KEGG   ORTHOLOGY: K01380Help
Entry
K01380                      KO                                     

Name
REN
Definition
renin [EC:3.4.23.15]
Pathway
ko04614  Renin-angiotensin system
ko04924  Renin secretion
Disease
H00541  Autosomal dominant tubulointerstitial kidney disease (ADTKD)
H00575  Renal tubular dysgenesis
H02011  Familial juvenile hyperuricemic nephropathy (HNFJ)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Endocrine system
   04924 Renin secretion
    K01380  REN; renin
   04614 Renin-angiotensin system
    K01380  REN; renin
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.15  renin
     K01380  REN; renin
Peptidases [BR:ko01002]
 Aspartic Peptidases
  Family A1: pepsin family
   K01380  REN; renin
BRITE hierarchy
Genes
HSA: 5972(REN)
PTR: 469651(REN)
PPS: 100984353(REN)
GGO: 101130437(REN)
PON: 100435070(REN)
NLE: 100592810(REN)
MCC: 574299(REN)
MCF: 102122446(REN)
CSAB: 103230256(REN)
RRO: 104667395(REN)
RBB: 108535194(REN)
CJC: 100399036(REN)
SBQ: 101036357(REN)
MMU: 19701(Ren1) 19702(Ren2)
RNO: 24715(Ren)
CGE: 100763117(Ren)
NGI: 103731872(Ren)
HGL: 101725618(Ren)
CCAN: 109698788(Ren)
OCU: 100358545(REN)
TUP: 102486665(REN)
CFA: 403838(REN)
AML: 100470089(REN)
UMR: 103657747(REN)
ORO: 101380830(REN)
FCA: 101081695(REN)
PTG: 102965512(REN)
AJU: 106972902(REN)
BTA: 280909(REN)
BOM: 102267598(REN)
BIU: 109570766(REN)
PHD: 102320122(REN)
CHX: 102190154(REN)
OAS: 443310(REN)
SSC: 100524822(REN)
CFR: 102506297(REN)
CDK: 105098650(REN)
BACU: 103009645(REN)
LVE: 103068873(REN)
OOR: 101284037(REN)
ECB: 100054248(REN)
EPZ: 103557494(REN)
EAI: 106822997(REN)
MYB: 102262750(REN)
MYD: 102762390(REN)
HAI: 109386469(REN)
RSS: 109434463(REN)
PALE: 102898369(REN)
LAV: 100653930(REN)
TMU: 101361683
MDO: 100017048
SHR: 100935150(REN)
OAA: 100092330(CTSE)
GGA: 431167(REN)
MGP: 100544109(REN)
CJO: 107324665(REN)
APLA: 101800278(REN)
ACYG: 106041262(REN)
GFR: 102032412(REN)
FAB: 101811288(REN)
PHI: 102103389(REN)
PMAJ: 107214777(REN)
FPG: 101916979(REN)
FCH: 102049731(REN)
CLV: 102093221(REN)
EGZ: 104125792(REN)
AAM: 106484864(REN)
ASN: 102387440(REN)
AMJ: 102563732(REN)
PSS: 102463928(REN)
CMY: 102937199(REN)
CPIC: 101934640(REN)
ACS: 100557560(ren)
PVT: 110081398(REN)
PBI: 103048990(REN)
GJA: 107107084(REN)
XLA: 108709447(ren.S)
XTR: 100487524(ren)
NPR: 108804894(REN)
DRE: 405786(ren)
SANH: 107683898 107702841(ren)
IPU: 108265134(ren)
AMEX: 103036504
TRU: 777957(ren)
LCO: 104927909(ren)
NCC: 104956331(ren)
MZE: 101472021
OLA: 101168210
XMA: 102237116(ren)
PRET: 103467540(ren)
NFU: 107391136(ren)
CSEM: 103385502(ctse)
LCF: 108889478
HCQ: 109528441
BPEC: 110158062
ELS: 105007023
SFM: 108940277(ren)
LCM: 102363906(REN)
CMK: 103182446(ren)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3516796
  Authors
Soubrier F, Panthier JJ, Houot AM, Rougeon F, Corvol P
  Title
Segmental homology between the promoter region of the human renin gene and the mouse ren1 and ren2 promoter regions.
  Journal
Gene 41:85-92 (1986)
DOI:10.1016/0378-1119(86)90270-2
Reference
PMID:1608447
  Authors
Dhanaraj V, Dealwis CG, Frazao C, Badasso M, Sibanda BL, Tickle IJ, Cooper JB, Driessen HP, Newman M, Aguilar C, et al.
  Title
X-ray analyses of peptide-inhibitor complexes define the structural basis of specificity for human and mouse renins.
  Journal
Nature 357:466-72 (1992)
DOI:10.1038/357466a0

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