KEGG ORTHOLOGY: K00665

ORTHOLOGY: K00665

Entry

K00665 KO

Name

FASN

Definition

fatty acid synthase, animal type [EC:2.3.1.85]

Pathway

ko00061	Fatty acid biosynthesis
ko04910	Insulin signaling pathway

Module

M00082	Fatty acid biosynthesis, initiation
M00083	Fatty acid biosynthesis, elongation

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Lipid metabolism
   00061 Fatty acid biosynthesis
    K00665  FASN; fatty acid synthase, animal type
Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K00665  FASN; fatty acid synthase, animal type
KEGG pathway modules [BR:ko00002]
Pathway module
  Carbohydrate and lipid metabolism
   Fatty acid metabolism
    M00082  Fatty acid biosynthesis, initiation
     K00665  FASN; fatty acid synthase, animal type
    M00083  Fatty acid biosynthesis, elongation
     K00665  FASN; fatty acid synthase, animal type
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.85  fatty-acid synthase
     K00665  FASN; fatty acid synthase, animal type
Lipid biosynthesis proteins [BR:ko01004]
Fatty acid synthase
  Animal type
   K00665  FASN; fatty acid synthase, animal type

Other DBs

RN:

R01624 R01626 R01706 R04355 R04428 R04430 R04533 R04534 R04535 R04536 R04537 R04543 R04544 R04566 R04568 R04725 R04726 R04952 R04953 R04954 R04956 R04957 R04959 R04960 R04962 R04963 R04965 R04967 R04968 R04970 R08159

GO:

0004312

Genes

HSA:	2194(FASN)
PTR:	454986(FASN)
PPS:	100985873(FASN)
GGO:	101151060(FASN)
PON:	100456558(FASN)
MCC:	715708(FASN)
MMU:	14104(Fasn)
RNO:	50671(Fasn)
CFA:	483378(FASN)
AML:	100468470
FCA:	100270775(FASN)
BTA:	281152(FASN)
SSC:	397561(FASN)
ECB:	100057311(FASN)
MDO:	100025176(FASN)
SHR:	100924144(FASN)
GGA:	396061(FASN)
MGP:	100542651
TGU:	100226957(FASN)
ACS:	100563002
XTR:	100487052
DRE:	335859(fasn) 559001
TRU:	101069108
OLA:	101171365
CIN:	100181277
SPU:	764917
DME:	Dmel_CG17374 Dmel_CG3523 Dmel_CG3524(v(2)k05816)
DPO:	Dpse_GA17497 Dpse_GA17498 Dpse_GA26263
DAN:	Dana_GF14400 Dana_GF14401
DER:	Dere_GG23076 Dere_GG24919 Dere_GG24920
DPE:	Dper_GL12292 Dper_GL18554
DSE:	Dsec_GM18393
DSI:	Dsim_GD23205 Dsim_GD23207
DWI:	Dwil_GK12914 Dwil_GK18430 Dwil_GK18431
DYA:	Dyak_GE18209 Dyak_GE18210
DGR:	Dgri_GH10962 Dgri_GH10963 Dgri_GH20680
DMO:	Dmoj_GI10509 Dmoj_GI10520 Dmoj_GI23207
DVI:	Dvir_GJ21725 Dvir_GJ21736 Dvir_GJ22868
AGA:	AgaP_AGAP001899 AgaP_AGAP008468 AgaP_AGAP009176
AAG:	AaeL_AAEL001194 AaeL_AAEL002204 AaeL_AAEL002228 AaeL_AAEL002237 AaeL_AAEL008160
CQU:	CpipJ_CPIJ003494 CpipJ_CPIJ003495 CpipJ_CPIJ005595 CpipJ_CPIJ008367
AME:	411959 412815
NVI:	100121447(NV10111)
TCA:	658024 658944 658978 659016 659179 660113 660178 662899
API:	100162692 100166426 100167255
PHU:	Phum_PHUM080440 Phum_PHUM448390 Phum_PHUM565830
ISC:	IscW_ISCW009053
CEL:	CELE_F32H2.5(fasn-1)
CBR:	CBG12408(Cbr-fasn-1)
BMY:	Bm1_35180
TSP:	Tsp_06638
TAD:	TRIADDRAFT_31339 TRIADDRAFT_34034 TRIADDRAFT_34041

» show all

Reference

PMID:2717611

Authors

Amy CM, Witkowski A, Naggert J, Williams B, Randhawa Z, Smith S

Title

Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase.

Journal

Proc Natl Acad Sci U S A 86:3114-8 (1989)

All links

Ontology (5)   
   KEGG BRITE (4)   
   GO (1)   
Pathway (1925)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1919)   
Chemical reaction (46)   
   KEGG ENZYME (1)   
   KEGG REACTION (31)   
   KEGG RCLASS (14)   
Gene (363)   
   KEGG GENES (94)   
   KEGG DGENES (10)   
   KEGG EGENES (37)   
   KEGG MGENES (222)   
Protein sequence (66)   
   UniProt (66)   
Literature (1)   
   PubMed (1)   
All databases (2406)   

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