KEGG ORTHOLOGY: K01623

ORTHOLOGY: K01623

Entry

K01623 KO

Name

ALDO

Definition

fructose-bisphosphate aldolase, class I [EC:4.1.2.13]

Pathway

ko00010	Glycolysis / Gluconeogenesis
ko00030	Pentose phosphate pathway
ko00051	Fructose and mannose metabolism
ko00680	Methane metabolism
ko00710	Carbon fixation in photosynthetic organisms

Module

M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00003	Gluconeogenesis, oxaloacetate => fructose-6P
M00165	Reductive pentose phosphate cycle (Calvin cycle)
M00167	Reductive pentose phosphate cycle, glyceraldehyde-3P => RuBP

Disease

H00069	Glycogen storage diseases (GSD)
H00071	Hereditary fructose intolerance

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    K01623  ALDO; fructose-bisphosphate aldolase, class I
   00030 Pentose phosphate pathway
    K01623  ALDO; fructose-bisphosphate aldolase, class I
   00051 Fructose and mannose metabolism
    K01623  ALDO; fructose-bisphosphate aldolase, class I
  Energy metabolism
   00710 Carbon fixation in photosynthetic organisms
    K01623  ALDO; fructose-bisphosphate aldolase, class I
   00680 Methane metabolism
    K01623  ALDO; fructose-bisphosphate aldolase, class I
KEGG pathway modules [BR:ko00002]
Pathway module
  Energy metabolism
   Carbon fixation
    M00165  Reductive pentose phosphate cycle (Calvin cycle)
     K01623  ALDO; fructose-bisphosphate aldolase, class I
    M00167  Reductive pentose phosphate cycle, glyceraldehyde-3P => RuBP
     K01623  ALDO; fructose-bisphosphate aldolase, class I
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
     K01623  ALDO; fructose-bisphosphate aldolase, class I
    M00003  Gluconeogenesis, oxaloacetate => fructose-6P
     K01623  ALDO; fructose-bisphosphate aldolase, class I
Enzymes [BR:ko01000]
4. Lyases
  4.1  Carbon-carbon lyases
   4.1.2  Aldehyde-lyases
    4.1.2.13  fructose-bisphosphate aldolase
     K01623  ALDO; fructose-bisphosphate aldolase, class I
Chromosome [BR:ko03036]
Eukaryotic Type
  Centrosomal proteins
   Other centrosome associated proteins
    K01623  ALDO; fructose-bisphosphate aldolase, class I

Other DBs

RN:

R01068 R01070 R01829 R02568

COG:

COG3588

GO:

0004332

Genes

HSA:	226(ALDOA) 229(ALDOB) 230(ALDOC)
PTR:	454362(ALDOA) 464623(ALDOB) 493951(ALDOC)
PPS:	100984644(ALDOC) 100993015(ALDOB) 100995352(ALDOA)
GGO:	101127231(ALDOA) 101134921(ALDOC) 101141669(ALDOB)
PON:	100174098(ALDOA) 100174217(ALDOB) 100441024 100446169(ALDOC)
MCC:	708406(ALDOA) 709213(ALDOC) 713818(ALDOB)
MMU:	11674(Aldoa) 11676(Aldoc) 230163(Aldob) 353204(Aldoart1)
RNO:	24189(Aldoa) 24190(Aldob) 24191(Aldoc) 299052(Aldoart1)
CFA:	474787(ALDOB) 479787(ALDOA) 480622(ALDOC)
AML:	100466882 100475506 100478103
FCA:	101097025(ALDOB) 101098666(ALDOC) 101100776(ALDOA)
BTA:	504584(ALDOC) 509566(ALDOA) 515263(ALDOB)
SSC:	100512013(ALDOC)
ECB:	100054480(ALDOB) 100059231(ALDOC) 100066121(ALDOA)
MDO:	100014226 100017515 100017820 100019791
SHR:	100922025 100925451(ALDOC) 100933117(ALDOA)
OAA:	100074678 100090188
GGA:	395492(ALDOC) 427308(ALDOB)
MGP:	100538763 100540715
TGU:	100227328(ALDOB)
ACS:	100557186 100557803 100567097
XLA:	100037142 379254(xaldb) 379336(aldoa) 379489 380079(aldoc) 398623(aldob)
XTR:	394736(aldob) 407969(aldoc) 448112(aldoa)
DRE:	321664(aldob) 336425(aldoaa) 369193(aldocb) 406496(aldoab) 792692(aldoca)
TRU:	101070601 101071185 101075981 101077944
OLA:	100049249(aldoa) 100049250(aldoc) 100049273(aldob) 101163920
BFO:	BRAFLDRAFT_91860
CIN:	100178673
SPU:	548623 592868
DME:	Dmel_CG5432 Dmel_CG6058(Ald)
DPO:	Dpse_GA18877 Dpse_GA19329
DAN:	Dana_GF16038 Dana_GF20732
DER:	Dere_GG11473 Dere_GG12193
DPE:	Dper_GL21844
DSE:	Dsec_GM10189 Dsec_GM10318
DSI:	Dsim_GD18141 Dsim_GD21278
DWI:	Dwil_GK13312 Dwil_GK13316
DYA:	Dyak_GE10635 Dyak_GE23665
DGR:	Dgri_GH18178 Dgri_GH19415
DMO:	Dmoj_GI10131 Dmoj_GI22619
DVI:	Dvir_GJ23350 Dvir_GJ23865
AGA:	AgaP_AGAP002564
AAG:	AaeL_AAEL005766
CQU:	CpipJ_CPIJ009571
AME:	550785 725455
NVI:	100118253(NV16284)
API:	100166128
PHU:	Phum_PHUM609020
ISC:	IscW_ISCW011371
CEL:	CELE_F01F1.12(aldo-2) CELE_T05D4.1(aldo-1)
CBR:	CBG09060 CBG15316
BMY:	Bm1_09045 Bm1_15350
TSP:	Tsp_09639
SMM:	Smp_042160.1 Smp_042160.2
NVE:	NEMVE_v1g244812
HMG:	100206076
TAD:	TRIADDRAFT_38271
AQU:	100631718 100640992
ATH:	AT2G01140 AT2G21330(FBA1) AT2G36460 AT3G52930 AT4G26520 AT4G26530 AT4G38970(FBA2) AT5G03690
ALY:	ARALYDRAFT_482625 ARALYDRAFT_484021 ARALYDRAFT_490667 ARALYDRAFT_492157 ARALYDRAFT_492160 ARALYDRAFT_900547 ARALYDRAFT_906673
GMX:	100527532 100775844 100776915 100778363 100783089 100786504 100792394 100795446 100798677 100802732 100815070 100818383 100818915 547751(FBA)
MTR:	MTR_4g071860 MTR_4g071880 MTR_5g096670
CSV:	101204323 101209429 101218080 101219476 101224210 101228351 101229065
RCU:	RCOM_0291680 RCOM_0383870 RCOM_0577600 RCOM_1180710 RCOM_1450320 RCOM_1538490
POP:	POPTR_578574 POPTR_708143 POPTR_713130 POPTR_744909 POPTR_802978 POPTR_822107 POPTR_832739 POPTR_833033 POPTR_836979
VVI:	100245998 100262354 100265177 100267988 100852851
OSA:	4325027 4326074 4338737 4341496 4344545 4349897
DOSA:	Os01t0118000-01(Os01g0118000) Os01t0905800-01(Os01g0905800) Os05t0402700-01(Os05g0402700) Os06t0608700-01(Os06g0608700) Os08t0120600-01(Os08g0120600) Os10t0163340-01(Os10g0163340) Os11t0171300-01(Os11g0171300)
BDI:	100825584 100832935 100834905 100836194
SBI:	SORBI_03g008050(SORBIDRAFT_03g008050) SORBI_03g043140(SORBIDRAFT_03g043140) SORBI_04g019020(SORBIDRAFT_04g019020) SORBI_05g004590(SORBIDRAFT_05g004590) SORBI_08g004500(SORBIDRAFT_08g004500) SORBI_10g023850(SORBIDRAFT_10g023850)
ZMA:	100272845(AY110170) 100273196(IDP1438) 100283676 100286050 542261(ald1)
SMO:	SELMODRAFT_176914 SELMODRAFT_227983 SELMODRAFT_231316 SELMODRAFT_267384 SELMODRAFT_425653
PPP:	PHYPADRAFT_120582 PHYPADRAFT_124602 PHYPADRAFT_140886 PHYPADRAFT_148638 PHYPADRAFT_155603 PHYPADRAFT_166170 PHYPADRAFT_232361 PHYPADRAFT_233547 PHYPADRAFT_56578
CRE:	CHLREDRAFT_152892(FBA1) CHLREDRAFT_196304(FBA4) CHLREDRAFT_24459(FBA3) CHLREDRAFT_29185(FBA2)
VCN:	VOLCADRAFT_69480 VOLCADRAFT_79447 VOLCADRAFT_82483 VOLCADRAFT_83313
OLU:	OSTLU_13796 OSTLU_33820
OTA:	Ot01g03020(fbaI) Ot03g00610(fbaI)
CME:	CME145C CMI049C
MPR:	MPER_07595
ECU:	ECU01_0240
EIN:	Eint_010110
EHE:	EHEL_010100
NCE:	NCER_100242
NGR:	NAEGRDRAFT_56383
DDI:	DDB_G0274375(fba)
DPP:	DICPUDRAFT_49487
PFA:	PF14_0425
PFD:	PFDG_04161
PFH:	PFHG_01727
PYO:	PY03709
PCB:	PC001392.02.0
PBE:	PB000757.02.0
PKN:	PKH_126150
PVX:	PVX_118255
PCY:	PCYB_127030
TAN:	TA20060
TPV:	TP01_0101
BBO:	BBOV_IV000790(21.m03045)
CPV:	cgd1_3020
CHO:	Chro.10335
TGO:	TGME49_036040 TGME49_036050
TET:	TTHERM_00487090
PTM:	GSPATT00023218001 GSPATT00023967001 GSPATT00025729001 GSPATT00026594001
TBR:	Tb10.70.1370
TCR:	504163.40 504163.50 510301.10 510301.20
LMA:	LMJF_36_1260(ALD)
LIF:	LINJ_36_1320(ALD)
LDO:	LDBPK_361320
LMI:	LMXM_36_1260
LBZ:	LBRM_35_1390
PTI:	PHATRDRAFT_42447(Fba4) PHATRDRAFT_51289(FbaC5)
TPS:	THAPSDRAFT_11761(ALDO4)
XFA:	XF0826
XFT:	PD1845(fbaB)
XFM:	Xfasm12_2023
XFN:	XfasM23_1946
XFF:	XFLM_03680
XCC:	XCC3185
XCB:	XC_0979
XCA:	xccb100_0991(fba)
XCV:	XCV3462(fbaB)
XCP:	XCR_3526
XAC:	XAC3344
XAX:	XACM_3233(fbaB)
XAO:	XAC29_17040
XOO:	XOO3412
XOM:	XOO_3212
XOP:	PXO_02119
XOR:	XOC_3585
XAL:	XALc_2301
XCI:	XCAW_04037
SML:	Smlt3797(alf1)
SMT:	Smal_3213
BUJ:	BurJV3_3242
SMZ:	SMD_3400(alf1)
PSU:	Psesu_0062 Psesu_2402
PSD:	DSC_00795 DSC_13105
FAU:	Fraau_0396
RHD:	R2APBS1_0553
PAR:	Psyc_0085
PCR:	Pcryo_0092
PRW:	PsycPRwf_2273
PHA:	PSHAb0548
PAT:	Patl_3327
MAQ:	Maqu_1058
MHC:	MARHY2220
MAD:	HP15_1400(aldOB)
MBS:	MRBBS_0911
AMC:	MADE_1004360
AMAC:	MASE_03585
AMB:	AMBAS45_03980
AMG:	AMEC673_03830
AMK:	AMBLS11_03785
AMAA:	amad1_04080
ALT:	ambt_14385
GAG:	Glaag_1024
GNI:	GNIT_2727
GPS:	C427_1514
PIN:	Ping_2682
PSY:	PCNPT3_07800
LPN:	lpg0470
LPU:	LPE509_02750
LPF:	lpl0511
LPP:	lpp0535
LPC:	LPC_2874(alf1)
LPA:	lpa_00720
LPE:	lp12_0473
LLO:	LLO_2717
NWA:	Nwat_0418
TKM:	TK90_1149
TNI:	TVNIR_3070
MMW:	Mmwyl1_1951
REU:	Reut_B4512
REH:	H16_B0278(fbaB)
CTI:	RALTA_B0294
CNC:	CNE_2c03050(fbaB)
BUR:	Bcep18194_B0565
BXE:	Bxe_B1334
BPH:	Bphy_3578
BPY:	Bphyt_2128
BUG:	BC1001_3634
BGE:	BC1002_3891
BGF:	BC1003_3693
BYI:	BYI23_D009890
BPX:	BUPH_00206
POL:	Bpro_4741
VAP:	Vapar_2993
VPE:	Varpa_2645
CFU:	CFU_2568(fbaB)
NET:	Neut_1996
NMU:	Nmul_A1561
TBD:	Tbd_1513
DAT:	HRM2_07620(fba1)
CCX:	COCOR_01449
PUB:	SAR11_0584(fbaB)
PEL:	SAR11G3_01433
MLO:	mlr3754
MCI:	Mesci_1393
MOP:	Mesop_1415
MAM:	Mesau_01432
MES:	Meso_3436
PLA:	Plav_2105
SME:	SMc03983(fbaB)
SMK:	Sinme_2822
SMQ:	SinmeB_2598
SMX:	SM11_chr2932(fbaB)
SMI:	BN406_02625(fbaB) BN406_06665(fda)
SMEG:	C770_GR4Chr2892
SMEL:	SM2011_c03983(fbaB)
SMD:	Smed_2654
RHI:	NGR_c28100(fbaB)
SFH:	SFHH103_02822(fbaB)
SFD:	USDA257_c52310
ATU:	Atu3740
ARA:	Arad_3734(fbaB)
AVI:	Avi_3652
AGR:	AGROH133_12070 AGROH133_14346
RET:	RHE_CH03500(fbaB)
REC:	RHECIAT_CH0003743(fbaB)
RLE:	RL4012
RLT:	Rleg2_3242
RLG:	Rleg_3539
RTR:	RTCIAT899_PC02930
LAS:	CLIBASIA_02695
LAA:	WSI_02700
LSO:	CKC_02060
LCC:	B488_12160
OAN:	Oant_1185
BJA:	bll1520
BJU:	BJ6T_83240
BBT:	BBta_6929
BRS:	S23_10960
RPA:	RPA0940
RPB:	RPB_4471
RPC:	RPC_4773
RPD:	RPD_4317
RPE:	RPE_4722
RPT:	Rpal_1010
RPX:	Rpdx1_1105
NWI:	Nwi_2737
NHA:	Nham_3534
OCA:	OCAR_7313
OCG:	OCA5_c08040(fbaB)
OCO:	OCA4_c08030(fbaB)
AOL:	S58_12260
BHE:	BH15060(fbaB)
BQU:	BQ11980(fbaB)
BQR:	RM11_1100
BBK:	BARBAKC583_0141(fbaB)
BGR:	Bgr_18500(fbaB)
BCD:	BARCL_1239(fbaB)
BAUS:	BAnh1_11530(fbaB)
BVN:	BVwin_13600(fbaB)
XAU:	Xaut_3077
AZC:	AZC_0501
SNO:	Snov_3072
MNO:	Mnod_3208
BID:	Bind_3466
HDN:	Hden_2447
HMC:	HYPMC_0994
PHL:	KKY_2475
SIL:	SPO1899(fda)
SIT:	TM1040_1976
RCP:	RCAP_rcc01707(fda)
JAN:	Jann_1693
RDE:	RD1_2270(fda)
RLI:	RLO149_c022480(fda)
DSH:	Dshi_2156(fda)
PGA:	PGA1_c23910(fda)
PGL:	PGA2_c21930(fda)
OAT:	OAN307_c27900(fda)
OAR:	OA238_c11070(fda)
MMR:	Mmar10_2595
HNE:	HNE_3181(fda)
HBA:	Hbal_2978
NAR:	Saro_1964
NPP:	PP1Y_AT28733
SAL:	Sala_1317
SWI:	Swit_2606
SJP:	SJA_C1-13130(fbaB)
SCH:	Sphch_1193
SSY:	SLG_23320
ELI:	ELI_05235
GOX:	GOX1540
GOH:	B932_1314
GDI:	GDI_0491(fbaB)
GDJ:	Gdia_1516
GXY:	GLX_02230
PBR:	PB2503_02727
APM:	HIMB5_00010740
BSUB:	BEST7613_5947(fda)
BCK:	BCO26_2530
BAG:	Bcoa_1843
OIH:	OB3245
SAU:	SA2399
SAV:	SAV2606
SAW:	SAHV_2590
SAH:	SaurJH1_2682
SAJ:	SaurJH9_2628
SAM:	MW2525
SAS:	SAS2491
SAR:	SAR2684(fda)
SAC:	SACOL2622(fdaB)
SAX:	USA300HOU_2599(fdaB)
SAA:	SAUSA300_2540
SAO:	SAOUHSC_02926
SAE:	NWMN_2503
SAD:	SAAV_2672(fdaB)
SUU:	M013TW_2584
SUV:	SAVC_11895
SUH:	SAMSHR1132_24210
SUE:	SAOV_2650
SUJ:	SAA6159_02502(fdaB)
SUK:	SAA6008_02663(fdaB)
SUC:	ECTR2_2460
SUT:	SAT0131_02838
SUQ:	HMPREF0772_10586(fdaB)
SUZ:	MS7_2611(fda)
SUD:	ST398NM01_2654
SUX:	SAEMRSA15_25100(fda)
SUW:	SATW20_27450(fda)
SUG:	SAPIG2654
SUF:	SARLGA251_23790(fda)
SAB:	SAB2479(fda)
SUY:	SA2981_2544
SAUB:	C248_2665(fda)
SAUM:	BN843_26420
SEP:	SE2156
SER:	SERP2166(fdaB)
SHA:	SH0450
SSP:	SSP0191
SCA:	Sca_2144(fda)
SLG:	SLGD_00388
SLN:	SLUG_03830(fda)
SSD:	SPSINT_2258
SDT:	SPSE_0210(fda)
SWA:	A284_01445
HHD:	HBHAL_4117(fdaB)
CRN:	CAR_c20700(fda)
CAC:	CA_P0064(alf)
CAE:	SMB_P063(alf)
CAY:	CEA_P0063(alf)
CBE:	Cbei_3039
FAA:	HMPREF0389_00042
ELM:	ELI_3469
AWO:	Awo_c33080(fba5)
EHA:	Ethha_0730
CLO:	HMPREF0868_0441
HAS:	Halsa_0314
SSG:	Selsp_1188
MPA:	MAP4308c
MAV:	MAV_5271
MIT:	OCO_51100
MIR:	OCQ_52090
MIA:	OCU_51030
MID:	MIP_07730
MSM:	MSMEG_3507
MSG:	MSMEI_3427
MSA:	Mycsm_03056
MVA:	Mvan_3341
MGI:	Mflv_3550
MSP:	Mspyr1_28920
MMC:	Mmcs_2704
MKM:	Mkms_2748
MJL:	Mjls_2734
MRH:	MycrhN_4628
MMM:	W7S_25620
MCB:	Mycch_2588
CKP:	ckrop_0778(fda)
MLU:	Mlut_18420
PAC:	PPA2024
PAK:	HMPREF0675_5089
PAV:	TIA2EST22_09905
PAX:	TIA2EST36_09885
PAZ:	TIA2EST2_09840
PAW:	PAZ_c21120(fda)
PAD:	TIIST44_02895
PCN:	TIB1ST10_10295
PACC:	PAC1_10325
PACH:	PAGK_1936
PFR:	PFREUD_23890(fba2)
PPC:	HMPREF9154_3053
PBO:	PACID_07280
PRA:	PALO_00880
MPH:	MLP_19620(fbaB)
NCA:	Noca_1003
PDX:	Psed_6248
STP:	Strop_4157
RXY:	Rxyl_2541
AFO:	Afer_0177
TDE:	TDE0340
SSM:	Spirs_3511
SCC:	Spico_1607
SGP:	SpiGrapes_2267
ACM:	AciX9_2524
PGI:	PG1755(fbaB)
PGN:	PGN_1695
PGT:	PGTDC60_1381(fbaB)
PAH:	Poras_1181
PHE:	Phep_3478
CHU:	CHU_1341(alf)
FJO:	Fjoh_0953
COC:	Coch_1087
FNU:	FN0322
LBA:	Lebu_1787
SYN:	slr0943(fda)
SYZ:	MYO_118460(fda)
SYY:	SYNGTS_1829(fda)
SYT:	SYNGTI_1829(fda)
SYS:	SYNPCCN_1828(fda)
SYQ:	SYNPCCP_1828(fda)
SYE:	Syncc9902_0796
SYG:	sync_1704
CYN:	Cyan7425_2028
AMR:	AM1_3372
CGC:	Cyagr_0655
DSL:	Dacsa_2850
HAO:	PCC7418_2846
GLP:	Glo7428_4904
CMP:	Cha6605_3778 Cha6605_6076
PMA:	Pro0856(fda)
PMN:	PMN2A_0188
PMB:	A9601_08451
PMC:	P9515_08001
PMF:	P9303_23391
PMH:	P9215_08761
PME:	NATL1_08201
TER:	Tery_1687
LEP:	Lepto7376_2336
PSEU:	Pse7367_1158
CPC:	Cpar_0413
CLI:	Clim_1927
PLT:	Plut_0519
PAA:	Paes_1070

» show all

Reference

PMID:9531482 (E.coli)

Authors

Thomson GJ, Howlett GJ, Ashcroft AE, Berry A.

Title

The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase.

Journal

Biochem J 331:437-45 (1998)

Reference

PMID:18000879

Authors

Oeffner F, Moch C, Neundorf A, Hofmann J, Koch M, Grzeschik KH

Title

Novel interaction partners of Bardet-Biedl syndrome proteins.

Journal

Cell Motil Cytoskeleton 65:143-55 (2008)

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Ontology (7)   
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