KEGG   ORTHOLOGY: K01380Help
Entry
K01380                      KO                                     

Name
REN
Definition
renin [EC:3.4.23.15]
Pathway
Renin-angiotensin system
Disease
H00541  
Uromodulin-associated kidney diseases
H00575  
Renal tubular dysgenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Endocrine system
   04614 Renin-angiotensin system
    K01380  REN; renin
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.15  renin
     K01380  REN; renin
Peptidases [BR:ko01002]
 Aspartic Peptidases
  Family A1: pepsin family
   K01380  REN; renin
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5972(REN)
PTR: 
469651(REN)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
574299(REN)
MCF: 
CJC: 
MMU: 
19701(Ren1) 19702(Ren2)
RNO: 
24715(Ren)
CGE: 
HGL: 
TUP: 
CFA: 
403838(REN)
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
280909(REN)
BOM: 
PHD: 
CHX: 
OAS: 
443310(REN)
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
431167(REN)
APLA: 
FAB: 
PHI: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XTR: 
DRE: 
405786(ren)
TRU: 
777957(ren)
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3516796
  Authors
Soubrier F, Panthier JJ, Houot AM, Rougeon F, Corvol P
  Title
Segmental homology between the promoter region of the human renin gene and the mouse ren1 and ren2 promoter regions.
  Journal
Gene 41:85-92 (1986)
Reference
PMID:1608447
  Authors
Dhanaraj V, Dealwis CG, Frazao C, Badasso M, Sibanda BL, Tickle IJ, Cooper JB, Driessen HP, Newman M, Aguilar C, et al.
  Title
X-ray analyses of peptide-inhibitor complexes define the structural basis of specificity for human and mouse renins.
  Journal
Nature 357:466-72 (1992)

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