Entry |
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Symbol |
LSS, ERG7
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Name |
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Pathway |
map01110 | Biosynthesis of secondary metabolites |
|
Module |
M00101 | Cholesterol biosynthesis, FPP => cholesterol |
M00102 | Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol |
|
Reaction |
R03199 | (S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming) |
|
Disease |
H02303 | Alopecia-mental retardation syndrome |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
K01852 LSS, ERG7; lanosterol synthase
Enzymes [BR:ko01000]
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.7 lanosterol synthase
K01852 LSS, ERG7; lanosterol synthase
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Other DBs |
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Genes |
» show all
|
Reference |
|
Authors |
Dean PD, Ortiz de Montellano PR, Bloch K, Corey EJ |
Title |
A soluble 2,3-oxidosqualene sterol cyclase. |
Journal |
J Biol Chem 242:3014-5 (1967) |
Reference |
|
Authors |
Baker CH, Matsuda SP, Liu DR, Corey EJ |
Title |
Molecular cloning of the human gene encoding lanosterol synthase from a liver cDNA library. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Corey EJ, Matsuda SP, Bartel B |
Title |
Molecular cloning, characterization, and overexpression of ERG7, the Saccharomyces cerevisiae gene encoding lanosterol synthase. |
Journal |
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Sequence |
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Reference |
|
Authors |
Suzuki M, Xiang T, Ohyama K, Seki H, Saito K, Muranaka T, Hayashi H, Katsube Y, Kushiro T, Shibuya M, Ebizuka Y |
Title |
Lanosterol synthase in dicotyledonous plants. |
Journal |
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Sequence |
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