KEGG   ORTHOLOGY: K01528Help
Entry
K01528                      KO                                     

Name
DNM
Definition
dynamin GTPase [EC:3.6.5.5]
Pathway
ko04072  Phospholipase D signaling pathway
ko04144  Endocytosis
ko04721  Synaptic vesicle cycle
ko04961  Endocrine and other factor-regulated calcium reabsorption
ko05100  Bacterial invasion of epithelial cells
Disease
H00264  Charcot-Marie-Tooth disease (CMT)
H00606  Early infantile epileptic encephalopathy
H00700  Centronuclear myopathy
H00865  Lethal congenital contractural syndrome (LCCS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04072 Phospholipase D signaling pathway
    K01528  DNM; dynamin GTPase
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K01528  DNM; dynamin GTPase
 Organismal Systems
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    K01528  DNM; dynamin GTPase
  Nervous system
   04721 Synaptic vesicle cycle
    K01528  DNM; dynamin GTPase
 Human Diseases
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    K01528  DNM; dynamin GTPase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.5  Acting on GTP to facilitate cellular and subcellular movement
    3.6.5.5  dynamin GTPase
     K01528  DNM; dynamin GTPase
Membrane trafficking [BR:ko04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Dynamin
    K01528  DNM; dynamin GTPase
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    K01528  DNM; dynamin GTPase
   RhoA-dependent endocytosis
    K01528  DNM; dynamin GTPase
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K01528  DNM; dynamin GTPase
BRITE hierarchy
Genes
HSA: 1759(DNM1) 1785(DNM2) 26052(DNM3)
PTR: 107976786(DNM1) 455718(DNM2) 457514(DNM3)
PPS: 100967261(DNM3) 100971753 100972812(DNM2) 100991525(DNM1) 100995231
GGO: 101130050(DNM1) 101133474(DNM3) 101138473(DNM2) 109023457 109025382 109025449
PON: 100431942(DNM3) 100442734(DNM2) 100446863(DNM1)
NLE: 100590132(DNM2) 100594555(DNM3) 100599465(DNM1) 105739874
MCC: 705300(DNM3) 713558(DNM2) 717697(DNM1)
MCF: 102118932(DNM2) 102130665(DNM1) 102135212(DNM3)
CSAB: 103230583(DNM3) 103233911(DNM2) 103239806(DNM1)
RRO: 104665858(DNM1) 104668539 104669594 104670461(DNM2) 104678473
RBB: 108512814(DNM1) 108522812 108522813(DNM2) 108526256(DNM3)
CJC: 100388870(DNM1) 100406310(DNM3) 100412229(DNM2)
SBQ: 101038089(DNM1) 101038308(DNM3) 101039773(DNM2)
MMU: 103967(Dnm3) 13429(Dnm1) 13430(Dnm2)
RNO: 140694(Dnm1) 171574(Dnm3) 25751(Dnm2)
CGE: 100753867(Dnm1) 100771373(Dnm2) 100772324(Dnm3)
NGI: 103727516(Dnm1) 103746355(Dnm3) 103747545(Dnm2)
HGL: 101696596(Dnm2) 101699561(Dnm1) 101700676(Dnm3)
OCU: 100346468(DNM3) 100348451(DNM2) 100355909(DNM1) 108176538
TUP: 102469489(DNM3) 102473910(DNM2) 102477586(DNM1)
CFA: 484949(DNM2) 490341(DNM3) 491319(DNM1)
AML: 100466002(DNM2) 100470165(DNM1) 100471013(DNM3)
UMR: 103669226(DNM3) 103670446 103678718(DNM2)
ORO: 101364734(DNM1) 101381055(DNM2) 101382196(DNM3)
FCA: 101090983(DNM3) 101100788(DNM2) 654421(DNM1)
PTG: 102954615(DNM1) 102959946(DNM3) 102965772(DNM2)
AJU: 106966310(DNM1) 106979840(DNM3) 106983916(DNM2)
BTA: 506315(DNM3) 508794(DNM1) 511691(DNM2)
BOM: 102266987(DNM1) 102279295(DNM3) 102279431(DNM2)
BIU: 109560938 109561599(DNM2) 109566503(DNM1) 109570608(DNM3)
PHD: 102320807(DNM3) 102332624(DNM2) 102338993(DNM1)
CHX: 102177079(DNM3) 102189492(DNM1) 102190402(DNM2)
OAS: 101107117(DNM3) 101108737(DNM1) 101115027(DNM2)
SSC: 100153921(DNM1) 100622420(DNM3) 100622538(DNM2)
CFR: 102504580(DNM1) 102505802(DNM2) 102512039 102522953(DNM3)
CDK: 105087624(DNM2) 105092581(DNM1) 105092767(DNM3)
BACU: 102997247(DNM3) 102999147(DNM1) 103012443(DNM2)
LVE: 103074090(DNM3) 103085901(DNM2) 103090124(DNM1)
OOR: 101271351(DNM3) 101275337(DNM1) 101281266(DNM2)
ECB: 100057627(DNM2) 100060156(DNM3) 100070282(DNM1)
EPZ: 103550849(DNM1) 103554258(DNM3) 103562422(DNM2) 103565071
EAI: 106833823(DNM3) 106845444(DNM1) 106846633(DNM2)
MYB: 102252356(DNM2) 102259504(DNM3) 102262334(DNM1)
MYD: 102755663(DNM2) 102757829(DNM1) 102768644(DNM3)
HAI: 109380059(DNM1) 109385578(DNM3) 109391601(DNM2)
PALE: 102884852(DNM1) 102890780(DNM2) 102892080(DNM3)
MDO: 100011387(DNM2) 100012623(DNM1) 100015400(DNM3)
OAA: 100084643(DNM3) 100086764(DNM2) 100086937
GGA: 417217(DNM1) 424389(DNM3) 430067
MGP: 100538944 100544930(DNM1)
CJO: 107307556 107317224(DNM3) 107321790(DNM1)
APLA: 101792324(DNM1) 101793680 101801487(DNM3)
ACYG: 106029339 106041566(DNM3) 106047297(DNM1)
TGU: 100221801(DNM3) 100222436(DNM1)
GFR: 102031566(DNM3) 102034785(DNM1) 102044497(DNM2)
FAB: 101805981(DNM3) 101812939 101819062(DNM1)
PMAJ: 107208128(DNM3) 107211993(DNM1)
CCW: 104688460(DNM1) 104695448(DNM3)
FPG: 101911473(DNM3) 101912266(DNM2) 101923112(DNM1)
FCH: 102047099(DNM3) 102049966(DNM2) 102055649(DNM1)
CLV: 102084075(DNM3) 102085152 102087004(DNM1)
EGZ: 104122224(DNM1) 104127246 104132109(DNM3)
AAM: 106492246(DNM2) 106495466(DNM1) 106499244(DNM3)
ASN: 102373892(DNM1) 102384061 102386721(DNM3) 102388259(DNM2)
AMJ: 102557986(DNM3) 102572795(DNM2) 106737069(DNM1)
PSS: 102454954(DNM2) 102460210(DNM3) 102460911(DNM1)
CMY: 102930568(DNM3) 102933091(DNM2) 102945038(DNM1)
CPIC: 101934411(DNM1) 101935482(DNM2) 101951128 101951995(DNM3)
ACS: 100556614(dnm1) 100562272(dnm2)
PVT: 110078022(DNM2) 110078828(DNM1)
PBI: 103056805(DNM1) 103057909(DNM2)
GJA: 107109757(DNM2) 107111402 107113577(DNM1)
XTR: 100489905(dnm3) 448130(dnm1) 496487(dnm2)
NPR: 108793097(DNM1) 108795568(DNM3) 108797846(DNM2)
DRE: 100307098(dnm1a) 100333543(dnm1b) 406525(dnm2b) 559334(dnm2a)
LCM: 102353009(DNM1) 102359584(DNM2) 102366012(DNM3)
CMK: 103174368 103180079(dnm3) 103183065(dnm1)
CIN: 100184166
SPU: 765161
APLC: 110976283
DME: Dmel_CG18102(shi)
DSI: Dsimw501_GD17250(Dsim_shi)
MDE: 101894249
AAG: 5569014
AME: 410923(shi)
BIM: 100741278
AEC: 105146608
ACEP: 105627679
PBAR: 105426994
HST: 105189960
CFO: 105250093
LHU: 105668143
PGC: 109860000
NVI: 100120115
TCA: 657469
NVL: 108561411
BMOR: 101735699
PMAC: 106719569
PRAP: 111002647
PXY: 105393043
API: 100168088(Dnm1)
DNX: 107166728
ZNE: 110831233
TUT: 107361790
CEL: CELE_C02C6.1(dyn-1)
CBR: CBG07725(Cbr-dyn-1)
BMY: Bm1_01485
MYI: 110442468
OBI: 106867485
LAK: 106179519
EPA: 110244508
ADF: 107349303
HMG: 100199205(dnm1)
ATH: AT1G10290(ADL6) AT1G59610(DL3)
LJA: Lj0g3v0117369.1(Lj0g3v0117369.1) Lj0g3v0169099.1(Lj0g3v0169099.1) Lj0g3v0199559.2(Lj0g3v0199559.2) Lj0g3v0248499.1(Lj0g3v0248499.1) Lj0g3v0330799.1(Lj0g3v0330799.1) Lj3g3v0462040.1(Lj3g3v0462040.1) Lj3g3v0462310.1(Lj3g3v0462310.1) Lj3g3v0618160.2(Lj3g3v0618160.2) Lj3g3v2442000.1(Lj3g3v2442000.1) Lj3g3v2442000.2(Lj3g3v2442000.2) Lj4g3v0000080.1(Lj4g3v0000080.1)
PPER: 18768866
PAVI: 110746015
BVG: 104897029
SOE: 110777327
DOSA: Os01t0681100-01(Os01g0681100) Os02t0738900-01(Os02g0738900) Os06t0247800-01(Os06g0247800) Os08t0425100-01(Os08g0425100)
ATS: 109735915(LOC109735915) 109744320(LOC109744320) 109783600(LOC109783600)
CRE: CHLREDRAFT_195428(DRP2)
VCN: VOLCADRAFT_106572(drp2)
MNG: MNEG_1383
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ramachandran R
  Title
Vesicle scission: dynamin.
  Journal
Semin Cell Dev Biol 22:10-7 (2011)
DOI:10.1016/j.semcdb.2010.09.001
Reference
  Authors
Marks B, Stowell MH, Vallis Y, Mills IG, Gibson A, Hopkins CR, McMahon HT
  Title
GTPase activity of dynamin and resulting conformation change are essential for endocytosis.
  Journal
Nature 410:231-5 (2001)
DOI:10.1038/35065645
  Sequence
[hsa:1759]

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