KEGG ORTHOLOGY: K00898

ORTHOLOGY: K00898

Entry

K00898 KO

Name

E2.7.11.2, PDK

Definition

pyruvate dehydrogenase kinase [EC:2.7.11.2]

Brite

Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.2  [pyruvate dehydrogenase (acetyl-transferring)] kinase
     K00898  E2.7.11.2, PDK; pyruvate dehydrogenase kinase
Protein kinases [BR:ko01001]
Serine/threonine protein kinases: Others
  PDHK family
   K00898  E2.7.11.2, PDK; pyruvate dehydrogenase kinase

Other DBs

GO:

0004740

Genes

HSA:	5164(PDK2) 5165(PDK3) 5166(PDK4)
PTR:	468402(PDK2) 472448(PDK4) 740576(PDK3)
PPS:	100970620(PDK4) 100992308(PDK2) 100995647(PDK3)
GGO:	101129032(PDK2) 101143387(PDK3) 101149286(PDK4)
PON:	100174113(PDK2) 100435148(PDK4) 100462571(PDK3)
MCC:	698726(PDK4) 699394(PDK3) 704169
MMU:	18604(Pdk2) 236900(Pdk3) 27273(Pdk4)
RNO:	296849(Pdk3) 81530(Pdk2) 89813(Pdk4)
CFA:	480868(PDK3) 482310(PDK4) 491075(PDK2)
AML:	100464908(PDK4) 100466029 100476739(PDK2)
FCA:	101092256(PDK4) 101095314(PDK3) 101100013(PDK2)
BTA:	507367(PDK4) 510841(PDK3) 524075(PDK2)
SSC:	100153858(PDK3) 100286778(PDK4) 100516037(PDK2)
ECB:	100052078(PDK4) 100060791(PDK3) 100147514
MDO:	100010271(PDK3) 100017644(PDK4) 100022514(PDK2)
SHR:	100924143(PDK2) 100924902 100934205
OAA:	100088087
GGA:	418595(PDK3) 420570(PDK4)
MGP:	100548787
TGU:	100226102(PDK3) 100230570(PDK4)
ACS:	100560978(pdk4) 100562544 100565122
XLA:	379789(pdk4) 398840
XTR:	100135009(pdk3) 448511(pdk4)
DRE:	393971(pdk2) 560068(pdk3a) 561007(pdk4)
TRU:	101066123 101071739 101074391
OLA:	101155612 101171116 101175202
BFO:	BRAFLDRAFT_114859
CIN:	100185085
SPU:	587933
DME:	Dmel_CG8808(Pdk)
DPO:	Dpse_GA24222
DAN:	Dana_GF12464
DER:	Dere_GG24073
DPE:	Dper_GL17352
DSE:	Dsec_GM21122
DSI:	Dsim_GD10655
DWI:	Dwil_GK15747
DYA:	Dyak_GE19277
DGR:	Dgri_GH19919
DMO:	Dmoj_GI19876
DVI:	Dvir_GJ15047
AGA:	AgaP_AGAP010276
AAG:	AaeL_AAEL007375
AME:	410424(Pdk)
NVI:	100122108(NV11461)
TCA:	662090
API:	100166307
PHU:	Phum_PHUM574180
ISC:	IscW_ISCW013649
CEL:	CELE_ZK370.5(pdhk-2)
CBR:	CBG06929(Cbr-pdhk-2)
BMY:	Bm1_30205
SMM:	Smp_068170.1
NVE:	NEMVE_v1g232588
HMG:	100211141
TAD:	TRIADDRAFT_20860 TRIADDRAFT_53587
ALY:	ARALYDRAFT_896779
GMX:	100037469(PDK3) 100785344 100814079
MTR:	MTR_2g045490 MTR_7g024460
CSV:	101204312 101213546 101229066
RCU:	RCOM_1003500
POP:	POPTR_804707
VVI:	100245923 100266622
OSA:	4344039
DOSA:	Os03t0370000-01(Os03g0370000) Os07t0637300-01(Os07g0637300)
BDI:	100822823 100842984
SBI:	SORBI_01g034390(SORBIDRAFT_01g034390) SORBI_02g040610(SORBIDRAFT_02g040610)
ZMA:	100193944 541677(pdlk1) 542603(pdlk2)
SMO:	SELMODRAFT_108744 SELMODRAFT_93519
PPP:	PHYPADRAFT_150534 PHYPADRAFT_221436
CRE:	CHLREDRAFT_142512(PDK3)
VCN:	VOLCADRAFT_66749
CME:	CMR225C
AGO:	AGOS_AER270W
ERC:	Ecym_2505
PPA:	PAS_chr1-1_0202
ZRO:	ZYRO0D08052g
DHA:	DEHA2C13354g
PIC:	PICST_90317
PGU:	PGUG_05616
LEL:	LELG_05335
CAL:	CaO19.7281
CTP:	CTRG_05965
CDU:	CD36_34370
COT:	CORT_0D01220
YLI:	YALI0C21582g
CLU:	CLUG_01102
NCR:	NCU06760
SMP:	SMAC_06751
PAN:	PODANSg6632
TTT:	THITE_2124496
MTM:	MYCTH_84590
MGR:	MGG_07161
FGR:	FG04416.1
NHE:	NECHADRAFT_95779
VAL:	VDBG_05287
SSL:	SS1G_10371
BFU:	BC1G_15996
ANI:	AN6207.2
NFI:	NFIA_087120
AFM:	AFUA_2G11900
AOR:	AOR_1_836014(AO090026000452)
ANG:	ANI_1_544024(An02g04000)
AFV:	AFLA_134790
ACT:	ACLA_070830
PCS:	Pc20g14220
CIM:	CIMG_05416
CPW:	CPC735_065780
PBL:	PAAG_00094
URE:	UREG_06303
ABE:	ARB_00632
TVE:	TRV_05098
AJE:	HCAG_03915
PNO:	SNOG_15668
PTE:	PTT_00963
ZTR:	MYCGRDRAFT_53419
TML:	GSTUM_00002314001
SPO:	SPAC644.11c(pkp1)
CNE:	CNA00360
CNB:	CNBA0360 CNBH4200
CGI:	CGB_B0390C CGB_H5750W
LBC:	LACBIDRAFT_190061
MPR:	MPER_11803
CCI:	CC1G_15212
SCM:	SCHCODRAFT_70039
MGL:	MGL_2833
PGR:	PGTG_17358
MBR:	MONBRDRAFT_31036
NGR:	NAEGRDRAFT_74828
TBR:	Tb11.02.2390
TCR:	509875.170
LMA:	LMJF_24_0010
LIF:	LINJ_20_0310 LINJ_24_0010
LDO:	LDBPK_200310 LDBPK_240010
LMI:	LMXM_20_0280 LMXM_24_0010
LBZ:	LBRM_20_4500 LBRM_24_0010
PTI:	PHATRDRAFT_13123 PHATRDRAFT_15081 PHATRDRAFT_46264 PHATRDRAFT_50961
TPS:	THAPSDRAFT_1225 THAPSDRAFT_261233(PDK1_1) THAPSDRAFT_37571
PIF:	PITG_00352

» show all

Reference

PMID:17310282

Authors

Roche TE, Hiromasa Y

Title

Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer.

Journal

Cell Mol Life Sci 64:830-49 (2007)

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (522)   
   KEGG GENES (208)   
   KEGG DGENES (21)   
   KEGG EGENES (214)   
   KEGG MGENES (79)   
Protein sequence (173)   
   UniProt (173)   
Literature (1)   
   PubMed (1)   
All databases (700)   

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