KEGG   ORTHOLOGY: K01398Help
Entry
K01398                      KO                                     

Name
MMP2
Definition
matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
Pathway
Leukocyte transendothelial migration
GnRH signaling pathway
Estrogen signaling pathway
Pathways in cancer
Proteoglycans in cancer
Bladder cancer
Disease
H00025  
Penile cancer
H00028  
Choriocarcinoma
H00472  
Torg-Winchester syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04670 Leukocyte transendothelial migration
    K01398  MMP2; matrix metalloproteinase-2 (gelatinase A)
  Endocrine system
   04912 GnRH signaling pathway
    K01398  MMP2; matrix metalloproteinase-2 (gelatinase A)
   04915 Estrogen signaling pathway
    K01398  MMP2; matrix metalloproteinase-2 (gelatinase A)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K01398  MMP2; matrix metalloproteinase-2 (gelatinase A)
   05205 Proteoglycans in cancer
    K01398  MMP2; matrix metalloproteinase-2 (gelatinase A)
   05219 Bladder cancer
    K01398  MMP2; matrix metalloproteinase-2 (gelatinase A)
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.24  gelatinase A
     K01398  MMP2; matrix metalloproteinase-2 (gelatinase A)
Peptidases [BR:ko01002]
 Metallo Peptidases
  Family M10
   K01398  MMP2; matrix metalloproteinase-2 (gelatinase A)
Cell adhesion molecules and their ligands [BR:ko04516]
 2. Integrin Family
  Beta3 integrins
   VNR
    ITGB3; integrin beta 3
     K01398 MMP2; matrix metalloproteinase-2 (gelatinase A)
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
4313(MMP2)
PTR: 
454094(MMP2)
PPS: 
100970966(MMP2)
GGO: 
101147102(MMP2)
PON: 
100451667(MMP2)
NLE: 
100597186(MMP2)
MCC: 
698478(MMP2)
MCF: 
CJC: 
100387448(MMP2)
MMU: 
17390(Mmp2)
RNO: 
81686(Mmp2)
CGE: 
100774744(Mmp2)
NGI: 
103731682(Mmp2)
HGL: 
101696977(Mmp2)
OCU: 
100009000(MMP2)
TUP: 
102483061(MMP2)
CFA: 
403733(MMP2)
AML: 
100476183(MMP2)
UMR: 
103673901(MMP2)
FCA: 
101098838(MMP2)
PTG: 
102956398(MMP2)
BTA: 
282872(MMP2)
BOM: 
102269336(MMP2)
PHD: 
102315493(MMP2)
CHX: 
102184364(MMP2)
OAS: 
443115(MMP2)
SSC: 
397391(MMP2)
CFR: 
BACU: 
103016736(MMP2)
LVE: 
103071760(MMP2)
ECB: 
100033948(MMP2)
MYB: 
102260608(MMP2)
MYD: 
102767174(MMP2)
PALE: 
102883808(MMP2)
MDO: 
100020585(MMP2)
SHR: 
100935012(MMP2)
OAA: 
100077120(MMP2)
GGA: 
386583(MMP2)
MGP: 
100125331(MMP2)
APLA: 
TGU: 
100228546(MMP2)
FAB: 
101815345(MMP2)
PHI: 
102107059(MMP2)
FPG: 
101924896(MMP2)
FCH: 
102056005(MMP2)
CLV: 
102092170(MMP2)
ASN: 
102372370(MMP2)
AMJ: 
102574302(MMP2)
PSS: 
102463152(MMP2)
CMY: 
102946066(MMP2)
ACS: 
100557569(mmp2)
PBI: 
XLA: 
380389(mmp2)
XTR: 
548506(mmp2)
DRE: 
337179(mmp2)
TRU: 
653022(mmp-2)
MZE: 
OLA: 
100125419(gel-a)
XMA: 
LCM: 
102350008(MMP2)
CMK: 
103176101(mmp2)
CIN: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Fanjul-Fernandez M, Folgueras AR, Cabrera S, Lopez-Otin C
  Title
Matrix metalloproteinases: evolution, gene regulation and functional analysis in  mouse models.
  Journal
Biochim Biophys Acta 1803:3-19 (2010)
Reference
  Authors
Amalinei C, Caruntu ID, Balan RA
  Title
Biology of metalloproteinases.
  Journal
Rom J Morphol Embryol 48:323-34 (2007)

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