KEGG ORTHOLOGY: K01324

ORTHOLOGY: K01324

Entry

K01324                      KO

Symbol

KLKB1

Name

plasma kallikrein [EC:3.4.21.34]

Pathway

map04610

Complement and coagulation cascades

Disease

H01078

Fletcher factor deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K01324  KLKB1; plasma kallikrein
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01324  KLKB1; plasma kallikrein
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.34  plasma kallikrein
     K01324  KLKB1; plasma kallikrein
Peptidases and inhibitors [BR:ko01002]
Serine peptidases
  Family S1: chymotrypsin family
   K01324  KLKB1; plasma kallikrein

Genes

HSA:	3818(KLKB1)

PTR:	471375(KLKB1)

PPS:	100985593(KLKB1)

GGO:	101142617(KLKB1)

PON:	100172926(KLKB1)

NLE:	100594044 115835879

HMH:	116466086(KLKB1)

MCC:	696639(KLKB1)

MCF:	102142369(KLKB1)

MTHB:

126955234

MNI:	105466552(KLKB1)

CSAB:

103236637(KLKB1)

CATY:

105594265(KLKB1)

PANU:

101004320(KLKB1)

TGE:	112624825(KLKB1)

MLEU:

105540242(KLKB1)

RRO:	104673817(KLKB1)

RBB:	108522428(KLKB1)

TFN:	117086226(KLKB1)

PTEH:

111548503(KLKB1)

CANG:

105524322(KLKB1)

CJC:	100409572(KLKB1)

SBQ:	101048983(KLKB1)

CIMI:

108288135(KLKB1)

CSYR:

103271965(KLKB1)

MMUR:

105882474(KLKB1)

LCAT:

123638620(KLKB1)

PCOQ:

105810082(KLKB1)

OGA:	100950732(KLKB1)

MMU:	16621(Klkb1)

MCAL:

110299702(Klkb1)

MPAH:

110336817(Klkb1)

RNO:	25048(Klkb1)

MCOC:

116071383(Klkb1)

ANU:	117721641(Klkb1)

MUN:	110558008(Klkb1)

CGE:	100767873(Klkb1)

MAUA:

101827641(Klkb1)

PROB:

127220497(Klkb1)

PLEU:

114701164(Klkb1)

MORG:

121433832(Klkb1)

MFOT:

126504788

AAMP:

119811369(Klkb1)

NGI:	103750509(Klkb1)

HGL:	101719264(Klkb1)

CPOC:

100715794(Klkb1)

CCAN:

109684302(Klkb1)

DORD:

105991332(Klkb1)

DSP:	122127383(Klkb1)

PLOP:

125339581(Klkb1)

NCAR:

124983746

MMMA:

107142650(Klkb1)

OCU:

100356267

OPI:	101523823(KLKB1)

TUP:	102485674(KLKB1)

GVR:	103581445(KLKB1)

CFA:	475624(KLKB1)

VVP:	112934777(KLKB1)

NPO:	129503582(KLKB1)

AML:	100468355(KLKB1)

UMR:	103680968(KLKB1)

UAH:	113262285(KLKB1)

UAR:	123784492(KLKB1)

ELK:

111144530

LLV:

125093973

MPUF:

101689429(KLKB1)

MNP:	132006307(KLKB1)

MLK:	131820617(KLKB1)

NVS:	122919283(KLKB1)

ORO:	101379313(KLKB1)

EJU:	114206167(KLKB1)

ZCA:	113924887(KLKB1)

MLX:	118010046(KLKB1)

NSU:	110584170(KLKB1)

LWW:	102726728(KLKB1)

FCA:	101094092(KLKB1)

PYU:	121039709(KLKB1)

PCOO:

112869962(KLKB1)

PBG:	122470993(KLKB1)

PVIV:

125163419(KLKB1)

LRUF:

124520854

PTG:	102971874(KLKB1)

PPAD:

109250991(KLKB1)

PUC:

125923456

AJU:

106982221

HHV:	120237791(KLKB1)

BTA:	533547(KLKB1)

BOM:	102270694(KLKB1)

BIU:	109553560(KLKB1)

BBUB:

102396882(KLKB1)

BBIS:

104985562(KLKB1)

CHX:	102184030(KLKB1)

OAS:

101116376

BTAX:

128068326(KLKB1)

ODA:	120865743(KLKB1)

CCAD:

122432375(KLKB1)

MBEZ:

129549324(KLKB1)

SSC:	397144(KLKB1)

CFR:	102512343(KLKB1)

CBAI:

105067666(KLKB1)

CDK:	105102384(KLKB1)

VPC:	102526079(KLKB1)

ECB:	100056650(KLKB1)

EAI:	106840366(KLKB1)

MYB:	102247445(KLKB1)

MYD:	102764838(KLKB1)

MMYO:

118652088(KLKB1)

MLF:	102426918(KLKB1)

PKL:	118730055(KLKB1)

EFUS:

103290370

MNA:	107534033(KLKB1)

DRO:	112306752(KLKB1)

SHON:

118993096(KLKB1)

AJM:	119036873(KLKB1)

PDIC:

114508386(KLKB1)

PHAS:

123807510(KLKB1)

PPAM:

129064872(KLKB1)

HAI:	109395838(KLKB1)

RFQ:	117021760(KLKB1)

PALE:

102883484(KLKB1)

PGIG:

120618463(KLKB1)

PVP:	105294687(KLKB1)

RAY:	107510433(KLKB1)

MJV:	108396405(KLKB1)

TOD:	119230348 119257004(KLKB1)

SARA:

101551391(KLKB1)

SETR:

126006893(KLKB1)

LAV:

100660779

TMU:

101358166

ETF:	101648903(KLKB1)

DNM:	101423717(KLKB1)

MDO:	100013981(KLKB1)

GAS:	123253136(KLKB1)

SHR:	100917450(KLKB1)

AFZ:

127541438

PCW:	110204309 110204628

OAA:

100086786

GGA:	422723(F11)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

AFUL:

TGU:

LSR:

SCAN:

PMOA:

OTC:

PRUF:

GFR:	102045543(F11)

FAB:	101814154(KLKB1)

OMA:

PHI:

PMAJ:

CCAE:

CCW:	104690592(KLKB1)

CBRC:

103622482

ETL:

114067778

ZAB:	102073697(KLKB1)

ACHL:

103809042

SVG:

106861361

MMEA:

130575960(KLKB1)

HRT:

120753014

FPG:	101918416(F11)

FCH:

CLV:

EGZ:

NNI:

PCRI:

PLET:

EHS:

PCAO:

ACUN:

TALA:

PADL:

AFOR:

ACHC:

HALD:

HLE:

AGEN:

GCL:

CCRI:

CSTI:

CMAC:

MUI:

BREG:

FGA:

GSTE:

LDI:

MNB:

OHA:

NNT:

SHAB:

DPUB:

PGUU:

ACAR:

CPEA:

AVIT:

CVF:

RTD:

CUCA:

TEO:

BRHI:

AAM:

AROW:

NPD:

TGT:

DNE:

SCAM:

104145249(KLKB1)

ASN:	102385242(KLKB1)

AMJ:	102566272(KLKB1)

CPOO:

109322021

GGN:	109303759(KLKB1)

PSS:

102455335

CCAY:

125636019

CPIC:

101952530(KLKB1)

TST:	117878095(KLKB1)

CABI:

116835912

MRV:

120406388

ACS:	100557428(klkb1)

ASAO:

132776686(KLKB1)

PVT:	110077890(KLKB1)

SUND:

121931138(KLKB1)

PBI:	103051995(KLKB1)

PMUR:

107302682

CTIG:

120316639(KLKB1)

TSR:	106542021(KLKB1)

PGUT:

117680187(KLKB1)

APRI:

131203421(KLKB1)

PTEX:

113434569(KLKB1)

NSS:

113411769

VKO:	123036510(KLKB1)

PMUA:

114604642(KLKB1)

PRAF:

128420683(KLKB1)

ZVI:	118084140(KLKB1)

HCG:

128328487

GJA:	107121980(KLKB1)

STOW:

125440103(KLKB1)

EMC:	129336665(KLKB1)

XLA:	446603(klkb1.L)

XTR:	100486524(klkb1)

NPR:

108784940

RTEM:

120921901

BBUF:

120990165(KLKB1)

BGAR:

122934952(KLKB1)

MUO:	115462197(KLKB1)

GSH:

IPU:

IFU:

PHYP:

SMEO:

TFD:

TVC:

CMAO:

CHAR:

TNG:	GSTEN00017543G001

PFLV:

114568223

SCHU:

122864163

MZE:

101476310

ONL:	100691143 100711845 100712382

OLA:

101167304

OML:

112136310

XMA:	102235514 102236020 111610402

XCO:	114155410 114155689 114156653

XHE:	116730704 116731571

PRET:

103472119 103472120 103472122

GAF:

PPRL:

CVG:

CTUL:

GMU:	124878882 124879615

NFU:

AOCE:

MCEP:

HHIP:

HSP:

LCF:

SDU:

SLAL:

XGL:

HCQ:

ELS:

SFM:

PKI:

LOC:	102685657 107077276

LCM:	102361209(KLKB1)

LERI:

129697020

CIN:	100176588 100182205

SCLV:

120327917 120334500 120342435 120342461

APLC:

110973868 110984589

AAG:	5570931 5575054 5575060

AALB:

109426188

CQU:	CpipJ_CPIJ016225

CPII:

120419921

BIM:

100740887

BTER:

100644527

SOC:	105193897 105196026 105196044 105196739 105200420

MPHA:

105831007 105832984 114253741

AEC:	105151207 105151375

ACEP:

105617847 105619958

PBAR:

105424748

VEM:

105568413

HST:	105186338 109503706

CFO:	105249589 105251050 105251056 105255493 105257558

LHU:

105671298

PGC:	109852197 109853791

NVI:	100114471(SP16)

CSOL:

105362138 105366751

ATD:

109602881

NVL:	108559693 108563022 108565242

BMOR:

BMAN:

MSEX:

BANY:

AAGE:

HAW:

TNL:	113499223 113500559 113505544 113505545

PXY:

API:

AGS:

RMD:

BTAB:

CLEC:

FCD:	110842752 110858603

DPX:	DAPPUDRAFT_241460

PVM:	113802726 113807483 113811866 113819716

PJA:

PCHN:

HAME:

PCLA:

MNZ:

PPOI:

VDE:

VJA:

TUT:

DPTE:

DFR:	124493637 124498460

CSCU:

PTEP:

ABRU:

SDM:

LGI:	LOTGIDRAFT_153888

PCAN:

112554714 112571496

HRJ:	124289327 124291123

MYI:

110443096

PMAX:

117329014

OBI:	106870435 106877341

OSN:

115217699

LAK:

106151350

OVI:	T265_14457

NVE:

AMIL:

PDAM:

SPIS:

NGR:	NAEGRDRAFT_65585

» show all

Reference

PMID:23204305

Authors

Marques PI, Bernardino R, Fernandes T, Green ED, Hurle B, Quesada V, Seixas S

Title

Birth-and-death of KLK3 and KLK2 in primates: evolution driven by reproductive biology.

Journal

Genome Biol Evol 4:1331-8 (2012)
DOI:10.1093/gbe/evs111

Reference

PMID:11031105

Authors

Yu H, Anderson PJ, Freedman BI, Rich SS, Bowden DW

Title

Genomic structure of the human plasma prekallikrein gene, identification of allelic variants, and analysis in end-stage renal disease.

Journal

Genomics 69:225-34 (2000)
DOI:10.1006/geno.2000.6330

Sequence

[hsa:3818]

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (11)   
   KEGG DRUG (11)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (1791)   
   KEGG GENES (418)   
   KEGG MGENES (110)   
   RefGene (1248)   
   OC (15)   
Literature (2)   
   PubMed (2)   
All databases (1811)   

Download RDF

DBGET integrated database retrieval system