KEGG   ORTHOLOGY: K00699Help
Entry
K00699                      KO                                     

Name
UGT
Definition
glucuronosyltransferase [EC:2.4.1.17]
Pathway
Pentose and glucuronate interconversions
Ascorbate and aldarate metabolism
Steroid hormone biosynthesis
Starch and sucrose metabolism
Retinol metabolism
Porphyrin and chlorophyll metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Chemical carcinogenesis
Module
M00014  
Glucuronate pathway (uronate pathway)
M00129  
Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Disease
H00208  
Hyperbilirubinemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    K00699  UGT; glucuronosyltransferase
   00053 Ascorbate and aldarate metabolism
    K00699  UGT; glucuronosyltransferase
   00500 Starch and sucrose metabolism
    K00699  UGT; glucuronosyltransferase
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K00699  UGT; glucuronosyltransferase
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K00699  UGT; glucuronosyltransferase
   00860 Porphyrin and chlorophyll metabolism
    K00699  UGT; glucuronosyltransferase
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K00699  UGT; glucuronosyltransferase
   00982 Drug metabolism - cytochrome P450
    K00699  UGT; glucuronosyltransferase
   00983 Drug metabolism - other enzymes
    K00699  UGT; glucuronosyltransferase
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K00699  UGT; glucuronosyltransferase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Other carbohydrate metabolism
    M00014  Glucuronate pathway (uronate pathway)
     K00699  UGT; glucuronosyltransferase
  Nucleotide and amino acid metabolism
   Cofactor and vitamin biosynthesis
    M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
     K00699  UGT; glucuronosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     K00699  UGT; glucuronosyltransferase
Glycosyltransferases [BR:ko01003]
 Others
  Hydrophobic molecule
   K00699  UGT; glucuronosyltransferase
BRITE hierarchy
Other DBs
Genes
HSA: 
10720(UGT2B11) 10941(UGT2A1) 54490(UGT2B28) 54575(UGT1A10) 54576(UGT1A8) 54577(UGT1A7) 54578(UGT1A6) 54579(UGT1A5) 54600(UGT1A9) 54657(UGT1A4) 54658(UGT1A1) 54659(UGT1A3) 574537(UGT2A2) 7363(UGT2B4) 7364(UGT2B7) 7365(UGT2B10) 7366(UGT2B15) 7367(UGT2B17) 79799(UGT2A3)
PTR: 
100611992(UGT2B11) 461285(UGT2B4) 461287(UGT2B10) 461289(UGT2B15) 471217(UGT2B28) 471218(UGT2B7) 471219(UGT2B28) 471220(UGT2A3) 739942(UGT1A6) 742890(UGT2A1) 743607(UGT2B17)
PPS: 
GGO: 
PON: 
100171521(UGT2B7) 100172533(UGT1A3) 100172560(UGT1A6) 100173720(UGT1A9) 100174202(UGT2A3) 100441531(UGT2B10) 100444573 100445423 100446928(UGT2B4) 100447782(UGT2A1) 100460599(UGT2B17)
MCC: 
100427327 574147(UGT2B33) 574210(UGT1A1) 613249(UGT2B9*2) 709132(UGT2B4) 709234(UGT2B4) 709420(UGT2A3) 710412(UGT2B15)
MCF: 
102118731 102121904(UGT2A1) 102122035(UGT1A9) 102123935 102124844(UGT2A3) 102125239(UGT2B23) 102126139(mfUGT2B33) 102127013 102127692 102127901(UGT2B9) 102128580(UGT2B20)
MMU: 
100559(Ugt2b38) 100727(Ugt2b34) 112417(Ugt2b37) 22236(Ugt1a2) 22238(Ugt2b5) 231396(Ugt2b36) 243085(Ugt2b35) 394430(Ugt1a10) 394432(Ugt1a7c) 394433(Ugt1a5) 394434(Ugt1a9) 394435(Ugt1a6b) 394436(Ugt1a1) 552899(Ugt2a2) 71773(Ugt2b1) 72094(Ugt2a3) 94215(Ugt2a1) 94284(Ugt1a6a)
RNO: 
113992(Ugt1a6) 154516(Ugt1a7c) 24861(Ugt1a1) 24862(Ugt2b) 266685(Ugt2b17) 286954(Ugt2b1) 286989(Ugt2b7) 289533(Ugt2a3) 29623(Ugt2b37) 301595(Ugt1a8) 305264(Ugt2b10) 396527(Ugt1a2) 396551(Ugt1a3) 396552(Ugt1a9) 501907(RGD1559459) 574523(Ugt1a5) 63867(Ugt2a1) 83808(Ugt2b15)
CGE: 
HGL: 
TUP: 
CFA: 
100686607 100856068 100856129 403629(UGT1A6) 442984(UGT2B31) 475163(UGT2A1) 480777(UGT2B4) 482178 608760(UGT2B4)
AML: 
FCA: 
101087059(UGT2A2) 101087662 101098790 493955(UGT1A1) 494146(UGT1A)
PTG: 
BTA: 
100138004(UGT2B11) 100138908 100140261 100296421 286792(UGT1A6) 511743(UGT2A3) 515638(MGC152010) 530553 533587(UGT2B10) 540615(UGT2B17) 615303(UGT2B4) 751790(UGT1A1) 781478
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
CFR: 
BACU: 
103008324(UGT2B4) 103008900 103009971(UGT2A3) 103011957(UGT1A3)
LVE: 
103078119(UGT1A1) 103078627 103081112(UGT2B4)
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
100010818(UGT2A1)
SHR: 
OAA: 
GGA: 
100857136 422660(UGT2A3) 424028(UGT1A1)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
101923845(UGT1A1) 101924619(UGT2A1)
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XTR: 
100135191(ugt1a6) 100489505 447975(ugt2a1)
DRE: 
100002369 100006320(ugt2a1) 100148803 406731(ugt1ab) 553952(ugt2a2) 570913(ugt5g1) 571561 641488(ugt1a1) 792506
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
408788(GB16747) 411021(GB12751)
NVI: 
TCA: 
BMOR: 
100174975(Ugt2) 100500754(UGT10286) 100500757(UGT10289B) 100500758(UGT10100) 100500763(UGT10288) 100862802(UGT33D2) 100862804(UGT33D6) 100862805(UGT33K1) 100862806(UGT33N1) 100862807(UGT33Q1) 100862808(UGT33R1) 100862809(UGT340C1) 100862810(UGT340C2) 100862817(UGT42A1) 100862818(UGT42A2) 100862819(UGT43B1) 100862820(UGT44A1) 100862821(UGT46A2) 100862822(UGT46C2) 100862823(UGT47A1) 100862830(UGT39B1) 100862832(UGT46A1) 100862841(UGT33D7) 100862842(UGT33R2) 101739741(UGT42B1) 101741076 692593(UGT40A1)
API: 
PHU: 
CEL: 
CELE_B0310.5(ugt-46) CELE_C17G1.3(ugt-23) CELE_C18C4.3(ugt-48) CELE_F35H8.6(ugt-58) CELE_F39G3.1(ugt-61) CELE_M88.1(ugt-62) CELE_T04H1.7(ugt-55) CELE_T04H1.8(ugt-56) CELE_T07C5.1(ugt-50)
CBR: 
CBG00090(Cbr-ugt-50) CBG00954(Cbr-ugt-58) CBG09373(Cbr-ugt-48) CBG17190(Cbr-ugt-46) CBG18047(Cbr-ugt-62) CBG23424(Cbr-ugt-56)
BMY: 
LOA: 
TSP: 
NVE: 
TAD: 
SLY: 
CSL: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3931633
  Authors
Green MD, Falany CN, Kirkpatrick RB, Tephly TR
  Title
Strain differences in purified rat hepatic 3 alpha-hydroxysteroid UDP-glucuronosyltransferase.
  Journal
Biochem J 230:403-9 (1985)

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