KEGG   ORTHOLOGY: K03083Help
Entry
K03083                      KO                                     

Name
GSK3B
Definition
glycogen synthase kinase 3 beta [EC:2.7.11.26]
Pathway
ErbB signaling pathway
Chemokine signaling pathway
Cell cycle
PI3K-Akt signaling pathway
Wnt signaling pathway
Hedgehog signaling pathway
Axon guidance
Hippo signaling pathway
Focal adhesion
T cell receptor signaling pathway
B cell receptor signaling pathway
Circadian rhythm - fly
Neurotrophin signaling pathway
Dopaminergic synapse
Insulin signaling pathway
Melanogenesis
Prolactin signaling pathway
Thyroid hormone signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Alzheimer's disease
Hepatitis C
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Colorectal cancer
Endometrial cancer
Prostate cancer
Basal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
   04310 Wnt signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
   04340 Hedgehog signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
   04390 Hippo signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
   04151 PI3K-Akt signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K03083  GSK3B; glycogen synthase kinase 3 beta
  Cell communication
   04510 Focal adhesion
    K03083  GSK3B; glycogen synthase kinase 3 beta
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
   04662 B cell receptor signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
   04062 Chemokine signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
  Endocrine system
   04910 Insulin signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
   04917 Prolactin signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
   04919 Thyroid hormone signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
   04916 Melanogenesis
    K03083  GSK3B; glycogen synthase kinase 3 beta
  Nervous system
   04728 Dopaminergic synapse
    K03083  GSK3B; glycogen synthase kinase 3 beta
   04722 Neurotrophin signaling pathway
    K03083  GSK3B; glycogen synthase kinase 3 beta
  Development
   04360 Axon guidance
    K03083  GSK3B; glycogen synthase kinase 3 beta
  Environmental adaptation
   04711 Circadian rhythm - fly
    K03083  GSK3B; glycogen synthase kinase 3 beta
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K03083  GSK3B; glycogen synthase kinase 3 beta
   05210 Colorectal cancer
    K03083  GSK3B; glycogen synthase kinase 3 beta
   05217 Basal cell carcinoma
    K03083  GSK3B; glycogen synthase kinase 3 beta
   05215 Prostate cancer
    K03083  GSK3B; glycogen synthase kinase 3 beta
   05213 Endometrial cancer
    K03083  GSK3B; glycogen synthase kinase 3 beta
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K03083  GSK3B; glycogen synthase kinase 3 beta
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K03083  GSK3B; glycogen synthase kinase 3 beta
  Infectious diseases
   05166 HTLV-I infection
    K03083  GSK3B; glycogen synthase kinase 3 beta
   05162 Measles
    K03083  GSK3B; glycogen synthase kinase 3 beta
   05164 Influenza A
    K03083  GSK3B; glycogen synthase kinase 3 beta
   05160 Hepatitis C
    K03083  GSK3B; glycogen synthase kinase 3 beta
   05169 Epstein-Barr virus infection
    K03083  GSK3B; glycogen synthase kinase 3 beta
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     K03083  GSK3B; glycogen synthase kinase 3 beta
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: CMGC group
  GSK family [OT]
   K03083  GSK3B; glycogen synthase kinase 3 beta
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centrosomal proteins
   Kinases and associated factors
    K03083  GSK3B; glycogen synthase kinase 3 beta
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
2932(GSK3B)
PTR: 
100616510(GSK3B)
PPS: 
100972306(GSK3B)
GGO: 
101125534(GSK3B)
PON: 
100447772(GSK3B)
MCC: 
713114(GSK3B)
MCF: 
102133756(GSK3B)
MMU: 
56637(Gsk3b)
RNO: 
84027(Gsk3b)
CGE: 
100760865(Gsk3b)
HGL: 
101701301(Gsk3b)
TUP: 
102476038(GSK3B)
CFA: 
478575(GSK3B)
AML: 
100479224(GSK3B)
FCA: 
101081660(GSK3B)
PTG: 
102961382(GSK3B)
BTA: 
790875(GSK3B)
BOM: 
102275260(GSK3B)
PHD: 
102335629(GSK3B)
CHX: 
102176363(GSK3B)
SSC: 
100126852(GSK3B)
CFR: 
102504696(GSK3B)
BACU: 
102998893(GSK3B)
LVE: 
103074757(GSK3B)
ECB: 
100061033(GSK3B)
MYB: 
102248758(GSK3B)
MYD: 
102751662(GSK3B)
PALE: 
102882441(GSK3B)
MDO: 
100012447(GSK3B)
SHR: 
100920192(GSK3B)
OAA: 
GGA: 
418335(GSK3B)
MGP: 
TGU: 
100224604(GSK3B)
FAB: 
101807423(GSK3B)
PHI: 
102105491(GSK3B)
APLA: 
101802112(GSK3B)
FPG: 
101918255(GSK3B)
FCH: 
102059271(GSK3B)
CLV: 
102090893(GSK3B)
ASN: 
102387985(GSK3B)
AMJ: 
102569716(GSK3B)
PSS: 
102461748(GSK3B)
CMY: 
102935600(GSK3B)
ACS: 
100564023(gsk3b)
PBI: 
103066659(GSK3B)
XLA: 
399097(gsk3b)
XTR: 
100489648(gsk3b)
DRE: 
30654(gsk3b) 560194(gsk3aa)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102350787(GSK3B)
CMK: 
103180204(gsk3b)
BFO: 
CIN: 
445595(gsk)
SPU: 
764638(gsk3b)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
408976(sgg)
NVI: 
TCA: 
664299(sgg)
BMOR: 
PHU: 
ISC: 
CEL: 
CELE_C44H4.6(C44H4.6) CELE_R03D7.5(R03D7.5) CELE_Y18D10A.5(gsk-3)
CBR: 
BMY: 
LOA: 
TSP: 
NVE: 
HMG: 
TAD: 
AQU: 
100616537(Gsk3)
ATH: 
AT1G57870(SK42) AT5G14640(SK13)
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0296100-01(Os01g0296100) Os03t0841800-01(Os03g0841800) Os05t0134000-01(Os05g0134000)
OBR: 
BDI: 
SBI: 
SORBI_01g001760(SORBIDRAFT_01g001760) SORBI_03g009580(SORBIDRAFT_03g009580) SORBI_09g002710(SORBIDRAFT_09g002710)
ZMA: 
100273692 100282499 100283734(pco153236) 542518(gpm645)
SITA: 
ATR: 
s00003p00196730(AMTR_s00003p00196730) s00019p00105860(AMTR_s00019p00105860) s00069p00059670(AMTR_s00069p00059670) s00071p00186380(AMTR_s00071p00186380) s00096p00102520(AMTR_s00096p00102520)
SMO: 
PPP: 
CRE: 
VCN: 
OTA: 
MIS: 
MPP: 
CVR: 
CME: 
GSL: 
PPA: 
DHA: 
PIC: 
PGU: 
LEL: 
SPAA: 
CAL: 
CaO19.1593(RIM11)
CTP: 
CDU: 
COT: 
CTEN: 
YLI: 
CLU: 
NCR: 
SMP: 
SMAC_04408(rim11)
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_46114(AO090701000024)
ANG: 
ANI_1_32134(An15g00170)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
PNO: 
PTE: 
BZE: 
ZTR: 
PFJ: 
BCOM: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
LBC: 
CCI: 
SCM: 
UMA: 
MGL: 
PGR: 
ECU: 
EIN: 
EHE: 
MBR: 
DDI: 
DPP: 
DFA: 
DFA_06870(gskA) DFA_08988(glkA)
EHI: 
EHI_003900(370.t00002) EHI_121880(147.t00016)
EDI: 
ACAN: 
PFA: 
PFC0525c(PfGSK-3)
PFH: 
PYO: 
PCB: 
PBE: 
PKN: 
PVX: 
PCY: 
TAN: 
BEQ: 
CPV: 
CHO: 
TGO: 
TET: 
PTM: 
PTI: 
TPS: 
PIF: 
EHX: 
GTT: 
NGR: 
TVA: 
GLA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Rayasam GV, Tulasi VK, Sodhi R, Davis JA, Ray A
  Title
Glycogen synthase kinase 3: more than a namesake.
  Journal
Br J Pharmacol 156:885-98 (2009)
Reference
  Authors
Bobinnec Y, Morin X, Debec A
  Title
Shaggy/GSK-3beta kinase localizes to the centrosome and to specialized cytoskeletal structures in Drosophila.
  Journal
Cell Motil Cytoskeleton 63:313-20 (2006)

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