KEGG   ORTHOLOGY: K02154Help
Entry
K02154                      KO                                     
Name
ATPeVI, ATP6N1A
Definition
V-type H+-transporting ATPase subunit I [EC:3.6.3.14]
Pathway
Oxidative phosphorylation
Lysosome
Phagosome
Synaptic vesicle cycle
Collecting duct acid secretion
Vibrio cholerae infection
Epithelial cell signaling in Helicobacter pylori infection
Tuberculosis
Rheumatoid arthritis
Module
M00160  
V-type ATPase, eukaryotes
Disease
H00428  
Distal renal tubular acidosis (RTA type 1)
H00436  
Osteopetrosis
H00557  
Cutis laxa
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Energy metabolism
   00190 Oxidative phosphorylation
    K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
   04142 Lysosome
    K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
 Organismal Systems
  Excretory system
   04966 Collecting duct acid secretion
    K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
  Nervous system
   04721 Synaptic vesicle cycle
    K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
 Human Diseases
  Immune diseases
   05323 Rheumatoid arthritis
    K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
  Infectious diseases
   05110 Vibrio cholerae infection
    K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
   05152 Tuberculosis
    K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
KEGG pathway modules [BR:ko00002]
 Structural complex
  Energy metabolism
   ATP synthesis
    M00160  V-type ATPase, eukaryotes
     K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.3  Acting on acid anhydrides to catalyse transmembrane movement of substances
    3.6.3.14  H+-transporting two-sector ATPase
     K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I
BRITE hierarchy
Other DBs
Genes
HSA: 
10312(TCIRG1) 23545(ATP6V0A2) 50617(ATP6V0A4) 535(ATP6V0A1)
PTR: 
452354(ATP6V0A2) 454685(ATP6V0A1) 463765(ATP6V0A4) 466895(TCIRG1)
PPS: 
100971999(ATP6V0A4) 100974286(ATP6V0A2) 100990028(ATP6V0A1) 100995029(TCIRG1)
GGO: 
101139544(ATP6V0A1) 101140521(ATP6V0A4) 101141834(ATP6V0A2) 101148242(TCIRG1)
PON: 
100173661(ATP6V0A1) 100451994(TCIRG1) 100939293(ATP6V0A2)
MCC: 
677865(ATP6V0A1) 710162(ATP6V0A2) 710650(TCIRG1) 715492(ATP6V0A4)
MMU: 
11975(Atp6v0a1) 140494(Atp6v0a4) 21871(Atp6v0a2) 27060(Tcirg1)
RNO: 
116455(Atp6v0a2) 293650(Tcirg1) 296981(Atp6v0a4) 29757(Atp6v0a1)
CFA: 
482779(ATP6V0A4) 483691(TCIRG1) 486245(ATP6V0A2) 607705(ATP6V0A1)
AML: 
FCA: 
101083709(TCIRG1) 101084995(ATP6V0A2) 101089593(ATP6V0A4) 101096367(ATP6V0A1)
BTA: 
286768(ATP6V0A1) 338038(ATP6V0A2) 513684(TCIRG1) 518974(ATP6V0A4) 785923
SSC: 
100154525(ATP6V0A2) 100519402(ATP6V0A4) 100519868 100521769(TCIRG1) 100523018
ECB: 
100052802(ATP6V0A1) 100061140(ATP6V0A2) 100064797(ATP6V0A4) 100146660
MDO: 
100011213(ATP6V0A1) 100013156(TCIRG1) 100017370
SHR: 
100917978(TCIRG1) 100919520(ATP6V0A1) 100934805(ATP6V0A4)
OAA: 
100076253 100092966(ATP6V0A1)
GGA: 
395472(TCIRG1) 395473(ATP6V0A2) 395474(ATP6V0A1) 418104(ATP6V0A4)
MGP: 
100539317 100547817(ATP6V0A4) 100549264 100549598
TGU: 
100218036(ATP6V0A2) 100221499(ATP6V0A4) 100229310(ATP6V0A1) 100231607(TCIRG1)
ACS: 
100559109(tcirg1) 100565909
XLA: 
379986(atp6v0a1) 398897(atp6v0a4)
XTR: 
100036694(atp6v0a1) 100135019(atp6v0a4) 548977(atp6v0a2) 549603(tcirg1)
DRE: 
100003139(tcirg1) 100147923 324307(atp6v0a1a) 406342(tcirg1) 553691(atp6v0a1b) 561117(atp6v0a2b) 561469(atp6v0a2)
TRU: 
101064814 101070581 101071950 101076056 101076155
OLA: 
101155443 101156445 101163575 101164234 101170529
BFO: 
BRAFLDRAFT_125140
CIN: 
100175508
SPU: 
578518
DME: 
Dmel_CG12602(Vha100-5) Dmel_CG1709(Vha100-1) Dmel_CG18617(Vha100-2) Dmel_CG30329(Vha100-3) Dmel_CG7678(Vha100-4)
DPO: 
Dpse_GA11714 Dpse_GA14320 Dpse_GA15015 Dpse_GA15764 Dpse_GA20518
DAN: 
Dana_GF13738 Dana_GF14569 Dana_GF18112 Dana_GF18113 Dana_GF23290
DER: 
Dere_GG11646 Dere_GG16473 Dere_GG20932 Dere_GG23732
DPE: 
Dper_GL10577 Dper_GL19314 Dper_GL23189 Dper_GL23912 Dper_GL24346
DSE: 
Dsec_GM12768 Dsec_GM18705 Dsec_GM19181 Dsec_GM19860
DSI: 
Dsim_GD20170 Dsim_GD23787 Dsim_GD25346
DWI: 
Dwil_GK11490 Dwil_GK11491 Dwil_GK11891 Dwil_GK20688 Dwil_GK24362
DYA: 
Dyak_GE13869 Dyak_GE18538 Dyak_GE23836 Dyak_GE25199 Dyak_GE25200
DGR: 
Dgri_GH11370 Dgri_GH17453 Dgri_GH19224 Dgri_GH19225 Dgri_GH19727
DMO: 
Dmoj_GI18075 Dmoj_GI20149 Dmoj_GI22777 Dmoj_GI24258 Dmoj_GI24259
DVI: 
Dvir_GJ10832 Dvir_GJ10833 Dvir_GJ16665 Dvir_GJ22427 Dvir_GJ22780
AGA: 
AgaP_AGAP001587 AgaP_AGAP001588 AgaP_AGAP003711
AAG: 
AaeL_AAEL003743 AaeL_AAEL006390 AaeL_AAEL014053
CQU: 
CpipJ_CPIJ003274 CpipJ_CPIJ005774 CpipJ_CPIJ017010
AME: 
412810
NVI: 
100116803(NV14086) 100121052(NV15523)
TCA: 
655096 656997
API: 
100161363 100166586
PHU: 
Phum_PHUM018110
ISC: 
IscW_ISCW023371
CEL: 
CELE_F35H10.4(vha-5) CELE_VW02B12L.1(vha-6) CELE_ZK637.8(unc-32)
CBR: 
CBG01592(Cbr-vha-5) CBG02894(Cbr-vha-6) CBG03483(Cbr-vha-7) CBG06881(Cbr-unc-32)
BMY: 
Bm1_31340 Bm1_46445
TSP: 
Tsp_00230
SMM: 
Smp_040970.1
NVE: 
NEMVE_v1g234753
HMG: 
100209321
TAD: 
TRIADDRAFT_63669
ATH: 
AT2G21410(VHA-A2) AT2G28520(VHA-A1) AT4G39080(VHA-A3)
ALY: 
ARALYDRAFT_481007 ARALYDRAFT_490676 ARALYDRAFT_901797
GMX: 
100776037 100783125 100793301 100810062
MTR: 
MTR_2g093210 MTR_4g071070
CSV: 
101209817 101211364 101216514 101224362
RCU: 
RCOM_0624680 RCOM_1449140 RCOM_1596210
POP: 
POPTR_754083 POPTR_801528 POPTR_821153 POPTR_831271
VVI: 
100250193 100255659 100258865
OSA: 
4327412 4332270 4348218
DOSA: 
Os01t0834200-01(Os01g0834200) Os03t0251500-01(Os03g0251500) Os10t0184300-01(Os10g0184300)
BDI: 
100830607 100835973 100845312
SBI: 
SORBI_01g040970(SORBIDRAFT_01g040970) SORBI_03g038990(SORBIDRAFT_03g038990)
SMO: 
SELMODRAFT_109102 SELMODRAFT_182335 SELMODRAFT_184043
PPP: 
PHYPADRAFT_113417 PHYPADRAFT_126569 PHYPADRAFT_134945 PHYPADRAFT_197495 PHYPADRAFT_214893
CRE: 
CHLREDRAFT_115936(ATPvA3) CHLREDRAFT_131895 CHLREDRAFT_438(ATPvA2)
VCN: 
VOLCADRAFT_79461
OLU: 
OSTLU_46292
OTA: 
Ot08g03920
CME: 
CMD095C
SCE: 
YMR054W(STV1) YOR270C(VPH1)
AGO: 
AGOS_ADR127W AGOS_ADR177C
ERC: 
Ecym_2355 Ecym_5436
KLA: 
KLLA0C07491g KLLA0F26477g
LTH: 
KLTH0B04268g KLTH0D12210g
PPA: 
PAS_chr1-3_0066 PAS_chr3_1093
VPO: 
Kpol_1019p1 Kpol_1064p32
ZRO: 
ZYRO0E01496g ZYRO0F09306g
CGR: 
CAGL0C02959g CAGL0F06347g
NCS: 
NCAS_0A08230(NCAS0A08230) NCAS_0B00440(NCAS0B00440)
NDI: 
NDAI_0E00940(NDAI0E00940) NDAI_0G04680(NDAI0G04680)
TPF: 
TPHA_0G00710(TPHA0G00710) TPHA_0N01550(TPHA0N01550)
TBL: 
TBLA_0B03580(TBLA0B03580) TBLA_0C01430(TBLA0C01430)
TDL: 
TDEL_0A06620(TDEL0A06620) TDEL_0B07100(TDEL0B07100)
KAF: 
KAFR_0A04090(KAFR0A04090) KAFR_0B05200(KAFR0B05200)
DHA: 
DEHA2C08712g DEHA2G06776g
PIC: 
PICST_52299(VPH1) PICST_67737(VPH3)
PGU: 
PGUG_02864 PGUG_04169
LEL: 
LELG_04462 LELG_04651
CAL: 
CaO19.1190(VPH1) CaO19.14153 CaO19.6863(VPH1) CaO19.8781(VPH1)
CTP: 
CTRG_03012 CTRG_03894
CDU: 
CD36_44900 CD36_60250
COT: 
CORT_0E03210 CORT_0F04430
YLI: 
YALI0E09933g YALI0F31119g
CLU: 
CLUG_00758 CLUG_02571
NCR: 
NCU03463
SMP: 
SMAC_08441
PAN: 
PODANSg6951
TTT: 
THITE_2123218
MTM: 
MYCTH_2311518
MGR: 
MGG_03947
FGR: 
FG00818.1
NHE: 
NECHADRAFT_90236
VAL: 
VDBG_05276
SSL: 
SS1G_12196
BFU: 
BC1G_01785 BC1G_01786
ANI: 
AN5606.2
NFI: 
NFIA_105210
AFM: 
AFUA_4G11300
AOR: 
AOR_1_1942154(AO090003001090)
ANG: 
ANI_1_886184(An04g05310)
AFV: 
AFLA_027300
ACT: 
ACLA_050390
PCS: 
Pc22g05740
CIM: 
CIMG_01544
CPW: 
CPC735_049120
PBL: 
PAAG_02679
URE: 
UREG_05285
ABE: 
ARB_02317
TVE: 
TRV_05055
AJE: 
HCAG_01585
PNO: 
SNOG_06418
PTE: 
PTT_18920
ZTR: 
MYCGRDRAFT_69748
TML: 
GSTUM_00005345001
SPO: 
SPAC16E8.07c(vph1)
CNE: 
CND02320
CNB: 
CNBD4040
CGI: 
CGB_D4750C
LBC: 
LACBIDRAFT_189552
MPR: 
MPER_08581
CCI: 
CC1G_06089
SCM: 
SCHCODRAFT_66267
UMA: 
UM00630.1
MGL: 
MGL_0542
PGR: 
PGTG_13228
ECU: 
ECU09_1790
EIN: 
Eint_091820
EHE: 
EHEL_091820
NCE: 
NCER_101035
MBR: 
MONBRDRAFT_18895
NGR: 
NAEGRDRAFT_59034
DDI: 
DDB_G0291858(vatM)
DPP: 
DICPUDRAFT_48856
EHI: 
EHI_074020(79.t00005) EHI_107280(105.t00023)
EDI: 
EDI_125500 EDI_253080
PFA: 
PF08_0113
PFD: 
PFDG_00888
PFH: 
PFHG_02638
PYO: 
PY05420
PCB: 
PC300005.00.0
PBE: 
PB000782.00.0
PKN: 
PKH_011150
PVX: 
PVX_088205
PCY: 
PCYB_012040
TAN: 
TA10280
TPV: 
TP04_0731
BBO: 
BBOV_III008300(17.m07725)
CPV: 
cgd4_1470
CHO: 
Chro.40167
TGO: 
TGME49_032830 TGME49_090720
TET: 
TTHERM_00266570 TTHERM_01005210
PTM: 
GSPATT00000458001 GSPATT00007422001 GSPATT00011192001 GSPATT00011472001 GSPATT00015279001 GSPATT00016839001 GSPATT00028971001 PTMB.85c
TBR: 
Tb927.5.1300(Tb05.30H13.310)
TCR: 
509601.70 509767.70 511727.90
LMA: 
LMJF_23_1510 LMJF_32_0920
LIF: 
LINJ_23_1910 LINJ_32_0970
LDO: 
LDBPK_231910 LDBPK_320970
LMI: 
LMXM_23_1510 LMXM_31_0920
LBZ: 
LBRM_23_1750 LBRM_32_1010
GLA: 
GL50803_18470
TVA: 
TVAG_498660
PTI: 
PHATRDRAFT_28794
TPS: 
THAPSDRAFT_40728
PIF: 
PITG_14362
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cipriano DJ, Wang Y, Bond S, Hinton A, Jefferies KC, Qi J, Forgac M
  Title
Structure and regulation of the vacuolar ATPases.
  Journal
Biochim Biophys Acta 1777:599-604 (2008)
Reference
  Authors
Jefferies KC, Cipriano DJ, Forgac M
  Title
Function, structure and regulation of the vacuolar (H+)-ATPases.
  Journal
Arch Biochem Biophys 476:33-42 (2008)
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