KEGG   ORTHOLOGY: K01313Help
Entry
K01313                      KO                                     

Name
F2
Definition
coagulation factor II (thrombin) [EC:3.4.21.5]
Pathway
ko04080  Neuroactive ligand-receptor interaction
ko04610  Complement and coagulation cascades
ko04810  Regulation of actin cytoskeleton
Disease
H00223  Inherited thrombophilia
H01254  Congenital prothrombin deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K01313  F2; coagulation factor II (thrombin)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K01313  F2; coagulation factor II (thrombin)
 Organismal Systems
  Immune system
   04610 Complement and coagulation cascades
    K01313  F2; coagulation factor II (thrombin)
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.5  thrombin
     K01313  F2; coagulation factor II (thrombin)
Peptidases [BR:ko01002]
 Serine Peptidases
  Family S1: chymotrypsin family
   K01313  F2; coagulation factor II (thrombin)
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   K01313  F2; coagulation factor II (thrombin)
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Coagulation and fibrinolysis
   K01313  F2; coagulation factor II (thrombin)
BRITE hierarchy
Genes
HSA: 2147(F2)
PTR: 451158(F2)
PPS: 100975534(F2)
GGO: 101149905(F2)
PON: 100173859(F2)
NLE: 100595467(F2)
MCC: 712729(F2)
MCF: 102131020(F2)
CSAB: 103236354
RRO: 104668398(F2)
RBB: 108521952(F2)
CJC: 100386446(F2)
SBQ: 101049318(F2)
MMU: 14061(F2)
RNO: 29251(F2)
CGE: 100754947(F2)
NGI: 103742495(F2)
HGL: 101720561(F2)
CCAN: 109681600(F2)
OCU: 100009146(F2)
TUP: 102468231(F2)
CFA: 100856539(F2)
AML: 100472871(F2)
UMR: 103672390(F2)
ORO: 101381460(F2)
FCA: 101090463(F2)
PTG: 102950768(F2)
AJU: 106978029(F2)
BTA: 280685(F2)
BOM: 102271164(F2)
BIU: 109569554(F2)
PHD: 102321823(F2)
CHX: 102185018(F2)
OAS: 100307041(F2)
SSC: 100144442(F2)
CFR: 102515763(F2)
CDK: 105106867(F2)
BACU: 103013731(F2)
LVE: 103082406(F2)
OOR: 101289120(F2)
ECB: 100057521(F2)
EPZ: 103566907(F2)
EAI: 106844001(F2)
MYB: 102252492(F2)
MYD: 102752205(F2)
HAI: 109390173(F2)
RSS: 109453694(F2)
PALE: 102877724(F2)
LAV: 100666651(F2)
TMU: 101347713
MDO: 100015821(F2)
SHR: 100915186(F2)
OAA: 100081028(F2)
GGA: 395306(F2)
MGP: 100549057(F2)
CJO: 107314808(F2)
APLA: 101792756(F2)
ACYG: 106043598(F2)
TGU: 100220988(F2)
GFR: 102034334(F2)
FAB: 101811384(F2)
PHI: 102114657(F2)
PMAJ: 107205921(F2)
CCW: 104697991(F2)
FPG: 101912106(F2)
FCH: 102047000(F2)
CLV: 102087936(F2)
EGZ: 104134075(F2)
AAM: 106498225(F2)
ASN: 102370968(F2)
AMJ: 102568064(F2)
PSS: 102449827(F2)
CMY: 102937607(F2)
CPIC: 101938037(F2)
ACS: 100566916(f2)
PVT: 110081895(F2)
PBI: 103065535(F2)
GJA: 107106779(F2)
XLA: 443652(f2.L) 446352(f2.S)
XTR: 548514(f2)
NPR: 108791599(F2)
DRE: 325881(f2)
SRX: 107742559
IPU: 108259272(f2)
AMEX: 103039180(f2)
TRU: 446073(f2)
LCO: 104936791(f2)
NCC: 104959957(f2)
OLA: 101170246
XMA: 102217884(f2)
PRET: 103480906(f2)
NFU: 107384579(f2)
CSEM: 103389837(f2)
HCQ: 109510409(f2)
BPEC: 110172075(f2)
ELS: 105017464(f2)
SFM: 108940837(f2)
LCM: 102347036(F2)
CMK: 103186030(f2)
APLC: 110974931
SKO: 100377746
CRG: 105327809
OBI: 106884382
EPA: 110232337
ADF: 107333270
 » show all
TaxonomyKoalaUniProt
Reference
PMID:6326805
  Authors
MacGillivray RT, Davie EW
  Title
Characterization of bovine prothrombin mRNA and its translation product.
  Journal
Biochemistry 23:1626-34 (1984)
DOI:10.1021/bi00303a007
  Sequence
[bta:280685]
Reference
PMID:2856554
  Authors
Glenn KC, Frost GH, Bergmann JS, Carney DH
  Title
Synthetic peptides bind to high-affinity thrombin receptors and modulate thrombin mitogenesis.
  Journal
Pept Res 1:65-73 (1988)

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