KEGG ORTHOLOGY: K00318

ORTHOLOGY: K00318

Entry

K00318 KO

Name

E1.5.99.8

Definition

proline dehydrogenase [EC:1.5.99.8]

Pathway

ko00330

Arginine and proline metabolism

Disease

H00190

Hyperprolinemia (HP)

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Amino acid metabolism
   00330 Arginine and proline metabolism
    K00318  E1.5.99.8; proline dehydrogenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.99  With other acceptors
    1.5.99.8  proline dehydrogenase
     K00318  E1.5.99.8; proline dehydrogenase

Other DBs

RN:

R01253 R05051

COG:

COG0506

GO:

0004657

Genes

HSA:	5625(PRODH)
PTR:	743147(PRODH)
PPS:	100987322
GGO:	101125347(PRODH)
PON:	100455556(PRODH)
MCC:	695506
MMU:	19125(Prodh)
RNO:	680409(Prodh)
CFA:	477562(PRODH)
AML:	100470434
FCA:	101100421(PRODH)
BTA:	505094(PRODH)
ECB:	100050480(PRODH)
GGA:	770734(PRODH)
MGP:	100548053
TGU:	100226342
ACS:	100554382
XLA:	734536(prodh)
XTR:	100494891
DRE:	100333321(prodha) 100537991
TRU:	101078914
OLA:	101165161
BFO:	BRAFLDRAFT_91818
SPU:	583929
DME:	Dmel_CG1417(slgA)
DPO:	Dpse_GA12802
DAN:	Dana_GF20923
DER:	Dere_GG19728
DPE:	Dper_GL16014 Dper_GL16015
DSE:	Dsec_GM23084
DSI:	Dsim_GD17536
DWI:	Dwil_GK25083
DYA:	Dyak_GE17926
DGR:	Dgri_GH24816
DMO:	Dmoj_GI21543
DVI:	Dvir_GJ16015
AGA:	AgaP_AGAP003860
AAG:	AaeL_AAEL013431
CQU:	CpipJ_CPIJ009461
AME:	411808
TCA:	659689
API:	100160914
PHU:	Phum_PHUM316700
ISC:	IscW_ISCW000787
CEL:	CELE_B0513.5
CBR:	CBG22398
BMY:	Bm1_01540
TSP:	Tsp_03356
SMM:	Smp_170690
NVE:	NEMVE_v1g115782
HMG:	100203347
TAD:	TRIADDRAFT_1010
AQU:	100633461
ATH:	AT3G30775(ERD5) AT5G38710
ALY:	ARALYDRAFT_484750 ARALYDRAFT_494099
GMX:	100797464 100798942 100799876 547749(PDH)
MTR:	MTR_7g020820
CSV:	101219166
RCU:	RCOM_1570620
POP:	POPTR_266077 POPTR_859200
VVI:	100254983
OSA:	4349318
DOSA:	Os10t0550900-01(Os10g0550900)
BDI:	100838313
SBI:	SORBI_01g029660(SORBIDRAFT_01g029660)
ZMA:	100281186
SMO:	SELMODRAFT_100996
PPP:	PHYPADRAFT_146384
CRE:	CHLREDRAFT_146649
VCN:	VOLCADRAFT_64330(prodhC)
OTA:	Ot04g03090
SCE:	YLR142W(PUT1)
ERC:	Ecym_4224
LTH:	KLTH0G11616g
PPA:	PAS_chr1-3_0269
VPO:	Kpol_1036p85
ZRO:	ZYRO0F13970g
CGR:	CAGL0M04499g
NCS:	NCAS_0C03160(NCAS0C03160)
NDI:	NDAI_0H01650(NDAI0H01650)
TPF:	TPHA_0C00660(TPHA0C00660)
TBL:	TBLA_0H01140(TBLA0H01140)
TDL:	TDEL_0F04720(TDEL0F04720)
KAF:	KAFR_0H02160(KAFR0H02160)
DHA:	DEHA2E17952g
PIC:	PICST_84147(PUT1)
PGU:	PGUG_01270
CAL:	CaO19.11750(PUT1)
CTP:	CTRG_06001
CDU:	CD36_52370
COT:	CORT_0F01320
YLI:	YALI0B09625g
CLU:	CLUG_01649
CNB:	CNBE4850
LBC:	LACBIDRAFT_327455
MPR:	MPER_03168
CCI:	CC1G_13194
PGR:	PGTG_08459
MBR:	MONBRDRAFT_14774
NGR:	NAEGRDRAFT_47435
DDI:	DDB_G0275669
DPP:	DICPUDRAFT_37322
TGO:	TGME49_002340
PTI:	PHATR_1155
TPS:	THAPSDRAFT_32485
PIF:	PITG_01761
PLU:	plu0185(cpmD)
PAO:	Pat9b_3303 Pat9b_5314
PFC:	PflA506_4421
BUR:	Bcep18194_B1500
AXY:	AXYL_02367
PNA:	Pnap_2465
DDN:	DND132_2748
DAS:	Daes_0705
DPI:	BN4_11930
DPS:	DP2492
DAT:	HRM2_12460(putA1)
DTO:	TOL2_C03260(putA)
MXA:	MXAN_7405
MFU:	LILAB_09325
MSD:	MYSTI_08058
CCX:	COCOR_07996(putA)
SUR:	STAUR_0306
HMR:	Hipma_1680
NPP:	PP1Y_AT10072
BSU:	BSU03200(ycgM) BSU32850(fadM)
BSR:	I33_0365 I33_3393
BSL:	A7A1_1878 A7A1_2503
BSH:	BSU6051_03200(ycgM) BSU6051_32850(fadM)
BSY:	I653_01585 I653_15870
BSS:	BSUW23_01635(ycgM) BSUW23_16070(fadM)
BST:	GYO_0525 GYO_3588
BSO:	BSNT_00568(ycgM) BSNT_04872(yusM)
BSN:	BSn5_07330 BSn5_13180
BSQ:	B657_03200(putB) B657_32850(fadM)
BSUB:	BEST7613_0319(ycgM) BEST7613_6427(fadM)
BSX:	C663_0310 C663_3147(fadM)
BLI:	BL01709(ycgM)
BLD:	BLi00373(ycgM)
BAO:	BAMF_0293(ycgM) BAMF_3126(fadM)
BAY:	RBAM_003440(ycgM) RBAM_029940(yusM)
BAQ:	BACAU_0287(ycgM) BACAU_3020(fadM)
BYA:	BANAU_0286(ycgM) BANAU_3185(fadM)
BAMP:	B938_01475 B938_15340
BAML:	BAM5036_0303(putB) BAM5036_2909(putM)
BAZ:	BAMTA208_01470(ycgM) BAMTA208_16625(fadM)
BQL:	LL3_00301(ycgM) LL3_03406(fadM)
BXH:	BAXH7_00304(ycgM) BAXH7_03395(yusM)
BQY:	MUS_0303(ycgM)
BAMI:	KSO_004175 KSO_017940
BAE:	BATR1942_14350 BATR1942_20240
BHA:	BH2740
BAN:	BA_5253
BAR:	GBAA_5253
BAT:	BAS4879
BAH:	BAMEG_5306
BAI:	BAA_5284
BAX:	H9401_5011
BAL:	BACI_c50190(putA)
BCE:	BC5006
BCA:	BCE_5148
BCZ:	BCZK4736(putA)
BCR:	BCAH187_A0346 BCAH187_A5159
BCB:	BCB4264_A5153
BCU:	BCAH820_5121
BCG:	BCG9842_B0091 BCG9842_B5008
BCQ:	BCQ_0325(putA) BCQ_4829(putA)
BCX:	BCA_5157
BNC:	BCN_0277 BCN_4909
BCF:	bcf_16455 bcf_25145
BCER:	BCK_10205
BCY:	Bcer98_3600
BTK:	BT9727_4721(putA)
BTL:	BALH_2996(putA) BALH_4549(putA)
BTB:	BMB171_C4616
BTT:	HD73_5377
BTC:	CT43_CH0074 CT43_CH5070
BTF:	YBT020_01465 YBT020_24885
BTM:	MC28_4277
BTG:	BTB_c03150(fadM1) BTB_c52350(fadM2)
BTI:	BTG_23555
BTN:	BTF1_23575
BTHT:	H175_ch0074 H175_ch5151
BWE:	BcerKBAB4_4838
BCL:	ABC0247 ABC0963
BPU:	BPUM_0300(ycgM)
BPF:	BpOF4_02605(putA)
BMQ:	BMQ_3822(putB) BMQ_5009(fadM) BMQ_5084
BMD:	BMD_3814(putB) BMD_4994(fadM) BMD_5071
BMH:	BMWSH_0194 BMWSH_0265(putA) BMWSH_1400(yusM)
BSE:	Bsel_0522
BCK:	BCO26_2003
BAG:	Bcoa_2483
BJS:	MY9_0329 MY9_3324
OIH:	OB1350
GKA:	GK3010
GTN:	GTNG_2962
GTH:	Geoth_0558 Geoth_3968
GTE:	GTCCBUS3UF5_33700
GWC:	GWCH70_2939
GYC:	GYMC61_3090
GYA:	GYMC52_3115
GCT:	GC56T3_0493
GMC:	GY4MC1_0490
GGH:	GHH_c30850(fadM)
AFL:	Aflv_1671 Aflv_2486
SAU:	SA1585
SAV:	SAV1766
SAW:	SAHV_1752
SAH:	SaurJH1_1854
SAJ:	SaurJH9_1819
SAM:	MW1707
SAS:	SAS1690
SAR:	SAR1849
SAC:	SACOL1816(putA)
SAX:	USA300HOU_1756(putA)
SAA:	SAUSA300_1711(putA)
SAO:	SAOUHSC_01884
SAE:	NWMN_1658(putA)
SAD:	SAAV_1776(putA)
SUU:	M013TW_1780
SUV:	SAVC_08040
SUH:	SAMSHR1132_16140
SUE:	SAOV_1750
SUJ:	SAA6159_01687(putA)
SUK:	SAA6008_01739(putA)
SUC:	ECTR2_1604
SUT:	SAT0131_01880
SUQ:	HMPREF0772_11387(putA)
SUZ:	MS7_1770(fadM)
SUD:	ST398NM01_1818
SUX:	SAEMRSA15_16730
SUW:	SATW20_17570
SUG:	SAPIG1818
SUF:	SARLGA251_16540
SAB:	SAB1624
SUY:	SA2981_1722
SAUB:	C248_1812
SAUM:	BN843_17690
SEP:	SE1437
SER:	SERP1324(putA)
SHA:	SH1157
SSP:	SSP0999
SCA:	Sca_1371
SLG:	SLGD_01166
SLN:	SLUG_11640
SSD:	SPSINT_1533
SDT:	SPSE_1026(putA)
SWA:	A284_04955
LSP:	Bsph_0181 Bsph_1130 Bsph_4737
HHD:	HBHAL_3946(prodh1) HBHAL_4120(prodh2)
ESI:	Exig_0445 Exig_2356
EAT:	EAT1b_0822
EAN:	Eab7_0421(fadM) Eab7_2200
MCL:	MCCL_1451
BBE:	BBR47_09250(yusM) BBR47_50320
PJD:	Pjdr2_4091 Pjdr2_5339
GYM:	GYMC10_0428 GYMC10_1334
PMS:	KNP414_07774(fadM)
PMQ:	PM3016_7293
PMW:	B2K_36810
AAC:	Aaci_2524
AAD:	TC41_2821
BTS:	Btus_0836
SIV:	SSIL_0452 SSIL_0521
STH:	STH645
TMR:	Tmar_0589
SAY:	TPY_0353
SAP:	Sulac_0318
TNR:	Thena_0704
MTU:	Rv1188
MTV:	RVBD_1188
MTC:	MT1225
MRA:	MRA_1198
MTF:	TBFG_11212
MTB:	TBMG_02794
MTK:	TBSG_02808
MTZ:	TBXG_002774
MTG:	MRGA327_07485
MTI:	MRGA423_07430
MTE:	CCDC5079_1099
MTL:	CCDC5180_1092
MTO:	MTCTRI2_1219
MTD:	UDA_1188
MTN:	ERDMAN_1330
MTJ:	J112_06415
MTUB:	MT7199_1217
MBO:	Mb1220
MBB:	BCG_1250
MBT:	JTY_1223
MBM:	BCGMEX_1222
MBK:	K60_012800
MAF:	MAF_12070
MCE:	MCAN_11991
MCQ:	BN44_11328
MCV:	BN43_30256
MCX:	BN42_21054
MCZ:	BN45_30250
MPA:	MAP2592c
MAV:	MAV_1332
MIT:	OCO_12400
MIR:	OCQ_12420
MIA:	OCU_12360
MID:	MIP_01980
MSM:	MSMEG_5117
MSG:	MSMEI_4989
MSA:	Mycsm_04901
MUL:	MUL_0933(putA)
MVA:	Mvan_4525
MAB:	MAB_1331
MMV:	MYCMA_0702(fadM)
MMC:	Mmcs_4025
MKM:	Mkms_4100
MJL:	Mjls_4255
MMI:	MMAR_4252(putA)
MRH:	MycrhN_3663
MMM:	W7S_06055
MCB:	Mycch_3929
MLI:	MULP_04431(putA)
ASD:	AS9A_4539
NFA:	nfa23550
NCY:	NOCYR_4495(putA)
NBR:	O3I_016505 O3I_035895
RHA:	RHA1_ro00349 RHA1_ro05952
RER:	RER_00940 RER_47050
ROP:	ROP_29510 ROP_60140
REQ:	REQ_14230
GBR:	Gbro_1295
GPO:	GPOL_c38820
GOR:	KTR9_1218 KTR9_4157
SRT:	Srot_2793
SCO:	SCO5519(SC8D9.31)
SMA:	SAV_2724(putA)
SGR:	SGR_1989
SCB:	SCAB_27001
SSX:	SACTE_4717
SVL:	Strvi_1881
SCT:	SCAT_4352
SCY:	SCATT_43390
SFA:	Sfla_1821
SBH:	SBI_00188 SBI_03535
SHY:	SHJG_6616
SHO:	SHJGH_6376
SVE:	SVEN_5196
SDV:	BN159_2884
SALB:	XNR_1312
STRP:	F750_5013
KSK:	KSE_55750
CMC:	CMN_02349
KSE:	Ksed_24480
ICA:	Intca_0641 Intca_1155
PAC:	PPA0316
PAK:	HMPREF0675_3358
PAV:	TIA2EST22_01595
PAX:	TIA2EST36_01580
PAZ:	TIA2EST2_01515
PAW:	PAZ_c03350(fadM)
PAD:	TIIST44_06275
PCN:	TIB1ST10_01625
PACC:	PAC1_01635
PACH:	PAGK_0338
PPC:	HMPREF9154_0437
PBO:	PACID_28060
PRA:	PALO_08985
MPH:	MLP_48200 MLP_50720
NCA:	Noca_0088 Noca_0480
KFL:	Kfla_6401
TFU:	Tfu_0434
NDA:	Ndas_0078
NAL:	B005_2868
TCU:	Tcur_4460
SRO:	Sros_3097 Sros_3332
FRA:	Francci3_2823
FRE:	Franean1_2428
FRI:	FraEuI1c_4694
FAL:	FRAAL4348
FSY:	FsymDg_4062
ACE:	Acel_0248
NML:	Namu_0201
GOB:	Gobs_1424
BSD:	BLASA_1200
MMAR:	MODMU_1431
KRA:	Krad_4483
SEN:	SACE_1978
SVI:	Svir_02730
TBI:	Tbis_1511
AMD:	AMED_2662(putA)
AMM:	AMES_2634(putA)
PDX:	Psed_5634
AMI:	Amir_1081
SESP:	BN6_12840 BN6_81020
STP:	Strop_0342
SAQ:	Sare_0409
MAU:	Micau_5664
MIL:	ML5_2832 ML5_4369
VMA:	VAB18032_01850 VAB18032_03300
AMS:	AMIS_75930
ASE:	ACPL_7874
CAI:	Caci_0646 Caci_8354
SNA:	Snas_5760
RXY:	Rxyl_2923
CWO:	Cwoe_0662
ABA:	Acid345_1338
ACA:	ACP_1336
ACM:	AciX9_2586
GMA:	AciX8_4228
TSA:	AciPR4_3359
TRS:	Terro_0937
SUS:	Acid_2007
PDI:	BDI_2251
TFO:	BFO_2738
SRU:	SRU_0546
SRM:	SRM_00632
RMR:	Rmar_0183
RMG:	Rhom172_0165
CPI:	Cpin_6455
NKO:	Niako_4653
PHE:	Phep_1516
SHG:	Sph21_2274
SCN:	Solca_2597
HHY:	Halhy_6381
SGN:	SGRA_1937
CMR:	Cycma_2631
BBD:	Belba_2274
EVI:	Echvi_0119
CHU:	CHU_0720(pdh)
DFE:	Dfer_4393
SLI:	Slin_5730
LBY:	Lbys_0766
RSI:	Runsl_1931
FLI:	Fleli_0710
EOL:	Emtol_3293
FAE:	FAES_2534
MTT:	Ftrac_1256
GFO:	GFO_1493
FJO:	Fjoh_2814
FPS:	FP1706
FBR:	FBFL15_1784(putA)
FCO:	FCOL_00365
FIN:	KQS_06785(putA)
COC:	Coch_2181
CCM:	Ccan_08680
RBI:	RB2501_15259
ZPR:	ZPR_1743 ZPR_2712
CAT:	CA2559_10548
RAN:	Riean_1779
RAI:	RA0C_2077
RAR:	RIA_0393
RAG:	B739_0068
RAE:	G148_1804
FBC:	FB2170_10826
CAO:	Celal_4182
CLY:	Celly_2975
WVI:	Weevi_0393
KDI:	Krodi_2238
LAN:	Lacal_2410
ZGA:	zobellia_4535
MRS:	Murru_2732 Murru_3084
ASL:	Aeqsu_2642
ORH:	Ornrh_2210
PTQ:	P700755_000452
NDO:	DDD_2869
POM:	MED152_02740
FBA:	FIC_00798
FTE:	Fluta_2927
OHO:	Oweho_1826
GAU:	GAU_2853
CTS:	Ctha_1603
IAL:	IALB_1445
TRO:	trd_A0598
STI:	Sthe_2631 Sthe_3502
ATM:	ANT_04210
CAP:	CLDAP_09300
DRA:	DR_0814
DGE:	Dgeo_0851
DDR:	Deide_13840
DMR:	Deima_1365
DPT:	Deipr_1833
DGO:	DGo_CA2363(putA)
DPD:	Deipe_2785
TRA:	Trad_1880
TTH:	TTC1214
TTJ:	TTHA1579
TTS:	Ththe16_1597
TTL:	TtJL18_0466
TSC:	TSC_c22670
THC:	TCCBUS3UF1_4400
TOS:	Theos_1563
MRB:	Mrub_2640
MRE:	K649_09335
MSV:	Mesil_3124
OPR:	Ocepr_2043
MHD:	Marky_2141
LFC:	LFE_1683
LFI:	LFML04_0949(putA)
DDF:	DEFDS_1068
DAP:	Dacet_1508
CNI:	Calni_0884
FSI:	Flexsi_1433
TTR:	Tter_0599
MHI:	Mhar_0049
HSL:	OE3955F(putA)
HMA:	rrnAC2471(yusM)
HHI:	HAH_2902(yusM)
HLA:	Hlac_0351
HMU:	Hmuk_1107
HTU:	Htur_0496 Htur_2929
NMG:	Nmag_0949 Nmag_4054
HVO:	HVO_0331
HME:	HFX_0316(yusM)
HJE:	HacjB3_01060
HBO:	Hbor_20520 Hbor_28400
HXA:	Halxa_0553 Halxa_2277
NAT:	NJ7G_1955
NPE:	Natpe_0763 Natpe_3583
NGE:	Natgr_2462
HRU:	Halru_2250
NOU:	Natoc_2625
NIR:	NSED_08125
NGA:	Ngar_c32560
HAH:	Halar_0998

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Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   COG (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
   KEGG RCLASS (2)   
Gene (2491)   
   KEGG GENES (604)   
   KEGG DGENES (22)   
   KEGG EGENES (336)   
   KEGG MGENES (1529)   
Protein sequence (514)   
   UniProt (514)   
All databases (3022)   

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