KEGG ORTHOLOGY: K00830

ORTHOLOGY: K00830

Entry

K00830 KO

Name

AGXT

Definition

alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]

Pathway

ko00250	Alanine, aspartate and glutamate metabolism
ko00260	Glycine, serine and threonine metabolism
ko00630	Glyoxylate and dicarboxylate metabolism
ko00680	Methane metabolism
ko04146	Peroxisome

Module

M00346	Formaldehyde assimilation, serine pathway
M00532	Photorespiration

Disease

H00117

Primary hyperoxaluria (HP)

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
  Energy metabolism
   00680 Methane metabolism
    K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
   00260 Glycine, serine and threonine metabolism
    K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
Cellular Processes
  Transport and catabolism
   04146 Peroxisome
    K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
KEGG pathway modules [BR:ko00002]
Pathway module
  Energy metabolism
   Methane metabolism
    M00346  Formaldehyde assimilation, serine pathway
     K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
  Carbohydrate and lipid metabolism
   Other carbohydrate metabolism
    M00532  Photorespiration
     K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
Enzymes [BR:ko01000]
2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.44  alanine---glyoxylate transaminase
     K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
    2.6.1.45  serine---glyoxylate transaminase
     K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
    2.6.1.51  serine---pyruvate transaminase
     K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
Amino acid related enzymes [BR:ko01007]
Aminotransferase (transaminase)
  Class V
   K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase

Other DBs

RN:

R00369 R00372 R00585 R00588

GO:

0008453 0050281 0004760

Genes

HSA:	189(AGXT)
PTR:	460073(AGXT)
PPS:	100993087(AGXT)
GGO:	101152477(AGXT)
PON:	100171897(AGXT)
MCC:	699941(AGXT)
MMU:	11611(Agxt)
RNO:	24792(Agxt)
CFA:	100855679 607355(AGXT)
AML:	100477831
FCA:	727692(AGXT)
BTA:	789572(AGXT)
SSC:	100517616
ECB:	100067459
MDO:	100616909
SHR:	100921337
OAA:	100080454
GGA:	770344(AGXT)
MGP:	100543344
TGU:	100232024
ACS:	100559450
XLA:	398137(agxt)
XTR:	448338(agxt)
DRE:	436603(agxta) 79378(agxtb)
TRU:	101064586
OLA:	101157325 101174079
BFO:	BRAFLDRAFT_67460
SPU:	575497
DME:	Dmel_CG3926(Spat)
DPO:	Dpse_GA17780
DAN:	Dana_GF22261
DER:	Dere_GG19592
DPE:	Dper_GL14301
DSE:	Dsec_GM12493
DSI:	Dsim_GD16801
DWI:	Dwil_GK20138
DYA:	Dyak_GE16753(Dyak_Spat)
DGR:	Dgri_GH12684
DMO:	Dmoj_GI16356
DVI:	Dvir_GJ16726
AGA:	AgaP_AGAP003490 AgaP_AGAP010387
AAG:	AaeL_AAEL003508 AaeL_AAEL010480
CQU:	CpipJ_CPIJ002835 CpipJ_CPIJ012673
AME:	413678
NVI:	100114599(Spat)
TCA:	657046 657288
CEL:	CELE_T14D7.1(T14D7.1)
CBR:	CBG03195
NVE:	NEMVE_v1g112567
TAD:	TRIADDRAFT_26208
AQU:	100631517
ATH:	AT2G13360(AGT)
ALY:	ARALYDRAFT_480305
GMX:	100786630 732565(SGT3)
MTR:	MTR_3g053890
CSV:	101207975 101217893
RCU:	RCOM_0063050
POP:	POPTR_723016 POPTR_815301
VVI:	100261927
OSA:	4345962
DOSA:	Os08t0502700-01(Os08g0502700)
BDI:	100842260
SBI:	SORBI_07g028080(SORBIDRAFT_07g028080)
ZMA:	100281949(pco084394)
SMO:	SELMODRAFT_147375 SELMODRAFT_228964 SELMODRAFT_448066
PPP:	PHYPADRAFT_176699 PHYPADRAFT_199392 PHYPADRAFT_210069
CRE:	CHLREDRAFT_194541(AGT1) CHLREDRAFT_194609(SGA1a)
VCN:	VOLCADRAFT_74092 VOLCADRAFT_75980
CME:	CMS429C
SCE:	YFL030W(AGX1)
KLA:	KLLA0F08954g
LTH:	KLTH0G18524g
PPA:	PAS_chr4_0416
VPO:	Kpol_1035p37
ZRO:	ZYRO0F03124g
CGR:	CAGL0K12518g
NCS:	NCAS_0C03790(NCAS0C03790)
NDI:	NDAI_0G03130(NDAI0G03130)
TPF:	TPHA_0D00400(TPHA0D00400)
TBL:	TBLA_0G03410(TBLA0G03410)
TDL:	TDEL_0C00620(TDEL0C00620)
KAF:	KAFR_0C03500(KAFR0C03500)
DHA:	DEHA2E01694g
PIC:	PICST_44075
PGU:	PGUG_04024
LEL:	LELG_04960
CAL:	CaO19.1079(AGX1) CaO19.8680(AGX1)
CTP:	CTRG_02765
CDU:	CD36_64910
COT:	CORT_0H02390
YLI:	YALI0E16643g
CLU:	CLUG_05523
NCR:	NCU01821
SMP:	SMAC_02504
PAN:	PODANSg6663
TTT:	THITE_2123604
MTM:	MYCTH_2311910
MGR:	MGG_02525
FGR:	FG10893.1
NHE:	NECHADRAFT_68993
VAL:	VDBG_03393
SSL:	SS1G_10169
ANI:	AN1342.2
NFI:	NFIA_016140
AFM:	AFUA_1G09470
AOR:	AOR_1_1620194(AO090012000926)
ANG:	ANI_1_146074(An08g01000)
AFV:	AFLA_021700
ACT:	ACLA_026030
PCS:	Pc16g02790
CIM:	CIMG_07122
CPW:	CPC735_034570
URE:	UREG_05778
ABE:	ARB_08028
PNO:	SNOG_05049
PTE:	PTT_19689
ZTR:	MYCGRDRAFT_106396
TML:	GSTUM_00011761001
CNE:	CNL05470
CNB:	CNBI1360
CGI:	CGB_D1540C
LBC:	LACBIDRAFT_302783
CCI:	CC1G_05719
SCM:	SCHCODRAFT_10951
UMA:	UM02621.1
MGL:	MGL_0855
PGR:	PGTG_08279
DDI:	DDB_G0289923(agxt)
DPP:	DICPUDRAFT_99972
TGO:	TGME49_039530
PIF:	PITG_11474
VCH:	VC0392
VCE:	Vch1786_I2702
VCJ:	VCD_001231
VCO:	VC0395_A2810
VCR:	VC395_0436
VCM:	VCM66_0377
VCI:	O3Y_01805
VCL:	VCLMA_A0350
VVU:	VV1_1425
VVY:	VV2958
VVM:	VVMO6_00355
VPA:	VP2714
VPB:	VPBB_2534
VHA:	VIBHAR_03710
VSP:	VS_0318
VEX:	VEA_002358
VEJ:	VEJY3_13910
VFU:	vfu_A03125
VFI:	VF_0339
VFM:	VFMJ11_0330
VSA:	VSAL_I0445
PPR:	PBPRA3292
VAN:	VAA_01746
PAR:	Psyc_1388(sgaA)
PCR:	Pcryo_0981
SON:	SO_4343(agxT)
SDN:	Sden_0404
SFR:	Sfri_0426
SAZ:	Sama_3277
SBL:	Sbal_4027
SBM:	Shew185_4005
SBN:	Sbal195_4124
SBP:	Sbal223_3930
SBT:	Sbal678_4157
SBS:	Sbal117_4185
SBB:	Sbal175_0381
SLO:	Shew_0294
SPC:	Sputcn32_3610
SHP:	Sput200_3623
SSE:	Ssed_4160
SPL:	Spea_0350
SHE:	Shewmr4_0366
SHM:	Shewmr7_3660
SHN:	Shewana3_0360
SHW:	Sputw3181_3750
SHL:	Shal_3939
SWD:	Swoo_0447
SWP:	swp_0364
SVO:	SVI_3863
CPS:	CPS_2190 CPS_4878
PAT:	Patl_2043
MBS:	MRBBS_0358(sgaA) MRBBS_0374(sgaA)
AMC:	MADE_1010110
AMAC:	MASE_09565
AMB:	AMBAS45_10015
AMG:	AMEC673_09810
AMK:	AMBLS11_09310
AMAA:	amad1_10675
ALT:	ambt_08000
GAG:	Glaag_2225
GPS:	C427_2940
FBL:	Fbal_3643
MCA:	MCA1406(sgaA)
MMT:	Metme_2697
MAH:	MEALZ_3218(sgaA)
CYQ:	Q91_1512
NOC:	Noc_2128
NHL:	Nhal_2764
NWA:	Nwat_0960
ALV:	Alvin_0550
TMB:	Thimo_2218
TGR:	Tgr7_1551
TKM:	TK90_1895
TNI:	TVNIR_2885(pucG_[H])
HCH:	HCH_05345
RMA:	Rmag_0312
VOK:	COSY_0293
REU:	Reut_B5140
REH:	H16_B1170
RME:	Rmet_5630(sgaA)
CTI:	RALTA_B0770 RALTA_B1073
CNC:	CNE_2c11310(sgaA)
BUR:	Bcep18194_B3022
BXE:	Bxe_B3001
BPH:	Bphy_4253 Bphy_5929
BPY:	Bphyt_6959
BUG:	BC1001_4802
BGE:	BC1002_5143
BGF:	BC1003_4693
BYI:	BYI23_D007780
BPX:	BUPH_01368
PNU:	Pnuc_0602
BPER:	BN118_3316
BPA:	BPP4201
BPAR:	BN117_4271
BBR:	BB4671
BBM:	BN115_4352
BBH:	BN112_3752
BPT:	Bpet4350
AXY:	AXYL_03575
PUT:	PT7_1574
POL:	Bpro_0548
DAC:	Daci_3052
DEL:	DelCs14_3665
VAP:	Vapar_2906
VPE:	Varpa_3160
RTA:	Rta_16260
MPT:	Mpe_A3261
HAR:	HEAR2731(sgaA)
MMS:	mma_0436
CFU:	CFU_0046(sgaA)
NEU:	NE0034
NET:	Neut_0200
NIT:	NAL212_0299
NII:	Nit79A3_0673
NMU:	Nmul_A2538
TBD:	Tbd_2509
SLT:	Slit_0824
BPRC:	D521_0472
DVU:	DVU3121
DVL:	Dvul_0262
DVG:	Deval_2883
DDS:	Ddes_0641
DAT:	HRM2_08190
ADE:	Adeh_2994
ACP:	A2cp1_3194
AFW:	Anae109_2957
ANK:	AnaeK_3093
MFU:	LILAB_07380
MSD:	MYSTI_00252
CCX:	COCOR_07788
SUR:	STAUR_0617
HOH:	Hoch_1789
DTI:	Desti_1316
PEL:	SAR11G3_01299
MLO:	mlr1322
MCI:	Mesci_2041
MOP:	Mesop_3794
MAM:	Mesau_00945 Mesau_03585
MES:	Meso_3308
SME:	SMa1495 SMa2139(sgaA)
SMK:	Sinme_6009
SMQ:	SinmeB_6328
SMX:	SM11_pC0836
SMI:	BN406_03708 BN406_04551(Agxt) BN406_06798(sgaA)
SMEG:	C770_GR4pC0561
SMEL:	SM2011_a1495 SM2011_a2139(sgaA)
SMD:	Smed_5312
RHI:	NGR_b19550 NGR_c26220
SFH:	SFHH103_02473(sgaA)
SFD:	USDA257_c17720(sgaA1) USDA257_c20700(pucG) USDA257_c22040(sgaA2)
BJA:	bll6037 bll6039 blr0373
BJU:	BJ6T_03300 BJ6T_36640 BJ6T_36660
BRA:	BRADO5277 BRADO5278 BRADO6985
BBT:	BBta_0544 BBta_5728 BBta_5729
BRS:	S23_04630 S23_22310
RPA:	RPA0789
RPB:	RPB_4629
RPC:	RPC_4689
RPD:	RPD_0780
RPE:	RPE_0897
RPT:	Rpal_0857
RPX:	Rpdx1_0949
NWI:	Nwi_2413
NHA:	Nham_2804
OCA:	OCAR_6690 OCAR_6692
OCG:	OCA5_c13760(sgaA1) OCA5_c13780(sgaA2)
OCO:	OCA4_c13760(sgaA1) OCA4_c13780(sgaA2)
AOL:	S58_05090 S58_24200 S58_24210
SNO:	Snov_2530
MEX:	Mext_1795 Mext_4200
MEA:	Mex_1p1726(sga) Mex_1p4592(sga)
MDI:	METDI2478(sga) METDI5202(sga)
MCH:	Mchl_2131 Mchl_4570
MRD:	Mrad2831_3670 Mrad2831_6210
MET:	M446_3486 M446_4373 M446_6552
MPO:	Mpop_1747 Mpop_4717
MNO:	Mnod_2767 Mnod_4911 Mnod_7112
BID:	Bind_3524
MSL:	Msil_1714 Msil_3400
HDN:	Hden_0290 Hden_3154
HMC:	HYPMC_3870(sga) HYPMC_4396(sga)
MSC:	BN69_1178
SIL:	SPO3029 SPOA0144
SIT:	TM1040_1983 TM1040_2699
RSP:	RSP_0245
RSH:	Rsph17029_1888
RSQ:	Rsph17025_2018
RSK:	RSKD131_1570
RCP:	RCAP_rcc03109
JAN:	Jann_1162 Jann_2602 Jann_3472
RDE:	RD1_1750(sgaA) RD1_2892(sgaA)
RLI:	RLO149_c015440(sgaA) RLO149_c029700
PDE:	Pden_0729 Pden_3921
DSH:	Dshi_0887(sgaA2) Dshi_2090 Dshi_2489 Dshi_3325(sgaA1)
KVU:	EIO_2210
KVL:	KVU_1756
PGA:	PGA1_c23940
PGL:	PGA2_c21960
OAT:	OAN307_c10730(sgaA) OAN307_c34550
OAR:	OA238_c05570(sgaA) OA238_c09560
SSY:	SLG_07590
GBE:	GbCGDNIH1_0048
ACR:	Acry_1369 Acry_3418
AMV:	ACMV_14160(sgaA) ACMV_P1_00050(sgaA)
MAG:	amb4448
APB:	SAR116_1214
PGV:	SL003B_4273
APC:	HIMB59_00013910
BTS:	Btus_1044
STH:	STH3178
SAY:	TPY_0212
SAP:	Sulac_0192
TNR:	Thena_0262
NBR:	O3I_010440
AAU:	AAur_3518
AAI:	AARI_10400
ARR:	ARUE_c36440
KRH:	KRH_19950
NCA:	Noca_3274
NAL:	B005_5124
BSD:	BLASA_2336
MMAR:	MODMU_5164
SEN:	SACE_3639
PDX:	Psed_1785
RXY:	Rxyl_0923
AYM:	YM304_07780
SCD:	Spica_1210
KDI:	Krodi_0490
MIN:	Minf_1332
GAU:	GAU_3795(sgaA)
PSL:	Psta_2949
IPA:	Isop_3726
SACI:	Sinac_2608
PHM:	PSMK_30680
TLI:	Tlie_0500
SYW:	SYNW1075(spt)
SYC:	syc1934_c(spt)
SYF:	Synpcc7942_2160
SYD:	Syncc9605_1207
SYE:	Syncc9902_1263
SYG:	sync_1566
SYR:	SynRCC307_1294
SYX:	SynWH7803_1345
SYP:	SYNPCC7002_A0177
CYT:	cce_2871
CYP:	PCC8801_3795
CYC:	PCC7424_5094
CYH:	Cyan8802_3847
CYJ:	Cyan7822_4974
AMR:	AM1_2262
CGC:	Cyagr_0477
GLP:	Glo7428_2039
CMP:	Cha6605_5618
ANA:	alr1004
NPU:	Npun_F4445
NOS:	Nos7107_4671
NOP:	Nos7524_0255
AVA:	Ava_5058
ANB:	ANA_C10532
ACY:	Anacy_4554
CSG:	Cylst_2419
CALO:	Cal7507_0547
CALT:	Cal6303_1669
RIV:	Riv7116_2211
PMA:	Pro1037
PMM:	PMM0919(spt)
PMT:	PMT0600(spt)
PMN:	PMN2A_0142
PMI:	PMT9312_0881
PMB:	A9601_09411(spt)
PMC:	P9515_10021(spt)
PMF:	P9303_16451(spt)
PMG:	P9301_09401(spt)
PMH:	P9215_09711(spt)
PMJ:	P9211_10251(spt)
PME:	NATL1_07741(spt)
LEP:	Lepto7376_1947
CEP:	Cri9333_4496
PLP:	Ple7327_3143
SCS:	Sta7437_3030
DRA:	DR_1350
DGE:	Dgeo_1114
DDR:	Deide_11530
DMR:	Deima_1844
DGO:	DGo_CA1580
DPD:	Deipe_3713
TRA:	Trad_1349
TTH:	TTC1813
TTJ:	TTHA0173
TTS:	Ththe16_0216
TTL:	TtJL18_0233
TSC:	TSC_c03320
THC:	TCCBUS3UF1_19850
TOS:	Theos_2072
MRB:	Mrub_0738
MRE:	K649_03330
MSV:	Mesil_0977
MHD:	Marky_1509
NDE:	NIDE1160
MHU:	Mhun_2475
HMA:	rrnAC1999(spaT)
HHI:	HAH_2501(spaT)
NPH:	NP2578A(agt_1)
HLA:	Hlac_1765
HTU:	Htur_1862
NMG:	Nmag_0019
HVO:	HVO_2671
HME:	HFX_2689
HJE:	HacjB3_03325
HXA:	Halxa_3380
NAT:	NJ7G_2948
NPE:	Natpe_2267
NGE:	Natgr_3802
HRU:	Halru_1487
NOU:	Natoc_1744
PCL:	Pcal_1612
PAS:	Pars_1870
HAH:	Halar_1625

» show all

Reference

PMID:19892824

Authors

Schluter A, Real-Chicharro A, Gabaldon T, Sanchez-Jimenez F, Pujol A

Title

PeroxisomeDB 2.0: an integrative view of the global peroxisomal metabolome.

Journal

Nucleic Acids Res 38:D800-5 (2010)

Reference

PMID:19887726

Authors

Nagata M, Ichiyama A, Takayama T, Oda T, Mugiya S, Ozono S

Title

Assay of alanine:glyoxylate aminotransferase in human liver by its serine: glyoxylate aminotransferase activity.

Journal

Biomed Res 30:295-301 (2009)

Reference

PMID:11309139

Authors

Liepman AH, Olsen LJ

Title

Peroxisomal alanine : glyoxylate aminotransferase (AGT1) is a photorespiratory enzyme with multiple substrates in Arabidopsis thaliana.

Journal

Plant J 25:487-98 (2001)

Reference

PMID:3933486

Authors

Takada Y, Noguchi T

Title

Characteristics of alanine: glyoxylate aminotransferase from Saccharomyces cerevisiae, a regulatory enzyme in the glyoxylate pathway of glycine and serine biosynthesis from tricarboxylic acid-cycle intermediates.

Journal

Biochem J 231:157-63 (1985)

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Ontology (8)   
   KEGG BRITE (5)   
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Pathway (33)   
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   KEGG MODULE (17)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (10)   
   KEGG ENZYME (3)   
   KEGG REACTION (4)   
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Gene (1820)   
   KEGG GENES (520)   
   KEGG DGENES (18)   
   KEGG EGENES (340)   
   KEGG MGENES (942)   
Protein sequence (452)   
   UniProt (452)   
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