KEGG ORTHOLOGY: K02147

ORTHOLOGY: K02147

Entry

K02147 KO

Name

ATPeVB, ATP6B1

Definition

V-type H+-transporting ATPase subunit B [EC:3.6.3.14]

Pathway

ko00190	Oxidative phosphorylation
ko04145	Phagosome
ko04721	Synaptic vesicle cycle
ko04966	Collecting duct acid secretion
ko05110	Vibrio cholerae infection
ko05120	Epithelial cell signaling in Helicobacter pylori infection
ko05323	Rheumatoid arthritis

Module

M00160

V-type ATPase, eukaryotes

Disease

H00428

Distal renal tubular acidosis (RTA type 1)

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Energy metabolism
   00190 Oxidative phosphorylation
    K02147  ATPeVB, ATP6B1; V-type H+-transporting ATPase subunit B
Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K02147  ATPeVB, ATP6B1; V-type H+-transporting ATPase subunit B
Organismal Systems
  Excretory system
   04966 Collecting duct acid secretion
    K02147  ATPeVB, ATP6B1; V-type H+-transporting ATPase subunit B
  Nervous system
   04721 Synaptic vesicle cycle
    K02147  ATPeVB, ATP6B1; V-type H+-transporting ATPase subunit B
Human Diseases
  Immune diseases
   05323 Rheumatoid arthritis
    K02147  ATPeVB, ATP6B1; V-type H+-transporting ATPase subunit B
  Infectious diseases
   05110 Vibrio cholerae infection
    K02147  ATPeVB, ATP6B1; V-type H+-transporting ATPase subunit B
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K02147  ATPeVB, ATP6B1; V-type H+-transporting ATPase subunit B
KEGG pathway modules [BR:ko00002]
Structural complex
  Energy metabolism
   ATP synthesis
    M00160  V-type ATPase, eukaryotes
     K02147  ATPeVB, ATP6B1; V-type H+-transporting ATPase subunit B
Enzymes [BR:ko01000]
3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.3  Acting on acid anhydrides to catalyse transmembrane movement of substances
    3.6.3.14  H+-transporting two-sector ATPase
     K02147  ATPeVB, ATP6B1; V-type H+-transporting ATPase subunit B

Other DBs

COG:

COG1156

GO:

0046933 0046961

TC:

3.A.2.2

Genes

HSA:	525(ATP6V1B1) 526(ATP6V1B2)
PTR:	464033(ATP6V1B2) 470401(ATP6V1B1)
PPS:	100976103(ATP6V1B1) 100986037(ATP6V1B2)
GGO:	101125715(ATP6V1B2) 101146808(ATP6V1B1)
PON:	100173673(ATP6V1B2) 100449696(ATP6V1B1)
MCC:	703646(ATP6V1B1) 705605(ATP6V1B2)
MMU:	110935(Atp6v1b1) 11966(Atp6v1b2)
RNO:	117596(Atp6v1b2) 312488(Atp6v1b1)
CFA:	474628(ATP6V1B1) 486137(ATP6V1B2)
AML:	100463698 100482823(ATP6V1B1)
FCA:	101092601(ATP6V1B2) 101098295(ATP6V1B1)
BTA:	338059(ATP6V1B1) 338082(ATP6V1B2)
SSC:	100523368 100523998(ATP6V1B2) 100739134
ECB:	100055525
MDO:	100033071
SHR:	100930744(ATP6V1B2)
OAA:	100073907
GGA:	395497(ATP6V1B2)
MGP:	100544578
TGU:	100219912(ATP6V1B2)
ACS:	100554895(atp6v1b2)
XLA:	380305(atp6v1b2) 779272(atp6v1b1)
XTR:	100135740(atp6v1b1) 779628(atp6v1b2)
DRE:	359839(atp6v1ba) 359840(atp6v1b2)
TRU:	101074564
OLA:	101173571(atp6V1Ba)
BFO:	BRAFLDRAFT_126123
CIN:	100186335
SPU:	589417
DME:	Dmel_CG17369(Vha55)
DPO:	Dpse_GA14484
DAN:	Dana_GF23001
DER:	Dere_GG17111
DPE:	Dper_GL13570
DSE:	Dsec_GM25995
DSI:	Dsim_GD20555
DWI:	Dwil_GK13566
DYA:	Dyak_GE24501
DGR:	Dgri_GH18893
DMO:	Dmoj_GI24752
DVI:	Dvir_GJ14577
AGA:	AgaP_AGAP002884
AAG:	AaeL_AAEL005798
CQU:	CpipJ_CPIJ003418
AME:	551721
NVI:	100116861(NV12615)
TCA:	656208
API:	100572714
PHU:	Phum_PHUM253140
ISC:	IscW_ISCW022132
CEL:	CELE_F20B6.2(vha-12) CELE_Y110A7A.12(spe-5)
CBR:	CBG10811(Cbr-tag-300) CBG14362(Cbr-vha-12)
BMY:	Bm1_12010
TSP:	Tsp_06498
SMM:	Smp_029390
NVE:	NEMVE_v1g99968
HMG:	100203652
TAD:	TRIADDRAFT_32492
AQU:	100639470
ATH:	AT1G20260 AT1G76030 AT4G38510
ALY:	ARALYDRAFT_472256 ARALYDRAFT_476752 ARALYDRAFT_490612
GMX:	100791429 100793764 100804483
MTR:	MTR_7g081010
CSV:	101211838 101228138
RCU:	RCOM_0977310 RCOM_1599410
POP:	POPTR_821076 POPTR_831325
VVI:	100243574 100257413
OSA:	4327833 4341339
DOSA:	Os01t0711000-01(Os01g0711000) Os06t0568200-01(Os06g0568200)
BDI:	100835507 100844274 100845199
ZMA:	100282598 100286306
SMO:	SELMODRAFT_269014
PPP:	PHYPADRAFT_106587 PHYPADRAFT_173198 PHYPADRAFT_214369
CRE:	CHLREDRAFT_126382(ATPvB)
VCN:	VOLCADRAFT_110003
OLU:	OSTLU_88387
OTA:	Ot10g00840
CME:	CMP123C
SCE:	YBR127C(VMA2)
AGO:	AGOS_ADL380W
ERC:	Ecym_3439
KLA:	KLLA0D09152g
LTH:	KLTH0F11506g
PPA:	PAS_c131_0021
VPO:	Kpol_538p15
ZRO:	ZYRO0C16984g
CGR:	CAGL0C00649g
NCS:	NCAS_0I00920(NCAS0I00920)
NDI:	NDAI_0A08100(NDAI0A08100)
TPF:	TPHA_0A03440(TPHA0A03440)
TBL:	TBLA_0C02220(TBLA0C02220)
TDL:	TDEL_0C05260(TDEL0C05260)
KAF:	KAFR_0D02530(KAFR0D02530)
DHA:	DEHA2E21846g
PIC:	PICST_48891(VMA2)
PGU:	PGUG_01621
LEL:	LELG_03166
CAL:	CaO19.13955(VMA2) CaO19.6634(VMA2)
CTP:	CTRG_00643
CDU:	CD36_31180
COT:	CORT_0D05450
YLI:	YALI0E27346g
CLU:	CLUG_00735
NCR:	NCU08515
SMP:	SMAC_06242
PAN:	PODANSg6594
TTT:	THITE_2123899
MTM:	MYCTH_2312181
MGR:	MGG_03244
FGR:	FG00637.1
NHE:	NECHADRAFT_98895
VAL:	VDBG_01565
SSL:	SS1G_10682
BFU:	BC1G_04232
ANI:	AN6232.2
NFI:	NFIA_088410
AFM:	AFUA_2G13240
AOR:	AOR_1_532014(AO090026000283)
ANG:	ANI_1_276024(An02g02020)
AFV:	AFLA_136430
ACT:	ACLA_072040
PCS:	Pc22g13480
CIM:	CIMG_05077
CPW:	CPC735_068250
PBL:	PAAG_06288
URE:	UREG_06480
ABE:	ARB_04806
TVE:	TRV_03783
AJE:	HCAG_05951
PNO:	SNOG_07651
PTE:	PTT_12738
ZTR:	MYCGRDRAFT_71411
TML:	GSTUM_00010993001
SPO:	SPAC637.05c(vma2)
CNE:	CNI01180
CNB:	CNBH1120
CGI:	CGB_H1710W
PPL:	POSPLDRAFT_42880
LBC:	LACBIDRAFT_182825
MPR:	MPER_05646
CCI:	CC1G_12318
SCM:	SCHCODRAFT_66894
UMA:	UM01618.1
MGL:	MGL_3123
PGR:	PGTG_04166
ECU:	ECU10_1040
EIN:	Eint_100980
EHE:	EHEL_101050
NCE:	NCER_102049
MBR:	MONBRDRAFT_38294
NGR:	NAEGRDRAFT_55664
DDI:	DDB_G0277401(vatB)
DPP:	DICPUDRAFT_50012
EHI:	EHI_189850(18.t00032)
EDI:	EDI_202200
PFA:	PFD0305c
PFD:	PFDG_00272
PFH:	PFHG_00751
PYO:	PY05102
PCB:	PC001225.02.0
PBE:	PB001177.02.0
PKN:	PKH_030850
PVX:	PVX_000935
PCY:	PCYB_031390
TAN:	TA08450
TPV:	TP04_0441
BBO:	BBOV_II001490(18.m06115)
CPV:	cgd8_1670
CHO:	Chro.80195
TGO:	TGME49_019800
TET:	TTHERM_00529860
PTM:	GSPATT00014624001
TBR:	Tb11.01.3560
TCR:	506025.50 511209.10
LMA:	LMJF_28_2430
LIF:	LINJ_28_2610
LDO:	LDBPK_282610
LMI:	LMXM_28_2430
LBZ:	LBRM_28_2630
GLA:	GL50803_12216
TVA:	TVAG_324980 TVAG_453110
PTI:	PHATRDRAFT_24978
TPS:	THAPSDRAFT_40522(VAT1)
PIF:	PITG_06118

» show all

Reference

PMID:18423392

Authors

Cipriano DJ, Wang Y, Bond S, Hinton A, Jefferies KC, Qi J, Forgac M

Title

Structure and regulation of the vacuolar ATPases.

Journal

Biochim Biophys Acta 1777:599-604 (2008)

Reference

PMID:18406336

Authors

Jefferies KC, Cipriano DJ, Forgac M

Title

Function, structure and regulation of the vacuolar (H+)-ATPases.

Journal

Arch Biochem Biophys 476:33-42 (2008)

All links

Ontology (8)   
   KEGG BRITE (4)   
   GO (2)   
   TC (1)   
   COG (1)   
Pathway (59)   
   KEGG PATHWAY (16)   
   KEGG MODULE (43)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (785)   
   KEGG GENES (223)   
   KEGG DGENES (24)   
   KEGG EGENES (416)   
   KEGG MGENES (122)   
Protein sequence (188)   
   UniProt (188)   
Literature (2)   
   PubMed (2)   
All databases (1044)   

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