis (IBSN)
H01200  Fatal infantile cardioencephalomyopathy
H01347  MELAS Syndrome
H01354  Leigh syndrome
H01355  Kearns-Sayre syndrome
H01356  Myoclonic Epilepsy and Ragged-Red Fiber Disease
H01363  NARP syndrome
H01365  Leber hereditary optic neuropathy and dystonia (LDYT)
H01368  Cytochrome c oxidase (COX) deficiency
H01369  ATP synthase deficiency
H01904  Microphthalmia with linear skin defects (MLS) syndrome
H02005  Mitochondrial complex II deficiency
D09872  Bedaquiline (USAN/INN)
D09873  Bedaquiline fumarate (JAN/USAN)
K00329  NADH dehydrogenase [EC:]
K00330  NADH-quinone oxidoreductase subunit A [EC:]
K00331  NADH-quinone oxidoreductase subunit B [EC:]
K00332  NADH-quinone oxidoreductase subunit C [EC:]
K00333  NADH-quinone oxidoreductase subunit D [EC:]
K13378  NADH-quinone oxidoreductase subunit C/D [EC:]
K13380  NADH-quinone oxidoreductase subunit B/C/D [EC:]
K00334  NADH-quinone oxidoreductase subunit E [EC:]
K00335  NADH-quinone oxidoreductase subunit F [EC:]
K00336  NADH-quinone oxidoreductase subunit G [EC:]
K00337  NADH-quinone oxidoreductase subunit H [EC:]
K00338  NADH-quinone oxidoreductase subunit I [EC:]
K00339  NADH-quinone oxidoreductase subunit J [EC:]
K00340  NADH-quinone oxidoreductase subunit K [EC:]
K00341  NADH-quinone oxidoreductase subunit L [EC:]
K00342  NADH-quinone oxidoreductase subunit M [EC:]
K15863  NADH-quinone oxidoreductase subunit L/M [EC:]
K00343  NADH-quinone oxidoreductase subunit N [EC:]
K05572  NAD(P)H-quinone oxidoreductase subunit 1 [EC:]
K05573  NAD(P)H-quinone oxidoreductase subunit 2 [EC:]
K05574  NAD(P)H-quinone oxidoreductase subunit 3 [EC:]
K05575  NAD(P)H-quinone oxidoreductase subunit 4 [EC:]
K05576  NAD(P)H-quinone oxidoreductase subunit 4L [EC:]
K05577  NAD(P)H-quinone oxidoreductase subunit 5 [EC:]
K05578  NAD(P)H-quinone oxidoreductase subunit 6 [EC:]
K05579  NAD(P)H-quinone oxidoreductase subunit H [EC:]
K05580  NAD(P)H-quinone oxidoreductase subunit I [EC:]
K05581  NAD(P)H-quinone oxidoreductase subunit J [EC:]
K05582  NAD(P)H-quinone oxidoreductase subunit K [EC:]
K05583  NAD(P)H-quinone oxidoreductase subunit L [EC:]
K05584  NAD(P)H-quinone oxidoreductase subunit M [EC:]
K05585  NAD(P)H-quinone oxidoreductase subunit N [EC:]
K05586  bidirectional [NiFe] hydrogenase diaphorase subunit [EC:]
K05587  bidirectional [NiFe] hydrogenase diaphorase subunit [EC:]
K05588  bidirectional [NiFe] hydrogenase diaphorase subunit [EC:]
K03878  NADH-ubiquinone oxidoreductase chain 1 [EC:]
K03879  NADH-ubiquinone oxidoreductase chain 2 [EC:]
K03880  NADH-ubiquinone oxidoreductase chain 3 [EC:]
K03881  NADH-ubiquinone oxidoreductase chain 4 [EC:]
K03882  NADH-ubiquinone oxidoreductase chain 4L [EC:]
K03883  NADH-ubiquinone oxidoreductase chain 5 [EC:]
K03884  NADH-ubiquinone oxidoreductase chain 6 [EC:]
K03934  NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:]
K03935  NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:]
K03936  NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:]
K03937  NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938  NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939  NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940  NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:]
K03941  NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:]
K03942  NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:]
K03943  NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:]
K03944  NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955  NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1
K03956  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351  NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03967  NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968  NADH dehydrogenase (ubiquinone) 1 subunit C2
K00356  NADH dehydrogenase [EC:]
K03885  NADH dehydrogenase [EC:]
K00234  succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:]
K00235  succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:]
K00236  succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237  succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00239  succinate dehydrogenase / fumarate reductase, flavoprotein subunit [EC:]
K00240  succinate dehydrogenase / fumarate reductase, iron-sulfur subunit [EC:]
K00241  succinate dehydrogenase / fumarate reductase, cytochrome b subunit
K00242  succinate dehydrogenase / fumarate reductase, membrane anchor subunit
K18859  succinate dehydrogenase / fumarate reductase, subunit D
K18860  putative succinate dehydrogenase / fumarate reductase, subunit D
K00244  fumarate reductase flavoprotein subunit [EC:]
K00245  fumarate reductase iron-sulfur subunit [EC:]
K00246  fumarate reductase subunit C
K00247  fumarate reductase subunit D
K00411  ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:]
K00412  ubiquinol-cytochrome c reductase cytochrome b subunit
K00413  ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00410  ubiquinol-cytochrome c reductase cytochrome b/c1 subunit
K00414  ubiquinol-cytochrome c reductase core subunit 1
K00415  ubiquinol-cytochrome c reductase core subunit 2
K00416  ubiquinol-cytochrome c reductase subunit 6
K00417  ubiquinol-cytochrome c reductase subunit 7
K00418  ubiquinol-cytochrome c reductase subunit 8
K00419  ubiquinol-cytochrome c reductase subunit 9
K00420  ubiquinol-cytochrome c reductase subunit 10
K03886  menaquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.-]
K03887  menaquinol-cytochrome c reductase cytochrome b subunit
K03888  menaquinol-cytochrome c reductase cytochrome b/c subunit
K03889  ubiquinol-cytochrome c reductase cytochrome c subunit
K03890  ubiquinol-cytochrome c reductase iron-sulfur subunit
K03891  ubiquinol-cytochrome c reductase cytochrome b subunit
K02257  heme o synthase [EC:]
K02300  cytochrome o ubiquinol oxidase subunit IV
K02277  cytochrome c oxidase subunit IV [EC:]
K02276  cytochrome c oxidase subunit III [EC:]
K02274  cytochrome c oxidase subunit I [EC:]
K15408  cytochrome c oxidase subunit I+III [EC:]
K02275  cytochrome c oxidase subunit II [EC:]
K02262  cytochrome c oxidase subunit 3
K02256  cytochrome c oxidase subunit 1 [EC:]
K02261  cytochrome c oxidase subunit 2
K02263  cytochrome c oxidase subunit 4
K02264  cytochrome c oxidase subunit 5a
K02265  cytochrome c oxidase subunit 5b
K02266  cytochrome c oxidase subunit 6a
K02267  cytochrome c oxidase subunit 6b
K02268  cytochrome c oxidase subunit 6c
K02269  cytochrome c oxidase subunit 7
K02270  cytochrome c oxidase subunit 7a
K02271  cytochrome c oxidase subunit 7b
K02272  cytochrome c oxidase subunit 7c
K02273  cytochrome c oxidase subunit 8
K02258  cytochrome c oxidase assembly protein subunit 11
K02259  cytochrome c oxidase assembly protein subunit 15
K02260  cytochrome c oxidase assembly protein subunit 17
K00404  cytochrome c oxidase cbb3-type subunit I [EC:]
K00405  cytochrome c oxidase cbb3-type subunit II
K15862  cytochrome c oxidase cbb3-type subunit I/II [EC:]
K00407  cytochrome c oxidase cbb3-type subunit IV
K00406  cytochrome c oxidase cbb3-type subunit III
K02829  cytochrome aa3-600 menaquinol oxidase subunit IV [EC:]
K02828  cytochrome aa3-600 menaquinol oxidase subunit III [EC:]
K02827  cytochrome aa3-600 menaquinol oxidase subunit I [EC:]
K02826  cytochrome aa3-600 menaquinol oxidase subunit II [EC:]
K02299  cytochrome o ubiquinol oxidase subunit III
K02298  cytochrome o ubiquinol oxidase subunit I [EC:]
K02297  cytochrome o ubiquinol oxidase subunit II [EC:]
K00425  cytochrome bd ubiquinol oxidase subunit I [EC:]
K00426  cytochrome bd ubiquinol oxidase subunit II [EC:]
K00424  cytochrome bd-I ubiquinol oxidase subunit X [EC:]
K22501  cytochrome bd-II ubiquinol oxidase subunit AppX [EC:]
K02111  F-type H+-transporting ATPase subunit alpha [EC:]
K02112  F-type H+-transporting ATPase subunit beta [EC:]
K02115  F-type H+-transporting ATPase subunit gamma
K02113  F-type H+-transporting ATPase subunit delta
K02114  F-type H+-transporting ATPase subunit epsilon
K02108  F-type H+-transporting ATPase subunit a
K02109  F-type H+-transporting ATPase subunit b
K02110  F-type H+-transporting ATPase subunit c
K02132  F-type H+-transporting ATPase subunit alpha
K02133  F-type H+-transporting ATPase subunit beta [EC:]
K02136  F-type H+-transporting ATPase subunit gamma
K02134  F-type H+-transporting ATPase subunit delta
K02135  F-type H+-transporting ATPase subunit epsilon
K02137  F-type H+-transporting ATPase subunit O
K02126  F-type H+-transporting ATPase subunit a
K02127  F-type H+-transporting ATPase subunit b
K02128  F-type H+-transporting ATPase subunit c
K02138  F-type H+-transporting ATPase subunit d
K02129  F-type H+-transporting ATPase subunit e
K01549  F-type H+-transporting ATP synthase subunit e
K02130  F-type H+-transporting ATPase subunit f
K02139  F-type H+-transporting ATPase subunit f
K02140  F-type H+-transporting ATPase subunit g
K02131  F-type H+-transporting ATPase subunit 6
K02141  F-type H+-transporting ATPase subunit h
K02142  F-type H+-transporting ATPase subunit j
K02143  F-type H+-transporting ATPase subunit k
K02125  F-type H+-transporting ATPase subunit 8
K02117  V/A-type H+/Na+-transporting ATPase subunit A [EC:]
K02118  V/A-type H+/Na+-transporting ATPase subunit B
K02119  V/A-type H+/Na+-transporting ATPase subunit C
K02120  V/A-type H+/Na+-transporting ATPase subunit D
K02121  V/A-type H+/Na+-transporting ATPase subunit E
K02122  V/A-type H+/Na+-transporting ATPase subunit F
K02107  V/A-type H+/Na+-transporting ATPase subunit G/H
K02123  V/A-type H+/Na+-transporting ATPase subunit I
K02124  V/A-type H+/Na+-transporting ATPase subunit K
K02145  V-type H+-transporting ATPase subunit A [EC:]
K02147  V-type H+-transporting ATPase subunit B
K02148  V-type H+-transporting ATPase subunit C
K02149  V-type H+-transporting ATPase subunit D
K02150  V-type H+-transporting ATPase subunit E
K02151  V-type H+-transporting ATPase subunit F
K02152  V-type H+-transporting ATPase subunit G
K02144  V-type H+-transporting ATPase subunit H
K02154  V-type H+-transporting ATPase subunit a
K02155  V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661  V-type H+-transporting ATPase 21kDa proteolipid subunit
K02146  V-type H+-transporting ATPase subunit d
K02153  V-type H+-transporting ATPase subunit e
K03662  V-type H+-transporting ATPase S1 subunit
K01535  H+-transporting ATPase [EC:]
K01541  H+/K+-exchanging ATPase [EC:]
K01542  H+/K+-exchanging ATPase alpha polypeptide [EC:]
K01543  H+/K+-exchanging ATPase beta polypeptide [EC:]
K01544  non-gastric H+/K+-exchanging ATPase [EC:]
K01507  inorganic pyrophosphatase [EC:]
K15986  manganese-dependent inorganic pyrophosphatase [EC:]
K06019  pyrophosphatase PpaX [EC:]
K15987  K(+)-stimulated pyrophosphate-energized sodium pump [EC:]
K11725  phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.1.3.-]
K11726  nucleosome-remodeling factor 38 kDa subunit [EC:]
K00937  polyphosphate kinase [EC:]
K22468  polyphosphate kinase [EC:]
C00001  H2O
C00002  ATP
C00003  NAD+
C00004  NADH
C00007  Oxygen
C00008  ADP
C00009  Orthophosphate
C00013  Diphosphate
C00042  Succinate
C00061  FMN
C00080  H+
C00122  Fumarate
C00390  Ubiquinol
C00399  Ubiquinone
C00524  Cytochrome c
C00536  Triphosphate
Sazanov LA, Hinchliffe P.
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
Science 311:1430-6 (2006)
Hinchliffe P, Carroll J, Sazanov LA.
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
Biochemistry 45:4413-20 (2006)

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