KEGG   ORTHOLOGY: K02677Help
Entry
K02677                      KO                                     

Name
CPKC
Definition
classical protein kinase C [EC:2.7.11.13]
Pathway
MAPK signaling pathway
MAPK signaling pathway - yeast
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
Vascular smooth muscle contraction
Wnt signaling pathway
VEGF signaling pathway
Focal adhesion
Tight junction
Gap junction
Natural killer cell mediated cytotoxicity
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Long-term depression
Phototransduction - fly
Inflammatory mediator regulation of TRP channels
Insulin secretion
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Aldosterone-regulated sodium reabsorption
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Amphetamine addiction
Morphine addiction
Vibrio cholerae infection
African trypanosomiasis
Amoebiasis
Hepatitis B
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Disease
H00063  
Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K02677  CPKC; classical protein kinase C
   04015 Rap1 signaling pathway
    K02677  CPKC; classical protein kinase C
   04010 MAPK signaling pathway
    K02677  CPKC; classical protein kinase C
   04011 MAPK signaling pathway - yeast
    K02677  CPKC; classical protein kinase C
   04012 ErbB signaling pathway
    K02677  CPKC; classical protein kinase C
   04310 Wnt signaling pathway
    K02677  CPKC; classical protein kinase C
   04370 VEGF signaling pathway
    K02677  CPKC; classical protein kinase C
   04066 HIF-1 signaling pathway
    K02677  CPKC; classical protein kinase C
   04020 Calcium signaling pathway
    K02677  CPKC; classical protein kinase C
   04070 Phosphatidylinositol signaling system
    K02677  CPKC; classical protein kinase C
   04150 mTOR signaling pathway
    K02677  CPKC; classical protein kinase C
 Cellular Processes
  Cell communication
   04510 Focal adhesion
    K02677  CPKC; classical protein kinase C
   04530 Tight junction
    K02677  CPKC; classical protein kinase C
   04540 Gap junction
    K02677  CPKC; classical protein kinase C
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K02677  CPKC; classical protein kinase C
   04666 Fc gamma R-mediated phagocytosis
    K02677  CPKC; classical protein kinase C
   04670 Leukocyte transendothelial migration
    K02677  CPKC; classical protein kinase C
  Endocrine system
   04911 Insulin secretion
    K02677  CPKC; classical protein kinase C
   04921 Oxytocin signaling pathway
    K02677  CPKC; classical protein kinase C
   04918 Thyroid hormone synthesis
    K02677  CPKC; classical protein kinase C
   04919 Thyroid hormone signaling pathway
    K02677  CPKC; classical protein kinase C
   04916 Melanogenesis
    K02677  CPKC; classical protein kinase C
  Circulatory system
   04270 Vascular smooth muscle contraction
    K02677  CPKC; classical protein kinase C
  Digestive system
   04970 Salivary secretion
    K02677  CPKC; classical protein kinase C
   04971 Gastric acid secretion
    K02677  CPKC; classical protein kinase C
   04972 Pancreatic secretion
    K02677  CPKC; classical protein kinase C
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K02677  CPKC; classical protein kinase C
   04961 Endocrine and other factor-regulated calcium reabsorption
    K02677  CPKC; classical protein kinase C
  Nervous system
   04724 Glutamatergic synapse
    K02677  CPKC; classical protein kinase C
   04727 GABAergic synapse
    K02677  CPKC; classical protein kinase C
   04725 Cholinergic synapse
    K02677  CPKC; classical protein kinase C
   04728 Dopaminergic synapse
    K02677  CPKC; classical protein kinase C
   04726 Serotonergic synapse
    K02677  CPKC; classical protein kinase C
   04720 Long-term potentiation
    K02677  CPKC; classical protein kinase C
   04730 Long-term depression
    K02677  CPKC; classical protein kinase C
   04723 Retrograde endocannabinoid signaling
    K02677  CPKC; classical protein kinase C
  Sensory system
   04745 Phototransduction - fly
    K02677  CPKC; classical protein kinase C
   04750 Inflammatory mediator regulation of TRP channels
    K02677  CPKC; classical protein kinase C
  Environmental adaptation
   04713 Circadian entrainment
    K02677  CPKC; classical protein kinase C
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K02677  CPKC; classical protein kinase C
   05206 MicroRNAs in cancer
    K02677  CPKC; classical protein kinase C
   05205 Proteoglycans in cancer
    K02677  CPKC; classical protein kinase C
   05214 Glioma
    K02677  CPKC; classical protein kinase C
   05223 Non-small cell lung cancer
    K02677  CPKC; classical protein kinase C
  Substance dependence
   05031 Amphetamine addiction
    K02677  CPKC; classical protein kinase C
   05032 Morphine addiction
    K02677  CPKC; classical protein kinase C
  Infectious diseases
   05110 Vibrio cholerae infection
    K02677  CPKC; classical protein kinase C
   05161 Hepatitis B
    K02677  CPKC; classical protein kinase C
   05146 Amoebiasis
    K02677  CPKC; classical protein kinase C
   05143 African trypanosomiasis
    K02677  CPKC; classical protein kinase C
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     K02677  CPKC; classical protein kinase C
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: AGC group
  PKC family [Table]
   K02677  CPKC; classical protein kinase C
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5578(PRKCA) 5579(PRKCB) 5582(PRKCG)
PTR: 
453993(PRKCB) 454832(PRKCA) 456276(PRKCG)
PPS: 
100967981(PRKCA) 100970296(PRKCB) 100990245(PRKCG)
GGO: 
PON: 
MCC: 
701195(PRKCB) 718412(PRKCA) 720263(PRKCG)
MCF: 
101865773(PRKCG) 102116992(PRKCB) 102135875(PRKCA)
MMU: 
18750(Prkca) 18751(Prkcb) 18752(Prkcg)
RNO: 
24680(Prkca) 24681(Prkcg) 25023(Prkcb)
CGE: 
HGL: 
101698346(Prkcg) 101716044(Prkca) 101722702(Prkcb)
TUP: 
102469271(PRKCB) 102495954(PRKCA) 102497204(PRKCG)
CFA: 
100855828 484316(PRKCG) 489968(PRKCB) 490904(PRKCA)
AML: 
FCA: 
101082196(PRKCG) 101086433(PRKCA) 101088970(PRKCB)
BTA: 
282001(PRKCA) 282002(PRKCG) 282325(PRKCB)
BOM: 
102265831(PRKCG) 102278724(PRKCA)
PHD: 
102325983(PRKCA) 102330537(PRKCG) 102337656(PRKCB)
CHX: 
102172114(PRKCB) 102175984(PRKCG) 102180890(PRKCA)
SSC: 
100518074(PRKCG) 100522792 397184(PRKCA)
CFR: 
102507832(PRKCA) 102513516(PRKCG)
ECB: 
100062549(PRKCG) 100063318(PRKCA) 100069215(PRKCB)
MYB: 
102243136(PRKCB) 102249897(PRKCG) 102260557(PRKCA)
MDO: 
SHR: 
100913337(PRKCA) 100924022(PRKCB) 100935225(PRKCG)
OAA: 
GGA: 
416567(PRKCB) 417430(PRKCA)
MGP: 
TGU: 
100219195(PRKCA) 100227442(PRKCB)
FAB: 
101810891(PRKCA) 101820883(PRKCB)
PHI: 
102100311(PRKCA) 102104824(PRKCB)
APLA: 
101799551(PRKCB) 101802546(PRKCA)
FPG: 
101912011(PRKCB) 101914699(PRKCA)
FCH: 
102047370(PRKCB) 102053069(PRKCA)
CLV: 
102084059(PRKCA) 102090291(PRKCB)
ASN: 
102368878(PRKCB) 102371860(PRKCG) 102377784(PRKCA)
PSS: 
102449325(PRKCB) 102459336(PRKCA)
ACS: 
XLA: 
447031(prkca)
XTR: 
100038043(prkcb) 100496779(prkcg) 780209(prkca)
DRE: 
100003514(prkcg) 100006675(prkcba) 393953(prkcbb) 497384(prkca)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
BFO: 
CIN: 
100186768(prkca)
SPU: 
DME: 
Dmel_CG6518(inaC) Dmel_CG6622(Pkc53E)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
406106(Pkc)
NVI: 
BMOR: 
692526(Cpkc)
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG16150(Cbr-pkc-2)
BMY: 
LOA: 
TSP: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
SCE: 
YBL105C(PKC1)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0E03010(NCAS0E03010)
NDI: 
NDAI_0E04610(NDAI0E04610)
TPF: 
TPHA_0B01520(TPHA0B01520)
TBL: 
TBLA_0I00910(TBLA0I00910)
TDL: 
TDEL_0C03050(TDEL0C03050)
KAF: 
KAFR_0G01080(KAFR0G01080)
DHA: 
PIC: 
PGU: 
LEL: 
CAL: 
CTP: 
CDU: 
COT: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
MGR: 
FGR: 
NHE: 
VAL: 
SSL: 
BFU: 
NFI: 
AFM: 
AOR: 
AOR_1_552094(AO090120000316)
AFV: 
ACT: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
ZTR: 
SPO: 
CNE: 
CNB: 
LBC: 
MPR: 
CCI: 
SCM: 
MGL: 
PGR: 
MBR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Newton AC
  Title
Protein kinase C: poised to signal.
  Journal
Am J Physiol Endocrinol Metab 298:E395-402 (2010)
Reference
PMID:9792904
  Authors
Toker A
  Title
Signaling through protein kinase C.
  Journal
Front Biosci 3:D1134-47 (1998)

DBGET integrated database retrieval system