KEGG   ORTHOLOGY: K00030Help
Entry
K00030                      KO                                     

Name
IDH3
Definition
isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
Pathway
ko00020  Citrate cycle (TCA cycle)
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01130  Biosynthesis of antibiotics
ko01200  Carbon metabolism
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Disease
H00527  Retinitis pigmentosa (RP)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    K00030  IDH3; isocitrate dehydrogenase (NAD+)
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00009  Citrate cycle (TCA cycle, Krebs cycle)
     K00030  IDH3; isocitrate dehydrogenase (NAD+)
    M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
     K00030  IDH3; isocitrate dehydrogenase (NAD+)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.41  isocitrate dehydrogenase (NAD+)
     K00030  IDH3; isocitrate dehydrogenase (NAD+)
BRITE hierarchy
Other DBs
RN: R00709
COG: COG0473
GO: 0004449
Genes
HSA: 3419(IDH3A) 3420(IDH3B) 3421(IDH3G)
PTR: 453565(IDH3A) 458048(IDH3B) 741179(IDH3G)
PPS: 100968720(IDH3B) 100972968(IDH3G) 100987648(IDH3A)
GGO: 101126919(IDH3G) 101135027(IDH3A) 101141517(IDH3B)
PON: 100172089(IDH3A) 100172344(IDH3B) 100436005(IDH3G)
NLE: 100590336(IDH3B) 100593540(IDH3G) 100606177(IDH3A)
MCC: 677715(IDH3A) 698558(IDH3G) 716726(IDH3B)
MCF: 101865050(IDH3A) 102124727(IDH3G) 102129545(IDH3B)
CSAB: 103215621(IDH3B) 103232801(IDH3G) 103245258(IDH3A)
RRO: 104661175(IDH3G) 104674376(IDH3A) 104674627(IDH3B)
RBB: 108514547 108524292(IDH3A) 108529987(IDH3B) 108535078(IDH3G)
CJC: 100403538(IDH3B) 100405727(IDH3G) 100413152(IDH3A)
SBQ: 101032511(IDH3G) 101041482 101043727 101050203(IDH3A) 101051785(IDH3B)
MMU: 15929(Idh3g) 170718(Idh3b) 243996(4933405O20Rik) 67834(Idh3a)
RNO: 100125384 103690168 114096(Idh3a) 25179(Idh3g) 94173(Idh3B)
CGE: 100751753(Idh3g) 100754480(Idh3a) 100771661(Idh3b) 100772968
NGI: 103726021(Idh3a) 103731201(Idh3g) 103751138(Idh3b)
HGL: 101706503(Idh3a) 101709094(Idh3b) 101721638(Idh3g)
CCAN: 109674406 109682388(Idh3a) 109692900(Idh3b) 109698474(Idh3g)
OCU: 100328743(IDH3G) 100338100(IDH3A) 100342113(IDH3B) 103351073
TUP: 102475641(IDH3G) 102479509(IDH3A) 102493633(IDH3B) 102494733
CFA: 477177(IDH3B) 479066(IDH3A) 481081(IDH3G)
AML: 100466084(IDH3B) 100473236 100482520(IDH3A) 100483295(IDH3G)
UMR: 103659417 103660316(IDH3A) 103674513(IDH3B) 103679698(IDH3G)
ORO: 101365002(IDH3A) 101378494(IDH3G) 101380358 101380671(IDH3B)
FCA: 101085721(IDH3A) 101086177 101099035(IDH3B) 102902308(IDH3G)
PTG: 102954160(IDH3G) 102955736(IDH3B) 102968859(IDH3A)
AJU: 106978422 106980169(IDH3B) 106988469(IDH3A) 106989688(IDH3G)
BTA: 282446(IDH3A) 613338(IDH3B) 614145(IDH3G)
BOM: 102269910(IDH3B) 102273099(IDH3G) 102281295(IDH3A)
BIU: 109555187(IDH3G) 109567214(IDH3B) 109575516(IDH3A)
PHD: 102318399(IDH3A) 102322009(IDH3G) 102324803(IDH3B)
CHX: 102172823(IDH3B) 102181480(IDH3G) 102181902(IDH3A)
OAS: 101104080(IDH3B) 101110910(IDH3G) 101120868(IDH3A)
SSC: 100157242(IDH3A) 100525850(IDH3G) 733641(IDH3B)
CFR: 102504528(IDH3A) 102504939(IDH3B) 102513449(IDH3G) 106731107
CDK: 105092226(IDH3A) 105096042(IDH3B) 105098707(IDH3G)
BACU: 102998515(IDH3B) 103016817(IDH3G) 103018652(IDH3A)
LVE: 103072517(IDH3B) 103087344(IDH3A) 103091109(IDH3G)
OOR: 101273087(IDH3B) 101277332(IDH3G) 101278784(IDH3A)
ECB: 100052969(IDH3B) 100057896(IDH3G) 100060114(IDH3A) 102148971
EAI: 106823126(IDH3B) 106825620(IDH3G) 106831328 106840824(IDH3A)
MYB: 102247279(IDH3A) 102248160(IDH3B) 102258465 102262688(IDH3G)
MYD: 102759311(IDH3A) 102760750(IDH3G) 102762142(IDH3B) 102771723
HAI: 109381453(IDH3A) 109384445(IDH3B) 109387447 109394340(IDH3G)
PALE: 102879783(IDH3B) 102885938(IDH3G) 102889641 102898135(IDH3A)
LAV: 100654370(IDH3G) 100660691(IDH3A) 100675574(IDH3B) 111751222
MDO: 100012825(IDH3A) 100017654(IDH3B) 100027983(IDH3G)
SHR: 100926332(IDH3A) 100926870(IDH3G) 100927370(IDH3B)
OAA: 100080286(IDH3G) 100082669(IDH3A)
GGA: 101751023 415362(IDH3A) 426573(IDH3B)
MGP: 100538992(IDH3B) 100549122(IDH3A)
CJO: 107306828(IDH3B) 107307385 107318544(IDH3A)
APLA: 101795551(IDH3A)
ACYG: 106033768(IDH3A) 106043186(IDH3B)
TGU: 100190682(IDH3A) 100224627(IDH3B)
GFR: 102031374(IDH3A) 102037020(IDH3B) 102037586
FAB: 101812942(IDH3B) 101821410(IDH3A)
PHI: 102101435(IDH3G) 102102008(IDH3A) 102102923(IDH3B)
PMAJ: 107199392 107199464(IDH3G) 107209223(IDH3A)
CCW: 104697486(IDH3A)
FPG: 101911234(IDH3A) 101917018 101924179(IDH3B)
FCH: 102046523(IDH3B) 102049683(IDH3G) 102059274(IDH3A)
CLV: 102084068(IDH3A) 102089326(IDH3B)
EGZ: 104130745(IDH3A) 104134110
AAM: 106485317(IDH3B) 106496514(IDH3A)
ASN: 102376426(IDH3B) 102384371(IDH3G) 102387605(IDH3A)
AMJ: 102572722(IDH3G) 102572950(IDH3A) 106737711(IDH3B)
PSS: 102447300(IDH3B) 102452545(IDH3A)
CMY: 102940870 102946721(IDH3A)
CPIC: 101937934(IDH3B) 101944131(IDH3G) 101949218(IDH3A)
ACS: 100558969(idh3b) 100566326(idh3a) 100567899(idh3g)
PVT: 110074541(IDH3A) 110078605(IDH3G) 110079816(IDH3B)
PBI: 103057793(IDH3G) 103058661(IDH3A) 103060348(IDH3B)
GJA: 107105573(IDH3G) 107110629(IDH3A) 107117632(IDH3B)
XLA: 108711283(idh3a.L) 443821(idh3b.S) 444419(idh3a.S) 444551(idh3g.S)
XTR: 100144949(idh3b) 394979(idh3a) 594985(idh3g)
NPR: 108784060(IDH3A) 108801780(IDH3G) 108802712(IDH3B)
DRE: 393926(idh3a) 415247(idh3b) 550579(idh3g)
IPU: 100528472(idh3a) 108275983(IDH3G) 108276129 108279145(idh3b)
AMEX: 103022909(idh3b) 103033368 103040116(idh3a) 103045952
TRU: 101066481(idh3g) 101068530(idh3a) 101078713(idh3b)
LCO: 104917860(idh3a) 104928357 104928936(idh3b) 104932746(idh3g)
NCC: 104946225(idh3g) 104951613 104951620 104953439(idh3a) 104964856(idh3b)
OLA: 101156895 101164134(idh3a) 101166544(idh3b) 101169534(idh3g)
XMA: 102224210(idh3a) 102227101(idh3b) 102236069(idh3g)
PRET: 103460078(idh3a) 103465018(idh3b) 103466577 103467325(idh3g)
NFU: 107381511(idh3a) 107385459(idh3b) 107390856(idh3g)
CSEM: 103378915 103379971(idh3a) 103384582(idh3g) 103385211 103386635(idh3b)
BPEC: 110164549(idh3g) 110166714(idh3b) 110169069(idh3a)
LCM: 102349413(IDH3A) 102351121(IDH3G) 102357101(IDH3B) 102362883
CMK: 103173064(idh3b) 103188099(idh3a)
DSI: Dsimw501_GD11857(Dsim_GD11857) Dsimw501_GD14133(Dsim_GD14133) Dsimw501_GD15579(Dsim_GD15579) Dsimw501_GD18486(Dsim_GD18486) Dsimw501_GD21232(Dsim_GD21232)
CEL: CELE_C30F12.7(idhg-2) CELE_C37E2.1(idhb-1) CELE_F35G12.2(idhg-1) CELE_F43G9.1(idha-1)
ATH: AT1G32480(IDH-IV) AT2G17130(IDH2) AT3G09810(IDH-VI) AT4G35260(IDH1) AT4G35650(IDH-III) AT5G03290(IDH-V)
LJA: Lj0g3v0312989.1(Lj0g3v0312989.1) Lj2g3v1646570.1(Lj2g3v1646570.1) Lj2g3v1646570.2(Lj2g3v1646570.2) Lj5g3v0659740.1(Lj5g3v0659740.1) Lj5g3v0659740.2(Lj5g3v0659740.2)
DOSA: Os01t0276100-01(Os01g0276100) Os02t0595500-01(Os02g0595500) Os04t0479200-01(Os04g0479200)
ATS: 109758292(LOC109758292) 109772564(LOC109772564) 109773327(LOC109773327) 109784280(LOC109784280)
APRO: F751_3437
SCE: YNL037C(IDH1) YOR136W(IDH2)
KMX: KLMA_20575(IDH2) KLMA_80139(IDH1)
NCS: NCAS_0B06290(NCAS0B06290) NCAS_0H02250(NCAS0H02250)
NDI: NDAI_0B03590(NDAI0B03590) NDAI_0C01410(NDAI0C01410)
TPF: TPHA_0D01560(TPHA0D01560) TPHA_0E01480(TPHA0E01480) TPHA_0J02770(TPHA0J02770)
TBL: TBLA_0B02240(TBLA0B02240) TBLA_0B06910(TBLA0B06910)
TDL: TDEL_0A03370(TDEL0A03370) TDEL_0C03840(TDEL0C03840)
KAF: KAFR_0B06370(KAFR0B06370) KAFR_0J01410(KAFR0J01410)
PIC: PICST_42313(IDH2) PICST_91057(IDH1)
CAUR: QG37_07052
SLB: AWJ20_1546(IDH1) AWJ20_2295(IDH2)
NCR: NCU00775(tca-6) NCU07697(tca-4)
NTE: NEUTE1DRAFT116362(NEUTE1DRAFT_116362) NEUTE1DRAFT118602(NEUTE1DRAFT_118602)
ANG: ANI_1_798074(An08g05580) ANI_1_906164(An18g06760)
SPO: SPAC11G7.03(idh1) SPBC902.05c(idh2)
ABP: AGABI1DRAFT113316(AGABI1DRAFT_113316) AGABI1DRAFT113330(AGABI1DRAFT_113330)
ABV: AGABI2DRAFT135516(AGABI2DRAFT_135516) AGABI2DRAFT192040(AGABI2DRAFT_192040)
DDI: DDB_G0271344(idhA) DDB_G0293872(idhB)
DFA: DFA_05642(idhA) DFA_10000(idhB)
EFE: EFER_3668
KPNK: BN49_4521
XFA: XF_2596
XFT: PD_1973(icdA)
XCC: XCC0967(icd)
XCB: XC_3268
XCA: xcc-b100_3384(icd1)
XCP: XCR_1165
XCV: XCV1076
XAX: XACM_1027
XAC: XAC1046(icd)
XCI: XCAW_03534(leuB)
XOO: XOO1024(icd)
XOM: XOO0926(XOO0926)
XOP: PXO_02485
XOR: XOC_1121
XAL: XALC_0579
XPH: XppCFBP6546_06235(XppCFBP6546P_06235)
SML: Smlt0982
SMT: Smal_0828
SMZ: SMD_0856
PSUW: WQ53_02245
PSD: DSC_12115
LEZ: GLE_1654
LEM: LEN_3313(leuB)
DKO: I596_2711
SON: SO_1538
SDN: Sden_2561
SFR: Sfri_2779
SAZ: Sama_2423
SBL: Sbal_1368
SLO: Shew_2760
SSE: Ssed_3318
SPL: Spea_2980
SHL: Shal_3069
SWD: Swoo_3466
SWP: swp_3606
SVO: SVI_1132
SPSW: Sps_02235
ILO: IL0861
CPS: CPS_3540
PHA: PSHAb0465
PAT: Patl_3197
PSM: PSM_B0541
PSEO: OM33_18470
PSPO: PSPO_b0908
PART: PARC_b0717
AMAL: I607_04505
AMAE: I876_04715
AMAO: I634_04890
AMAD: I636_04735
AMAI: I635_04710
AMAG: I533_04470
AMAC: MASE_04350
AAUS: EP12_04695
GNI: GNIT_2478
FBL: Fbal_2814
MVS: MVIS_3870(icd)
MCA: MCA3071
MAH: MEALZ_3026(icd)
AEH: Mlg_0664
GAI: IMCC3135_33170(icd_3)
CSA: Csal_1434
HAM: HALO1246
ABO: ABO_0296(icd)
ADI: B5T_00711(icd)
AXE: P40_03350
AHA: AHA_1152
ASA: ASA_3183
AVR: B565_3077
AMED: B224_4096
ASR: WL1483_4388(idh5)
ACAV: VI35_15655
OCE: GU3_06935
REH: H16_B1016(icd3)
CNC: CNE_2c09750(leuB)
CGD: CR3_3459
BXE: Bxe_C0665
BXB: DR64_7780
HAR: HEAR3270(icd1)
MMS: mma_3499(idh)
CFU: CFU_0031(citC)
LCH: Lcho_4250
TIN: Tint_2512
THI: THI_2911(idh2)
MXA: MXAN_6337
CCX: COCOR_06955(leuB2)
SCL: sce5773(icd1) sce6432(leuB2)
HOH: Hoch_0287
BBA: Bd1264(leuB)
BBAT: Bdt_1246(leuB)
BBW: BDW_04345
BBAC: EP01_16250
BEX: A11Q_1653
VGO: GJW-30_1_02260(icd_1)
MET: M446_0777
GOX: GOX1336
GOH: B932_1561
GDI: GDI1991
GDJ: Gdia_0214
GXY: GLX_27020
GXL: H845_645
KEU: S101446_03035(idh3)
APK: APA386B_2558(icd1)
ASZ: ASN_91(icd1)
THL: TEH_24000(icd)
CAC: CA_C0972(citC)
CAE: SMB_G0989(icd)
CAY: CEA_G0983(citC)
CBO: CBO0419
CBA: CLB_0452
CBH: CLC_0485
CBY: CLM_0498
CBL: CLK_3621
CBB: CLD_0324
CBI: CLJ_B0487
CBN: CbC4_1895
CBF: CLI_0504
CBM: CBF_0471
CPAS: Clopa_3427
CPAT: CLPA_c14680(leuB1)
CPAE: CPAST_c14680(leuB1)
CSQ: CSCA_3671
CLD: CLSPO_c04570(icd)
CACE: CACET_c05310(icd)
CTYK: CTK_C06630(citC)
AMT: Amet_1319
CCEL: CCDG5_1613
HSC: HVS_05270(icd2)
CPY: Cphy_3096
HSD: SD1D_0729
CPRO: CPRO_08860(icd)
CDF: CD630_08340(icd)
PDC: CDIF630_00953(icd)
PDF: CD630DERM_08340(icd)
CST: CLOST_1243(icd)
PTH: PTH_2517(LeuB)
DAU: Daud_1038
ELM: ELI_1525
AWO: Awo_c24380(icd)
TMR: Tmar_1163
BPRS: CK3_23360
CHY: CHY_1107
MTA: Moth_0993
ADG: Adeg_1102
TPZ: Tph_c09030(leuB1)
CSC: Csac_0751
ATE: Athe_0525
APR: Apre_1101
MED: MELS_0492
MHG: MHY_29150
AIN: Acin_1202(icd)
LPIL: LIP_1411
ACTI: UA75_18165
ACAD: UA74_17640
RXY: Rxyl_1297
ELE: Elen_2334
CBAC: JI75_08125
CYA: CYA_1467
CYB: CYB_1678
TEL: tlr0302
AMR: AM1_5753(icd)
GVI: gvip428(icd)
GLJ: GKIL_0806(icd)
DET: DET0450
DEH: cbdbA408
DEV: DhcVS_392
DMC: btf_415(icd)
DMD: dcmb_461(icd)
DMG: GY50_0375
DUC: UCH007_03820(icd)
HAU: Haur_1453
STI: Sthe_1662
TTR: Tter_0788
PSL: Psta_0983
PLM: Plim_0079
PLS: VT03_27220(icd)
PLH: VT85_11360(hicd)
TTF: THTE_1950
GES: VT84_27710(icd_2) VT84_27735(hicd) VT84_27740(icd_3)
IPA: Isop_1279
PBOR: BSF38_05134(hicd)
ACA: ACP_1462
SUS: Acid_7350
ABAC: LuPra_05591(icd_2)
EMI: Emin_0404
EPO: Epro_0346(icd)
LBA: Lebu_1446
GAU: GAU_2477(icd)
GBA: J421_3937
SRU: SRU_1677
SRM: SRM_01881(icd)
HSW: Hsw_4120
CTS: Ctha_2161
PMO: Pmob_1706
DTN: DTL3_1456(l(1)G0156)
CABY: Cabys_3783
NMV: NITMOv2_2967(IDH) NITMOv2_3291(icd)
LFC: LFE_0769
MTP: Mthe_0549
MCJ: MCON_1315(aksF)
MHI: Mhar_1328
MARC: AR505_0531
ABI: Aboo_1463
IAG: Igag_1773
KCR: Kcr_0970
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kim YO, Koh HJ, Kim SH, Jo SH, Huh JW, Jeong KS, Lee IJ, Song BJ, Huh TL
  Title
Identification and functional characterization of a novel, tissue-specific NAD(+)-dependent isocitrate dehydrogenase beta subunit isoform.
  Journal
J Biol Chem 274:36866-75 (1999)
DOI:10.1074/jbc.274.52.36866
  Sequence
[hsa:3420]

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